Jobs in the United States

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Added 1 min ago
Mechanical Engineer
Actalent
Hauppauge, NY
An award-winning engineering services company in Hauppauge, NY is seeking an experienced Senior Mechanical Design Engineer to join its growing engineering team.This is an excellent…
Added 1 min ago
A
Electrical Design Engineer
Actalent
Clearwater, FL
- $140,000 to $150,000 USD / year
Experience with Altium or similar electronic design automation tools for schematic capture and PCB layout.
Added 1 min ago
A
Firmware Test Engineer
Actalent
Solon, OH
- $35 to $40 USD / hour
…embedded firmware across a range of products. The Firmware Test Engineer designs, implements, and maintains firmware tests, analyzes test results and failures, and collaborates closely with…
Added 1 min ago
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Senior Site Reliability Engineer
Xplor
Remote, United States
- $150,000 to $200,000 USD / year
Xplor Technologies powers the experiences at the heart of everyday life. Through modern vertical software, embedded payments, and AI-powered capabilities, we help businesses in fitness,…
Added 1 min ago
A
Mechanical Application Engineer
Actalent
Dallas, TX
- $70,000 to $95,000 USD / year
Job Title: Mechanical Application EngineerJob DescriptionThe Mechanical Application Engineer plays a key role in the engineering, design, and support of packaged equipment solutions across…
Added 1 min ago
CR
Head of AI Transformation, Engineering & SaaS Operations, MD
Charles River Systems Inc MA
United States
- $170,000 to $282,500 USD / year
Deploy and scale coding copilots, engineering agents, and software delivery automation capabilities.
Added 2 mins ago
IG
Platform Security Engineer (AWS)
Insight Global
McLean, VA
- From $88 USD / hour
We need a hands-on DevSecOps/Cybersecurity Engineer who understands AWS, software engineering and automation, but has deeper expertise implementing security and compliance requirements like…
Added 2 mins ago
IG
Full Stack Development Engineer
Insight Global
McLean, VA
- From $88 USD / hour
- 7+ years Full Stack Software Engineering Experience (Preferred Stack is Golang and React, however the team is flexible)
Added 2 mins ago
IG
Senior Controls Software Engineer
Insight Global
Dunwoody, GA
- From $80 USD / hour
10+ years of controls, automation, or software integration experience
Added 3 mins ago
Senior Automation Engineer, RME
Amazon.com Services LLC
Pooler, GA
As a Senior Automation Engineer, you will play a crucial role in maximizing equipment reliability and operational performance in our fulfillment centers by providing proactive controls…
Added 5 mins ago
Undergraduate Rotational Electrical Engineer
Worley
Baton Rouge, LA
Developing skills in electrical, Instrumentation, and automation engineering-specific software.
Added 5 mins ago
Manufacturing Engineer
Socomec
Suwanee, GA
We are seeking a Manufacturing Engineer to join our team and support the assembly and production of Static Transfer Switches (STS) and Datacenter Uninterruptible Power Supply (UPS) systems.…
Added 5 mins ago
Senior Vice President, Infrastructure Engineering (Mainframe Communications Systems Software Engineer
ewminds consulting Services
Jersey City, NJ
(SVP) Senior Vice President, Infrastructure Engineering (Mainframe Communications Systems Software Engineer)
Added 8 mins ago
Senior AI Engineer, Release Engineering
Intercontinental Exchange Holdings, Inc.
Atlanta, GA
The Senior Engineer is a full-stack engineer with strong AI and large language model (LLM) expertise, embedded within the Release Engineering Development team. This team designs and…
Added 9 mins ago
Primary Job Template
Quince
Carneys Point, NJ
We’re looking for an IT Engineer II to join our growing North America IT team. In this role, you will help ensure reliable IT operations, secure device and access management, and a seamless…
Added 13 mins ago
Controls Engineer- ON SITE
Ebara Mixers Inc.
Adelanto, CA
…machine leaving the shop floor? We’re looking for a Controls Engineer who wants true end-to-end ownership of control systems: scoping and estimating the job, designing the system, building…
Added 16 mins ago
SS
Head of AI Transformation, Engineering & SaaS Operations, MD
State Street
Burlington, MA
- $170,000 to $282,500 USD / year
Deploy and scale coding copilots, engineering agents, and software delivery automation capabilities.
Added 19 mins ago
Senior Python Software Engineer III
JPMC page
Houston, TX
Applies knowledge of tools within the Software Development Life Cycle toolchain, including enterprise-authorized AI-assisted development and automation capabilities, to improve the value…
Added 20 mins ago
A
Senior Software Engineer, Fullstack
Assured
New York City, NY
- $180,000 to $200,000 USD / year
We’re looking for a Software Engineer to help architect, build, and productize our AI/ML infrastructure. You'll be the bridge between research, product, customers, and engineering, driving…
Added 21 mins ago
BA
Systems Engineer, Mid
Booz Allen Hamilton
Colorado Springs, CO
- $61,900 to $141,000 USD / year
Join a mission-focused team supporting the modernization, automation, and secure delivery of enterprise IT capabilities. As a Systems Administrator, you will help maintain and evolve our…
Added 22 mins ago
Senior Software Development Engineer in Test (SDET) - Remote
Scalepex
Remote, United States
Scalepex is actively seeking an experienced Senior Software Development Engineer in Test (SDET) for an exciting remote opportunity in the digital healthcare technology space.
Added 22 mins ago
Manufacturing Engineer II
Aerospace
Lansdale, PA
Honeywell helps organizations solve the world's most complex challenges in automation, the future of aviation and energy transition. As a trusted partner, we provide actionable solutions…
Added 23 mins ago
M
Systems Engineer Level 3
Markon
Fort Meade, MD
- $200,000 to $220,000 USD / year
Markon is seeking a Systems Engineer Level 3 to support the Fort Meade Customer. This role focuses on designing, integrating, and maintaining mission-critical RF and FORNSAT systems, GOTS…
Added 24 mins ago
Software Test Engineer
GIGATEC Engineering
Annapolis Junction, MD
We are seeking a skilled Software Test Engineer who thrives on solving complex technical challenges including planning, developing, executing, and automating testing activities for software…
Added 24 mins ago
Software Engineer
DCS Corporation
Sterling Heights, MI, MI
DCS is looking for a Senior Software Engineer to support the Bradley combat vehicles, A3 and A4, Post Production Support Software effort, by resolving know issues and incorporating new…

CURIA

Principal Engineer

United States

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Job details

Experience: Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Posting language: English
Posted: Nov 4, 2026

Original job description

Principal Engineer – Filling & Lyophilization – United States Build your future at Curia, where our work has the power to save lives. The Principal Engineer will lead equipment engineering for large capital projects in sterile filling and lyophilization to support Curia’s strategic growth. This includes leading network-wide capital execution to expand, modernize, and standardize manufacturing infrastructure. The incumbent will direct the specification, procurement, installation, commissioning, and qualification of advanced aseptic technologies to increase capacity, efficiency, and compliance for drug product programs. This position interfaces with Curia’s network manufacturing sites, client technical teams, and global leadership. The role provides technical oversight, mentorship, and engineering guidance across site-based teams and major capital project teams. Curia is a global contract development and manufacturing organization (CDMO) with over 30 years of experience partnering with pharmaceutical and biotech companies to provide life-saving treatments to patients. At Curia, we are on a mission to advance our customers’ therapies from curiosity to cure and ultimately to improve patients’ lives. We proudly offer

Generous benefit options (eligible first day of employment)
Paid training, vacation and holidays (vacation accrual begins on first day of employment)
Career advancement opportunities
Education reimbursement
401K program with matching contributions
Learning platform
And more!

Responsibilities

Capital Project Execution: Lead filling and lyophilization equipment engineering for major capital projects ($10M–$50M+) from conceptual design through Commissioning, Qualification, and Validation (CQV)
Technical Transfer & Client Support: Drive robust, on-time technical transfers of API and Drug Product (DP) programs, partnering with the Global Program Management Office and site technical operation teams to satisfy client expectations
Equipment Specification & Procurement: Author User Requirement Specifications (URS), drive vendor selection, conduct capital cost estimation, and lead Factory/Site Acceptance Testing (FAT/SAT) for primary equipment (fill lines, isolators, lyos, VHP, capping)
Network Capability & Talent Development: Mentor site-based engineering teams across the Curia network, sharing best practices, upgrading skill sets, and driving technical standardization
Operational Excellence & Continuous Improvement: Partner with sites to troubleshoot complex equipment deviations, increase OEE, reduce cycle times, and execute cost-improvement programs
Vendor & Engineering Firm Management: Oversee external engineering design firms, equipment vendors, and field contractors for filling and lyophilization installations
Regulatory Compliance: Ensure all equipment and system designs comply with cGMP, EU Annex 1 (Contamination Control Strategy), FDA guidance, and global regulatory standards
This job has no direct supervisory responsibilities; serves as a technical lead and matrix manager for project teams and site engineering resources
Travel Requirement: Up to 40% travel, including international travel to plant sites and vendor facilities Education and Experience
Education: BS in Mechanical, Chemical, Electrical, or Biomedical Engineering (or related discipline)
Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Capital Projects: Proven track record leading major capital equipment execution projects exceeding $10M Technical Expertise: Advanced expertise in
Aseptic processing, high-speed sterile filling (vials, syringes, cartridges), and barrier technology (Isolators/RABS)
Lyophilization processes and automated loading/unloading systems (ALUS)
Decontamination systems (VHP / Hydrogen Peroxide Vapor)
Sterilization processes (SIP, Autoclaves, Depyrogenation Tunnels)
Critical Utilities (WFI, Clean Steam, Clean Compressed Air, Process Gases, Cleanrooms, and HVAC)
Commissioning, Qualification, and Validation (CQV / ISPE Baseline Guide approach)
Regulatory & Quality Knowledge: Deep understanding of global pharmaceutical regulations (FDA cGMP, EMA, EU Annex 1, PIC/S) Skills & Capabilities
Analytical & Problem Solving: Demonstrated root-cause analysis skills (e.g., FMEA, 6-Sigma) to address complex process and equipment deviations
Communication & Stakeholder Management: Excellent verbal and written communication skills with experience presenting technical concepts to executive leadership, site teams, and external clients
Computer & Software Skills: Proficient in project management software, CAD systems, CMMS, Trackwise/QMS systems, MS Office Suite (Word, Excel, PowerPoint), and process automation systems (PLC/SCADA/DCS) Other Qualifications & Requirements
Must pass a background check and drug screen
Ability to work in cleanroom environments (Gowning required) Physical Demands & Work Environment
Physical Demands: Regularly required to talk, hear, sit, stand, walk, reach, and lift up to 25–50 lbs
Work Environment: Mix of office environment, active construction sites, and cGMP cleanrooms. Moderate noise level with exposure to moving mechanical parts and industrial chemical/utility systems This job description in no way states or implies that these are the only duties to be performed by the employee(s) incumbent in this position. Employees will be required to follow any other job-related instructions and to perform any other job-related duties requested by any person authorized to give instructions or assignments. All duties and responsibilities are essential functions and requirements and are subject to possible modification to reasonably accommodate individuals with disabilities. To perform this job successfully, the incumbents will possess the skills, aptitudes, and abilities to perform each duty proficiently. Some requirements may exclude individuals who pose a direct threat or significant risk to the health or safety of themselves or others. The requirements listed in this document are the minimum levels of knowledge, skills, or abilities. This document does not create an employment contract, implied or otherwise, other than an “at will” relationship.

Salary range:$120,200-$144,100/year Education, experience, location and tenure may be considered along with internal equity when job offers are extended. We do not accept unsolicited assistance from any headhunters or recruitment firms for any of our job openings. All resumes or profiles submitted by search firms to any employee at Curia, in any form without a valid, signed search agreement by an authorized signatory in place for the specific position, approved by Talent Acquisition, will be deemed the sole property of Curia. No fee will be paid in the event the candidate is hired by Curia because of the unsolicited referral.

All interested applicants must apply online. Please be aware of scammers. Curia will only send offer letters and requests for sensitive personal information from a curiaglobal.com email address. Curia is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Curia is an E-Verify employer.

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More about this job

Skills

Procurement
Regulatory compliance
Program management
Microsoft Office
Estimating
Process improvement
Troubleshoot
Biomedical engineering
Pharmaceutical technology
SIP
HVAC
Pharmaceutical legislation
Problem solving
Root cause analysis
Communication skills
Stakeholder management
Project management
CMMS
Microsoft Word
Microsoft Excel
Microsoft PowerPoint
PLC
SCADA
DCS
Heavy lifting

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