Jobs in the United States

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Added 4 mins ago
CM
Maintenance Shift Supervisor
Cayuga Milk Ingredients, LLC
Auburn, NY
- $34.15 to $48.5 USD / hour
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Added 5 mins ago
Chemical Engineer - Direct Liquid Cooling
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Added 11 mins ago
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Qualifications You Must Have:
Added 14 mins ago
Night Maintenance Technician – Lennox Hotel Miami Beach
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Report major technical issues and follow up with the Chief Engineer when additional support or specialized repairs are required.
Added 15 mins ago
Assembler
Spirax-Sarco Ltd.
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operations by assembling products to defined specifications, ensuring high
Added 15 mins ago
Assembler
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Added 20 mins ago
Senior Electrical Engineer
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Added 20 mins ago
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Remote, United States
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Added 21 mins ago
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Added 27 mins ago
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Added 33 mins ago
JL
Operating Engineer (3rd Shift)
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Thornton, CO
- $65,120 to $81,400 USD / year
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Added 33 mins ago
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- $40,123 USD / year
Review training literature for technical accuracy including installation guides and procedures, operations manuals, and online learning.
Added 34 mins ago
Principal Engineer
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Gurugram Gurgaon HR, IN
14,000+ engaged teammates globally with operations in 25 countries across the globe.
Added 39 mins ago
HC
Manufacturing Engineer II
Haemonetics Corporation
Clinton, PA
- $68,200 to $116,000 USD / year
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Added 43 mins ago
Instructor Regional Rail (9162)
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Added 45 mins ago
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Sulphur, OK
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Added 45 mins ago
Senior Electrical Manufacturing Engineer, Advanced Operations Engineering Google Data Center
Google
Sunnyvale, CA
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Added 47 mins ago
Senior Software Engineer, Full Stack and Advanced Algorithms
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Master's degree or PhD in Computer Science, Mathematics, or a related technical field.
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Added 47 mins ago
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4 years of experience working in a hardware design, bring-up, and debugging technical environment, or 3 years of experience with an advanced degree.
Added 47 mins ago
Software Engineer, Knowledge Catalog For AI
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Master's degree or PhD in Computer Science or related technical fields.
Added 47 mins ago
Software Engineering Manager, Remote Direct Memory Access Networking
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Added 48 mins ago
Summer Research Program 2027, Cyber-Physical Systems (Group 05-51)
MIT Lincoln Laboratory
Lexington, MA
…warfare capabilities. The intern will work alongside experienced technical staff on projects that may involve cyber operations, electronic warfare, RF systems, signal processing, artificial…
Added 59 mins ago
Operations Support Engineer
Vantor Inc.
Longmont, CO · Westminster, CO
Vantor is seeking an Operations Support Engineer to join a mission-focused technical operations team supporting satellite ground systems and 24x7 operational readiness. This role is heavily…
Added 1 hour ago
Manufacturing Technician, Thurs-Sat + every other Wed, 6 am to 6:30 pm
Entegris, Inc.
Bedford, MA
Notifies Process Engineer and / or Production Supervisor of any discrepancies to ensure quality standards and safety of operations are always maintained.

Senior Software Engineer - Lab Automation

United States

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.

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Job details

Pay: The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.
Experience: 5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Posting language: English
Posted: Nov 4, 2026

Original job description

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organizations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximizing these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence to assist our scientists to deliver more innovative and transformative medicines for patients worldwide.

The Opportunity

At Genentech (gRED) and Roche (pRED), we’re applying software, robotics, and advanced AI to solve one of humanity’s hardest challenges: building fully autonomous, self-healing laboratories for lights-out drug discovery. Advances in AI, data, and computational sciences are transforming drug discovery and development. The Computational Sciences Center of Excellence (CoE) and the Data and Digital Catalyst (DDC) team are building the foundational platform for autonomous labs - turning frontier AI models, rich physical telemetry, and multi-vendor robotics into resilient, intelligent systems that run complex science unattended around the clock to deliver life-saving medicines to patients faster than ever before.

As a Senior Software Engineer – Lab Automation, you will be the essential bridge connecting software architecture, frontier AI models, and real-world physical instrumentation. You will architect the hardware abstraction layers, instrument integration frameworks, and orchestration engines that allow diverse lab automation platforms to operate with seamless reliability and closed-loop error recovery. If you are inspired by the challenge of building a robust software backbone powering autonomous science, this is your opportunity to pioneer the next generation of automated laboratories at global scale.

In this role, you will:

Design, program, and troubleshoot high-throughput lab workflows ensuring robust assay execution on physical hardware.
Build orchestration systems, hardware abstraction layers, and instrument drivers that manage retries, handle shared resource contention, and enable 24/7 unattended operation.
Implement telemetry, logging, metrics, and alerting across hardware and software to diagnose failures and resolve root causes using software hooks or vision models rather than relying on manual workarounds.
Build systems to maintain an accurate real-time digital representation of the lab, including sample tracking, instrument state, and reagent availability, with bidirectional integration into LIMS and ELNs.
Manage hardware requirements, site constraints, communication protocols, and workcell integration from initial mechanical layout and prototyping through production deployment.
Work directly with software engineers, automation scientists, and hardware engineers to translate complex scientific protocols into production-grade technical architectures.

Who you are

5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Proficient in Python or C# for building modular software architectures, integration frameworks, and distributed services.
Strong software engineering fundamentals, including system design, automated testing, version control, CI/CD, debugging, and production operations.
AI-native software engineer with effective practices for providing context, decomposing problems, directing agents, reviewing their work, and validating results. Deep understanding of the limitations of AI-generated code.
Hands-on experience programming commercial liquid-handling platforms and integrating robotic arms or manipulators into unified automated workcells.
Experienced in designing workflow orchestration and scheduling systems that manage shared resources, dynamic dependencies, and execution priorities.
Skilled at leveraging APIs and SDKs (such as REST, gRPC, and vendor interfaces) to interact with complex laboratory software ecosystems.
Practical rapid-prototyping design experience, including CAD, 3D printing, CNC milling, or laser cutting for custom fixtures and hardware adaptations.
Familiar with molecular biology, biochemistry, or wet-lab workflows, enabling effective translation between scientific requirements and engineering deliverables.
Clear communicator adept at collaborating across multidisciplinary teams spanning research scientists, software developers, and automation engineers.

Preferred, but not required

Experience creating and evaluating AI agents used within applications, including designing robust evals to measure agent performance and reliability.
Experience integrating computer vision models (such as OpenCV, YOLO, or SAM) for automated error recovery, deck inspection, and anomaly detection.
Hands-on background in training, evaluating, or adopting AI/ML models, including reinforcement learning or imitation learning for robotics.
Knowledgeable about sensors, microcontrollers, embedded communication protocols, and task-and-motion planning.
Familiar with cloud infrastructure, containerized deployment, and digital twin simulation workflows.

Relocation benefits are not available for this opportunity

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

#ComputationCoE #tech4lifeComputationalScience

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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More about this job

Skills

Robotics
Troubleshoot
LIMS
Communication skills
Python
C#
Test automation
CI/CD
Debugging
Workflow
Scheduling
3D Printing
CNC
Operate laser cutting equipment
Molecular biology
Translation
Research
SAM
Inspection
ML

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Work requirements

Jobs in the United States