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Added 1 min ago
Submarine Acoustics Install Management Logistics Engineer, Senior
Booz Allen Hamilton_United States
Washington, DC
…the integrity of the mission. We’re looking for a logistics engineer like you to apply your engineering and process improvement expertise to develop tools for PMS401 within PAE Undersea.…
Added 1 min ago
Model-Based Systems Engineer
Booz Allen Hamilton_United States
Indian Head, MD
As a Model-Based Systems Engineer (MBSE) on our team, you’ll perform trade studies and risk assessments and have the chance to shape mission and system architecture development processes by…
Added 1 min ago
Lead Cybersecurity Automation Engineer
Synopsys
Austin, TX
…learning machines. We lead in chip design, verification, and IP integration, empowering the creation of high-performance silicon chips and software content. Join us to transform the future…
Added 2 mins ago
TT
Structural Project Engineer
Thornton Tomasetti
San Diego, CA
- $92,000 to $120,000 USD / year
…mission is to bring our clients' ideas to life and, in the process, lay the groundwork for a better, more resilient future. We provide support and opportunities to our employees to achieve…
Added 3 mins ago
Sr. Systems Engineer Autonomy
Rivian
Palo Alto, CA
Added 8 mins ago
Electrical Engineer
SAIC
Crane, IN
SAIC is seeking a motivated Electrical Engineer to join our team in Crane, IN, supporting critical defense electronic systems that directly impact mission readiness and warfighter…
Added 10 mins ago
Project Management, Senior Advisor to the Fleet Maintenance Officer (N43D)
Noblis
Norfolk, VA
Assist in driving strategic readiness initiatives including Ship Wartime Repair and Maintenance (SWaRM) and Naval Maintenance, Repair, and Overhaul (N-MRO) process improvements.
Added 13 mins ago
GH
Technical Support Engineer 2
GE HEALTHCARE
Remote, United States
- $108,000 to $162,000 USD / year
The Technical Support Engineer 2 (TSE II) drives customer satisfaction through Service Excellence by providing advanced technical support, implementation leadership, project participation,…
Added 13 mins ago
IC
Intel Foundry LTD Product Yield Development Engineer
Intel Corporation
OR · NM · TX · AZ
- $141,910 to $269,100 USD / year
Collaborate with Program Managers, Process Integration, Device Integration and Defect teams to identify yield detractors and yield enhancement opportunities.
Added 13 mins ago
IC
GPU Logic Design Engineer
Intel Corporation
CA
- $141,910 to $200,340 USD / year
As a GPU Logic Design Engineer at Intel, you will play a critical role in shaping the future of graphics and compute technologies. You will be part of a dynamic team driving innovation and…
Added 15 mins ago
Software Engineer, Employee Experience & Productivity
Apple
Culver City, CA
Studio & Production and Music operations. As a Software Engineer, you'll architect and
Added 18 mins ago
Software Development Engineer, EC2 UltraServer Availability
Amazon Data Services, Inc.
Seattle, WA
The Software Development Engineer II will design, build, and maintain cloud-based repair and recovery workflows for NVIDIA GB200 / GB300 UltraServers, orchestrating repair and recovery…
Added 18 mins ago
Senior Modem Engineer, Satellite Communication
Amazon Kuiper Manufacturing Enterprises LLC
San Diego, CA
· Collaborate with system architects on SoC subsystem integration, including IP block configuration, instantiation, and interface validation.
Added 18 mins ago
Director, Development Preconstruction & Cost Management
Quality Technology Services, LLC
United States
Added 18 mins ago
Systems Engineer, Associate, Experienced and Senior Level
The Boeing Company
Saint Charles, MO
Experience with systems development and integration
Added 18 mins ago
Optical Systems Engineer (Senior, Principal) - Millennium Space Systems
Millennium Space Systems
El Segundo, CA
An Optical Systems Engineer possesses a strong background in spaceborne electro-optical sensor technology (visible to infrared; active and passive). You will oversee optical systems on our…
Added 21 mins ago
Mechanical Engineering Manager
BlackSky
Tukwila, WA
…equipment. You will define and maintain an effective design process that strikes the right balance of rigor, technical performance, and risk to meet challenging program objectives and…
Added 22 mins ago
SAC Early Talent Interview Day
Barry-Wehmiller
Sacramento, CA
BW Design Group is a fully integrated architecture, engineering, construction, system integration, and consulting firm committed to helping our clients realize their most critical goals…
Added 22 mins ago
Software Engineer, ERP Applications & Development
Anduril Industries
Costa Mesa, CA
As a Software Engineer on ERP Technology, you will design, build, and maintain the internal tools, backend services, and APIs that extend what Fusion can do out of the box. You'll work…
Added 22 mins ago
Senior Technical Program Manager
Anduril Industries
Costa Mesa, CA
Anduril is seeking a Senior Technical Program Manager to lead the test, integration, and operational fielding of Group 3 uncrewed aircraft systems and their mission payloads. In this role…
Added 26 mins ago
Integrations Engineer – MuleSoft
Wynn Resorts
Las Vegas, NV
Wynn Las Vegas is seeking an Integrations Engineer to join our team. In this role, you will be responsible for designing, developing, and implementing integration solutions using Mulesoft…
Added 28 mins ago
Senior Principal Engineer, Physical Designer
MSI - (Marvell Semiconductor Inc.) US
Santa Clara, CA
…next-generation, high-performance processor chips in a leading-edge CMOS process technology, targeted at server, and networking…
Added 29 mins ago
T
Senior Process Engineer - Thin Film 1
TSMC
Camas, WA
- $91,220 to $124,664 USD / year
Understanding of principle of thin film process knowledge, and it is a plus for equipment knowledge and/or integration knowledge.
Added 29 mins ago
Contamination Control Engineer 1
United Launch Alliance
Cape Canaveral, FL
United Launch Alliance is seeking a proactive, effective, and innovative Contamination Control Engineer RS-1 to join our team at Cape Canaveral Space Force Station, FL. The successful…
Added 31 mins ago
Sr. Systems Engineering Tools and Process Assurance Manager
Aerospace
Phoenix, AZ
…need for a Sr. Engineering Manager to lead development and process assurance of systems engineering tools and processes. As the product development lifecycle becomes increasingly complete…

Freenome

Senior Systems Integration Engineer

Brisbane, CA, United States

The US target range of our base salary for new hires is $156,750 - $200,025.

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Job details

Pay: The US target range of our base salary for new hires is $156,750 - $200,025.
Posting language: English
Posted: Oct 29, 2026

Original job description

About this opportunity:

Freenome is hiring a Senior Systems Integration Engineer to provide technical leadership and drive hands on contribution to the development of next generation NGS assays/products for early cancer detection. You will work in a Product Development team of world-class Scientists and Engineers focused on delivering Freenome’s IVD assay portfolio. If you are passionate about deploying the power of NGS-based diagnostics in clinical care, have a high sense of ownership, and take pride in providing technical leadership to a growing team of Systems Integration Engineers, while continuing to make an individual impact, we would love to speak with you!

As part of a dynamic, flexible company you will be adapting to rapid technological progress and change, and help the team building the platform do the same.The role reports to the Senior Manager, Systems Integration. This role will be an onsite role based in our Brisbane, California headquarters.

What you’ll do:

Lead Functional Integration strategy and execute end to end assay workflows, system verification and validation activities while maintaining a strong hands on role in automation platform operation and system level testing.
Independently define study scope, validation strategies, success criteria, and execution plans. Develop and execute system level protocols, analyze results against User Needs, Design Input Requirements and Product Requirements, and communicate conclusions to inform AV/CV and development exit readiness.
Partner with Development, SW Test Engineering, Automation, and SLIMS to align test coverage, entry and exit criteria, and deployment derisking strategies. Incorporate qualified software releases into Functional Integration and coordinate or execute lab deployment and fleet wide configuration verification.
Drive the System Reliability program and lead its cross functional core team. Establish reliability metrics, trend recurring failure modes, prioritize and triage risks, and coordinate mitigation follow through with accountable subsystem owners. Lead prioritized technical investigations and communicate improvement opportunities, mitigation status, and resource needs.
Evaluate system performance, proactively identify roadblocks, characterize root causes, and apply analytical problem solving skills to develop and execute scalable solutions for prioritized reagent, workflow, automation, hardware, software, and system integration issues.
Author and review system level requirements, test strategies, validation protocols, traceability documentation, technical reports, and other design control documentation within the Design Control framework and Design History Files.
Provide subject matter expertise to system level dFMEA, pFMEA, risk management, hazard assessment, and design review activities; identify hardware, firmware, software, workflow, and process mitigations with accountable subsystem owners to support adequate risk control measures.
Build cross functional buy in by clearly communicating opportunities, risks, needs, problems, proposed solutions, and results in the appropriate forums. Facilitate project debriefs to improve future integration and validation activities.
Provide technical guidance and mentorship to SI engineers in study design, hands on execution, troubleshooting, and documentation while maintaining individual ownership of assigned deliverables.

Must haves:

Bachelor’s degree with 8+ years of relevant work experience, Master’s degree with 6+ years of relevant work experience, or Doctoral degree with 3+ years of relevant work experience; or equivalent experience.
Education or equivalent experience in a relevant field such as Biology, Biochemistry, Bioengineering, Biomedical Engineering, Systems Engineering, Mechanical Engineering, Electrical Engineering, or a related discipline.
Direct experience developing, integrating, or evaluating NGS assays and/or NGS based diagnostics, including hands on experience with automated NGS workflows.
Experience driving hands on system integration activities, including assay workflow execution, automation platform operation, system evaluation, troubleshooting, performance characterization, and validation or verification testing.
Experience developing and executing system level test plans and protocols, including data analysis, interpretation of test results, assessment of requirements conformance, failure investigation, and root cause analysis.
Data analysis expertise and experience with various data analysis software packages, including well developed statistical analysis skills and design of experiments (DOE), using JMP, R, or equivalent tools. Knowledge of SQL, Python, R, or other programming languages is highly desired.
Experience analyzing reliability data, identifying recurring failure modes, and coordinating cross functional investigations and mitigation follow through.
Direct experience working in an FDA regulated, IVD, medical device, diagnostics, or other regulated product development environment.
Strong working knowledge of requirements management, design controls, risk management, traceability, technical report authoring, Design History Files, and applicable quality system requirements.
Demonstrated ability to operate independently on complex technical assignments, lead key projects, prioritize work based on company objectives and available resources, provide technical guidance to others, and build cross functional buy in.

Benefits and additional information:

The US target range of our base salary for new hires is $156,750 - $200,025. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information.

Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.

Applicants have rights under Federal Employment Laws.

Family & Medical Leave Act (FMLA)
Equal Employment Opportunity (EEO)
Employee Polygraph Protection Act (EPPA)

California applicants please review the CCPA Notice at Collection here:

California Consumer Privacy Act (CCPA)

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More about this job

Skills

Leadership
Team building
Product comprehension
Problem solving
Workflow
ICT system integration
Documentation
Risk management
Hazard assessment
Firmware
Troubleshooting
Biomedical engineering
Mechanical engineering
Electrical engineering
Data analysis
Root cause analysis
Statistics
R
SQL
Python
Programming languages

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