Jobs in the United States

25+ jobs

Save this search

Added 8 mins ago
Associate Director - Chemicals Consulting
S&P Global
Houston, TX
As an Associate Director in Chemicals Consulting, you will lead complex client engagements and help shape the growth of our global advisory business. You will combine deep chemicals…
Added 11 mins ago
Retail Interior Design Sales Leader
Ethan Allen Global, Inc.
Oak Brook, IL
…leading interior design destination combining state-of-the-art technology with personal service. After more than 90 profitable years in business, we still make about 75% of our…
Added 19 mins ago
UO
CIRES / NOAA Global Systems Laboratory, Post Doctoral Associate in Numerical Wea
University of Colorado Denver
Boulder, CO
- $65,000 to $70,000 USD / year
…weather and air quality models, state-of-the-science decision support tools and visualization systems and use high-performance computing technology to support a Weather-Ready Nation. GSL…
Added 19 mins ago
M
Retail Support Associate - Shoe Expeditor, Culver City Center - Full Time
Macy's
Culver City, CA
- Full-time
This entails regularly using technology to update product prices, promotions, and information on products and fixtures in accordance with company guidelines and policies.
Added 19 mins ago
M
Retail Commission Sales Associate - Fine Jewelry, Anderson Town Center - Full Time
Macy's
Cincinnati, OH
- Full-time
…the role include promoting our loyalty and warranty programs, support inventory and fulfillment activities, and supporting special events. You also will ensure the security, accuracy, and…
Added 19 mins ago
M
At Your Service Center Associate, La Cumbre Plaza - Part Time
Macy's
Santa Barbara, CA
- Part-time
…delivering a seamless and personalized shopping experience. You’ll support all At Your Service activities, including Buy Online Pickup In Store (BOPS), merchandise returns, order pickups,…
Added 19 mins ago
M
Retail Selling Support Associate - Womens Clothing, Short Pump Town Center - Part Time
Macy's
Richmond, VA
- Part-time
As a Macy’s Women's Clothing Selling Support colleague, you’ll help customers express their personal style and turn fashion into a source of inspiration. With a passion for hospitality, an…
Added 19 mins ago
M
At Your Service Center Associate, Victoria Gardens - Part Time
Macy's
Rancho Cucamonga, CA
- Part-time
…delivering a seamless and personalized shopping experience. You’ll support all At Your Service activities, including Buy Online Pickup In Store (BOPS), merchandise returns, order pickups,…
Added 20 mins ago
Seasonal Retail Commission Sales Associate - Fine Jewelry, South Park
Macy's
San Antonio, TX
…the role include promoting our loyalty and warranty programs, support inventory and fulfillment activities, and supporting special events. You also will ensure the security, accuracy, and…
Added 20 mins ago
Seasonal Retail Commission Sales Associate - Fine Jewelry, Visalia
Macy's
Visalia, CA
…the role include promoting our loyalty and warranty programs, support inventory and fulfillment activities, and supporting special events. You also will ensure the security, accuracy, and…
Added 20 mins ago
Seasonal Retail Fragrances Sales Associate, Dayton Mall
Macy's
Dayton, OH
As a Seasonal Fragrance Sales Support colleague, you'll play a key role in creating a warm, inviting experience in our fragrance department. You’ll help maintain a beautifully merchandised,…
Added 20 mins ago
Seasonal Fulfillment and Receiving Support Associate, Chapel Hills
Macy's
Colorado Springs, CO
This role goes far beyond just being a behind-the-scenes support colleague. Here, the customer is at the heart of everything we do - every day, all day. If you're passionate about selling,…
Added 20 mins ago
Seasonal Fulfillment and Receiving Support Associate, Galleria at Crystal Run
Macy's
Middletown, NY
This role goes far beyond just being a behind-the-scenes support colleague. Here, the customer is at the heart of everything we do - every day, all day. If you're passionate about selling,…
Added 20 mins ago
M
Retail Selling Support Associate - Womens Clothing, Falls - Part Time
Macy's
Miami, FL
- Part-time
As a Macy’s Women's Clothing Selling Support colleague, you’ll help customers express their personal style and turn fashion into a source of inspiration. With a passion for hospitality, an…
Added 20 mins ago
M
Retail Commission Sales Associate - Fine Jewelry, Market Place - Part Time
Macy's
Champaign, IL
- Part-time
…the role include promoting our loyalty and warranty programs, support inventory and fulfillment activities, and supporting special events. You also will ensure the security, accuracy, and…
Added 20 mins ago
Seasonal Fulfillment and Receiving Support Associate, Louis Joliet
Macy's
Joliet, IL
This role goes far beyond just being a behind-the-scenes support colleague. Here, the customer is at the heart of everything we do - every day, all day. If you're passionate about selling,…
Added 20 mins ago
Seasonal Retail At Your Service Associate, Pearlridge
Macy's
Aiea, HI
…delivering a seamless and personalized shopping experience. You’ll support all At Your Service activities, including Buy Online Pickup In Store (BOPS), merchandise returns, order pickups,…
Added 20 mins ago
Seasonal Retail Commission Sales Associate - Fine Jewelry, Northshore
Macy's
Peabody, MA
…the role include promoting our loyalty and warranty programs, support inventory and fulfillment activities, and supporting special events. You also will ensure the security, accuracy, and…
Added 20 mins ago
Seasonal Fulfillment and Receiving Support Associate, Roseville Galleria
Macy's
Roseville, CA
This role goes far beyond just being a behind-the-scenes support colleague. Here, the customer is at the heart of everything we do - every day, all day. If you're passionate about selling,…
Added 20 mins ago
M
At Your Service Center Associate, Willowbrook Mall - TX - Part Time
Macy's
Houston, TX
- Part-time
…delivering a seamless and personalized shopping experience. You’ll support all At Your Service activities, including Buy Online Pickup In Store (BOPS), merchandise returns, order pickups,…
Added 22 mins ago
Registrar
Fayetteville State University
NC
20% Technology and Data Support: The Registrar must have extensive knowledge of future-forward practices related to the work of a registrar for the purposes of compiling student statistical…
Added 24 mins ago
G
Associate Attorney - Civil Litigation Defense
GPAC
Kansas City, KS
- $90,000 to $110,000 USD / year
Experienced support staff and technology resources
Added 48 mins ago
Growth Associate
Encord
San Francisco, CA
We're looking for our first Growth Associate in SF. This is an opportunity to support across Encord's entire growth function: from our billboards or campaigns on X, to our AI leaders…
Added 48 mins ago
Growth Associate
Encord
New York City, NY
We've just launched our NYC office, and are looking for our first Growth Associate to join the team. This is an opportunity to support across Encord's entire growth function: from our…
Added 48 mins ago
VO
Veterinary Assistant ER
Vicar Operating, Inc. dba VCA
Clackamas, OR
- $21 to $29 USD / hour
Benefits: VCA offers a comprehensive benefits package to support the health, well-being, and professional development of its associates.

Dyne Therapeutics

Associate Director, Oligonucleotide Development

Waltham, MA, United States

$159,000 - $200,000 USD

Apply About employer

Applications open in a new tab.

Job details

Pay: $159,000 - $200,000 USD
Experience: 8+ years of relevant pharmaceutical or biotechnology industry experience, or an equivalent combination of education and experience.
Posting language: English
Posted: Aug 27, 2026

Original job description

Company Overview:

Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as preclinical programs for facioscapulohumeral muscular dystrophy (FSHD), Pompe disease and multiple DMD mutations. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook.

Role Summary

The Associate Director, Oligonucleotide Development leads chemical synthesis and development strategies for PMO and modified ASO payload molecules, overseeing execution internally and through external CDMOs. This role provides technical leadership across preclinical process and analytical development through technology transfer and GMP manufacturing for IND-enabling studies.

The Associate Director ensures the development of robust, scalable, and cost-effective manufacturing processes and serves as a key technical lead with external manufacturing partners. The role contributes to CMC strategy for preclinical and clinical-stage programs and supports global regulatory filings, including authoring and reviewing relevant Module 3 content.

This role is based in Waltham, MA and is not eligible for remote work. Physical presence onsite is expected 5 days per week.

Primary Responsibilities include:

Oligonucleotide Process & Analytical Development

Lead process development, optimization, and scale-up strategies for PMO and modified ASO payload molecules to support preclinical and clinical supply.
Provide technical leadership for oligonucleotide synthesis, purification, characterization, and associated manufacturing processes.
Support analytical development strategies, including impurity control, raw material specifications, and physicochemical characterization of oligonucleotide payloads and conjugated drug substances.
Identify and implement technologies and process improvements that enhance product quality, scalability, manufacturing robustness, and efficiency.
Prepare technical source documents, scientific presentations, and other development documentation.

External Manufacturing & Technology Transfer

Serve as a key technical lead for CDMOs responsible for oligonucleotide process development and manufacturing.
Lead technology transfer of manufacturing processes and analytical methods to external partners, ensuring effective execution, knowledge transfer, and data integrity.
Provide technical oversight of external development and manufacturing activities to ensure alignment with program timelines, quality expectations, and CMC objectives.
Lead investigation and resolution of complex process, manufacturing, and analytical challenges using scientifically rigorous and data-driven approaches.

CMC, Regulatory & GMP Execution

Contribute to CMC strategies supporting the advancement of preclinical and clinical-stage programs.
Author and review relevant CMC and product-related documentation for global regulatory submissions, including INDs and IMPDs.
Review and approve development and cGMP documentation, including technology transfer protocols, process characterization documents, Master Batch Records, and campaign summary reports.
Partner cross-functionally with Analytical Development, Quality, Regulatory, Manufacturing, and other CMC functions to ensure development and manufacturing activities support program objectives.

Experience and Skills Requirements:

Bachelor’s degree in Biochemistry, Chemical Engineering, Chemistry, Pharmaceutical Sciences, or a related scientific discipline; advanced degree preferred.
8+ years of relevant pharmaceutical or biotechnology industry experience, or an equivalent combination of education and experience.
Demonstrated expertise in the process chemistry and development of PMO and/or modified ASO oligonucleotides, including synthesis, purification, and scale-up.
Experience supporting pharmaceutical development programs, preferably within a clinical-stage biotechnology or pharmaceutical organization.
Demonstrated experience providing technical oversight of CDMOs and leading technology transfer activities.
Strong understanding of analytical development principles, including impurity control strategies, raw material specifications, and physicochemical characterization.
Experience contributing to CMC regulatory submissions, including INDs, IMPDs, or comparable global filings.
Working knowledge of cGMP requirements and development-stage manufacturing documentation.
Strong scientific judgment and problem-solving skills with the ability to assess technical risk, establish priorities, and drive solutions in a rapidly evolving development environment.
Demonstrated ability to influence and collaborate effectively across cross-functional teams and with external partners.

MA Pay Range

$159,000 - $200,000 USD

The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills.

The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.

Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.

Apply About employer

More about this job

Skills

Leadership
Good manufacturing practices
Manufacturing processes
Presentation skills
Documentation
Chemical engineering
Biotechnology
Problem solving

Report this job