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Added 14 mins ago
Sr Reliability Engineer
Drägerwerk AG & Co. KGaA
Andover, MA
The Senior Reliability Engineer coordinates and supports efforts to establish product reliability goals and to plan, execute and monitor activities aimed at achieving those goals. Work with…
Added 37 mins ago
Senior Electrical Control Panel Engineer
Alten USA
Berkeley, CA
We are hiring a Senior Control Panel Designer to impact development and validation of our groundbreaking battery technology. As part of our BMS Hardware & Electrical System team, you will…
Added 38 mins ago
Senior/Principal Cybersecurity - Systems Security Engineering, Onsite
Sandia National Laboratories
Livermore, CA
…advanced cyber threats? Would you like to contribute to the development of Sandia's risk management framework for digital systems? Are you up for the challenge to help enact a new vision…
Added 38 mins ago
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CXR Senior Process & Integration Engineer
Stanford University
Stanford, CA
- $168,360 to $197,495 USD / year
Stanford University leads the Northwest AI Hardware Hub (NWAI Hub), one of the national hubs in the CHIPS Act-funded Microelectronics Commons initiative. With its administrative center at…
Added 39 mins ago
Mid-level or Senior Modeling and Simulation Engineer
The Boeing Company
El Segundo, CA
The Boeing Space & Launch team is seeking a Mid-level or Senior Modeling and Simulation Engineer for development projects in El Segundo, CA and Mesa, AZ . The Space and Launch Team creates…
Added 39 mins ago
Space Vehicle Design Engineer (Experienced, Senior or Lead)
The Boeing Company
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…Information Systems (SW&IS) is seeking a Space Vehicle Design Engineer (Experienced, Senior or Lead) in El Segundo, California…
Added 39 mins ago
Antenna SubSystems Engineer, - Associate, Mid-Career or Senior
The Boeing Company
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Be part of a systems engineering team that specializes in antenna subsystem design and development for satellite systems. Work with large cross-functional teams including customers,…
Added 39 mins ago
Antenna SubSystems Engineer – Associate, Mid-Level, or Senior
The Boeing Company
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Added 39 mins ago
Systems Engineer - Digital Signal Processing (Associate or Mid-level)
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…trades, concept studies and system definition, to satellite unit development and test. You will belong to a systems engineering team interacting with customers, suppliers, program…
Added 39 mins ago
Senior Electrical Engineer- Power Conversion
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Irvine, CA
This position provides senior electrical engineering leadership for the design, development, and qualification of power conversion electronics used in Battery Back Up (BBU) and…
Added 39 mins ago
Senior Software Engineer, Performance, Platforms Infrastructure Engineering
Google
Sunnyvale, CA
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Added 39 mins ago
Senior Staff Software Engineer, Agent Registry
Google
Sunnyvale, CA
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Added 39 mins ago
Senior Software Engineer, Security Infrastructure
Google
Sunnyvale, CA
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Added 39 mins ago
Senior Signal and Power Integrity Engineer
Google
Sunnyvale, CA
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Added 40 mins ago
Engineer VII
General Atomics
San Diego, CA
We are seeking a highly experienced Senior Pulsed Power Technologist to provide senior technical leadership for pulsed-power systems supporting railgun, electric launch, and related…
Added 40 mins ago
Senior Software Engineer, Infrastructure, Google Workspace
Google
Los Angeles, CA
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Added 41 mins ago
Programmer
BOOZ, ALLEN & HAMILTON, INC.
Camp Pendleton, CA
As a senior embedded software engineer at Booz Allen, you'll support the development of systems, sites, and tools for our clients. Using the latest tools and technology, you'll write, test,…
Added 41 mins ago
Senior Staff Hardware Engineer
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Milpitas, CA
The successful candidate will be a key hardware technical leader, working across ASIC, system architecture, system design, firmware, package engineering, and validation teams to turn new…
Added 1 hour ago
AI Engineer - US Remote
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Remote, United States
Ship models to production under latency, memory, and cost limits, on cloud GPUs and edge hardware (TensorRT, ONNX, Jetson or similar).
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Senior Chassis Engineer
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Riverside, CA
The Senior Chassis Engineer will own the mechanical integration and validation of axles, suspension interfaces, pneumatic and air brake systems, steering systems, and related vehicle…
Added 2 hours ago
Sr. Aerospace Hardware Reliability Engineer, Prime Air
Amazon.com Services LLC
Seattle, WA
Amazon Prime Air is seeking a Senior Hardware Reliability Engineer to define and lead reliability strategy for hardware used in airborne systems. You will develop reliability requirements,…
Added 2 hours ago
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Principal Optical Engineer - Remote
Oracle
Jefferson City, MO
- $114,600 to $234,600 USD / year
The Principal Optical Engineer will be joining the Optical Network Engineering team which is responsible for building and scaling Oracle's Optical Transport Network. The team is focused on…
Added 2 hours ago
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Senior Power Electronics Engineer
True Talent Solutions Partners
Torrance, CA
- $150,000 to $200,000 USD / year
- Own hardware development from schematic design through bring-up, debugging, validation, and production integration.
Added 2 hours ago
Senior Constructability Engineer, Data Center Design Engineering
Amazon Data Services, Inc.
Austin, TX · Seattle, WA · Herndon, VA
As a Senior Constructability Engineer you are forward-deployed into constructability problems rather than reviewing them from a distance. You embed alongside the teams that own the work -…
Added 2 hours ago
Data Center Regional Chief Engineer
Amazon Data Services, Inc.
Ridgeland, MS
Amazon Web Services (AWS) is looking for a highly motivated Regional Chief Engineer (CE) to join our Data Center Engineering Operations (DCEO) Team. This committed group works to maintain…

Senior Software Engineer - Lab Automation

United States

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.

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Job details

Pay: The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.
Experience: 5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Posting language: English
Posted: Nov 4, 2026

Original job description

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organizations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximizing these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence to assist our scientists to deliver more innovative and transformative medicines for patients worldwide.

The Opportunity

At Genentech (gRED) and Roche (pRED), we’re applying software, robotics, and advanced AI to solve one of humanity’s hardest challenges: building fully autonomous, self-healing laboratories for lights-out drug discovery. Advances in AI, data, and computational sciences are transforming drug discovery and development. The Computational Sciences Center of Excellence (CoE) and the Data and Digital Catalyst (DDC) team are building the foundational platform for autonomous labs - turning frontier AI models, rich physical telemetry, and multi-vendor robotics into resilient, intelligent systems that run complex science unattended around the clock to deliver life-saving medicines to patients faster than ever before.

As a Senior Software Engineer – Lab Automation, you will be the essential bridge connecting software architecture, frontier AI models, and real-world physical instrumentation. You will architect the hardware abstraction layers, instrument integration frameworks, and orchestration engines that allow diverse lab automation platforms to operate with seamless reliability and closed-loop error recovery. If you are inspired by the challenge of building a robust software backbone powering autonomous science, this is your opportunity to pioneer the next generation of automated laboratories at global scale.

In this role, you will:

Design, program, and troubleshoot high-throughput lab workflows ensuring robust assay execution on physical hardware.
Build orchestration systems, hardware abstraction layers, and instrument drivers that manage retries, handle shared resource contention, and enable 24/7 unattended operation.
Implement telemetry, logging, metrics, and alerting across hardware and software to diagnose failures and resolve root causes using software hooks or vision models rather than relying on manual workarounds.
Build systems to maintain an accurate real-time digital representation of the lab, including sample tracking, instrument state, and reagent availability, with bidirectional integration into LIMS and ELNs.
Manage hardware requirements, site constraints, communication protocols, and workcell integration from initial mechanical layout and prototyping through production deployment.
Work directly with software engineers, automation scientists, and hardware engineers to translate complex scientific protocols into production-grade technical architectures.

Who you are

5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Proficient in Python or C# for building modular software architectures, integration frameworks, and distributed services.
Strong software engineering fundamentals, including system design, automated testing, version control, CI/CD, debugging, and production operations.
AI-native software engineer with effective practices for providing context, decomposing problems, directing agents, reviewing their work, and validating results. Deep understanding of the limitations of AI-generated code.
Hands-on experience programming commercial liquid-handling platforms and integrating robotic arms or manipulators into unified automated workcells.
Experienced in designing workflow orchestration and scheduling systems that manage shared resources, dynamic dependencies, and execution priorities.
Skilled at leveraging APIs and SDKs (such as REST, gRPC, and vendor interfaces) to interact with complex laboratory software ecosystems.
Practical rapid-prototyping design experience, including CAD, 3D printing, CNC milling, or laser cutting for custom fixtures and hardware adaptations.
Familiar with molecular biology, biochemistry, or wet-lab workflows, enabling effective translation between scientific requirements and engineering deliverables.
Clear communicator adept at collaborating across multidisciplinary teams spanning research scientists, software developers, and automation engineers.

Preferred, but not required

Experience creating and evaluating AI agents used within applications, including designing robust evals to measure agent performance and reliability.
Experience integrating computer vision models (such as OpenCV, YOLO, or SAM) for automated error recovery, deck inspection, and anomaly detection.
Hands-on background in training, evaluating, or adopting AI/ML models, including reinforcement learning or imitation learning for robotics.
Knowledgeable about sensors, microcontrollers, embedded communication protocols, and task-and-motion planning.
Familiar with cloud infrastructure, containerized deployment, and digital twin simulation workflows.

Relocation benefits are not available for this opportunity

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

#ComputationCoE #tech4lifeComputationalScience

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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More about this job

Skills

Robotics
Troubleshoot
LIMS
Communication skills
Python
C#
Test automation
CI/CD
Debugging
Workflow
Scheduling
3D Printing
CNC
Operate laser cutting equipment
Molecular biology
Translation
Research
SAM
Inspection
ML

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Work requirements

Jobs in the United States