Jobs in the United States

25+ jobs

Save this search

Added 1 min ago
Principal Opto-Mechanical Engineer
Alcon Research, LLC. Company
Lake Forest, CA
The Principal Opto-Mechanical Engineer is primarily responsible for leading teams in designing, validating, and optimizing optical components and systems. You will conduct advanced…
Added 1 min ago
Opto-Mechanical Engineer
Alcon Research, LLC. Company
Lake Forest, CA
We foster an inclusive culture and are looking for diverse, talented people to join Alcon. As an Opto-Mechanical Engineer supporting Surgical Instrumentation Research & Development, you…
Added 2 mins ago
Senior Data Engineer
Marvik
Remote, United States
Added 7 mins ago
J
Senior Engineer, Partner Integrations Platform
Jobgether
Remote, United States
- $145,000 to $160,000 USD / year
…applications and next steps. Our partner is looking for a Senior Engineer, Partner Integrations Platform based in the United…
Added 7 mins ago
Senior AI Delivery Engineer
Jobgether
Remote, United States
This position is listed on behalf of a partner company, who manages all applications and next steps. Our partner is looking for a Senior AI Delivery Engineer based in the United States.
Added 7 mins ago
Data Architecture & Data Engineering Leader
Jobgether
Remote, United States
Added 7 mins ago
BR
Spvr Terminal Operations - Temple, TX 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
BNSF Railway
Bakersfield, CA
- $113,000 USD / year
Designated Supervisor Locomotive Engineer (DSLE) certification preferred.
Added 7 mins ago
BR
Spvr Terminal Operations - Minot, ND
BNSF Railway
Minot, ND
- $113,000 USD / year
Designated Supervisor Locomotive Engineer (DSLE) certification preferred.
Added 9 mins ago
Manufacturing Engineer Co-op
RBC Bearings
Westminster, SC
Gain hands on Manufacturing Engineer experience in a cutting edge aerospace manufacturing environment in Westminster, SC.
Added 9 mins ago
Metallurgist II - Process
Nucor Steel Auburn, Inc.
Darlington, SC
This candidate will be expected to train into a rolling process engineer/metallurgical position or melt shop process/metallurgical engineering position.
Added 9 mins ago
Associate Manufacturing Engineer Trainee
RBC Bearings
Westminster, SC
The Associate Manufacturing Engineer plays a key role in supporting production operations by improving manufacturing processes, designing tooling and fixtures, troubleshooting production…
Added 9 mins ago
Application Engineer
Chart Industries
Richburg, SC
This Applications Engineer position functions as a primary technical resource for the field sales force and is responsible for actively driving and managing the technical and commercial…
Added 9 mins ago
Piping Superintendent - Simple Cycle - South Carolina Job Details | Black & Veatch Family of Companies
Black & Veatch
Beech Island, SC
Assists the Construction Engineer in the compilation of or answering Contractor Information Requests.
Added 9 mins ago
Engineer- Controls III USA (1st Shift)
First Solar, Inc.
Gaffney, SC
…database Responsible for maintaining and updating of manufacturing process tool electrical drawings globally, ensuring the tra king of equipment changes is documented and drawings are kept…
Added 9 mins ago
EC
Lead Programmatic Manufacturing Engineer, Switchboards
Eaton Corporation
Sumter, SC
- $97,000 to $143,000 USD / year
Eaton’s ARS division is currently seeking a Lead Programmatic Manufacturing Engineer, Switchboards.
Added 9 mins ago
Internal - Process Engineer - Final Finish
Continental Tire the Americas, LLC
Sumter, SC
Analyze workflows to identify improvement areas in the process
Added 9 mins ago
Internal - Technician IV (Maintenance Lead) – Tire Build
Continental Tire the Americas, LLC
Sumter, SC
Escalate technical issues to the lead engineer that cannot be resolved by the team after 2 hours of consecutive asset downtime
Added 9 mins ago
Flight Controls Mechanical Hydraulics Design & Analysis Engineer (Experienced or Senior)
The Boeing Company
North Charleston, SC
Boeing Commercial Airplanes is seeking a Flight Controls Mechanical Hydraulics Design & Analysis Engineer ( Experienced or Senior) to join our 787 Flight Controls Mechanical Hydraulics…
Added 9 mins ago
Systems Integrations Engineer (Mid-level or Senior)
The Boeing Company
North Charleston, SC
The Systems Integration Engineer will work with a dynamic and diverse Systems Integration team that supports the design, configuration, production, certification, and delivery of 787s. The…
Added 9 mins ago
Electrical Wire Design Engineer (Associate or Experienced)
The Boeing Company
North Charleston, SC
…organization has an exciting opportunity for an Electrical Wire Design Engineer (Associate or Experienced) in North Charleston, SC. The positions will help us define the future 787…
Added 9 mins ago
Structures & Payload Design Engineer (Structural Design)
The Boeing Company
North Charleston, SC
…Airplanes South Carolina Design Center, as a Structures Design…
Added 9 mins ago
Principal Engineer Nuclear Systems - Plant Operations
GE Vernova
Greenville, SC
As Principal Engineer and Controlled Title Holder (CTH) for our Nuclear Plant Controls Services business, your mandate is to assure that our disparate controls disciplines coalesce into a…
Added 9 mins ago
Lead Core Repair Engineer
GE Vernova
Greenville, SC
…Service Onshore and Offshore Wind Turbines. The Lead Repair Engineer will develop repair procedures and tooling required to enable key repair capabilities for Service NPI. This includes…
Added 9 mins ago
Software Engineer - Product (Technical Leadership)
Meta
Columbia, SC
Software Engineer - Product (Technical Leadership) Responsibilities:
Added 9 mins ago
Senior Platform Engineer - NBA
Humana
Columbia, SC
The Senior Platform Engineer keeps the entire NBA platform healthy, reliable, and maintainable for the long term. You develop a working understanding of every layer of the technology stack…

Freenome

Senior Systems Integration Engineer

Brisbane, CA, United States

The US target range of our base salary for new hires is $156,750 - $200,025.

Apply About employer

Applications open in a new tab.

Job details

Pay: The US target range of our base salary for new hires is $156,750 - $200,025.
Posting language: English
Posted: Oct 29, 2026

Original job description

About this opportunity:

Freenome is hiring a Senior Systems Integration Engineer to provide technical leadership and drive hands on contribution to the development of next generation NGS assays/products for early cancer detection. You will work in a Product Development team of world-class Scientists and Engineers focused on delivering Freenome’s IVD assay portfolio. If you are passionate about deploying the power of NGS-based diagnostics in clinical care, have a high sense of ownership, and take pride in providing technical leadership to a growing team of Systems Integration Engineers, while continuing to make an individual impact, we would love to speak with you!

As part of a dynamic, flexible company you will be adapting to rapid technological progress and change, and help the team building the platform do the same.The role reports to the Senior Manager, Systems Integration. This role will be an onsite role based in our Brisbane, California headquarters.

What you’ll do:

Lead Functional Integration strategy and execute end to end assay workflows, system verification and validation activities while maintaining a strong hands on role in automation platform operation and system level testing.
Independently define study scope, validation strategies, success criteria, and execution plans. Develop and execute system level protocols, analyze results against User Needs, Design Input Requirements and Product Requirements, and communicate conclusions to inform AV/CV and development exit readiness.
Partner with Development, SW Test Engineering, Automation, and SLIMS to align test coverage, entry and exit criteria, and deployment derisking strategies. Incorporate qualified software releases into Functional Integration and coordinate or execute lab deployment and fleet wide configuration verification.
Drive the System Reliability program and lead its cross functional core team. Establish reliability metrics, trend recurring failure modes, prioritize and triage risks, and coordinate mitigation follow through with accountable subsystem owners. Lead prioritized technical investigations and communicate improvement opportunities, mitigation status, and resource needs.
Evaluate system performance, proactively identify roadblocks, characterize root causes, and apply analytical problem solving skills to develop and execute scalable solutions for prioritized reagent, workflow, automation, hardware, software, and system integration issues.
Author and review system level requirements, test strategies, validation protocols, traceability documentation, technical reports, and other design control documentation within the Design Control framework and Design History Files.
Provide subject matter expertise to system level dFMEA, pFMEA, risk management, hazard assessment, and design review activities; identify hardware, firmware, software, workflow, and process mitigations with accountable subsystem owners to support adequate risk control measures.
Build cross functional buy in by clearly communicating opportunities, risks, needs, problems, proposed solutions, and results in the appropriate forums. Facilitate project debriefs to improve future integration and validation activities.
Provide technical guidance and mentorship to SI engineers in study design, hands on execution, troubleshooting, and documentation while maintaining individual ownership of assigned deliverables.

Must haves:

Bachelor’s degree with 8+ years of relevant work experience, Master’s degree with 6+ years of relevant work experience, or Doctoral degree with 3+ years of relevant work experience; or equivalent experience.
Education or equivalent experience in a relevant field such as Biology, Biochemistry, Bioengineering, Biomedical Engineering, Systems Engineering, Mechanical Engineering, Electrical Engineering, or a related discipline.
Direct experience developing, integrating, or evaluating NGS assays and/or NGS based diagnostics, including hands on experience with automated NGS workflows.
Experience driving hands on system integration activities, including assay workflow execution, automation platform operation, system evaluation, troubleshooting, performance characterization, and validation or verification testing.
Experience developing and executing system level test plans and protocols, including data analysis, interpretation of test results, assessment of requirements conformance, failure investigation, and root cause analysis.
Data analysis expertise and experience with various data analysis software packages, including well developed statistical analysis skills and design of experiments (DOE), using JMP, R, or equivalent tools. Knowledge of SQL, Python, R, or other programming languages is highly desired.
Experience analyzing reliability data, identifying recurring failure modes, and coordinating cross functional investigations and mitigation follow through.
Direct experience working in an FDA regulated, IVD, medical device, diagnostics, or other regulated product development environment.
Strong working knowledge of requirements management, design controls, risk management, traceability, technical report authoring, Design History Files, and applicable quality system requirements.
Demonstrated ability to operate independently on complex technical assignments, lead key projects, prioritize work based on company objectives and available resources, provide technical guidance to others, and build cross functional buy in.

Benefits and additional information:

The US target range of our base salary for new hires is $156,750 - $200,025. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information.

Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.

Applicants have rights under Federal Employment Laws.

Family & Medical Leave Act (FMLA)
Equal Employment Opportunity (EEO)
Employee Polygraph Protection Act (EPPA)

California applicants please review the CCPA Notice at Collection here:

California Consumer Privacy Act (CCPA)

Apply About employer

More about this job

Skills

Leadership
Team building
Product comprehension
Problem solving
Workflow
ICT system integration
Documentation
Risk management
Hazard assessment
Firmware
Troubleshooting
Biomedical engineering
Mechanical engineering
Electrical engineering
Data analysis
Root cause analysis
Statistics
R
SQL
Python
Programming languages

Report this job