Jobs in the United States

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MI
Resident Project Representative (RPR) - Aviation Construction
McFarland-Johnson, Inc
Binghamton, NY
- $50 to $60 USD / hour
Observe construction activities involving pavement rehabilitation and reconstruction, earthwork, drainage, utilities, airfield electrical systems, and related infrastructure.
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NY
Professional Engineer 1 (Environmental) - NY HELPS
New York State Civil Service
Albany, NY
- $102,406 to $127,439 USD / year
Duties Description Under the general direction and supervision of the Source Control and Technology Section Chief, the Professional Engineer 1 (Environmental) will support the…
Added 6 mins ago
A
Vision Engineer
Actalent
Wixom, MI
- $40 to $48 USD / hour
Job Title: Vision EngineerJob DescriptionThis contract Vision Engineer role supports a critical automation integration project based in Wixom, MI, with subsequent installation work in…
Added 6 mins ago
A
Controls Engineer
Actalent
Wixom, MI
- $40 to $48 USD / hour
Participate in installation, startup, and validation of control systems at the Romulus facility.
Added 6 mins ago
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Robotic Engineer
Actalent
Wixom, MI
- $40 to $48 USD / hour
…on-site installation work at a customer facility. As a Robotic Engineer, you will apply your expertise in GRS or iRVision to develop, integrate, and optimize robotic systems, working…
Added 9 mins ago
Senior Electrical Engineer (Generation)
WSP
Meridian, ID · Seattle, WA · Houston, TX · Mount Laurel, NJ · Oradell, NJ · Atlanta, GA · Overland Park, KS · Tulsa, OK · Phoenix, AZ · Boise, ID · Hailey, ID
…power regulation, renewable energy, as well as protection and control systems in a wide variety of contexts (utilities, transportation, building, and Federal, State, and local government…
Added 12 mins ago
TA
SPACE NORTH Theater Support Lead
The Aerospace Corpor
Colorado Springs, CO
- $151,300 to $226,900 USD / year
…innovative solutions that span satellite, launch, ground, and cyber systems for defense, civil and commercial customers. When you join our team, you'll be part of a special collection of…
Added 12 mins ago
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Space Vehicle and Electronic Component Structural Engineer
The Aerospace Corpor
Colorado Springs, CO
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The Vehicle Systems Division (VSD) sits at the center of the ideas and data behind current and future space systems supplying innovative research and development; technical evaluations…
Added 15 mins ago
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Victaulic Company
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CoreLogic Solutions, LLC
Dallas, TX
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Added 26 mins ago
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Dallas, TX
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DevOps Engineer
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…support infrastructure, operations, and project work. The DevOps Engineer supports production systems and may occasionally require planned after-hours deployment or maintenance…
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Staff Process Engineer, Drive Unit (3rd Shift)
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Added 41 mins ago
Automation Controls Engineer
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Added 49 mins ago
RU
Manufacturing Engineer
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Wheeling, IL
- $100,000 to $130,000 USD / year
Our Client is seeking a skilled and hands-on Manufacturing Engineer to support their CNC and Swiss CNC precision machining operations. In this role, you will act as the technical bridge…
Added 50 mins ago
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Staff Software Architect Engineer - Level 5
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Fort Collins, CO
- $27.16 to $35 USD / hour
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Added 50 mins ago
Critical Infrastructure Senior Mechanical Engineer- Data Center and Rack Testing Facility, Field Engineering
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Sr. Mechanical Engineer
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Northrop Grumman Space Systems - Missile Defense Integration offers an excellent opportunity for a Principal Software Engineer (26-434) to join our team of skilled and diverse…

Senior Software Engineer - Lab Automation

United States

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.

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Job details

Pay: The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.
Experience: 5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Posting language: English
Posted: Nov 4, 2026

Original job description

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organizations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximizing these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence to assist our scientists to deliver more innovative and transformative medicines for patients worldwide.

The Opportunity

At Genentech (gRED) and Roche (pRED), we’re applying software, robotics, and advanced AI to solve one of humanity’s hardest challenges: building fully autonomous, self-healing laboratories for lights-out drug discovery. Advances in AI, data, and computational sciences are transforming drug discovery and development. The Computational Sciences Center of Excellence (CoE) and the Data and Digital Catalyst (DDC) team are building the foundational platform for autonomous labs - turning frontier AI models, rich physical telemetry, and multi-vendor robotics into resilient, intelligent systems that run complex science unattended around the clock to deliver life-saving medicines to patients faster than ever before.

As a Senior Software Engineer – Lab Automation, you will be the essential bridge connecting software architecture, frontier AI models, and real-world physical instrumentation. You will architect the hardware abstraction layers, instrument integration frameworks, and orchestration engines that allow diverse lab automation platforms to operate with seamless reliability and closed-loop error recovery. If you are inspired by the challenge of building a robust software backbone powering autonomous science, this is your opportunity to pioneer the next generation of automated laboratories at global scale.

In this role, you will:

Design, program, and troubleshoot high-throughput lab workflows ensuring robust assay execution on physical hardware.
Build orchestration systems, hardware abstraction layers, and instrument drivers that manage retries, handle shared resource contention, and enable 24/7 unattended operation.
Implement telemetry, logging, metrics, and alerting across hardware and software to diagnose failures and resolve root causes using software hooks or vision models rather than relying on manual workarounds.
Build systems to maintain an accurate real-time digital representation of the lab, including sample tracking, instrument state, and reagent availability, with bidirectional integration into LIMS and ELNs.
Manage hardware requirements, site constraints, communication protocols, and workcell integration from initial mechanical layout and prototyping through production deployment.
Work directly with software engineers, automation scientists, and hardware engineers to translate complex scientific protocols into production-grade technical architectures.

Who you are

5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Proficient in Python or C# for building modular software architectures, integration frameworks, and distributed services.
Strong software engineering fundamentals, including system design, automated testing, version control, CI/CD, debugging, and production operations.
AI-native software engineer with effective practices for providing context, decomposing problems, directing agents, reviewing their work, and validating results. Deep understanding of the limitations of AI-generated code.
Hands-on experience programming commercial liquid-handling platforms and integrating robotic arms or manipulators into unified automated workcells.
Experienced in designing workflow orchestration and scheduling systems that manage shared resources, dynamic dependencies, and execution priorities.
Skilled at leveraging APIs and SDKs (such as REST, gRPC, and vendor interfaces) to interact with complex laboratory software ecosystems.
Practical rapid-prototyping design experience, including CAD, 3D printing, CNC milling, or laser cutting for custom fixtures and hardware adaptations.
Familiar with molecular biology, biochemistry, or wet-lab workflows, enabling effective translation between scientific requirements and engineering deliverables.
Clear communicator adept at collaborating across multidisciplinary teams spanning research scientists, software developers, and automation engineers.

Preferred, but not required

Experience creating and evaluating AI agents used within applications, including designing robust evals to measure agent performance and reliability.
Experience integrating computer vision models (such as OpenCV, YOLO, or SAM) for automated error recovery, deck inspection, and anomaly detection.
Hands-on background in training, evaluating, or adopting AI/ML models, including reinforcement learning or imitation learning for robotics.
Knowledgeable about sensors, microcontrollers, embedded communication protocols, and task-and-motion planning.
Familiar with cloud infrastructure, containerized deployment, and digital twin simulation workflows.

Relocation benefits are not available for this opportunity

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

#ComputationCoE #tech4lifeComputationalScience

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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More about this job

Skills

Robotics
Troubleshoot
LIMS
Communication skills
Python
C#
Test automation
CI/CD
Debugging
Workflow
Scheduling
3D Printing
CNC
Operate laser cutting equipment
Molecular biology
Translation
Research
SAM
Inspection
ML

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