Jobs in the United States

25+ jobs

Added 2 mins ago
Architect, Enterprise AI
Navitus
Lansing, MI
Added 38 mins ago
SA
Senior Forward Deployed Engineer
Sinch America Inc.
Denver, CO
- $155,000 to $186,000 USD / year
…outcomes. You are a production software engineer, customer solution architect, and technical delivery lead, accountable for making the customer solution work in…
Added 1 hour ago
Solutions Architect - Oracle Manufacturing Applications/Solumina MES, Hybrid/Remote
Sandia National Laboratories
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…Solutions department (Org 7577) is seeking an experienced Solutions Architect to join our collaborative team supporting IT solutions across Sandia's discrete manufacturing and lot-based…
Added 1 hour ago
SL
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Slalom, LLC
Denver, CO
- $142,000 to $173,500 USD / year
Added 1 hour ago
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Cloud Solution Architect - AI Apps
Microsoft
BC, CA · AB, CA
- $96,000 to $177,600 CAD / year
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Added 1 hour ago
API Architect
Avalore, LLC
Arlington, VA
…governance processes for API lifecycle management, and create developer documentation and examples to facilitate API adoption. This person will monitor API usage and performance metrics,…
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Cloud Engineer
Avalore, LLC
Arlington, VA
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Added 1 hour ago
Cybersecurity Architect
Avalore, LLC
Arlington, VA
The Cybersecurity Architect is responsible for embedding security into every layer of the War Data Platform by designing a comprehensive, defense-in-depth security architecture. This person…
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Data Architect
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Arlington, VA
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Enterprise Architect
Avalore, LLC
Arlington, VA
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Added 1 hour ago
Infrastructure Engineer
Avalore, LLC
Arlington, VA
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Solutions Architect
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Arlington, VA
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Platform Architect
Avalore, LLC
Arlington, VA
The Platform Architect is the primary internal-facing architect, responsible for the technical integrity, scalability, and reliability of the core WDP infrastructure itself. This person…
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Software Engineer
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Chantilly, VA
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Added 1 hour ago
Data Architect
Avalore, LLC
Chantilly, VA
The Data Architect will support the requirements for new system capabilities and enhancements for multiple applications in the customers' cloud computing environment.
Added 1 hour ago
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Cloud and AI Senior Partner Solution Architect
Microsoft
WA · GA · NC · CA · NJ · DC · Redmond, WA · Atlanta, GA · Raleigh, NC · San Francisco, CA · Edison, NJ · Washington, DC · Redmond · Atlanta · Raleigh · San Francisco · Edison · Washington
- $106,400 to $222,600 USD / year
…and organizations. As a Cloud and AI Senior Partner Solution Architect (PSA) for Software Development Companies (SDCs) within the Microsoft EPS CTO group, you play a pivotal role in…
Added 1 hour ago
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Principal Firmware Architect
Microsoft
WA · CA · TX · OR · NC · Redmond, WA · Mountain View, CA · Austin, TX · Hillsboro, OR · Raleigh, NC · Redmond · Mountain View · Austin · Hillsboro · Raleigh
- $142,800 to $304,200 USD / year
A firmware architect in the team is given the opportunity to both work with some of the most cutting edge silicon being produced, while shaping and designing the firmware on those platforms…
Added 1 hour ago
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Senior AI Engineer
Microsoft
WA · Redmond, WA · Redmond
- $119,800 to $261,000 USD / year
Architect, prototype, and lead the iteration on AI agent experiences that reimagine domain-specific workflows across Copilot in Office and Copilot Cowork, rapidly validating feasibility,…
Added 1 hour ago
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Sr. Cloud Solution Architect
Microsoft
United States
- $106,400 to $222,600 USD / year
Added 1 hour ago
Associate Director, Senior Service Designer (GenAI Experience)
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Cincinnati, OH
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Senior ServiceNow HRSD Architect / Expert
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Senior AI Engineer
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Senior Web Applications Engineer
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Senior Java Developer
Toyota
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AWS Certifications (Certified Developer – Associate/Certified DevOps Engineer – Professional/Certified Solutions Architect – Professional)

Senior Software Engineer - Lab Automation

United States

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.

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Job details

Pay: The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range.
Experience: 5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Posting language: English
Posted: Nov 4, 2026

Original job description

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organizations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximizing these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence to assist our scientists to deliver more innovative and transformative medicines for patients worldwide.

The Opportunity

At Genentech (gRED) and Roche (pRED), we’re applying software, robotics, and advanced AI to solve one of humanity’s hardest challenges: building fully autonomous, self-healing laboratories for lights-out drug discovery. Advances in AI, data, and computational sciences are transforming drug discovery and development. The Computational Sciences Center of Excellence (CoE) and the Data and Digital Catalyst (DDC) team are building the foundational platform for autonomous labs - turning frontier AI models, rich physical telemetry, and multi-vendor robotics into resilient, intelligent systems that run complex science unattended around the clock to deliver life-saving medicines to patients faster than ever before.

As a Senior Software Engineer – Lab Automation, you will be the essential bridge connecting software architecture, frontier AI models, and real-world physical instrumentation. You will architect the hardware abstraction layers, instrument integration frameworks, and orchestration engines that allow diverse lab automation platforms to operate with seamless reliability and closed-loop error recovery. If you are inspired by the challenge of building a robust software backbone powering autonomous science, this is your opportunity to pioneer the next generation of automated laboratories at global scale.

In this role, you will:

Design, program, and troubleshoot high-throughput lab workflows ensuring robust assay execution on physical hardware.
Build orchestration systems, hardware abstraction layers, and instrument drivers that manage retries, handle shared resource contention, and enable 24/7 unattended operation.
Implement telemetry, logging, metrics, and alerting across hardware and software to diagnose failures and resolve root causes using software hooks or vision models rather than relying on manual workarounds.
Build systems to maintain an accurate real-time digital representation of the lab, including sample tracking, instrument state, and reagent availability, with bidirectional integration into LIMS and ELNs.
Manage hardware requirements, site constraints, communication protocols, and workcell integration from initial mechanical layout and prototyping through production deployment.
Work directly with software engineers, automation scientists, and hardware engineers to translate complex scientific protocols into production-grade technical architectures.

Who you are

5+ years of software engineering and physical hardware integration experience, or an equivalent advanced degree with a proven industrial automation track record.
Proficient in Python or C# for building modular software architectures, integration frameworks, and distributed services.
Strong software engineering fundamentals, including system design, automated testing, version control, CI/CD, debugging, and production operations.
AI-native software engineer with effective practices for providing context, decomposing problems, directing agents, reviewing their work, and validating results. Deep understanding of the limitations of AI-generated code.
Hands-on experience programming commercial liquid-handling platforms and integrating robotic arms or manipulators into unified automated workcells.
Experienced in designing workflow orchestration and scheduling systems that manage shared resources, dynamic dependencies, and execution priorities.
Skilled at leveraging APIs and SDKs (such as REST, gRPC, and vendor interfaces) to interact with complex laboratory software ecosystems.
Practical rapid-prototyping design experience, including CAD, 3D printing, CNC milling, or laser cutting for custom fixtures and hardware adaptations.
Familiar with molecular biology, biochemistry, or wet-lab workflows, enabling effective translation between scientific requirements and engineering deliverables.
Clear communicator adept at collaborating across multidisciplinary teams spanning research scientists, software developers, and automation engineers.

Preferred, but not required

Experience creating and evaluating AI agents used within applications, including designing robust evals to measure agent performance and reliability.
Experience integrating computer vision models (such as OpenCV, YOLO, or SAM) for automated error recovery, deck inspection, and anomaly detection.
Hands-on background in training, evaluating, or adopting AI/ML models, including reinforcement learning or imitation learning for robotics.
Knowledgeable about sensors, microcontrollers, embedded communication protocols, and task-and-motion planning.
Familiar with cloud infrastructure, containerized deployment, and digital twin simulation workflows.

Relocation benefits are not available for this opportunity

The expected salary range for this position based on the primary location of San Francisco is $142,500 - 264,700 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

#ComputationCoE #tech4lifeComputationalScience

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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More about this job

Skills

Robotics
Troubleshoot
LIMS
Communication skills
Python
C#
Test automation
CI/CD
Debugging
Workflow
Scheduling
3D Printing
CNC
Operate laser cutting equipment
Molecular biology
Translation
Research
SAM
Inspection
ML

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