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Added 1 min ago
BP
Unit Manager - Security (Security Operations)
Bechtel Plant Machinery, Inc.
Monroeville, PA
- $119,000 to $174,500 USD / year
Added 9 mins ago
UA
Process Quality Specialist
USABB ABB Inc.
Richmond, VA
- $83,300 to $133,280 USD / year
Familiar with key industry standards such as UL1561, NEMA ST-20, IEEE C57.12.01, IEEE C57.12.91, DOE 2016, UL9540, UL1008S, UL1778, UL891 and CSA C22.2, which enhances compliance and…
Added 24 mins ago
Account Supervisor
Fact & Fiction
Kansas City, MO
Oversee a high-volume content program of agency-produced video and static, creator-developed, and UGC content, batched quarterly and built natively for each platform
Added 26 mins ago
Emergency Management Manager
Amentum
Washington, DC
Amentum is currently seeking an Emergency Management Manager to join our team in Alice Springs, Australia! The Emergency Management Manager is responsible for developing, implementing, and…
Added 43 mins ago
GM
EMS Adjunct Instructor
Global Medical Response, Inc.
St Louis, MO
- $30 to $35 USD / hour
Presents content for each course as mutually established with the Program Manager
Added 44 mins ago
Lead Project Manager, GS AI Integration (5749)
Honeywell
Kansas City, MO
Added 47 mins ago
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Project Engineer
Toyon
Goleta, CA
- $100,000 to $150,000 USD / year
The annual pay range for the Technical Program Manager position is $100,000 to $150,000.
Added 1 hour ago
Staff Manufacturing Engineer, General Assembly - Advanced ME
Rivian
Irvine, CA
Added 1 hour ago
Project Manager 2
Edgewater Federal Solutions, Inc.
Los Alamos, NM
Edgewater Federal Solutions is seeking a Project Manager 2 to support the ERP modernization efforts at a major national laboratory. This role operates under the guidance of the Program…
Added 1 hour ago
AC
Associate Planner
Ada County
Boise, ID
- $60,000 USD / year
…Completed work is subject to review and evaluation by the Planning Manager and the Department…
Added 1 hour ago
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Technical Program Manager
Toyon
Goleta, CA
- $165,000 to $220,000 USD / year
Toyon Research Corporation is seeking an experienced Technical Program Manager to handle multiple complex projects in the Flight Test and Evaluation Team in the Aerospace Division. This…
Added 1 hour ago
Program Manager
North Carolina Agriculture & Technical State Unive
Greensboro, NC
The Program Manager will support the Principal Investigator (PI), faculty technical leads, and senior personnel in managing project operations, recruiting and supervising research…
Added 1 hour ago
Program Manager - Energy
Munro Defense Inc
Auburn Hills, MI
The Program Manager – Energy will oversee multiple programs supporting energy infrastructure, facility modernization, and operational improvement initiatives. Based in Oak Ridge, Tennessee,…
Added 1 hour ago
Adoption and Pregnancy Support Case
CATHOLIC CHARITIES
MILWAUKEE, WI
Added 1 hour ago
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CDL Truck Driver - Residential Rearload Driver
WM
Kissimmee, FL
- $21 USD / hour
We Are Committed to Your Growth: Your Tomorrow Education Assistance Program, paid on-the-job training, and established career progression.
Added 2 hours ago
NY
PT Assistant Director Brooklyn 178K
NEW YORK EDGE, INC
Brooklyn, NY
- $25 to $30 USD / hour
…the overall administration of the New York Edge After-School Program under the supervision of the After-School Program Director, including but not limited to implementing enrichment…
Added 2 hours ago
IP
Supervisor
Independent Pet Partners
Lakewood, CO
- $15.16 to $17.63 USD / hour
Assist the Store Manager in overall management of store operations.
Added 2 hours ago
Practice Manager- Berkshire Veterinary Hospital
Rarebreed Hospital Support Jobs
Pittsfield, MA
Berkshire Veterinary Hospital is looking to add a compassionate and skilled Practice Manager to our team. Compassionate care and lasting relationships are at the heart of everything we do.…
Added 2 hours ago
Operations Support Specialist
Strategic Management Solutions, LLC.
Los Alamos, NM
Strategic Management Solutions, LLC (SMSI) provides expert management consulting, program and project management, and technical consulting services to government and private-sector clients.…
Added 3 hours ago
M(
HR Generalist
MAAC (Metropolitan Area Advisory Committee)
Chula Vista, CA
- $33.65 to $36.05 USD / hour
Hourly Range: $33.65 - $36.05 per hour (DOE / Q)
Added 3 hours ago
GM
EMS Adjunct Instructor
Global Medical Response, Inc.
Roseville, CA
- $30 to $35 USD / hour
Presents content for each course as mutually established with the Program Manager
Added 3 hours ago
Early Childhood Director (Ridgewood YMCA)
Queens, NY
safe and quality program, including, but not limited to, staff supervision,
Added 3 hours ago
Program Manager IV
General Atomics
San Diego, CA
…who can lead and manage a large-scale department of energy (DOE) program focused on the development of GA-EMS’ innovative silicon carbide ceramic matrix composite technology, SiGA®, for…
Added 3 hours ago
Manager, Faculty Development and College Curriculum
NIGHTINGALE EDUCATION LLC SOLE MB
Remote, United States
The Manager, Faculty and Curriculum Development is responsible for assessing faculty performance, facilitation, curriculum programs, evaluating course and program outcomes, and providing…
Added 3 hours ago
B
Operations Supervisor
BWXT
Jonesborough, TN
- $70,000 to $103,000 USD / year
Implements and maintains a cost-effective key performance indicator program.

Freenome

Senior Systems Integration Engineer

Brisbane, CA, United States

The US target range of our base salary for new hires is $156,750 - $200,025.

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Job details

Pay: The US target range of our base salary for new hires is $156,750 - $200,025.
Posting language: English
Posted: Oct 29, 2026

Original job description

About this opportunity:

Freenome is hiring a Senior Systems Integration Engineer to provide technical leadership and drive hands on contribution to the development of next generation NGS assays/products for early cancer detection. You will work in a Product Development team of world-class Scientists and Engineers focused on delivering Freenome’s IVD assay portfolio. If you are passionate about deploying the power of NGS-based diagnostics in clinical care, have a high sense of ownership, and take pride in providing technical leadership to a growing team of Systems Integration Engineers, while continuing to make an individual impact, we would love to speak with you!

As part of a dynamic, flexible company you will be adapting to rapid technological progress and change, and help the team building the platform do the same.The role reports to the Senior Manager, Systems Integration. This role will be an onsite role based in our Brisbane, California headquarters.

What you’ll do:

Lead Functional Integration strategy and execute end to end assay workflows, system verification and validation activities while maintaining a strong hands on role in automation platform operation and system level testing.
Independently define study scope, validation strategies, success criteria, and execution plans. Develop and execute system level protocols, analyze results against User Needs, Design Input Requirements and Product Requirements, and communicate conclusions to inform AV/CV and development exit readiness.
Partner with Development, SW Test Engineering, Automation, and SLIMS to align test coverage, entry and exit criteria, and deployment derisking strategies. Incorporate qualified software releases into Functional Integration and coordinate or execute lab deployment and fleet wide configuration verification.
Drive the System Reliability program and lead its cross functional core team. Establish reliability metrics, trend recurring failure modes, prioritize and triage risks, and coordinate mitigation follow through with accountable subsystem owners. Lead prioritized technical investigations and communicate improvement opportunities, mitigation status, and resource needs.
Evaluate system performance, proactively identify roadblocks, characterize root causes, and apply analytical problem solving skills to develop and execute scalable solutions for prioritized reagent, workflow, automation, hardware, software, and system integration issues.
Author and review system level requirements, test strategies, validation protocols, traceability documentation, technical reports, and other design control documentation within the Design Control framework and Design History Files.
Provide subject matter expertise to system level dFMEA, pFMEA, risk management, hazard assessment, and design review activities; identify hardware, firmware, software, workflow, and process mitigations with accountable subsystem owners to support adequate risk control measures.
Build cross functional buy in by clearly communicating opportunities, risks, needs, problems, proposed solutions, and results in the appropriate forums. Facilitate project debriefs to improve future integration and validation activities.
Provide technical guidance and mentorship to SI engineers in study design, hands on execution, troubleshooting, and documentation while maintaining individual ownership of assigned deliverables.

Must haves:

Bachelor’s degree with 8+ years of relevant work experience, Master’s degree with 6+ years of relevant work experience, or Doctoral degree with 3+ years of relevant work experience; or equivalent experience.
Education or equivalent experience in a relevant field such as Biology, Biochemistry, Bioengineering, Biomedical Engineering, Systems Engineering, Mechanical Engineering, Electrical Engineering, or a related discipline.
Direct experience developing, integrating, or evaluating NGS assays and/or NGS based diagnostics, including hands on experience with automated NGS workflows.
Experience driving hands on system integration activities, including assay workflow execution, automation platform operation, system evaluation, troubleshooting, performance characterization, and validation or verification testing.
Experience developing and executing system level test plans and protocols, including data analysis, interpretation of test results, assessment of requirements conformance, failure investigation, and root cause analysis.
Data analysis expertise and experience with various data analysis software packages, including well developed statistical analysis skills and design of experiments (DOE), using JMP, R, or equivalent tools. Knowledge of SQL, Python, R, or other programming languages is highly desired.
Experience analyzing reliability data, identifying recurring failure modes, and coordinating cross functional investigations and mitigation follow through.
Direct experience working in an FDA regulated, IVD, medical device, diagnostics, or other regulated product development environment.
Strong working knowledge of requirements management, design controls, risk management, traceability, technical report authoring, Design History Files, and applicable quality system requirements.
Demonstrated ability to operate independently on complex technical assignments, lead key projects, prioritize work based on company objectives and available resources, provide technical guidance to others, and build cross functional buy in.

Benefits and additional information:

The US target range of our base salary for new hires is $156,750 - $200,025. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information.

Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.

Applicants have rights under Federal Employment Laws.

Family & Medical Leave Act (FMLA)
Equal Employment Opportunity (EEO)
Employee Polygraph Protection Act (EPPA)

California applicants please review the CCPA Notice at Collection here:

California Consumer Privacy Act (CCPA)

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More about this job

Skills

Leadership
Team building
Product comprehension
Problem solving
Workflow
ICT system integration
Documentation
Risk management
Hazard assessment
Firmware
Troubleshooting
Biomedical engineering
Mechanical engineering
Electrical engineering
Data analysis
Root cause analysis
Statistics
R
SQL
Python
Programming languages

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