Jobs in the United States

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Added 3 hours ago
Senior NPI Hardware Quality Engineer
NVIDIA Corporation
North District, IL
12+ years of experience in the Hardware design development or testing arena or as Process Engineer.
Added 3 hours ago
Senior Hardware Quality Engineer
NVIDIA Corporation
North District, IL
12+ years of experience in the Hardware design development or testing arena or as Process Engineer.
Added 3 hours ago
Senior Power Engineer
NVIDIA Corporation
North District, IL
Our team in Yokneam, Israel is looking for a Senior Power Integrity Engineer to join the Hardware Board Design team and lead PI development of next-generation Network Adapters for…
Added 3 hours ago
Software Engineer, SPE
NVIDIA Corporation
North District, IL
NVIDIA Networking System Product Engineering group is looking for an excellent Software Engineer. The position requires an understanding of HW and SW to provide stable, efficient, smoothly…
Added 3 hours ago
System Software Engineer
NVIDIA Corporation
North District, IL
NVIDIA Networking System Product Engineering group is looking for an excellent Software Engineer. The position requires an understanding of HW and SW to provide stable, efficient, smoothly…
Added 4 hours ago
HIL Functional Test Engineer
Deloitte US
Los Angeles, CA
The test engineer will run manual and automated hardware-in-the-loop functional and regression testing of AV fleets for meeting spaces. This covers Crestron and Q-SYS control logic and…
Added 4 hours ago
Manufacturing Engineer I- Electronics
Collins Aerospace
Melbourne, FL
We are growing and adding a Manufacturing Electrical Engineering position supporting our product lines in the Melbourne FL facility. As a Manufacturing Electrical Engineer I, you will make…
Added 7 hours ago
MECHANICAL ENGINEER
Naval Sea Systems Command
Newport News, VA
Added 20 hours ago
NS
Staff Applications Engineer (Integrated Voltage Regulators)
NAVITAS SEMICONDUCTOR USA, INC.
Torrance, CA
- $145,000 to $185,000 USD / year
We are seeking an Applications Engineer - Integrated Voltage Regulators to join the IVR Business Unit and own the system-level performance of integrated voltage regulators from the lab…
Added 20 hours ago
NS
Staff Product Engineer (Integrated Voltage Regulators)
NAVITAS SEMICONDUCTOR USA, INC.
Torrance, CA
- $145,000 to $185,000 USD / year
We are seeking a Staff Product Engineer - Integrated Voltage Regulators to join the IVR Business Unit and own device characterization and datasheet development from first silicon through…
Added 21 hours ago
Associate Engineer Electrical
Northrop Grumman
Gilbert, AZ
Our Space Systems Division Integration and Test group is seeking an Associate Engineer Electrical (Level 1) to join our team of qualified and diverse individuals in Gilbert, AZ. You will…
Added 1 day ago
High Speed Systems Engineer
Leidos
Beavercreek, OH
Leidos Defense Systems is seeking a highly motivated Systems Engineer who loves collaboration and being a part of something big, to join our team. This role drives the implementation of…
Added 1 day ago
Lead Modules Field Engineer
Bechtel Corporation
New Albany, OH
The Area Lead Modules Field Engineer (ALMFE) serves as the primary field engineering lead responsible for the successful receipt, assembly, installation, testing, and turnover of modules in…
Added 1 day ago
A
Electrical Instrumentation Engineer
Actalent
Houston, TX
- $75 to $85 USD / hour
Strong understanding of electrical design and construction practices.
Added 1 day ago
Senior Cybersecurity Engineer (Center of Excellence)
GE Vernova
Melbourne, FL
Lead the cybersecurity workstream on Tier 1 projects end to end: requirements review, security architecture, detailed design, build, configuration, FAT, SAT, commissioning and handover.
Added 1 day ago
Senior Instrumentation and Controls Design Engineer
Trustees of Princeton University
Princeton, NJ
Added 1 day ago
High Speed Systems Engineer
Leidos
King Of Prussia, PA
Leidos Defense Systems is seeking a highly motivated Systems Engineer who loves collaboration and being a part of something big, to join our team. This role drives the implementation of…
Added 1 day ago
High Speed Systems Engineer
Leidos
Arlington, VA
Leidos Defense Systems is seeking a highly motivated Systems Engineer who loves collaboration and being a part of something big, to join our team. This role drives the implementation of…
Added 1 day ago
MS
Senior Business Development Engineer (BDE), US Army
Motorola Solutions, Inc.
Denver, CO
- $40,123 USD / year
Lead the technical planning, network configuration, and live-on-the-air execution of field trials, modernizations, and user evaluations in conjunction with the BD and Applications…
Added 1 day ago
Software Engineer, Industrial Controls
Aalo Atomics
Austin, TX
We're hiring a Software Engineer, Industrial Controls to lead the architecture and implementation of Aalo's software-defined industrial controls runtime for energy and industrial process…
Added 1 day ago
Test & Evaluation Hardware Design Engineer (Experienced & Senior)
The Boeing Company
Long Beach, CA
As a Hardware Engineer in BT&E, you will play a pivotal role in the design and development of lab hardware and sustainment of new and legacy units. In addition, you will document…
Added 1 day ago
Senior Mechatronics Engineer
J&J Family of Companies
Santa Clara, CA
The Senior Mechatronics Engineer will lead the design, development, integration, verification, and lifecycle support of complex systems and equipment in a regulated MedTech environment. The…
Added 1 day ago
High Speed Systems Engineer
Leidos
San Diego, CA
Leidos Defense Systems is seeking a highly motivated Systems Engineer who loves collaboration and being a part of something big, to join our team. This role drives the implementation of…
Added 1 day ago
HIL Functional Test Engineer
Deloitte
Los Angeles, CA
The test engineer will run manual and automated hardware-in-the-loop functional and regression testing of AV fleets for meeting spaces. This covers Crestron and Q-SYS control logic and…
Added 1 day ago
NAVAL ARCHITECT (STABILITY)
U.S. Pacific Fleet
San Diego, CA
You will lead and serve as a member of the Configuration Control Board and, along with other members of the board, maintain certification of SWRMC Docking Facilities.

Freenome

Senior Systems Integration Engineer

Brisbane, CA, United States

The US target range of our base salary for new hires is $156,750 - $200,025.

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Job details

Pay: The US target range of our base salary for new hires is $156,750 - $200,025.
Posting language: English
Posted: Oct 29, 2026

Original job description

About this opportunity:

Freenome is hiring a Senior Systems Integration Engineer to provide technical leadership and drive hands on contribution to the development of next generation NGS assays/products for early cancer detection. You will work in a Product Development team of world-class Scientists and Engineers focused on delivering Freenome’s IVD assay portfolio. If you are passionate about deploying the power of NGS-based diagnostics in clinical care, have a high sense of ownership, and take pride in providing technical leadership to a growing team of Systems Integration Engineers, while continuing to make an individual impact, we would love to speak with you!

As part of a dynamic, flexible company you will be adapting to rapid technological progress and change, and help the team building the platform do the same.The role reports to the Senior Manager, Systems Integration. This role will be an onsite role based in our Brisbane, California headquarters.

What you’ll do:

Lead Functional Integration strategy and execute end to end assay workflows, system verification and validation activities while maintaining a strong hands on role in automation platform operation and system level testing.
Independently define study scope, validation strategies, success criteria, and execution plans. Develop and execute system level protocols, analyze results against User Needs, Design Input Requirements and Product Requirements, and communicate conclusions to inform AV/CV and development exit readiness.
Partner with Development, SW Test Engineering, Automation, and SLIMS to align test coverage, entry and exit criteria, and deployment derisking strategies. Incorporate qualified software releases into Functional Integration and coordinate or execute lab deployment and fleet wide configuration verification.
Drive the System Reliability program and lead its cross functional core team. Establish reliability metrics, trend recurring failure modes, prioritize and triage risks, and coordinate mitigation follow through with accountable subsystem owners. Lead prioritized technical investigations and communicate improvement opportunities, mitigation status, and resource needs.
Evaluate system performance, proactively identify roadblocks, characterize root causes, and apply analytical problem solving skills to develop and execute scalable solutions for prioritized reagent, workflow, automation, hardware, software, and system integration issues.
Author and review system level requirements, test strategies, validation protocols, traceability documentation, technical reports, and other design control documentation within the Design Control framework and Design History Files.
Provide subject matter expertise to system level dFMEA, pFMEA, risk management, hazard assessment, and design review activities; identify hardware, firmware, software, workflow, and process mitigations with accountable subsystem owners to support adequate risk control measures.
Build cross functional buy in by clearly communicating opportunities, risks, needs, problems, proposed solutions, and results in the appropriate forums. Facilitate project debriefs to improve future integration and validation activities.
Provide technical guidance and mentorship to SI engineers in study design, hands on execution, troubleshooting, and documentation while maintaining individual ownership of assigned deliverables.

Must haves:

Bachelor’s degree with 8+ years of relevant work experience, Master’s degree with 6+ years of relevant work experience, or Doctoral degree with 3+ years of relevant work experience; or equivalent experience.
Education or equivalent experience in a relevant field such as Biology, Biochemistry, Bioengineering, Biomedical Engineering, Systems Engineering, Mechanical Engineering, Electrical Engineering, or a related discipline.
Direct experience developing, integrating, or evaluating NGS assays and/or NGS based diagnostics, including hands on experience with automated NGS workflows.
Experience driving hands on system integration activities, including assay workflow execution, automation platform operation, system evaluation, troubleshooting, performance characterization, and validation or verification testing.
Experience developing and executing system level test plans and protocols, including data analysis, interpretation of test results, assessment of requirements conformance, failure investigation, and root cause analysis.
Data analysis expertise and experience with various data analysis software packages, including well developed statistical analysis skills and design of experiments (DOE), using JMP, R, or equivalent tools. Knowledge of SQL, Python, R, or other programming languages is highly desired.
Experience analyzing reliability data, identifying recurring failure modes, and coordinating cross functional investigations and mitigation follow through.
Direct experience working in an FDA regulated, IVD, medical device, diagnostics, or other regulated product development environment.
Strong working knowledge of requirements management, design controls, risk management, traceability, technical report authoring, Design History Files, and applicable quality system requirements.
Demonstrated ability to operate independently on complex technical assignments, lead key projects, prioritize work based on company objectives and available resources, provide technical guidance to others, and build cross functional buy in.

Benefits and additional information:

The US target range of our base salary for new hires is $156,750 - $200,025. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information.

Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.

Applicants have rights under Federal Employment Laws.

Family & Medical Leave Act (FMLA)
Equal Employment Opportunity (EEO)
Employee Polygraph Protection Act (EPPA)

California applicants please review the CCPA Notice at Collection here:

California Consumer Privacy Act (CCPA)

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More about this job

Skills

Leadership
Team building
Product comprehension
Problem solving
Workflow
ICT system integration
Documentation
Risk management
Hazard assessment
Firmware
Troubleshooting
Biomedical engineering
Mechanical engineering
Electrical engineering
Data analysis
Root cause analysis
Statistics
R
SQL
Python
Programming languages

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