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Cost Engineer
Flatiron Construction Corp
Havre De Grace, MD
- $100,000 USD / year
Assists in or performs generation of project budget and monthly forecasting within Company supported cost control software.
Added 1 min ago
Electrical Engineer - Power Distribution
CEL - Critical Power
Williamsburg, VA
Develop complete electrical schematic drawings using EPLAN or equivalent software (AutoCAD Electrical), to the required accuracy and documentation standard.
Added 1 min ago
Engineer I
Victaulic Company
Easton, PA
Product Development, Corporate Engineering | Victaulic – Easton, PA
Added 2 mins ago
Supplier Quality Engineering Co-Op
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ZOLL Medical is a growing, innovation-driven company on the forefront of delivering medical devices to save lives, and software solutions to improve efficiency. With customers in more than…
Added 2 mins ago
CNC Machinist
Borg Design, Inc.
Hudson, MA
- Read and interpret engineering drawings, blueprints, and work instructions
Added 2 mins ago
G
Civil Engineer - Land Development/Design
GPAC
Aurora, CO
- $115,000 to $145,000 USD / year
…sanitary sewer plans using AutoCAD Civil 3D and a variety of other engineering…
Added 3 mins ago
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Commercial PM/Drywall Estimator
GPAC
Indianapolis, IN
- $90,000 to $120,000 USD / year
Proficient in project management software and Microsoft Office Suite.
Added 4 mins ago
Transportation Engineer
GPAC
Norcross, GA
…providers, contractors, public agencies, and multidisciplinary engineering teams to deliver safe, efficient, code-compliant roadway…
Added 5 mins ago
Software Engineer
CoreLogic Solutions, LLC
Dallas, TX
Design, develop, test, deploy, and maintain scalable software applications following established engineering standards, coding best practices, and architectural guidelines under general…
Added 6 mins ago
Materials Co-op Engineer/Intern (Fall 2027)
Applied Medical Technology Inc.
Brecksville, OH
· Major Fields: Chemical Engineering, Polymer Engineering, Materials Engineering, Chemistry, or any related field
Added 8 mins ago
Civil Structural Engineer
GPAC
Norcross, GA
Perform structural analysis using industry-standard engineering software.
Added 8 mins ago
Transportation Engineer
GPAC
Chicago, IL
…providers, contractors, public agencies, and multidisciplinary engineering teams to deliver safe, efficient, code-compliant roadway…
Added 8 mins ago
Civil Structural Engineer
GPAC
Chicago, IL
Perform structural analysis using industry-standard engineering software.
Added 9 mins ago
BN
Automation Chemist - Chemspeed
Bruker Nano Inc
Boston, MA
- $78,000 USD / year
Work closely with software developers and engineers to refine automation platforms and features
Added 11 mins ago
Sr Supplier Quality Engineer
Textron
Williamsport, PA
Collaborate with cross-functional teams, including engineering, production, and supply chain, to ensure quality standards are met throughout the product lifecycle.
Added 12 mins ago
Software Engineer
CoreLogic Solutions, LLC
Dallas, TX
Design, develop, test, deploy, and maintain scalable software applications following established engineering standards, coding best practices, and architectural guidelines under general…
Added 13 mins ago
G
Electrical Design Engineer
GPAC
Magnolia, AR
- $80,000 to $110,000 USD / year
Education: Bachelor’s degree in Electrical Engineering or a closely related discipline.
Added 15 mins ago
G
Steel Project Manager
GPAC
Birmingham, AL
- $75,000 to $115,000 USD / year
Proficient in project management and construction software, including Tekla, AutoCAD, Bluebeam, Fabtrol (or similar).
Added 16 mins ago
G
Steel Estimator
GPAC
Birmingham, AL
- $60,000 to $100,000 USD / year
Utilize industry-standard estimating software to generate proposals and bid packages.
Added 16 mins ago
G
Steel Detailer
GPAC
Birmingham, AL
- $60,000 to $95,000 USD / year
Create detailed fabrication and erection drawings for structural steel and miscellaneous metals (stairs, railings, catwalks, etc.) using industry-standard software.
Added 16 mins ago
G
Steel Project Manager
GPAC
Huntsville, AL
- $75,000 to $115,000 USD / year
Proficient in project management and construction software, including Tekla, AutoCAD, Bluebeam, Fabtrol (or similar).
Added 16 mins ago
G
Steel Estimator
GPAC
Huntsville, AL
- $60,000 to $100,000 USD / year
Utilize industry-standard estimating software to generate proposals and bid packages.
Added 16 mins ago
G
Steel Detailer
GPAC
Huntsville, AL
- $60,000 to $95,000 USD / year
Create detailed fabrication and erection drawings for structural steel and miscellaneous metals (stairs, railings, catwalks, etc.) using industry-standard software.
Added 16 mins ago
DevOps Engineer
Cascade Dafo Inc
Ferndale, WA
…infrastructure, automation, and deployment processes that enable reliable software delivery. This role partners closely with development and IT teams to improve system reliability, automate…
Added 16 mins ago
Toolmaker-CNC Program - Set Up Operator
Smith & Wesson
Springfield, MA
Working from engineering drawings and concepts to mark out design on raw materials; cutting into shape using manually controlled machine tools (such as lathes, milling machines, grinding…

CURIA

Principal Engineer

United States

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Job details

Experience: Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Posting language: English
Posted: Nov 4, 2026

Original job description

Principal Engineer – Filling & Lyophilization – United States Build your future at Curia, where our work has the power to save lives. The Principal Engineer will lead equipment engineering for large capital projects in sterile filling and lyophilization to support Curia’s strategic growth. This includes leading network-wide capital execution to expand, modernize, and standardize manufacturing infrastructure. The incumbent will direct the specification, procurement, installation, commissioning, and qualification of advanced aseptic technologies to increase capacity, efficiency, and compliance for drug product programs. This position interfaces with Curia’s network manufacturing sites, client technical teams, and global leadership. The role provides technical oversight, mentorship, and engineering guidance across site-based teams and major capital project teams. Curia is a global contract development and manufacturing organization (CDMO) with over 30 years of experience partnering with pharmaceutical and biotech companies to provide life-saving treatments to patients. At Curia, we are on a mission to advance our customers’ therapies from curiosity to cure and ultimately to improve patients’ lives. We proudly offer

Generous benefit options (eligible first day of employment)
Paid training, vacation and holidays (vacation accrual begins on first day of employment)
Career advancement opportunities
Education reimbursement
401K program with matching contributions
Learning platform
And more!

Responsibilities

Capital Project Execution: Lead filling and lyophilization equipment engineering for major capital projects ($10M–$50M+) from conceptual design through Commissioning, Qualification, and Validation (CQV)
Technical Transfer & Client Support: Drive robust, on-time technical transfers of API and Drug Product (DP) programs, partnering with the Global Program Management Office and site technical operation teams to satisfy client expectations
Equipment Specification & Procurement: Author User Requirement Specifications (URS), drive vendor selection, conduct capital cost estimation, and lead Factory/Site Acceptance Testing (FAT/SAT) for primary equipment (fill lines, isolators, lyos, VHP, capping)
Network Capability & Talent Development: Mentor site-based engineering teams across the Curia network, sharing best practices, upgrading skill sets, and driving technical standardization
Operational Excellence & Continuous Improvement: Partner with sites to troubleshoot complex equipment deviations, increase OEE, reduce cycle times, and execute cost-improvement programs
Vendor & Engineering Firm Management: Oversee external engineering design firms, equipment vendors, and field contractors for filling and lyophilization installations
Regulatory Compliance: Ensure all equipment and system designs comply with cGMP, EU Annex 1 (Contamination Control Strategy), FDA guidance, and global regulatory standards
This job has no direct supervisory responsibilities; serves as a technical lead and matrix manager for project teams and site engineering resources
Travel Requirement: Up to 40% travel, including international travel to plant sites and vendor facilities Education and Experience
Education: BS in Mechanical, Chemical, Electrical, or Biomedical Engineering (or related discipline)
Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Capital Projects: Proven track record leading major capital equipment execution projects exceeding $10M Technical Expertise: Advanced expertise in
Aseptic processing, high-speed sterile filling (vials, syringes, cartridges), and barrier technology (Isolators/RABS)
Lyophilization processes and automated loading/unloading systems (ALUS)
Decontamination systems (VHP / Hydrogen Peroxide Vapor)
Sterilization processes (SIP, Autoclaves, Depyrogenation Tunnels)
Critical Utilities (WFI, Clean Steam, Clean Compressed Air, Process Gases, Cleanrooms, and HVAC)
Commissioning, Qualification, and Validation (CQV / ISPE Baseline Guide approach)
Regulatory & Quality Knowledge: Deep understanding of global pharmaceutical regulations (FDA cGMP, EMA, EU Annex 1, PIC/S) Skills & Capabilities
Analytical & Problem Solving: Demonstrated root-cause analysis skills (e.g., FMEA, 6-Sigma) to address complex process and equipment deviations
Communication & Stakeholder Management: Excellent verbal and written communication skills with experience presenting technical concepts to executive leadership, site teams, and external clients
Computer & Software Skills: Proficient in project management software, CAD systems, CMMS, Trackwise/QMS systems, MS Office Suite (Word, Excel, PowerPoint), and process automation systems (PLC/SCADA/DCS) Other Qualifications & Requirements
Must pass a background check and drug screen
Ability to work in cleanroom environments (Gowning required) Physical Demands & Work Environment
Physical Demands: Regularly required to talk, hear, sit, stand, walk, reach, and lift up to 25–50 lbs
Work Environment: Mix of office environment, active construction sites, and cGMP cleanrooms. Moderate noise level with exposure to moving mechanical parts and industrial chemical/utility systems This job description in no way states or implies that these are the only duties to be performed by the employee(s) incumbent in this position. Employees will be required to follow any other job-related instructions and to perform any other job-related duties requested by any person authorized to give instructions or assignments. All duties and responsibilities are essential functions and requirements and are subject to possible modification to reasonably accommodate individuals with disabilities. To perform this job successfully, the incumbents will possess the skills, aptitudes, and abilities to perform each duty proficiently. Some requirements may exclude individuals who pose a direct threat or significant risk to the health or safety of themselves or others. The requirements listed in this document are the minimum levels of knowledge, skills, or abilities. This document does not create an employment contract, implied or otherwise, other than an “at will” relationship.

Salary range:$120,200-$144,100/year Education, experience, location and tenure may be considered along with internal equity when job offers are extended. We do not accept unsolicited assistance from any headhunters or recruitment firms for any of our job openings. All resumes or profiles submitted by search firms to any employee at Curia, in any form without a valid, signed search agreement by an authorized signatory in place for the specific position, approved by Talent Acquisition, will be deemed the sole property of Curia. No fee will be paid in the event the candidate is hired by Curia because of the unsolicited referral.

All interested applicants must apply online. Please be aware of scammers. Curia will only send offer letters and requests for sensitive personal information from a curiaglobal.com email address. Curia is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Curia is an E-Verify employer.

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More about this job

Skills

Procurement
Regulatory compliance
Program management
Microsoft Office
Estimating
Process improvement
Troubleshoot
Biomedical engineering
Pharmaceutical technology
SIP
HVAC
Pharmaceutical legislation
Problem solving
Root cause analysis
Communication skills
Stakeholder management
Project management
CMMS
Microsoft Word
Microsoft Excel
Microsoft PowerPoint
PLC
SCADA
DCS
Heavy lifting

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