Jobs in the United States

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Added 1 min ago
Regional Automation Engineer Manager, R2L/GSF
Amazon
Nashville, TN
As the Regional Automation Engineer Manager, you will lead teams of onsite and regional automation engineers in driving equipment reliability and operational excellence across our…
Added 1 min ago
Senior Controls Integration Engineer, Worldwide Design and Engineering
Amazon
Nashville, TN
WWDE is looking for a Senior Controls Integration Engineer to be part of our global team to deliver the next generation of world-class fulfillment systems. Successful candidates are natural…
Added 1 min ago
PN
Electrical Engineer 3
Pacific Northwest National Laboratory
Nashville, TN
- $122,100 USD / year
The Operational Systems Engineering group within the Earth Systems Science Division seeks a mid-career Electrical Engineer to support research, development, and deployment activities…
Added 1 min ago
Site Reliability Engineer
Highmark Health
Nashville, TN
…device hardening. Assists with network segmentation, access control, and other configuration and monitoring activities whichisolate and to protect clinical and other critical devices.…
Added 1 min ago
EC
Lead Power Systems Controls Engineer
Eaton Corporation
Nashville, TN · Louisville, TN · Memphis, TN
- $97,000 to $143,000 USD / year
…the development, testing, and implementation of power systems control solutions for our customers using PLC’s, HMI’s, Multi-function Protection Relays, and Data Concentrators from all major…
Added 1 min ago
C
Regional Maintenance Manager
CBRE
Nashville, TN
- $200,000 to $210,000 USD / year
…maintaining continuity throughout to provide overall quality control for all…
Added 1 min ago
Advanced Lead Supplier Quality Engineer - Composites
GE Aerospace
Nashville, TN
The Supplier Quality Engineer for Polymer Matrix Composites is an individual who can apply knowledge of RCCA and/or problem solving to lead supplier quality improvement of complex cross…
Added 1 min ago
Quality Engineer (Audit and QA)
NWI Aerostructures
Nashville, TN
Quality Engineer (Audit and QA) Location: Nashville, TN Company: NWI Nashville, LLC Status: Full-time, onsite We are looking for a Quality Engineer (Audit and QA) to join our Quality Team.…
Added 1 min ago
GA
Sr Manufacturing Engineer - Sourced Hardware
GE Aerospace
Nashville, TN
- $136,000 to $181,000 USD / year
The Senior Manufacturing Engineer will manage and coordinate delivery projects within the Supplier Performance & Execution Sourcing Section. You will organize and coordinate…
Added 1 min ago
GA
Sr Manufacturing Engineer - Sourced Hardware
GE Aerospace
Nashville, TN
- $116,000 to $155,000 USD / year
The Senior Manufacturing Engineer will manage and coordinate delivery projects within the Supplier Performance & Execution Sourcing Section. You will organize and coordinate…
Added 1 min ago
GA
Sr Manufacturing Engineer - Sourced Hardware
GE Aerospace
Nashville, TN
- $116,000 to $155,000 USD / year
The Senior Manufacturing Engineer will manage and coordinate delivery projects within the Supplier Performance & Execution Sourcing Section. You will organize and coordinate…
Added 14 mins ago
Senior Flight Test Engineer - Mission Autonomy (UAS - Fury)
Anduril Industries
Costa Mesa, CA
…turns thousands of data streams into a realtime, 3D command and control center. As the world enters an era of strategic competition, Anduril is committed to bringing cutting-edge autonomy,…
Added 14 mins ago
Flight Test Engineer - Mission Autonomy (UAS - Fury)
Anduril Industries
Costa Mesa, CA
…turns thousands of data streams into a realtime, 3D command and control center. As the world enters an era of strategic competition, Anduril is committed to bringing cutting-edge autonomy,…
Added 14 mins ago
Flight Test Engineer - Mission Autonomy
Anduril Industries
Costa Mesa, CA
…turns thousands of data streams into a realtime, 3D command and control center. As the world enters an era of strategic competition, Anduril is committed to bringing cutting-edge autonomy,…
Added 25 mins ago
Design Engineer II
Silicon Laboratories Inc.
United States
As a Digital Design Engineer II you will develop world class, highly integrated, low power, System on a Chip devices to serve the IoT wireless market.
Added 32 mins ago
GA
Sr Manufacturing Engineer - Sourced Hardware
GE Aerospace
Hooksett, NH
- $116,000 to $155,000 USD / year
The Senior Manufacturing Engineer will manage and coordinate delivery projects within the Supplier Performance & Execution Sourcing Section. You will organize and coordinate…
Added 32 mins ago
GA
Sr Manufacturing Engineer 2 – Sourced Hardware
GE Aerospace
Hooksett, NH
- $136,000 to $181,000 USD / year
The Senior Manufacturing Engineer will manage and coordinate delivery projects within the Supplier Performance & Execution Sourcing Section. You will organize and coordinate…
Added 33 mins ago
GA
Sr Manufacturing Engineer - Sourced Hardware
GE Aerospace
Hooksett, NH
- $116,000 to $155,000 USD / year
The Senior Manufacturing Engineer will manage and coordinate delivery projects within the Supplier Performance & Execution Sourcing Section. You will organize and coordinate…
Added 35 mins ago
Kubernetes Engineer - Active TS/SCI with CI Poly
ENS Solutions, LLC
Reston, VA
We are seeking a Sr. Kubernetes Engineer II to join our dynamic team and play a pivotal role in safeguarding our organization's digital assets and sensitive information. The ideal candidate…
Added 36 mins ago
Project Engineer
Apogee Sustainability Limited
Chicago, IL · Houston, TX · Pittsburgh, PA
Energy Drive Systems is a global leader in industrial energy efficiency, delivering Intelligent Motor Control and Energy Efficiency-as-a-Service (EEaaS) solutions to heavy industry. As we…
Added 36 mins ago
Energy Solutions Engineer
Apogee Sustainability Limited
Remote, United States
…reliability and accelerate decarbonisation through advanced motor control and energy optimisation…
Added 40 mins ago
Supervising Senior Automation Engineer I
Stellix
Foxborough, MA
…of existing facilities. The Engineering team provides large project engineering, site engineering and integration engineering services using the DeltaV Automation System. Engineers leverage…
Added 40 mins ago
IT/OT Engineer
Stellix
Foxborough, MA
We are currently looking for a IT/OT Engineer who will participate in all technical aspects the group is responsible for including product development, project engineering and site support.…
Added 40 mins ago
IT/OT Engineer
Stellix
Foxborough, MA
We are currently looking for a IT/OT Engineer III position within our IT/OT managed services team to provide post-project services (such as DCS Platform, OT infrastructure, virtualization,…
Added 40 mins ago
Senior Automation Engineer (Back-End SCADA)
Stellix
Foxborough, MA
…of existing facilities. The Engineering team provides large project engineering, site engineering and integration engineering services using the Ignition and other SCADA systems. Engineers…

CURIA

Principal Engineer

United States

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Job details

Experience: Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Posting language: English
Posted: Nov 4, 2026

Original job description

Principal Engineer – Filling & Lyophilization – United States Build your future at Curia, where our work has the power to save lives. The Principal Engineer will lead equipment engineering for large capital projects in sterile filling and lyophilization to support Curia’s strategic growth. This includes leading network-wide capital execution to expand, modernize, and standardize manufacturing infrastructure. The incumbent will direct the specification, procurement, installation, commissioning, and qualification of advanced aseptic technologies to increase capacity, efficiency, and compliance for drug product programs. This position interfaces with Curia’s network manufacturing sites, client technical teams, and global leadership. The role provides technical oversight, mentorship, and engineering guidance across site-based teams and major capital project teams. Curia is a global contract development and manufacturing organization (CDMO) with over 30 years of experience partnering with pharmaceutical and biotech companies to provide life-saving treatments to patients. At Curia, we are on a mission to advance our customers’ therapies from curiosity to cure and ultimately to improve patients’ lives. We proudly offer

Generous benefit options (eligible first day of employment)
Paid training, vacation and holidays (vacation accrual begins on first day of employment)
Career advancement opportunities
Education reimbursement
401K program with matching contributions
Learning platform
And more!

Responsibilities

Capital Project Execution: Lead filling and lyophilization equipment engineering for major capital projects ($10M–$50M+) from conceptual design through Commissioning, Qualification, and Validation (CQV)
Technical Transfer & Client Support: Drive robust, on-time technical transfers of API and Drug Product (DP) programs, partnering with the Global Program Management Office and site technical operation teams to satisfy client expectations
Equipment Specification & Procurement: Author User Requirement Specifications (URS), drive vendor selection, conduct capital cost estimation, and lead Factory/Site Acceptance Testing (FAT/SAT) for primary equipment (fill lines, isolators, lyos, VHP, capping)
Network Capability & Talent Development: Mentor site-based engineering teams across the Curia network, sharing best practices, upgrading skill sets, and driving technical standardization
Operational Excellence & Continuous Improvement: Partner with sites to troubleshoot complex equipment deviations, increase OEE, reduce cycle times, and execute cost-improvement programs
Vendor & Engineering Firm Management: Oversee external engineering design firms, equipment vendors, and field contractors for filling and lyophilization installations
Regulatory Compliance: Ensure all equipment and system designs comply with cGMP, EU Annex 1 (Contamination Control Strategy), FDA guidance, and global regulatory standards
This job has no direct supervisory responsibilities; serves as a technical lead and matrix manager for project teams and site engineering resources
Travel Requirement: Up to 40% travel, including international travel to plant sites and vendor facilities Education and Experience
Education: BS in Mechanical, Chemical, Electrical, or Biomedical Engineering (or related discipline)
Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Capital Projects: Proven track record leading major capital equipment execution projects exceeding $10M Technical Expertise: Advanced expertise in
Aseptic processing, high-speed sterile filling (vials, syringes, cartridges), and barrier technology (Isolators/RABS)
Lyophilization processes and automated loading/unloading systems (ALUS)
Decontamination systems (VHP / Hydrogen Peroxide Vapor)
Sterilization processes (SIP, Autoclaves, Depyrogenation Tunnels)
Critical Utilities (WFI, Clean Steam, Clean Compressed Air, Process Gases, Cleanrooms, and HVAC)
Commissioning, Qualification, and Validation (CQV / ISPE Baseline Guide approach)
Regulatory & Quality Knowledge: Deep understanding of global pharmaceutical regulations (FDA cGMP, EMA, EU Annex 1, PIC/S) Skills & Capabilities
Analytical & Problem Solving: Demonstrated root-cause analysis skills (e.g., FMEA, 6-Sigma) to address complex process and equipment deviations
Communication & Stakeholder Management: Excellent verbal and written communication skills with experience presenting technical concepts to executive leadership, site teams, and external clients
Computer & Software Skills: Proficient in project management software, CAD systems, CMMS, Trackwise/QMS systems, MS Office Suite (Word, Excel, PowerPoint), and process automation systems (PLC/SCADA/DCS) Other Qualifications & Requirements
Must pass a background check and drug screen
Ability to work in cleanroom environments (Gowning required) Physical Demands & Work Environment
Physical Demands: Regularly required to talk, hear, sit, stand, walk, reach, and lift up to 25–50 lbs
Work Environment: Mix of office environment, active construction sites, and cGMP cleanrooms. Moderate noise level with exposure to moving mechanical parts and industrial chemical/utility systems This job description in no way states or implies that these are the only duties to be performed by the employee(s) incumbent in this position. Employees will be required to follow any other job-related instructions and to perform any other job-related duties requested by any person authorized to give instructions or assignments. All duties and responsibilities are essential functions and requirements and are subject to possible modification to reasonably accommodate individuals with disabilities. To perform this job successfully, the incumbents will possess the skills, aptitudes, and abilities to perform each duty proficiently. Some requirements may exclude individuals who pose a direct threat or significant risk to the health or safety of themselves or others. The requirements listed in this document are the minimum levels of knowledge, skills, or abilities. This document does not create an employment contract, implied or otherwise, other than an “at will” relationship.

Salary range:$120,200-$144,100/year Education, experience, location and tenure may be considered along with internal equity when job offers are extended. We do not accept unsolicited assistance from any headhunters or recruitment firms for any of our job openings. All resumes or profiles submitted by search firms to any employee at Curia, in any form without a valid, signed search agreement by an authorized signatory in place for the specific position, approved by Talent Acquisition, will be deemed the sole property of Curia. No fee will be paid in the event the candidate is hired by Curia because of the unsolicited referral.

All interested applicants must apply online. Please be aware of scammers. Curia will only send offer letters and requests for sensitive personal information from a curiaglobal.com email address. Curia is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Curia is an E-Verify employer.

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More about this job

Skills

Procurement
Regulatory compliance
Program management
Microsoft Office
Estimating
Process improvement
Troubleshoot
Biomedical engineering
Pharmaceutical technology
SIP
HVAC
Pharmaceutical legislation
Problem solving
Root cause analysis
Communication skills
Stakeholder management
Project management
CMMS
Microsoft Word
Microsoft Excel
Microsoft PowerPoint
PLC
SCADA
DCS
Heavy lifting

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