Jobs in the United States

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Added 1 min ago
SR
Project Manager
ServiceMaster Restoration by Spotless
Oceanside, CA
- $70,000 to $90,000 USD / year
ServiceMaster by Spotless is seeking an organized, customer-focused Restoration Project Manager to oversee residential and commercial property restoration projects throughout San Diego…
Added 13 mins ago
MM
Asphalt Plant Manager
Martin Marietta Materials, Inc
Lakewood, CO
- $110,000 to $153,000 USD / year
Career Development Framework ("CDF") Information:
Added 13 mins ago
UT
Klamath Project Manager
USA The Nature Conservancy
Etna, CA
- $82,700 to $97,275 USD / year
The Klamath Project Manager develops, manages, and advances innovative streamflow, agricultural water management, and riparian restoration projects that improve river flows and restore…
Added 14 mins ago
Senior Capital Projects Manager
Calumet Specialty Products Partners L.P.
Great Falls, MT
The Sr. Capital Projects Manager plays a pivotal role in leading large-scale investment and infrastructure projects from concept through completion at the facility. This position blends…
Added 14 mins ago
Transmission Line Project Engineer (Rocky Mountain)- Remote
WSP USA
Bozeman, MT · Billings, MT
…line projects. Tasks may include research, design, concept development, planning, client interactions, business and proposal development, construction support, and staff mentorship.…
Added 14 mins ago
Wildland Firefighter - Helicopter Manager
State of Montana
Billings, MT
Added 14 mins ago
O
Software Development Manager
Oracle
Helena, MT
- $112,800 to $264,100 USD / year
We are looking for a hands-on engineering manager to lead the Authorization team within IAM. This team is responsible for designing, building, and operating critical authorization services…
Added 14 mins ago
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Director of Public School Strategy – Scholarship Services
Nelnet
Helena, MT
- $160,000 to $175,000 USD / year
This position sits within FACTS' scholarship services business development team, though business development is a secondary, downstream function of this role rather than its purpose. As…
Added 14 mins ago
Healthcare .NET Senior Application Developer - HNAS
Highmark Health
Helena, MT
This job takes the lead in providing more complex application development services typically as part of a project team or in an application support role. Developers analyze, design, code,…
Added 14 mins ago
Analyst, Product Support
SitusAMC
Helena, MT
Performs Testing of Inhouse Applications for Project and Support-related activities
Added 14 mins ago
Manager Database Administrator - Remote US
SitusAMC
Helena, MT
Work with the project team and business teams to ensure database designs meet project and business requirements
Added 14 mins ago
GA
Sr Technical Program Manager
GE Aerospace
Helena, MT
- $95,000 to $150,000 USD / year
Working as the Program Manager – Global Mobility & Talent Management Technology, you will be responsible for working in lock-step with application or domain leaders acting as a senior…
Added 14 mins ago
Platform Engineer - Remote
SitusAMC
Helena, MT
Develop and maintain the in-house CI/CD automation pipeline as an individual contributor on the Cloud development platform team.
Added 14 mins ago
Sr Payment Integrity Consultant - Payment Integrity
HCSC
Helena, MT
…reporting KPIs and impact metrics, working with the PI Program Manager to draft communications on PI project progress, impact, value, and…
Added 14 mins ago
UI Software Developer - .Net - Remote
SitusAMC
Helena, MT
…user needs. This role requires a strong background in software development, problem-solving skills, and a passion for…
Added 14 mins ago
Laboratory Manager
Unified Women's Healthcare
Houston, TX
The Laboratory Manager plays a vital role in the overall safety of the laboratory and is responsible for managing daily operations of the lab. The laboratory manager takes responsibilities…
Added 15 mins ago
Technical Manager, Information Security
Atomic Machines
Emeryville or Santa Clara, CA
This is a broad-responsibility, high-judgment individual contributor role within the IT team. The Technical Manager, Cybersecurity Engineering is a hands-on leadership role responsible for…
Added 17 mins ago
GE
Sr Technical Program Manager
General Electric Company
NY
- $95,000 to $150,000 USD / year
Working as the Program Manager – Global Mobility & Talent Management Technology, you will be responsible for working in lock-step with application or domain leaders acting as a senior…
Added 17 mins ago
Lead Supplier Development, Industrialization & Quality Engineer - Battery Cell
Rivian
Irvine, CA
…and reliability of our vehicle programs. As a Lead Supplier Development, Industrialization & Quality Engineer, you are an advanced individual contributor and subject matter expert…
Added 17 mins ago
Staff Technical Program Manager, Diagnostic Engineering
Rivian
Hayward, CA · Irvine, CA
Collaborate with related stakeholders across Rivian Service to align on project(s) goals, prioritization, roadmaps, and track progress from concept to launch/grow/optimize each project.
Added 18 mins ago
Sr. Director, Subscription Services
Planview Incorporated
UNAVAILABLE
Help customers define practical AI strategies for portfolio, project, and work management use cases.
Added 19 mins ago
Product Marketing Manager - Trading
moomoo
Jersey City, NJ
We are seeking a motivated and data-driven Integrated Marketing Manager with strong product marketing capabilities to drive marketing efforts targeting stock, options, crypto, and…
Added 26 mins ago
Scientific Director
Signal Pharmaceuticals, L
San Diego, CA
…relevant to the Protein Homeostasis Thematic Research Center project portfolio in collaboration with a broad group of…
Added 31 mins ago
Engineering Manager- Data Collection & Scanning
Jobgether
Remote, United States
…applications and next steps. Our partner is looking for an Engineering Manager – Data Collection & Scanning based in the United…
Added 31 mins ago
Quality Assurance Manager - Government Operations
Emmes Group
Rockville
The Manager Quality Assurance (QA) oversees aspects of the quality program at Emmes and manages staff within the QA Department. The Manager works with QA, company, and project leadership to…

CURIA

Principal Engineer

United States

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Job details

Experience: Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Posting language: English
Posted: Nov 4, 2026

Original job description

Principal Engineer – Filling & Lyophilization – United States Build your future at Curia, where our work has the power to save lives. The Principal Engineer will lead equipment engineering for large capital projects in sterile filling and lyophilization to support Curia’s strategic growth. This includes leading network-wide capital execution to expand, modernize, and standardize manufacturing infrastructure. The incumbent will direct the specification, procurement, installation, commissioning, and qualification of advanced aseptic technologies to increase capacity, efficiency, and compliance for drug product programs. This position interfaces with Curia’s network manufacturing sites, client technical teams, and global leadership. The role provides technical oversight, mentorship, and engineering guidance across site-based teams and major capital project teams. Curia is a global contract development and manufacturing organization (CDMO) with over 30 years of experience partnering with pharmaceutical and biotech companies to provide life-saving treatments to patients. At Curia, we are on a mission to advance our customers’ therapies from curiosity to cure and ultimately to improve patients’ lives. We proudly offer

Generous benefit options (eligible first day of employment)
Paid training, vacation and holidays (vacation accrual begins on first day of employment)
Career advancement opportunities
Education reimbursement
401K program with matching contributions
Learning platform
And more!

Responsibilities

Capital Project Execution: Lead filling and lyophilization equipment engineering for major capital projects ($10M–$50M+) from conceptual design through Commissioning, Qualification, and Validation (CQV)
Technical Transfer & Client Support: Drive robust, on-time technical transfers of API and Drug Product (DP) programs, partnering with the Global Program Management Office and site technical operation teams to satisfy client expectations
Equipment Specification & Procurement: Author User Requirement Specifications (URS), drive vendor selection, conduct capital cost estimation, and lead Factory/Site Acceptance Testing (FAT/SAT) for primary equipment (fill lines, isolators, lyos, VHP, capping)
Network Capability & Talent Development: Mentor site-based engineering teams across the Curia network, sharing best practices, upgrading skill sets, and driving technical standardization
Operational Excellence & Continuous Improvement: Partner with sites to troubleshoot complex equipment deviations, increase OEE, reduce cycle times, and execute cost-improvement programs
Vendor & Engineering Firm Management: Oversee external engineering design firms, equipment vendors, and field contractors for filling and lyophilization installations
Regulatory Compliance: Ensure all equipment and system designs comply with cGMP, EU Annex 1 (Contamination Control Strategy), FDA guidance, and global regulatory standards
This job has no direct supervisory responsibilities; serves as a technical lead and matrix manager for project teams and site engineering resources
Travel Requirement: Up to 40% travel, including international travel to plant sites and vendor facilities Education and Experience
Education: BS in Mechanical, Chemical, Electrical, or Biomedical Engineering (or related discipline)
Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Capital Projects: Proven track record leading major capital equipment execution projects exceeding $10M Technical Expertise: Advanced expertise in
Aseptic processing, high-speed sterile filling (vials, syringes, cartridges), and barrier technology (Isolators/RABS)
Lyophilization processes and automated loading/unloading systems (ALUS)
Decontamination systems (VHP / Hydrogen Peroxide Vapor)
Sterilization processes (SIP, Autoclaves, Depyrogenation Tunnels)
Critical Utilities (WFI, Clean Steam, Clean Compressed Air, Process Gases, Cleanrooms, and HVAC)
Commissioning, Qualification, and Validation (CQV / ISPE Baseline Guide approach)
Regulatory & Quality Knowledge: Deep understanding of global pharmaceutical regulations (FDA cGMP, EMA, EU Annex 1, PIC/S) Skills & Capabilities
Analytical & Problem Solving: Demonstrated root-cause analysis skills (e.g., FMEA, 6-Sigma) to address complex process and equipment deviations
Communication & Stakeholder Management: Excellent verbal and written communication skills with experience presenting technical concepts to executive leadership, site teams, and external clients
Computer & Software Skills: Proficient in project management software, CAD systems, CMMS, Trackwise/QMS systems, MS Office Suite (Word, Excel, PowerPoint), and process automation systems (PLC/SCADA/DCS) Other Qualifications & Requirements
Must pass a background check and drug screen
Ability to work in cleanroom environments (Gowning required) Physical Demands & Work Environment
Physical Demands: Regularly required to talk, hear, sit, stand, walk, reach, and lift up to 25–50 lbs
Work Environment: Mix of office environment, active construction sites, and cGMP cleanrooms. Moderate noise level with exposure to moving mechanical parts and industrial chemical/utility systems This job description in no way states or implies that these are the only duties to be performed by the employee(s) incumbent in this position. Employees will be required to follow any other job-related instructions and to perform any other job-related duties requested by any person authorized to give instructions or assignments. All duties and responsibilities are essential functions and requirements and are subject to possible modification to reasonably accommodate individuals with disabilities. To perform this job successfully, the incumbents will possess the skills, aptitudes, and abilities to perform each duty proficiently. Some requirements may exclude individuals who pose a direct threat or significant risk to the health or safety of themselves or others. The requirements listed in this document are the minimum levels of knowledge, skills, or abilities. This document does not create an employment contract, implied or otherwise, other than an “at will” relationship.

Salary range:$120,200-$144,100/year Education, experience, location and tenure may be considered along with internal equity when job offers are extended. We do not accept unsolicited assistance from any headhunters or recruitment firms for any of our job openings. All resumes or profiles submitted by search firms to any employee at Curia, in any form without a valid, signed search agreement by an authorized signatory in place for the specific position, approved by Talent Acquisition, will be deemed the sole property of Curia. No fee will be paid in the event the candidate is hired by Curia because of the unsolicited referral.

All interested applicants must apply online. Please be aware of scammers. Curia will only send offer letters and requests for sensitive personal information from a curiaglobal.com email address. Curia is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Curia is an E-Verify employer.

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More about this job

Skills

Procurement
Regulatory compliance
Program management
Microsoft Office
Estimating
Process improvement
Troubleshoot
Biomedical engineering
Pharmaceutical technology
SIP
HVAC
Pharmaceutical legislation
Problem solving
Root cause analysis
Communication skills
Stakeholder management
Project management
CMMS
Microsoft Word
Microsoft Excel
Microsoft PowerPoint
PLC
SCADA
DCS
Heavy lifting

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