Jobs in the United States

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Added 3 mins ago
Data Engineer, Analytics (Technical Leadership)
Meta
Oklahoma City, OK
Conceptualize and own the data architecture for multiple large-scale projects, while evaluating design and operational cost-benefit tradeoffs within systems
Added 3 mins ago
Senior Combustion Systems Engineer
OGE Energy Corp.
Oklahoma City, OK
Bachelors Degree in Engineering or PE & 5 years directly related engineering experience (which may include non-Engineer exp such as Engineering Internship, Design, Drafting, and Engineering…
Added 3 mins ago
AT
Machine Learning Senior Software Engineer
Akamai Technologies, Inc.
Oklahoma City, OK
- $121,400 to $218,600 USD / year
The Akamai Inference Cloud (AIC) team is part of Akamai's Cloud Technology Group. We design and operate AI platforms enabling customers to run models with unmatched performance, compliance,…
Added 3 mins ago
Software Engineer, Machine Learning RecSys
Meta
Oklahoma City, OK
Software Engineer, Machine Learning RecSys Responsibilities:
Added 3 mins ago
C
AI Data Engineer
Cognizant
Oklahoma City, OK
- $100,000 to $115,000 USD / year
As an AI Data Engineer, you will make an impact by designing, building, and optimizing scalable cloud-native data engineering solutions that enable advanced AI-driven applications and…
Added 3 mins ago
Supplier Support Manufacturing Engineer
GE Aerospace
Oklahoma City, OK · Shawnee, OK
As the Supplier Support Manufacturing Engineer, you will play a pivotal role in upholding GE Aerospace’s commitment to Safety, Quality, Delivery, and Cost (SQDC) while ensuring delivery…
Added 3 mins ago
Building Mechanical Engineer
Jacobs
Tulsa, OK · Oklahoma City, OK
We are looking for a driven Building Mechanical engineer to join our team for some of the most exciting infrastructure projects in the West Central region. You will join a core group of…
Added 3 mins ago
C
AI Data Engineer
Cognizant
Oklahoma City, OK
- $100,000 to $115,000 USD / year
As an AI Data Engineer, you will make an impact by designing, building, and optimizing scalable cloud-native data engineering solutions that enable advanced AI-driven applications and…
Added 3 mins ago
EG
Databricks Data Engineer
Eliassen Group
Oklahoma City, OK
- $150,000 to $154,000 USD / year
Our client seeks a Databricks Data Engineer to design, build, and maintain scalable, reliable, and secure data pipelines, infrastructure, and systems that support consulting services and…
Added 14 mins ago
Advanced Manufacturing Engineer Lead - P
FAITH TECHNOLOGIES INC
MENASHA, WI
Added 14 mins ago
Manufacturing Engineer
KOCH INDUSTRIES INC
PHILLIPS, WI
Added 14 mins ago
Cyber Security Infrastructure Engineer
APEX SYSTEMS INC
SUN PRAIRIE, WI
Added 14 mins ago
Mechanical Engineer
GLOBAL FINISHINGS SOLUTIONS
OSSEO, WI
Added 15 mins ago
Sr Project Engineer - Data Center Suppli
REHLKO
SHEBOYGAN, WI
Added 15 mins ago
Quality Engineer
WEASLER ENGINEERING
WEST BEND, WI
Added 15 mins ago
Corporate Quality Engineer
AMCOR FLEXIBLES NORTH AMERICA INC
OSHKOSH, WI
Added 15 mins ago
Automation Engineer II
Milwaukee Tool
Menomonee Falls, WI
…Automation Group (TAG), you will develop innovative automated test systems that support new product development across North America and our global laboratories. You will work…
Added 15 mins ago
Supplier Support Manufacturing Engineer
GE Aerospace
Waukesha, WI
As the Supplier Support Manufacturing Engineer, you will play a pivotal role in upholding GE Aerospace’s commitment to Safety, Quality, Delivery, and Cost (SQDC) while ensuring delivery…
Added 15 mins ago
Data Engineer, Analytics (Technical Leadership)
Meta
Madison, WI
Conceptualize and own the data architecture for multiple large-scale projects, while evaluating design and operational cost-benefit tradeoffs within systems
Added 15 mins ago
AT
Machine Learning Senior Software Engineer
Akamai Technologies, Inc.
Madison, WI
- $121,400 to $218,600 USD / year
The Akamai Inference Cloud (AIC) team is part of Akamai's Cloud Technology Group. We design and operate AI platforms enabling customers to run models with unmatched performance, compliance,…
Added 15 mins ago
Software Engineer, Machine Learning RecSys
Meta
Madison, WI
Software Engineer, Machine Learning RecSys Responsibilities:
Added 15 mins ago
C
AI Data Engineer
Cognizant
Madison, WI
- $100,000 to $115,000 USD / year
As an AI Data Engineer, you will make an impact by designing, building, and optimizing scalable cloud-native data engineering solutions that enable advanced AI-driven applications and…
Added 15 mins ago
C
AI Data Engineer
Cognizant
Madison, WI
- $100,000 to $115,000 USD / year
As an AI Data Engineer, you will make an impact by designing, building, and optimizing scalable cloud-native data engineering solutions that enable advanced AI-driven applications and…
Added 16 mins ago
Electrical Design Engineer
nVent
Madison, WI
As an Electrical Design Engineer at nVent Management Company, you will be a crucial technical resource responsible for the accuracy, quality, and intent of electrical project documentation.…
Added 16 mins ago
Electronic Test Technician II
TRAFFIC AND PARKING CONTROL CO INC
MILWAUKEE, WI

CURIA

Principal Engineer

United States

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Job details

Experience: Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Posting language: English
Posted: Nov 4, 2026

Original job description

Principal Engineer – Filling & Lyophilization – United States Build your future at Curia, where our work has the power to save lives. The Principal Engineer will lead equipment engineering for large capital projects in sterile filling and lyophilization to support Curia’s strategic growth. This includes leading network-wide capital execution to expand, modernize, and standardize manufacturing infrastructure. The incumbent will direct the specification, procurement, installation, commissioning, and qualification of advanced aseptic technologies to increase capacity, efficiency, and compliance for drug product programs. This position interfaces with Curia’s network manufacturing sites, client technical teams, and global leadership. The role provides technical oversight, mentorship, and engineering guidance across site-based teams and major capital project teams. Curia is a global contract development and manufacturing organization (CDMO) with over 30 years of experience partnering with pharmaceutical and biotech companies to provide life-saving treatments to patients. At Curia, we are on a mission to advance our customers’ therapies from curiosity to cure and ultimately to improve patients’ lives. We proudly offer

Generous benefit options (eligible first day of employment)
Paid training, vacation and holidays (vacation accrual begins on first day of employment)
Career advancement opportunities
Education reimbursement
401K program with matching contributions
Learning platform
And more!

Responsibilities

Capital Project Execution: Lead filling and lyophilization equipment engineering for major capital projects ($10M–$50M+) from conceptual design through Commissioning, Qualification, and Validation (CQV)
Technical Transfer & Client Support: Drive robust, on-time technical transfers of API and Drug Product (DP) programs, partnering with the Global Program Management Office and site technical operation teams to satisfy client expectations
Equipment Specification & Procurement: Author User Requirement Specifications (URS), drive vendor selection, conduct capital cost estimation, and lead Factory/Site Acceptance Testing (FAT/SAT) for primary equipment (fill lines, isolators, lyos, VHP, capping)
Network Capability & Talent Development: Mentor site-based engineering teams across the Curia network, sharing best practices, upgrading skill sets, and driving technical standardization
Operational Excellence & Continuous Improvement: Partner with sites to troubleshoot complex equipment deviations, increase OEE, reduce cycle times, and execute cost-improvement programs
Vendor & Engineering Firm Management: Oversee external engineering design firms, equipment vendors, and field contractors for filling and lyophilization installations
Regulatory Compliance: Ensure all equipment and system designs comply with cGMP, EU Annex 1 (Contamination Control Strategy), FDA guidance, and global regulatory standards
This job has no direct supervisory responsibilities; serves as a technical lead and matrix manager for project teams and site engineering resources
Travel Requirement: Up to 40% travel, including international travel to plant sites and vendor facilities Education and Experience
Education: BS in Mechanical, Chemical, Electrical, or Biomedical Engineering (or related discipline)
Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Capital Projects: Proven track record leading major capital equipment execution projects exceeding $10M Technical Expertise: Advanced expertise in
Aseptic processing, high-speed sterile filling (vials, syringes, cartridges), and barrier technology (Isolators/RABS)
Lyophilization processes and automated loading/unloading systems (ALUS)
Decontamination systems (VHP / Hydrogen Peroxide Vapor)
Sterilization processes (SIP, Autoclaves, Depyrogenation Tunnels)
Critical Utilities (WFI, Clean Steam, Clean Compressed Air, Process Gases, Cleanrooms, and HVAC)
Commissioning, Qualification, and Validation (CQV / ISPE Baseline Guide approach)
Regulatory & Quality Knowledge: Deep understanding of global pharmaceutical regulations (FDA cGMP, EMA, EU Annex 1, PIC/S) Skills & Capabilities
Analytical & Problem Solving: Demonstrated root-cause analysis skills (e.g., FMEA, 6-Sigma) to address complex process and equipment deviations
Communication & Stakeholder Management: Excellent verbal and written communication skills with experience presenting technical concepts to executive leadership, site teams, and external clients
Computer & Software Skills: Proficient in project management software, CAD systems, CMMS, Trackwise/QMS systems, MS Office Suite (Word, Excel, PowerPoint), and process automation systems (PLC/SCADA/DCS) Other Qualifications & Requirements
Must pass a background check and drug screen
Ability to work in cleanroom environments (Gowning required) Physical Demands & Work Environment
Physical Demands: Regularly required to talk, hear, sit, stand, walk, reach, and lift up to 25–50 lbs
Work Environment: Mix of office environment, active construction sites, and cGMP cleanrooms. Moderate noise level with exposure to moving mechanical parts and industrial chemical/utility systems This job description in no way states or implies that these are the only duties to be performed by the employee(s) incumbent in this position. Employees will be required to follow any other job-related instructions and to perform any other job-related duties requested by any person authorized to give instructions or assignments. All duties and responsibilities are essential functions and requirements and are subject to possible modification to reasonably accommodate individuals with disabilities. To perform this job successfully, the incumbents will possess the skills, aptitudes, and abilities to perform each duty proficiently. Some requirements may exclude individuals who pose a direct threat or significant risk to the health or safety of themselves or others. The requirements listed in this document are the minimum levels of knowledge, skills, or abilities. This document does not create an employment contract, implied or otherwise, other than an “at will” relationship.

Salary range:$120,200-$144,100/year Education, experience, location and tenure may be considered along with internal equity when job offers are extended. We do not accept unsolicited assistance from any headhunters or recruitment firms for any of our job openings. All resumes or profiles submitted by search firms to any employee at Curia, in any form without a valid, signed search agreement by an authorized signatory in place for the specific position, approved by Talent Acquisition, will be deemed the sole property of Curia. No fee will be paid in the event the candidate is hired by Curia because of the unsolicited referral.

All interested applicants must apply online. Please be aware of scammers. Curia will only send offer letters and requests for sensitive personal information from a curiaglobal.com email address. Curia is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Curia is an E-Verify employer.

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More about this job

Skills

Procurement
Regulatory compliance
Program management
Microsoft Office
Estimating
Process improvement
Troubleshoot
Biomedical engineering
Pharmaceutical technology
SIP
HVAC
Pharmaceutical legislation
Problem solving
Root cause analysis
Communication skills
Stakeholder management
Project management
CMMS
Microsoft Word
Microsoft Excel
Microsoft PowerPoint
PLC
SCADA
DCS
Heavy lifting

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