Embryologist I

ABOUT eGENESIS

eGenesis is a clinical-stage biotechnology company developing human-compatible engineered organs to address the severe global organ shortage. The Company’s proprietary genome engineering platform enables extensive, multiplex gene edits to remove key biological barriers, add protective human transgenes, and inactivate endogenous retroviruses. EGEN-2784, a genetically engineered porcine kidney, is the Company’s lead program and is currently being evaluated in a multi-patient Expanded Access study at MGH. eGenesis is headquartered in Cambridge, MA.

At eGenesis, our core values - innovation, collaboration, compassion, resilience, and passion - are at the center of how we work. We engineer hope and bring passion to everything we do. We collaborate and learn from one another, combining diverse expertise to tackle complex challenges. We innovate boldly, pushing boundaries and science to new heights. where no pig organ has gone before. With resilience, we navigate challenges and celebrate progress together. And in all we do, we lead with compassion - for our patients, our people, and our pigs.

POSITION SUMMARY

The Embryologist I provides critical embryology support for GMP production within the GMP production facility. This position reports to the Associate Director of GMP Production. The Embryologist will operate in strict accordance with company Standard Operating Procedures (SOPs), GMP facility protocols, and regulatory agency guidelines to advance the company’s core mission. This position requires adherence to strict biosecurity protocols, including showering-in to the animal facility to perform designated tasks.

PRIMARY RESPONSIBILITIES

• Execute GMP laboratory activities and function in strict compliance with eGenesis standard operating procedures.
• Perform and assist with daily laboratory processes, including porcine oocyte handling and evaluation from LOPU donors, as well as embryo handling for embryo transfers.
• Adhere to SOPs and maintain the highest quality standards during the execution of daily laboratory duties.
• Operate, monitor, and maintain all equipment necessary to perform designated laboratory tasks.
• Provide general operational support and laboratory upkeep, including inventory management of media, reagents, solutions, and aliquots.
• Support core eGenesis programs, focusing primarily on in vitro porcine embryo production.
• Partner with the supervisor to develop, update, and maintain reports regarding laboratory processes and experimental results.
• Accurate and timely documentation of GMP records within an electronic laboratory notebook.
• Document laboratory processes, equipment operations, and staff training compliance for new laboratory protocols.
• Promote and maintain a safe, compliant workplace environment.
• Follow safe work practices and enforce health and safety regulations. Proactively report unsafe acts or conditions, ensure equipment is properly maintained, and report all accidents/incidents. Inspect designated work areas and execute remedial actions to minimize or eliminate hazards. Complete all required training assignments, forms, and administrative paperwork.
• Perform other duties and assume other responsibilities as assigned.

BASIC QUALIFICATIONS

• B.S. in Animal Science or a related scientific discipline.
• 0-1+ years of relevant experience in an in vitro embryo production laboratory within an academic or industry setting.
• Knowledge of pig embryology is beneficial but not required.
• Working knowledge of standard laboratory equipment.
• Proficiency in MS Office (MS Excel in particular).
• Strong time management skills with a demonstrated ability to prioritize workflows.
• High attention to detail and strong problem-solving capabilities.
• Excellent written and verbal communication skills.
• Strong organizational skills with the ability to multi-task effectively.

PHYSICAL DEMANDS

While performing the duties of this job, the employee is regularly required to work in different environments, including farm, shop, office, and animal husbandry environments in varying weather conditions. The employee frequently is required to be walking, stooping, climbing, and crouching. Employees are regularly expected to lift objects 30-60lbs multiple times throughout the day. Specific vision abilities required by this job include close vision, distance vision, color vision, peripheral vision, depth perception and ability to adjust to focus.

WORK ENVIRONMENT

This job operates in multiple environments, including office, laboratory, surgery, necropsy, and animal husbandry environment. This role routinely uses standard office equipment such as computers, phones, copy machines, filing cabinets, and fax machines. This job may require the use of hazardous chemicals, conduct sample collection on livestock and operate in a dusty environment.

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