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Added 4 mins ago
Warehouse Lead Industrial Engineer - Ryder Last Mile (remote)
Ryder System
Salem, OR
…improvement methods to support new and existing operations. The Lead Engineer will identify, lead and drive change within the operation through data driven CI, Engineering, and Automation…
Added 18 mins ago
Senior Software Development Engineer in Test (SDET)
STERIS Corporation
Vernon Hills, IL
While the formal title is Senior Test Automation Engineer, this is fundamentally a Senior Software Development Engineer in Test (SDET) role that requires deep software development expertise…
Added 19 mins ago
BA
Systems Engineer
Butler America
Owego, NY
- $82 to $96 USD / hour
Added 19 mins ago
AI enabled Device Modeling Engineer
Global Foundries
Malta, NY
…a cross-functional technology-development environment. The engineer will work with device physicists, compact-modeling experts, characterization engineers, PDK developers, and circuit…
Added 19 mins ago
AI enabled PDK Development Engineer
Global Foundries
Malta, NY
GlobalFoundries is seeking an AI-Enabled PDK Development Engineer with strong artificial intelligence and software-engineering skills to develop, implement, test, and support AI-guided…
Added 20 mins ago
Sr. Manufacturing Test Engineer, Factory Launch
Tesla, Inc.
BUFFALO, NY
What to ExpectWe are seeking a Sr. Test Engineer for our Factory Launch Team to facilitate the deployment, sustaining, and improvement of automated manufacturing test systems developed…
Added 20 mins ago
MB
Senior Software Engineer - Salesforce, Java
M&T Bank
Buffalo, NY
- $97,100 to $161,800 USD / year
…level in at least one programming language, verified by a lead software engineer. Apply appropriate data structures and algorithms to solve business…
Added 20 mins ago
Warehouse Lead Industrial Engineer - Ryder Last Mile (remote)
Ryder System
Albany, NY
…improvement methods to support new and existing operations. The Lead Engineer will identify, lead and drive change within the operation through data driven CI, Engineering, and Automation…
Added 21 mins ago
VM
GEOINT Display Systems Engineer
Volt Management Corp
ROCHESTER, NY
- $45 to $47 USD / hour
Added 21 mins ago
Salesforce Developer
MetLife
New York, NY
The Sales Technology Developer is an early-career software and platform engineer who helps build, test, configure, and support Salesforce-based capabilities for the GB360 Sales scaled…
Added 21 mins ago
AE
Senior AI Engineer II - Forward Deployment - Enterprise AI Platforms
American Express
New York, NY
- $123,000 to $215,250 USD / year
As a Forward Deployed AI Engineer, you will partner closely with business units, product teams, and engineering organizations to identify and reframe high-value opportunities, translate…
Added 22 mins ago
Agentic Delivery Software Engineer III
Deloitte
Rochester, NY · Williamsville, NY · Jericho, NY · New York, NY
As a Software Engineer III on the Customer team, you will advance AI-assisted software delivery, AI agent development, and agentic system implementation by helping teams translate…
Added 22 mins ago
AE
Sr Mgr-Digital Product Mgmt
American Express
New York, NY
- $123,000 to $215,250 USD / year
This individual does not need to be a software engineer, but should have enough technical depth to work effectively with Engineering and Architecture teams and participate meaningfully in…
Added 22 mins ago
Machine Learning Engineer 5 (IC)
Capital One
New York, NY
Leverage continuous integration and continuous deployment best practices, including test automation and monitoring, to ensure successful deployment of ML models and application code
Added 22 mins ago
Senior Software Engineer
Maybern Solutions, Inc.
NEW YORK, NY
Added 22 mins ago
Software Development Senior Manager
Verizon Communications, Inc.
NEW YORK, NY
Added 22 mins ago
Senior Manager, Business Development
EPAM Systems
New York, NY
…technology solutions in Cloud, Digital, Big Data, Analytics, Core Software Engineering, Legacy Modernization, DevOps, Agile, Automation, and more; with specific knowledge of technology…
Added 27 mins ago
J
Senior Technical Support Engineer - Overnight Shift (PST)
Jobgether
Remote, United States
- $86,000 to $115,000 USD / year
…resolve complex enterprise support challenges across clinical software, integrations, and customer IT environments. You will take ownership of critical incidents, guide customers through…
Added 56 mins ago
Senior QA Automation / SDET
Marvik
Remote, United States
Join as a Software Engineer to build AI full-stack solutions and shape an engineering culture that values autonomy, creativity, and technical excellence. 🚀
Added 1 hour ago
Senior AI Delivery Engineer
Jobgether
Remote, United States
Working knowledge of APIs, authentication, data integration, scripting, low-code and pro-code automation, source control, and software testing practices.
Added 1 hour ago
Engineer- Controls III USA (1st Shift)
First Solar, Inc.
Gaffney, SC
…requirements. - Proven experience using Auto Desk AutoCad drafting software to create electrical schematic and panel layouts. - Excellent understanding/knowledge programming of Rockwell…
Added 1 hour ago
EC
Lead Programmatic Manufacturing Engineer, Switchboards
Eaton Corporation
Sumter, SC
- $97,000 to $143,000 USD / year
Eaton’s ARS division is currently seeking a Lead Programmatic Manufacturing Engineer, Switchboards.
Added 1 hour ago
Cloud DevSecOps Engineer
Serco USA
VA · Arlington, VA · Washington, DC · MD
We are seeking a Cloud DevSecOps Engineer to support the secure, reliable, and automated delivery of applications and infrastructure across Amazon Web Services (AWS) GovCloud and Commercial…
Added 1 hour ago
Lead Airborne Systems - Software Engineer IV
University Corporation for Atmospheric Research
Broomfield, CO
2026-10-30 About the Role UCAR is excited to announce the job opening for the Lead Airborne Systems - Software Engineer IV role at the Research Aviation Facility. This position is the…
Added 1 hour ago
Software Engineer
CACI International
Aurora, CO
Grow your software engineering career with meaningful impact as a Software Engineer working in the space domain!

Freenome

Senior Systems Integration Engineer

Brisbane, CA, United States

The US target range of our base salary for new hires is $156,750 - $200,025.

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Job details

Pay: The US target range of our base salary for new hires is $156,750 - $200,025.
Posting language: English
Posted: Oct 29, 2026

Original job description

About this opportunity:

Freenome is hiring a Senior Systems Integration Engineer to provide technical leadership and drive hands on contribution to the development of next generation NGS assays/products for early cancer detection. You will work in a Product Development team of world-class Scientists and Engineers focused on delivering Freenome’s IVD assay portfolio. If you are passionate about deploying the power of NGS-based diagnostics in clinical care, have a high sense of ownership, and take pride in providing technical leadership to a growing team of Systems Integration Engineers, while continuing to make an individual impact, we would love to speak with you!

As part of a dynamic, flexible company you will be adapting to rapid technological progress and change, and help the team building the platform do the same.The role reports to the Senior Manager, Systems Integration. This role will be an onsite role based in our Brisbane, California headquarters.

What you’ll do:

Lead Functional Integration strategy and execute end to end assay workflows, system verification and validation activities while maintaining a strong hands on role in automation platform operation and system level testing.
Independently define study scope, validation strategies, success criteria, and execution plans. Develop and execute system level protocols, analyze results against User Needs, Design Input Requirements and Product Requirements, and communicate conclusions to inform AV/CV and development exit readiness.
Partner with Development, SW Test Engineering, Automation, and SLIMS to align test coverage, entry and exit criteria, and deployment derisking strategies. Incorporate qualified software releases into Functional Integration and coordinate or execute lab deployment and fleet wide configuration verification.
Drive the System Reliability program and lead its cross functional core team. Establish reliability metrics, trend recurring failure modes, prioritize and triage risks, and coordinate mitigation follow through with accountable subsystem owners. Lead prioritized technical investigations and communicate improvement opportunities, mitigation status, and resource needs.
Evaluate system performance, proactively identify roadblocks, characterize root causes, and apply analytical problem solving skills to develop and execute scalable solutions for prioritized reagent, workflow, automation, hardware, software, and system integration issues.
Author and review system level requirements, test strategies, validation protocols, traceability documentation, technical reports, and other design control documentation within the Design Control framework and Design History Files.
Provide subject matter expertise to system level dFMEA, pFMEA, risk management, hazard assessment, and design review activities; identify hardware, firmware, software, workflow, and process mitigations with accountable subsystem owners to support adequate risk control measures.
Build cross functional buy in by clearly communicating opportunities, risks, needs, problems, proposed solutions, and results in the appropriate forums. Facilitate project debriefs to improve future integration and validation activities.
Provide technical guidance and mentorship to SI engineers in study design, hands on execution, troubleshooting, and documentation while maintaining individual ownership of assigned deliverables.

Must haves:

Bachelor’s degree with 8+ years of relevant work experience, Master’s degree with 6+ years of relevant work experience, or Doctoral degree with 3+ years of relevant work experience; or equivalent experience.
Education or equivalent experience in a relevant field such as Biology, Biochemistry, Bioengineering, Biomedical Engineering, Systems Engineering, Mechanical Engineering, Electrical Engineering, or a related discipline.
Direct experience developing, integrating, or evaluating NGS assays and/or NGS based diagnostics, including hands on experience with automated NGS workflows.
Experience driving hands on system integration activities, including assay workflow execution, automation platform operation, system evaluation, troubleshooting, performance characterization, and validation or verification testing.
Experience developing and executing system level test plans and protocols, including data analysis, interpretation of test results, assessment of requirements conformance, failure investigation, and root cause analysis.
Data analysis expertise and experience with various data analysis software packages, including well developed statistical analysis skills and design of experiments (DOE), using JMP, R, or equivalent tools. Knowledge of SQL, Python, R, or other programming languages is highly desired.
Experience analyzing reliability data, identifying recurring failure modes, and coordinating cross functional investigations and mitigation follow through.
Direct experience working in an FDA regulated, IVD, medical device, diagnostics, or other regulated product development environment.
Strong working knowledge of requirements management, design controls, risk management, traceability, technical report authoring, Design History Files, and applicable quality system requirements.
Demonstrated ability to operate independently on complex technical assignments, lead key projects, prioritize work based on company objectives and available resources, provide technical guidance to others, and build cross functional buy in.

Benefits and additional information:

The US target range of our base salary for new hires is $156,750 - $200,025. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information.

Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.

Applicants have rights under Federal Employment Laws.

Family & Medical Leave Act (FMLA)
Equal Employment Opportunity (EEO)
Employee Polygraph Protection Act (EPPA)

California applicants please review the CCPA Notice at Collection here:

California Consumer Privacy Act (CCPA)

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More about this job

Skills

Leadership
Team building
Product comprehension
Problem solving
Workflow
ICT system integration
Documentation
Risk management
Hazard assessment
Firmware
Troubleshooting
Biomedical engineering
Mechanical engineering
Electrical engineering
Data analysis
Root cause analysis
Statistics
R
SQL
Python
Programming languages

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