Jobs in the United States

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Added 1 min ago
Sr. Systems Engineer II
Proconex
Royersford, PA
The Senior Systems Engineer II applies expert-level process control and automation knowledge to architect solutions, optimize manufacturing operations, mentor engineers, improve engineering…
Added 1 min ago
Software Dev Engineer I, Security Platform
Twitch Interactive, Inc.
Seattle, WA · Irvine, CA · San Francisco, CA
…explore our Interviewing Guide to learn how to ace our interview…
Added 2 mins ago
Systems & Application Engineer
Elite ISI
Los Angeles, CA
Are you an experienced Systems Engineer who enjoys solving complex technical challenges, implementing innovative solutions, and seeing projects through from start to finish?
Added 3 mins ago
SN
Director of Information Security Engineering
Southern New Hampshire University
Remote, United States
- $129,057 to $206,531 USD / year
Evaluate, select, and oversee implementation of security technologies with disciplined focus on reducing complexity, improving efficacy, and enabling automation.
Added 4 mins ago
UI
Controls Engineer Working Lead
Uniloy INC
Tecumseh, MI
- $130,000 to $150,000 USD / year
Experience with advanced process control a plus (internal model control, feed forward, autotuning of PID parameters)
Added 6 mins ago
C
Forward Deployed Engineer
Caylent
United States
- $136,000 to $216,000 USD / year
Hands-on experience in one or more of: LLM application development, cloud-native development, backend engineering, or business automation tooling
Added 7 mins ago
TM
Manufacturing Engineering Manager
thyssenkrupp Materials NA, Inc.
United States
- $115,000 to $150,000 USD / year
Lead, coach, and develop Manufacturing Engineers, Process Engineers, and Engineering Technicians.
Added 7 mins ago
Intelligent Automation Engineer
BrightSpring Health Services
LOUISVILLE, KY
We’re seeking an Intelligent Automation Engineer with strong hands-on expertise in UiPath, Microsoft Power Platform, Power BI, Copilot Studio, and Agentic AI. This role will design scalable…
Added 9 mins ago
Infrastructure Software Engineer II (Remote - US)
BNSF Railway
United States
Build and operate infrastructure as code, automation, and observability tools and services
Added 9 mins ago
Systems Engineer, Test Automation
Peraton
Annapolis Junction, MD
This position is listed as a System Engineer; however, this role supports Test Automation.
Added 10 mins ago
Engineer, Drive Unit Test & Validation
Lucid Motors
Newark, CA
As a Test and Validation Engineer, you will take responsibility for the development and execution of automated test systems for drive units and powertrain components. Based on your…
Added 11 mins ago
BMS / EPMS Controls Lead
Cerebras Systems
Remote, United States
Cerebras is expanding the data center infrastructure that supports its AI systems. The BMS / EPMS Controls Engineer will define and deliver the building automation and electrical power…
Added 12 mins ago
3K
Engineer, Primary Container Testing, Characterization & Qualification - Biopharma/Medical Device - (JP16093)
3 Key Consulting
Thousand Oaks, CA
- $40 to $46 USD / hour
…project requirements into executable protocols and reports. The engineer will also support equipment evaluations, troubleshooting activities, laboratory automation initiatives, and…
Added 13 mins ago
Subject Matter Expert (Manufacturing Engineer) - Optics Polishing
Coherent Corp. US
Budd Lake, NJ
Job Summary: We are seeking an experienced Crystal Optics Fabrication, Polishing, and Automation Subject Matter Expert for our Budd Lake, NJ location. This role will provide technical…
Added 16 mins ago
Subject Matter Expert (Manufacturing Engineer) - Optics Polishing
Coherent Corp. US
Budd Lake, NJ
Job Summary: We are seeking an experienced Crystal Optics Fabrication, Polishing, and Automation Subject Matter Expert for our Budd Lake, NJ location. This role will provide technical…
Added 16 mins ago
Sr Lead Infrastructure Engineer - Network Access Control Sr Engineer
JPMC page
Columbus, OH · OH
As a Senior Lead Infrastructure Engineer at JPMorgan Chase within the Corporate Sector – Enterprise Network team, you exhibit both depth and breadth of knowledge regarding software,…
Added 16 mins ago
Senior Quality Automation Engineer
Wolters Kluwer DXG U.S., Inc.
Waltham, MA
Help improve the quality and reliability of GainsKeeper application, by building practical test automation for investment and brokerage workflows. You’ll work with engineering and product…
Added 16 mins ago
Lead Product Architect
Wolters Kluwer DXG U.S., Inc.
Coppell, TX
Partner with engineering teams to create specifications that can be consumed by AI coding agents and automation platforms.
Added 17 mins ago
Senior SailPoint Administrator
BCBSM, Inc.
Eagan, MN
Identify opportunities to improve operational efficiency through automation.
Added 18 mins ago
Lead Software Engineer-Marketing Technology
AAPC
Remote, United States
AAPC seeks a hands-on lead software engineer to help build and evolve the customer-facing digital products, e-commerce experiences, and marketing technology that take people from discovery…
Added 18 mins ago
AI/ML Automation Engineer/Developer (Jr, Mid and Sr.)
Parsons Technical Services, Inc.
MD
Parsons is growing its team of AI/ML Automation Engineers/Developers (at several levels) to support upcoming mission-critical cybersecurity work. If you enjoy performing cutting-edge…
Added 20 mins ago
UG
Software Engineer (Full Stack Developer) - Remote
UnitedHealth Group
Austin, TX
- $72,800 to $130,000 USD / year
We are seeking a highly motivated Software Engineer (Full Stack Developer) to design, develop, and support modern enterprise web applications. In this role, you will work across the full…
Added 21 mins ago
Greenfield Manager, Startups
Vercel
NY · San Francisco, CA
…to build a foundation for adoption and expansion. By using automation and AI to maximize your team's impact, you'll turn wins into repeatable playbooks across the startup…
Added 24 mins ago
Electronic Security Engineer
Wittenbach Business Systems, LLC
Remote, United States
Since 1974, Wittenbach has been a leading provider of innovative cash automation and security solutions for financial institutions. Our commitment to customer satisfaction and delivering…
Added 25 mins ago
Lead Value Engineer - CGPR
Celonis
NY
We are looking for a Lead Value Engineer, Consumer Packaged Goods (CPG) - an industry expert who can bridge the gap between technical process mining, AI-driven automation, and strategic…

CURIA

Principal Engineer

United States

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Job details

Experience: Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Posting language: English
Posted: Nov 4, 2026

Original job description

Principal Engineer – Filling & Lyophilization – United States Build your future at Curia, where our work has the power to save lives. The Principal Engineer will lead equipment engineering for large capital projects in sterile filling and lyophilization to support Curia’s strategic growth. This includes leading network-wide capital execution to expand, modernize, and standardize manufacturing infrastructure. The incumbent will direct the specification, procurement, installation, commissioning, and qualification of advanced aseptic technologies to increase capacity, efficiency, and compliance for drug product programs. This position interfaces with Curia’s network manufacturing sites, client technical teams, and global leadership. The role provides technical oversight, mentorship, and engineering guidance across site-based teams and major capital project teams. Curia is a global contract development and manufacturing organization (CDMO) with over 30 years of experience partnering with pharmaceutical and biotech companies to provide life-saving treatments to patients. At Curia, we are on a mission to advance our customers’ therapies from curiosity to cure and ultimately to improve patients’ lives. We proudly offer

Generous benefit options (eligible first day of employment)
Paid training, vacation and holidays (vacation accrual begins on first day of employment)
Career advancement opportunities
Education reimbursement
401K program with matching contributions
Learning platform
And more!

Responsibilities

Capital Project Execution: Lead filling and lyophilization equipment engineering for major capital projects ($10M–$50M+) from conceptual design through Commissioning, Qualification, and Validation (CQV)
Technical Transfer & Client Support: Drive robust, on-time technical transfers of API and Drug Product (DP) programs, partnering with the Global Program Management Office and site technical operation teams to satisfy client expectations
Equipment Specification & Procurement: Author User Requirement Specifications (URS), drive vendor selection, conduct capital cost estimation, and lead Factory/Site Acceptance Testing (FAT/SAT) for primary equipment (fill lines, isolators, lyos, VHP, capping)
Network Capability & Talent Development: Mentor site-based engineering teams across the Curia network, sharing best practices, upgrading skill sets, and driving technical standardization
Operational Excellence & Continuous Improvement: Partner with sites to troubleshoot complex equipment deviations, increase OEE, reduce cycle times, and execute cost-improvement programs
Vendor & Engineering Firm Management: Oversee external engineering design firms, equipment vendors, and field contractors for filling and lyophilization installations
Regulatory Compliance: Ensure all equipment and system designs comply with cGMP, EU Annex 1 (Contamination Control Strategy), FDA guidance, and global regulatory standards
This job has no direct supervisory responsibilities; serves as a technical lead and matrix manager for project teams and site engineering resources
Travel Requirement: Up to 40% travel, including international travel to plant sites and vendor facilities Education and Experience
Education: BS in Mechanical, Chemical, Electrical, or Biomedical Engineering (or related discipline)
Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Capital Projects: Proven track record leading major capital equipment execution projects exceeding $10M Technical Expertise: Advanced expertise in
Aseptic processing, high-speed sterile filling (vials, syringes, cartridges), and barrier technology (Isolators/RABS)
Lyophilization processes and automated loading/unloading systems (ALUS)
Decontamination systems (VHP / Hydrogen Peroxide Vapor)
Sterilization processes (SIP, Autoclaves, Depyrogenation Tunnels)
Critical Utilities (WFI, Clean Steam, Clean Compressed Air, Process Gases, Cleanrooms, and HVAC)
Commissioning, Qualification, and Validation (CQV / ISPE Baseline Guide approach)
Regulatory & Quality Knowledge: Deep understanding of global pharmaceutical regulations (FDA cGMP, EMA, EU Annex 1, PIC/S) Skills & Capabilities
Analytical & Problem Solving: Demonstrated root-cause analysis skills (e.g., FMEA, 6-Sigma) to address complex process and equipment deviations
Communication & Stakeholder Management: Excellent verbal and written communication skills with experience presenting technical concepts to executive leadership, site teams, and external clients
Computer & Software Skills: Proficient in project management software, CAD systems, CMMS, Trackwise/QMS systems, MS Office Suite (Word, Excel, PowerPoint), and process automation systems (PLC/SCADA/DCS) Other Qualifications & Requirements
Must pass a background check and drug screen
Ability to work in cleanroom environments (Gowning required) Physical Demands & Work Environment
Physical Demands: Regularly required to talk, hear, sit, stand, walk, reach, and lift up to 25–50 lbs
Work Environment: Mix of office environment, active construction sites, and cGMP cleanrooms. Moderate noise level with exposure to moving mechanical parts and industrial chemical/utility systems This job description in no way states or implies that these are the only duties to be performed by the employee(s) incumbent in this position. Employees will be required to follow any other job-related instructions and to perform any other job-related duties requested by any person authorized to give instructions or assignments. All duties and responsibilities are essential functions and requirements and are subject to possible modification to reasonably accommodate individuals with disabilities. To perform this job successfully, the incumbents will possess the skills, aptitudes, and abilities to perform each duty proficiently. Some requirements may exclude individuals who pose a direct threat or significant risk to the health or safety of themselves or others. The requirements listed in this document are the minimum levels of knowledge, skills, or abilities. This document does not create an employment contract, implied or otherwise, other than an “at will” relationship.

Salary range:$120,200-$144,100/year Education, experience, location and tenure may be considered along with internal equity when job offers are extended. We do not accept unsolicited assistance from any headhunters or recruitment firms for any of our job openings. All resumes or profiles submitted by search firms to any employee at Curia, in any form without a valid, signed search agreement by an authorized signatory in place for the specific position, approved by Talent Acquisition, will be deemed the sole property of Curia. No fee will be paid in the event the candidate is hired by Curia because of the unsolicited referral.

All interested applicants must apply online. Please be aware of scammers. Curia will only send offer letters and requests for sensitive personal information from a curiaglobal.com email address. Curia is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Curia is an E-Verify employer.

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More about this job

Skills

Procurement
Regulatory compliance
Program management
Microsoft Office
Estimating
Process improvement
Troubleshoot
Biomedical engineering
Pharmaceutical technology
SIP
HVAC
Pharmaceutical legislation
Problem solving
Root cause analysis
Communication skills
Stakeholder management
Project management
CMMS
Microsoft Word
Microsoft Excel
Microsoft PowerPoint
PLC
SCADA
DCS
Heavy lifting

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