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Civil Structural Engineer
GPAC
Norcross, GA
…design of commercial, industrial, institutional, and public infrastructure projects. You'll work alongside experienced professionals who are committed to mentorship, innovation, and…
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Civil Structural Engineer
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Chicago, IL
…design of commercial, industrial, institutional, and public infrastructure projects. You'll work alongside experienced professionals who are committed to mentorship, innovation, and…
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Senior Bridge Engineer
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…geotechnical consulting services for environmental, industrial and infrastructure construction projects. Headquartered in Austin, TX, Atlas currently has over 3,500 employees with offices…
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Director, Electrical Engineering
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…America. This role provides design leadership for electrical infrastructure across high-voltage (26 kV to 230 kV), medium-voltage (5 kV to 13.8 kV), and low-voltage systems, including…
Added 1 min ago
Infrastructure Engineer II
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SUMMARY: The Infrastructure Engineer II role is responsible for the operations of secure and highly available computing platforms, servers, and networks. This role is responsible for…
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Senior Software Engineer (Institutional, Financing)
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As a Senior Software Engineer on the Financing Engineering team within the Institutional group, you'll design, build, and scale the systems that safely manage billions of dollars in loans…
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Associate Software Engineer
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Infrastructure Engineer I
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Jackson, MS
Job Description: SUMMARY: The Infrastructure Engineer I role is responsible for the operations of secure and highly available computing platforms, servers, and networks. This role is…
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Senior Telecom Engineer
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Maximus is seeking an experienced Senior Telecom Engineer to lead the design, implementation, and optimization of Genesys Cloud solutions. This role is responsible for executing large-scale…
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Mechanical Engineer, Data Center Operations Engineering
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Network Operations Engineer
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Jackson, MS
Meta is seeking a Network Operations Engineer to join our Edge and Network Services (ENS) Foundation NetOps team. In this role, you will utilize your knowledge in hyperscale data center…
Added 6 mins ago
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Professional Engineer 1 (Civil/Transportation) NYHELPS
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- $102,406 to $127,439 USD / year
…contract claims and evaluate reimbursements for damage to its infrastructure through thorough and equitable analyses. Experience interacting with various offices and regions is helpful and…
Added 11 mins ago
Senior / Staff Software Engineer
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New York, NY
This is a hands-on senior individual-contributor role at the intersection of applied AI, product, and distributed systems. The role holder will take ambiguous customer problems and complex…
Added 14 mins ago
Software Product Engineer
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San Francisco · San Francisco, CA
Premier Global Links LLC is seeking an experienced Product Engineer for an innovative AI and engineering technology company in San Francisco. This role is ideal for a hands-on full-stack…
Added 15 mins ago
Senior AI Engineer, Marketing
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OPSWAT, a global leader in IT, OT, and ICS critical infrastructure cybersecurity, delivers an end-to-end platform that gives public and private sector organizations and enterprises the…
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Senior AI Engineer, Marketing
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Tampa, FL
OPSWAT, a global leader in IT, OT, and ICS critical infrastructure cybersecurity, delivers an end-to-end platform that gives public and private sector organizations and enterprises the…
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Entry Environmental Engineer - Water Services (2027 New Grads!)
CDM Smith
Chattanooga, TN
In this role, you will support the design and implementation of water and wastewater treatment facilities, sewer systems, pipelines, and related infrastructure. Under direct supervision,…
Added 15 mins ago
Junior Environmental Engineer - Water Services
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Fairfax, VA
…implementation of water and wastewater treatment facilities, sewer systems, pipelines, and associated infrastructure. You will work alongside experienced engineers and our Regional Lead…
Added 17 mins ago
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2027 Summer Internship (US) - Software/AI Engineer (Handheld Mobile Computers)
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- $33 to $40.5 USD / hour
Autonomous Agentic Systems: Architect LLM-powered agents to automate workflow parsing, extract system insights from unstructured data, and auto-validate developer API integrations.
Added 17 mins ago
Engineer Transmission and Distribution Planning
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MONSEY, NY
Under general supervision, the Engineer will support Engineering Planning to enhance the distribution and transmission systems ensuring safe and reliable power delivery. Responsibilities…
Added 17 mins ago
Engineer Systems Technician
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Niagara Falls., NY
Added 18 mins ago
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Lead Network Engineer
RWE Americas
White Plains, NY
- $127,000 to $171,000 USD / year
The Lead Network Engineer provides advanced technical leadership for the design, implementation, operation, and security of OT network infrastructure across multiple sites and geographies.
Added 19 mins ago
Full Stack Software Engineer, Level II
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BUFFALO, NY
…distributes mission software for fielded electromagnetic warfare systems, including the AN/APR-39 radar warning receiver family, the AN/APR-48A/B Modernized Radar Frequency Interferometer,…
Added 19 mins ago
Senior Software Engineer (Institutional, Financing)
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Albany, NY
As a Senior Software Engineer on the Financing Engineering team within the Institutional group, you'll design, build, and scale the systems that safely manage billions of dollars in loans…
Added 19 mins ago
Associate Software Engineer
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This job is an integral member of an agile software engineer team responsible for building scalable software applications across all digital channels to serve our customers. Responsible for…

CURIA

Principal Engineer

United States

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Job details

Experience: Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Posting language: English
Posted: Nov 4, 2026

Original job description

Principal Engineer – Filling & Lyophilization – United States Build your future at Curia, where our work has the power to save lives. The Principal Engineer will lead equipment engineering for large capital projects in sterile filling and lyophilization to support Curia’s strategic growth. This includes leading network-wide capital execution to expand, modernize, and standardize manufacturing infrastructure. The incumbent will direct the specification, procurement, installation, commissioning, and qualification of advanced aseptic technologies to increase capacity, efficiency, and compliance for drug product programs. This position interfaces with Curia’s network manufacturing sites, client technical teams, and global leadership. The role provides technical oversight, mentorship, and engineering guidance across site-based teams and major capital project teams. Curia is a global contract development and manufacturing organization (CDMO) with over 30 years of experience partnering with pharmaceutical and biotech companies to provide life-saving treatments to patients. At Curia, we are on a mission to advance our customers’ therapies from curiosity to cure and ultimately to improve patients’ lives. We proudly offer

Generous benefit options (eligible first day of employment)
Paid training, vacation and holidays (vacation accrual begins on first day of employment)
Career advancement opportunities
Education reimbursement
401K program with matching contributions
Learning platform
And more!

Responsibilities

Capital Project Execution: Lead filling and lyophilization equipment engineering for major capital projects ($10M–$50M+) from conceptual design through Commissioning, Qualification, and Validation (CQV)
Technical Transfer & Client Support: Drive robust, on-time technical transfers of API and Drug Product (DP) programs, partnering with the Global Program Management Office and site technical operation teams to satisfy client expectations
Equipment Specification & Procurement: Author User Requirement Specifications (URS), drive vendor selection, conduct capital cost estimation, and lead Factory/Site Acceptance Testing (FAT/SAT) for primary equipment (fill lines, isolators, lyos, VHP, capping)
Network Capability & Talent Development: Mentor site-based engineering teams across the Curia network, sharing best practices, upgrading skill sets, and driving technical standardization
Operational Excellence & Continuous Improvement: Partner with sites to troubleshoot complex equipment deviations, increase OEE, reduce cycle times, and execute cost-improvement programs
Vendor & Engineering Firm Management: Oversee external engineering design firms, equipment vendors, and field contractors for filling and lyophilization installations
Regulatory Compliance: Ensure all equipment and system designs comply with cGMP, EU Annex 1 (Contamination Control Strategy), FDA guidance, and global regulatory standards
This job has no direct supervisory responsibilities; serves as a technical lead and matrix manager for project teams and site engineering resources
Travel Requirement: Up to 40% travel, including international travel to plant sites and vendor facilities Education and Experience
Education: BS in Mechanical, Chemical, Electrical, or Biomedical Engineering (or related discipline)
Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Capital Projects: Proven track record leading major capital equipment execution projects exceeding $10M Technical Expertise: Advanced expertise in
Aseptic processing, high-speed sterile filling (vials, syringes, cartridges), and barrier technology (Isolators/RABS)
Lyophilization processes and automated loading/unloading systems (ALUS)
Decontamination systems (VHP / Hydrogen Peroxide Vapor)
Sterilization processes (SIP, Autoclaves, Depyrogenation Tunnels)
Critical Utilities (WFI, Clean Steam, Clean Compressed Air, Process Gases, Cleanrooms, and HVAC)
Commissioning, Qualification, and Validation (CQV / ISPE Baseline Guide approach)
Regulatory & Quality Knowledge: Deep understanding of global pharmaceutical regulations (FDA cGMP, EMA, EU Annex 1, PIC/S) Skills & Capabilities
Analytical & Problem Solving: Demonstrated root-cause analysis skills (e.g., FMEA, 6-Sigma) to address complex process and equipment deviations
Communication & Stakeholder Management: Excellent verbal and written communication skills with experience presenting technical concepts to executive leadership, site teams, and external clients
Computer & Software Skills: Proficient in project management software, CAD systems, CMMS, Trackwise/QMS systems, MS Office Suite (Word, Excel, PowerPoint), and process automation systems (PLC/SCADA/DCS) Other Qualifications & Requirements
Must pass a background check and drug screen
Ability to work in cleanroom environments (Gowning required) Physical Demands & Work Environment
Physical Demands: Regularly required to talk, hear, sit, stand, walk, reach, and lift up to 25–50 lbs
Work Environment: Mix of office environment, active construction sites, and cGMP cleanrooms. Moderate noise level with exposure to moving mechanical parts and industrial chemical/utility systems This job description in no way states or implies that these are the only duties to be performed by the employee(s) incumbent in this position. Employees will be required to follow any other job-related instructions and to perform any other job-related duties requested by any person authorized to give instructions or assignments. All duties and responsibilities are essential functions and requirements and are subject to possible modification to reasonably accommodate individuals with disabilities. To perform this job successfully, the incumbents will possess the skills, aptitudes, and abilities to perform each duty proficiently. Some requirements may exclude individuals who pose a direct threat or significant risk to the health or safety of themselves or others. The requirements listed in this document are the minimum levels of knowledge, skills, or abilities. This document does not create an employment contract, implied or otherwise, other than an “at will” relationship.

Salary range:$120,200-$144,100/year Education, experience, location and tenure may be considered along with internal equity when job offers are extended. We do not accept unsolicited assistance from any headhunters or recruitment firms for any of our job openings. All resumes or profiles submitted by search firms to any employee at Curia, in any form without a valid, signed search agreement by an authorized signatory in place for the specific position, approved by Talent Acquisition, will be deemed the sole property of Curia. No fee will be paid in the event the candidate is hired by Curia because of the unsolicited referral.

All interested applicants must apply online. Please be aware of scammers. Curia will only send offer letters and requests for sensitive personal information from a curiaglobal.com email address. Curia is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Curia is an E-Verify employer.

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More about this job

Skills

Procurement
Regulatory compliance
Program management
Microsoft Office
Estimating
Process improvement
Troubleshoot
Biomedical engineering
Pharmaceutical technology
SIP
HVAC
Pharmaceutical legislation
Problem solving
Root cause analysis
Communication skills
Stakeholder management
Project management
CMMS
Microsoft Word
Microsoft Excel
Microsoft PowerPoint
PLC
SCADA
DCS
Heavy lifting

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