Jobs in the United States

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Added 4 mins ago
Specialist, Pre-Apprenticeship
Foundation for California Community Colleges
Remote, United States
…work-based learning initiatives. This position applies strong project management, coordination, and facilitation skills to ensure high-quality delivery of programs and technical assistance…
Added 5 mins ago
Sr. Technical Program Manager
Sony Interactive Entertainment (SIE)
San Diego, CA
This role is suited for individuals who combine deep Agile, Scrum, and technical program management expertise with systems thinking, technical fluency, executive communication, and the…
Added 7 mins ago
SW
Supervisor, Entertainment | Full-Time | Sesame Place
Sea World LLC
United States
- $22.75 USD / hour
- Full-time
This role is a project-based production supervisor role with duties that oversee the installation, rehearsal, and operation of assigned Entertainment venue/area, including the daily…
Added 7 mins ago
General Manager
Applied Industrial Technologies - PA LLC
Williamsport, PA
…your sales development, strategic planning, administrative and project management skills, but also your coaching and mentoring abilities. Reporting to the Regional Manager, you will lead…
Added 7 mins ago
General Manager
Applied Industrial Technologies, Inc.
Fairmont, WV
…your sales development, strategic planning, administrative and project management skills, but also your coaching and mentoring abilities. Reporting to the Regional Manager, you will lead…
Added 9 mins ago
Director, Engineering Systems Design
Invitrogen Holdings LLC
Pleasanton, CA
We are seeking a Director of Core Engineering & Systems Design to lead systems engineering, integration and hardware engineering across electrical, mechanical and optical disciplines. This…
Added 13 mins ago
Engineer – Combination Product Development, Prefilled Syringe (PFS) Platform
Amgen Inc.
CA
…and coordinates with cross-functional partners. Depending on project assignment, the engineer may lead technical teams or workstreams supporting product development, platform development,…
Added 13 mins ago
Medical Science Liaison-Obesity and Related Conditions-San Jose, CA
Amgen Inc.
CA
Lead and/or participate on project teams that support MSL strategies and tactics as delegated by MSL leadership.
Added 13 mins ago
Medical Science Liaison-Obesity and Related Conditions-West Los Angeles
Amgen Inc.
CA
Lead and/or participate on project teams that support MSL strategies and tactics as delegated by MSL leadership.
Added 14 mins ago
DT
Project Engineering Intern
Daimler Truck North America LLC
Portland, OR
- $21 to $29 USD / hour
DTNA Engineering Platform Management (EPM) is responsible for the project management of major product projects at DTNA, which includes product planning, technical feasibility studies,…
Added 14 mins ago
DD
Digital Transformation Intern
Detroit Diesel Corporation
Detroit, MI
- $21 to $29 USD / hour
Documentation and knowledge management (including AI solutions) - Help write and maintain project and operational documentation (requirements, data flows, application logic, dependencies,…
Added 15 mins ago
Technical Training Coordinator - 1st Shift (6:00am - 4:30pm)
Thermo Fisher Scientific
Greenville, NC
Excellent organizational and project management skills
Added 15 mins ago
Director, Engineering Systems Design
Thermo Fisher Scientific
Pleasanton, CA
We are seeking a Director of Core Engineering & Systems Design to lead systems engineering, integration and hardware engineering across electrical, mechanical and optical disciplines. This…
Added 17 mins ago
Clinical Adoption Specialist III – Outpatient Pharmacy (Federal Oracle Health Implementation)
S&P Consultants, Inc.
Remote, United States
Capture organizational change management items, ensuring mitigation of change impacts
Added 18 mins ago
EI
Area Leader Trainee Intern
Eleven Inc
Huntington Beach, CA · Santa Ana, CA
- $7.5 to $18.75 USD / hour
The Field Operations Internship Program is a paid summer internship, that immerses interns in the fast-paced work environment of 7-Eleven. The program will consist of multiple segments that…
Added 18 mins ago
RH
Human Resources (HR) Business Partner
Robert Half
Morgan Hill, CA
- $150,000 to $170,000 USD / year
Strong organizational and project management abilities with the capacity to manage competing priorities effectively.
Added 18 mins ago
WD
Estimator
Walt Disney Parks and Resorts U.S., Inc.
Lake Buena Vista, FL
- $92,400 to $123,800 USD / year
The Estimator will support projects with the Facility Asset Management team (FAM). This position produces several levels of construction project estimates, with a heavy concentration on…
Added 18 mins ago
DH
Manager of Learning & Talent - Aulani, A Disney Resort & Spa ($128,700 - $157,100)
DVC Hawaii Management Company, LLC
Kapolei, HI
- $128,700 to $157,100 USD / year
Lead project management for learning initiatives from planning and analysis through delivery and sustainment.
Added 18 mins ago
Product Owner
INSPYR Solutions
Medellin
2–4 years of experience in product ownership, business analysis, project management, or software development supporting enterprise products and solutions.
Added 20 mins ago
Solution Integration & Implementation Manager
Amdocs
Plano, TX · Plano
Delivery & program management: own schedules, site counts, forecasts, and blockers across 11+ programs spanning Macro, MOD, NSD, AAV Vanguard, Cabinet Consolidation. Build GC crew ramp…
Added 20 mins ago
Warehouse Team Leader
United States
The Warehouse Team Leader is responsible for managing product flow throughout the store, communication with management on product levels, distribution of product between stores, and…
Added 25 mins ago
INSTRUMENTATION ELECTRIC & CONTROL SPECIALIST
City of Amarillo
United States
…and programming. Occasionally, may be called upon to act as lead man for other Electronic Instrumentation Technician’s, electricians, or for one or more mechanics, or utility workers on a…
Added 26 mins ago
CE
Construction Foreman - Dry Utilities
Carney Engineering Construction
Artesia, CA
- $47.45 to $61.05 USD / hour
Coordinate equipment, crew, and material needs with the project management team.
Added 29 mins ago
A
Construction Superintendent
Actalent
Powell, OH
- $40 to $55 USD / hour
…ground-up boutique hotel development in Hocking Hills, Ohio. The project consists of five new buildings constructed from the ground up, requiring a superintendent who can simultaneously…
Added 31 mins ago
Commercial Program Manager
Industrial Electric Manufacturing
Jacksonville, FL · Fremont, CA
5+ years of program or project management experience in a manufacturing or enterprise client-facing role with annualized volume exceeding $10 million.

CURIA

Principal Engineer

United States

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Job details

Experience: Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Posting language: English
Posted: Nov 4, 2026

Original job description

Principal Engineer – Filling & Lyophilization – United States Build your future at Curia, where our work has the power to save lives. The Principal Engineer will lead equipment engineering for large capital projects in sterile filling and lyophilization to support Curia’s strategic growth. This includes leading network-wide capital execution to expand, modernize, and standardize manufacturing infrastructure. The incumbent will direct the specification, procurement, installation, commissioning, and qualification of advanced aseptic technologies to increase capacity, efficiency, and compliance for drug product programs. This position interfaces with Curia’s network manufacturing sites, client technical teams, and global leadership. The role provides technical oversight, mentorship, and engineering guidance across site-based teams and major capital project teams. Curia is a global contract development and manufacturing organization (CDMO) with over 30 years of experience partnering with pharmaceutical and biotech companies to provide life-saving treatments to patients. At Curia, we are on a mission to advance our customers’ therapies from curiosity to cure and ultimately to improve patients’ lives. We proudly offer

Generous benefit options (eligible first day of employment)
Paid training, vacation and holidays (vacation accrual begins on first day of employment)
Career advancement opportunities
Education reimbursement
401K program with matching contributions
Learning platform
And more!

Responsibilities

Capital Project Execution: Lead filling and lyophilization equipment engineering for major capital projects ($10M–$50M+) from conceptual design through Commissioning, Qualification, and Validation (CQV)
Technical Transfer & Client Support: Drive robust, on-time technical transfers of API and Drug Product (DP) programs, partnering with the Global Program Management Office and site technical operation teams to satisfy client expectations
Equipment Specification & Procurement: Author User Requirement Specifications (URS), drive vendor selection, conduct capital cost estimation, and lead Factory/Site Acceptance Testing (FAT/SAT) for primary equipment (fill lines, isolators, lyos, VHP, capping)
Network Capability & Talent Development: Mentor site-based engineering teams across the Curia network, sharing best practices, upgrading skill sets, and driving technical standardization
Operational Excellence & Continuous Improvement: Partner with sites to troubleshoot complex equipment deviations, increase OEE, reduce cycle times, and execute cost-improvement programs
Vendor & Engineering Firm Management: Oversee external engineering design firms, equipment vendors, and field contractors for filling and lyophilization installations
Regulatory Compliance: Ensure all equipment and system designs comply with cGMP, EU Annex 1 (Contamination Control Strategy), FDA guidance, and global regulatory standards
This job has no direct supervisory responsibilities; serves as a technical lead and matrix manager for project teams and site engineering resources
Travel Requirement: Up to 40% travel, including international travel to plant sites and vendor facilities Education and Experience
Education: BS in Mechanical, Chemical, Electrical, or Biomedical Engineering (or related discipline)
Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Capital Projects: Proven track record leading major capital equipment execution projects exceeding $10M Technical Expertise: Advanced expertise in
Aseptic processing, high-speed sterile filling (vials, syringes, cartridges), and barrier technology (Isolators/RABS)
Lyophilization processes and automated loading/unloading systems (ALUS)
Decontamination systems (VHP / Hydrogen Peroxide Vapor)
Sterilization processes (SIP, Autoclaves, Depyrogenation Tunnels)
Critical Utilities (WFI, Clean Steam, Clean Compressed Air, Process Gases, Cleanrooms, and HVAC)
Commissioning, Qualification, and Validation (CQV / ISPE Baseline Guide approach)
Regulatory & Quality Knowledge: Deep understanding of global pharmaceutical regulations (FDA cGMP, EMA, EU Annex 1, PIC/S) Skills & Capabilities
Analytical & Problem Solving: Demonstrated root-cause analysis skills (e.g., FMEA, 6-Sigma) to address complex process and equipment deviations
Communication & Stakeholder Management: Excellent verbal and written communication skills with experience presenting technical concepts to executive leadership, site teams, and external clients
Computer & Software Skills: Proficient in project management software, CAD systems, CMMS, Trackwise/QMS systems, MS Office Suite (Word, Excel, PowerPoint), and process automation systems (PLC/SCADA/DCS) Other Qualifications & Requirements
Must pass a background check and drug screen
Ability to work in cleanroom environments (Gowning required) Physical Demands & Work Environment
Physical Demands: Regularly required to talk, hear, sit, stand, walk, reach, and lift up to 25–50 lbs
Work Environment: Mix of office environment, active construction sites, and cGMP cleanrooms. Moderate noise level with exposure to moving mechanical parts and industrial chemical/utility systems This job description in no way states or implies that these are the only duties to be performed by the employee(s) incumbent in this position. Employees will be required to follow any other job-related instructions and to perform any other job-related duties requested by any person authorized to give instructions or assignments. All duties and responsibilities are essential functions and requirements and are subject to possible modification to reasonably accommodate individuals with disabilities. To perform this job successfully, the incumbents will possess the skills, aptitudes, and abilities to perform each duty proficiently. Some requirements may exclude individuals who pose a direct threat or significant risk to the health or safety of themselves or others. The requirements listed in this document are the minimum levels of knowledge, skills, or abilities. This document does not create an employment contract, implied or otherwise, other than an “at will” relationship.

Salary range:$120,200-$144,100/year Education, experience, location and tenure may be considered along with internal equity when job offers are extended. We do not accept unsolicited assistance from any headhunters or recruitment firms for any of our job openings. All resumes or profiles submitted by search firms to any employee at Curia, in any form without a valid, signed search agreement by an authorized signatory in place for the specific position, approved by Talent Acquisition, will be deemed the sole property of Curia. No fee will be paid in the event the candidate is hired by Curia because of the unsolicited referral.

All interested applicants must apply online. Please be aware of scammers. Curia will only send offer letters and requests for sensitive personal information from a curiaglobal.com email address. Curia is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Curia is an E-Verify employer.

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More about this job

Skills

Procurement
Regulatory compliance
Program management
Microsoft Office
Estimating
Process improvement
Troubleshoot
Biomedical engineering
Pharmaceutical technology
SIP
HVAC
Pharmaceutical legislation
Problem solving
Root cause analysis
Communication skills
Stakeholder management
Project management
CMMS
Microsoft Word
Microsoft Excel
Microsoft PowerPoint
PLC
SCADA
DCS
Heavy lifting

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