Jobs in the United States

25+ jobs

Save this search

Added just now
Product Development Engineer II
PMT Corporation
Chanhassen, MN
…plastic / reconstruction surgery areas. The Product Development Engineer II takes ownership of medium- to large-scale projects from concept through commercialization, ensuring products are…
Added 1 min ago
Senior Systems Integration Engineer
DISHER
Southern Pines, NC
DISHER is partnering with a military consulting company to add an experienced Senior Systems Integration Engineer. You will be supporting the implementation and technical execution of…
Added 3 mins ago
Senior Product Engineer
Henry Pratt Company, LLC
Kimball, TN
Senior Product EngineerMueller Water Products is the nation's leading manufacturer of flow control devices for the water and gas distribution industries and has an immediate opening for a…
Added 3 mins ago
Sr. Systems Engineer II
Proconex
Royersford, PA
The Senior Systems Engineer II applies expert-level process control and automation knowledge to architect solutions, optimize manufacturing operations, mentor engineers, improve engineering…
Added 4 mins ago
Construction Quality Engineer - Electrical, Instrumentation & Controls (ICE)
Bureau Veritas
Chicago
Construction Quality Engineer – Electrical, Instrumentation & Controls (ICE)
Added 7 mins ago
UI
Quality Engineer
Uniloy INC
Tecumseh, MI
- $73,000 to $83,000 USD / year
Apply quality, operations, analytical, project management, and continuous improvement principles to support business objectives, improve operational performance, and facilitate data-driven…
Added 7 mins ago
UI
Controls Engineer Working Lead
Uniloy INC
Tecumseh, MI
- $130,000 to $150,000 USD / year
Design, develop, and document control and HMI software for blow molding equipment, using advanced concepts and design practices.
Added 8 mins ago
Senior Cybersecurity IAM Engineer
Louisiana Health Service & Indemnity Company
Remote, United States
…maintenance of IAM security processes and procedures. Supports project and operational teams in enrolling and integrating their solutions with the IAM service. Accountable for complying…
Added 8 mins ago
Lead Engineering Associate II
Aerospace
Minneapolis, MN
As a Lead Engineer Associate II here at Honeywell Aerospace, you will take a lead role in engineering projects, providing technical expertise and guidance to ensure successful project…
Added 9 mins ago
Project Manager - Civil Engineer
Dynamic Engineering Consultants, PC
Philadelphia, PA
Project Management in the areas of Land Development Plan Design, Stormwater Management Design, Water and Sanitary Sewer Design and Erosion and Sedimentation Control Design
Added 12 mins ago
TE
Project Controls Engineer, OT SCADA Projects (TEMP)
Terabase Energy
Remote, United States
- $120,000 to $130,000 USD / year
The Project Controls Engineer supports the design, configuration, commissioning, and documentation of plant control systems for utility-scale solar, storage, and hybrid renewable energy…
Added 13 mins ago
Preconstruction Project Engineer
RNGD
Metairie, LA
We’re looking for a Preconstruction Project Engineer that will support the development of accurate, competitive, and well-coordinated preconstruction deliverables while building practical…
Added 13 mins ago
Project Engineer
About Us
Goodyear, AZ
Our Project Engineer assists their Project Manager on projects and is the liaison between the field and the office. In this role, the PE is responsible for defining the project’s objectives…
Added 15 mins ago
Subject Matter Expert (Manufacturing Engineer) - Optics Polishing
Coherent Corp. US
Budd Lake, NJ
Establish and optimize process parameters for dimensional, surface, and optical quality requirements.
Added 16 mins ago
Firmware Engineer
Mirion
Melbourne, FL
The Embedded Firmware Engineer I will support the development and sustaining engineering of embedded systems used in radiation measurement and medical-device instrumentation. This…
Added 17 mins ago
Azure Data Engineer- Lead
Spyglass
Remote, United States
As a Lead Azure Data Engineer, you will work as part of our Azure Data and Analytics practice by leading the design, development, and delivery of modern cloud data solutions for our…
Added 18 mins ago
Subject Matter Expert (Manufacturing Engineer) - Optics Polishing
Coherent Corp. US
Budd Lake, NJ
Establish and optimize process parameters for dimensional, surface, and optical quality requirements.
Added 19 mins ago
BIM Coordinator
Tetra Tech, Inc
Portland, OR
…projects through effective BIM coordination, model management, quality control, and collaboration with multidisciplinary project teams. This position follows a hybrid work arrangement…
Added 19 mins ago
Senior SailPoint Administrator
BCBSM, Inc.
Eagan, MN
Maintain identity attribute mappings, correlation logic, and authoritative source data quality.
Added 20 mins ago
CA Building Group Field Engineer I
Sundt
Sacramento, CA
Assists the Project Engineer with being the technical source of information for the project. Responds to questions about drawings, specifications, shop drawings, and change orders and have…
Added 20 mins ago
Project Engineer (GPC)
Great Place Construction Company
sioux falls, SD
Great Place Construction is a private construction firm that specializes in commercial construction. We are seeking a Project Engineer to join our team to facilitate, analyze and manage…
Added 21 mins ago
Associate Mechanical Engineer
United Integrated Services (USA) Corp.
Phoenix, AZ
Summary: The Associate Mechanical Engineer will work closely with design, construction, and commissioning teams to ensure the successful delivery of cleanroom projects that meet stringent…
Added 21 mins ago
Project Engineer
Honeybee Robotics, LLC
Longmont, CO
…manage and coordinate engineering and technical aspects of a project, ensuring it meets deadlines, budgets, and quality standards. You will be the primary point-of-contact to our customers…
Added 21 mins ago
Tooling Design Engineer II
Blue Origin Personnel, LLC
United States
This role is part of Blue Origin Operations, which is comprised of Integrated Supply Chain, Test Operations, Safety, Quality, and Mission Assurance. This includes Manufacturing and Supply…
Added 23 mins ago
Mechanical Designer/Engineer
Mazzetti, INC.
United States
Mazzetti is seeking a Mechanical Designer/Engineer based in the greater St. Louis area to join our engineering practice and contribute fully to the analysis, design, and documentation of…

CURIA

Principal Engineer

United States

Apply About employer

Applications open in a new tab.

Job details

Experience: Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Posting language: English
Posted: Nov 4, 2026

Original job description

Principal Engineer – Filling & Lyophilization – United States Build your future at Curia, where our work has the power to save lives. The Principal Engineer will lead equipment engineering for large capital projects in sterile filling and lyophilization to support Curia’s strategic growth. This includes leading network-wide capital execution to expand, modernize, and standardize manufacturing infrastructure. The incumbent will direct the specification, procurement, installation, commissioning, and qualification of advanced aseptic technologies to increase capacity, efficiency, and compliance for drug product programs. This position interfaces with Curia’s network manufacturing sites, client technical teams, and global leadership. The role provides technical oversight, mentorship, and engineering guidance across site-based teams and major capital project teams. Curia is a global contract development and manufacturing organization (CDMO) with over 30 years of experience partnering with pharmaceutical and biotech companies to provide life-saving treatments to patients. At Curia, we are on a mission to advance our customers’ therapies from curiosity to cure and ultimately to improve patients’ lives. We proudly offer

Generous benefit options (eligible first day of employment)
Paid training, vacation and holidays (vacation accrual begins on first day of employment)
Career advancement opportunities
Education reimbursement
401K program with matching contributions
Learning platform
And more!

Responsibilities

Capital Project Execution: Lead filling and lyophilization equipment engineering for major capital projects ($10M–$50M+) from conceptual design through Commissioning, Qualification, and Validation (CQV)
Technical Transfer & Client Support: Drive robust, on-time technical transfers of API and Drug Product (DP) programs, partnering with the Global Program Management Office and site technical operation teams to satisfy client expectations
Equipment Specification & Procurement: Author User Requirement Specifications (URS), drive vendor selection, conduct capital cost estimation, and lead Factory/Site Acceptance Testing (FAT/SAT) for primary equipment (fill lines, isolators, lyos, VHP, capping)
Network Capability & Talent Development: Mentor site-based engineering teams across the Curia network, sharing best practices, upgrading skill sets, and driving technical standardization
Operational Excellence & Continuous Improvement: Partner with sites to troubleshoot complex equipment deviations, increase OEE, reduce cycle times, and execute cost-improvement programs
Vendor & Engineering Firm Management: Oversee external engineering design firms, equipment vendors, and field contractors for filling and lyophilization installations
Regulatory Compliance: Ensure all equipment and system designs comply with cGMP, EU Annex 1 (Contamination Control Strategy), FDA guidance, and global regulatory standards
This job has no direct supervisory responsibilities; serves as a technical lead and matrix manager for project teams and site engineering resources
Travel Requirement: Up to 40% travel, including international travel to plant sites and vendor facilities Education and Experience
Education: BS in Mechanical, Chemical, Electrical, or Biomedical Engineering (or related discipline)
Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Capital Projects: Proven track record leading major capital equipment execution projects exceeding $10M Technical Expertise: Advanced expertise in
Aseptic processing, high-speed sterile filling (vials, syringes, cartridges), and barrier technology (Isolators/RABS)
Lyophilization processes and automated loading/unloading systems (ALUS)
Decontamination systems (VHP / Hydrogen Peroxide Vapor)
Sterilization processes (SIP, Autoclaves, Depyrogenation Tunnels)
Critical Utilities (WFI, Clean Steam, Clean Compressed Air, Process Gases, Cleanrooms, and HVAC)
Commissioning, Qualification, and Validation (CQV / ISPE Baseline Guide approach)
Regulatory & Quality Knowledge: Deep understanding of global pharmaceutical regulations (FDA cGMP, EMA, EU Annex 1, PIC/S) Skills & Capabilities
Analytical & Problem Solving: Demonstrated root-cause analysis skills (e.g., FMEA, 6-Sigma) to address complex process and equipment deviations
Communication & Stakeholder Management: Excellent verbal and written communication skills with experience presenting technical concepts to executive leadership, site teams, and external clients
Computer & Software Skills: Proficient in project management software, CAD systems, CMMS, Trackwise/QMS systems, MS Office Suite (Word, Excel, PowerPoint), and process automation systems (PLC/SCADA/DCS) Other Qualifications & Requirements
Must pass a background check and drug screen
Ability to work in cleanroom environments (Gowning required) Physical Demands & Work Environment
Physical Demands: Regularly required to talk, hear, sit, stand, walk, reach, and lift up to 25–50 lbs
Work Environment: Mix of office environment, active construction sites, and cGMP cleanrooms. Moderate noise level with exposure to moving mechanical parts and industrial chemical/utility systems This job description in no way states or implies that these are the only duties to be performed by the employee(s) incumbent in this position. Employees will be required to follow any other job-related instructions and to perform any other job-related duties requested by any person authorized to give instructions or assignments. All duties and responsibilities are essential functions and requirements and are subject to possible modification to reasonably accommodate individuals with disabilities. To perform this job successfully, the incumbents will possess the skills, aptitudes, and abilities to perform each duty proficiently. Some requirements may exclude individuals who pose a direct threat or significant risk to the health or safety of themselves or others. The requirements listed in this document are the minimum levels of knowledge, skills, or abilities. This document does not create an employment contract, implied or otherwise, other than an “at will” relationship.

Salary range:$120,200-$144,100/year Education, experience, location and tenure may be considered along with internal equity when job offers are extended. We do not accept unsolicited assistance from any headhunters or recruitment firms for any of our job openings. All resumes or profiles submitted by search firms to any employee at Curia, in any form without a valid, signed search agreement by an authorized signatory in place for the specific position, approved by Talent Acquisition, will be deemed the sole property of Curia. No fee will be paid in the event the candidate is hired by Curia because of the unsolicited referral.

All interested applicants must apply online. Please be aware of scammers. Curia will only send offer letters and requests for sensitive personal information from a curiaglobal.com email address. Curia is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Curia is an E-Verify employer.

Apply About employer

More about this job

Skills

Procurement
Regulatory compliance
Program management
Microsoft Office
Estimating
Process improvement
Troubleshoot
Biomedical engineering
Pharmaceutical technology
SIP
HVAC
Pharmaceutical legislation
Problem solving
Root cause analysis
Communication skills
Stakeholder management
Project management
CMMS
Microsoft Word
Microsoft Excel
Microsoft PowerPoint
PLC
SCADA
DCS
Heavy lifting

Report this job