Jobs in the United States

25+ jobs

Save this search

Added 2 mins ago
CO
Public Works Director
City of Kilgore
Kilgore, TX
- $114,664 to $159,768 USD / year
Serves as the principal advisor to the City on Public Works programs and technical issues; provides leadership, direction, and guidance in operational strategies and priorities; coordinates…
Added 6 mins ago
Senior Program Manager
Akima, LLC
Camp H M Smith, HI
ASE is seeking a highly qualified and experienced Senior Program Manager to provide overall leadership, management, and operational oversight of our Information Technology Service Support…
Added 10 mins ago
Manager, Business Risk Management
Janssen Research & Development, LLC Legal Entity
Raritan, NJ
We are searching for the best talent for Manager, Business Risk Management .
Added 14 mins ago
Cook
Taos Municipal Schools
Taos, NM
Reports to: School Principal FLSA Status: Non-Exempt
Added 33 mins ago
26-27 ADM Human Resources Director
Midway ISD (ESC 12)
TX
…internal controls, and uses data to recommend improvements in program administration and employee service. Implement legally sound and effective HR management programs, policies, and…
Added 1 hour ago
Hyperconverged Infrastructure Engineer
Koniag Government Services
Washington, DC
Koniag Technology Solutions, inc a Koniag Government Services company, is seeking a Program Manager with a Secret Security clearance to support KTS and our government customer in…
Added 1 hour ago
Program Manager
Koniag Government Services
Washington, DC
…is seeking an experienced, motivated, and customer-oriented Program Manager to lead a team of engineers supporting cloud and data center engineering projects for the Department of State's…
Added 1 hour ago
Assistant Program Manager
Koniag Government Services
Falls Church, VA
The Deputy Program Manager (DPM) supports the Program Manager (PM) in the overall leadership, execution, and administration of the contract. The DPM serves as the PM’s principal deputy and…
Added 1 hour ago
Junior Project Manager
Koniag Government Services
Fort Belvoir, VA
Koniag IT Systems, a Koniag Government Services (KGS) company, is seeking a Junior Project Manager to support a Federal defense customer. This role supports secure and reliable enterprise…
Added 1 hour ago
KOAM COMSEC Specialist
Koniag Government Services
Fort Belvoir, VA
Program, key, troubleshoot, and maintain KG-250, KG-175, KG-75, KIV-7, Secure Terminal Equipment (STE), and supported encrypted communications equipment.
Added 1 hour ago
Senior Program Manager
Koniag Government Services
Fort Belvoir, VA
Koniag IT Systems, a Koniag Government Services (KGS) company, is seeking a Senior Program Manager to support a federal defense customer. This role supports secure and reliable enterprise…
Added 1 hour ago
FSO Manager
Koniag Government Services
Linthicum Heights, MD
Koniag Government Services is seeking a contingent FSO Manager for the DC3 TABO S&F Support program. The position supports security task leadership, personnel clearance processing, physical…
Added 1 hour ago
Inventory Management Specialist
Koniag Government Services
Linthicum Heights, MD
Koniag Government Services is seeking a contingent Inventory Management Specialist for the DC3 TABO S&F Support program. The position supports logistics, material accountability, inventory…
Added 1 hour ago
Finance Manager
Koniag Government Services
Linthicum Heights, MD
Koniag Government Services is seeking a contingent Finance Manager for the DC3 TABO S&F Support program. The role supports financial management, PPBE-related analysis, resource projection,…
Added 1 hour ago
ServiceNow Administrator/Developer
Koniag Government Services
Nashville, TN
…maintenance of the ServiceNow platform supporting Call Center operations. This individual will work closely with the Call Center Operations Manager, program leadership, and end users to…
Added 1 hour ago
Service Level/Capacity Manager
Koniag Government Services
Washington, DC
The Service Level & Capacity Manager operates within a mature ITIL 4-aligned IT Service Management (ITSM) practice and works in close coordination with the Program Manager, Incident…
Added 1 hour ago
Call Center Supervisor (Swing shift)
Koniag Government Services
Nashville, TN
…supervision of a team of Call Center agents, ensuring that day-to-day operations run smoothly and that service delivery standards, performance metrics, and customer satisfaction goals are…
Added 1 hour ago
Privacy and Controlled Unclassified Information Lead
Koniag Government Services
Washington, DC
Principal responsibilities will include but are not limited to:
Added 1 hour ago
ServiceNow Administrator
Koniag Government Services
Nashville, TN
…maintenance of the ServiceNow platform supporting Call Center operations. This individual will work closely with the ServiceNow Administrator/Developer, Call Center Operations Manager,…
Added 1 hour ago
Senior Security Manager
Koniag Government Services
Smyrna, GA
Koniag IT Systems, a Koniag Government Services company, is seeking an experienced Senior Security Manager to oversee Cybersecurity Service Operations (CSO) and serve as the single point…
Added 1 hour ago
Quality Control/Quality Assurance (QC/QA) Manager
Koniag Government Services
Arlington, VA
The QC/QA Manager will serve as the senior quality authority responsible for all aspects of quality control and quality assurance programs supporting government facility operations and…
Added 1 hour ago
Quality & Safety Manager
Koniag Government Services
Arlington, VA
Koniag Operations Services, a Koniag Government Services company, is seeking an experienced Quality & Safety Manager to lead comprehensive quality control and safety programs at critical…
Added 1 hour ago
Project Manager
Koniag Government Services
Fort Bliss, TX
Arlluk Technology Solutions seeking an experienced Project Manager to serve in a Working Leader role supporting IT services for a major government client. This position requires hands-on…
Added 1 hour ago
Project Manager
Koniag Government Services
White Sands Missile Range, NM
Arlluk Technology Solutions, LLC seeking an experienced Project Manager to serve in a Working Leader role supporting IT services for a major government client. This position requires…
Added 1 hour ago
Program Manager
Koniag Government Services
Aberdeen, MD
Koniag IT Systems is seeking a highly experienced Program Manager to lead IT support services for a Defense government client. The ideal candidate will provide strategic leadership for IT…

CURIA

Principal Engineer

United States

Apply About employer

Applications open in a new tab.

Job details

Experience: Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Posting language: English
Posted: Nov 4, 2026

Original job description

Principal Engineer – Filling & Lyophilization – United States Build your future at Curia, where our work has the power to save lives. The Principal Engineer will lead equipment engineering for large capital projects in sterile filling and lyophilization to support Curia’s strategic growth. This includes leading network-wide capital execution to expand, modernize, and standardize manufacturing infrastructure. The incumbent will direct the specification, procurement, installation, commissioning, and qualification of advanced aseptic technologies to increase capacity, efficiency, and compliance for drug product programs. This position interfaces with Curia’s network manufacturing sites, client technical teams, and global leadership. The role provides technical oversight, mentorship, and engineering guidance across site-based teams and major capital project teams. Curia is a global contract development and manufacturing organization (CDMO) with over 30 years of experience partnering with pharmaceutical and biotech companies to provide life-saving treatments to patients. At Curia, we are on a mission to advance our customers’ therapies from curiosity to cure and ultimately to improve patients’ lives. We proudly offer

Generous benefit options (eligible first day of employment)
Paid training, vacation and holidays (vacation accrual begins on first day of employment)
Career advancement opportunities
Education reimbursement
401K program with matching contributions
Learning platform
And more!

Responsibilities

Capital Project Execution: Lead filling and lyophilization equipment engineering for major capital projects ($10M–$50M+) from conceptual design through Commissioning, Qualification, and Validation (CQV)
Technical Transfer & Client Support: Drive robust, on-time technical transfers of API and Drug Product (DP) programs, partnering with the Global Program Management Office and site technical operation teams to satisfy client expectations
Equipment Specification & Procurement: Author User Requirement Specifications (URS), drive vendor selection, conduct capital cost estimation, and lead Factory/Site Acceptance Testing (FAT/SAT) for primary equipment (fill lines, isolators, lyos, VHP, capping)
Network Capability & Talent Development: Mentor site-based engineering teams across the Curia network, sharing best practices, upgrading skill sets, and driving technical standardization
Operational Excellence & Continuous Improvement: Partner with sites to troubleshoot complex equipment deviations, increase OEE, reduce cycle times, and execute cost-improvement programs
Vendor & Engineering Firm Management: Oversee external engineering design firms, equipment vendors, and field contractors for filling and lyophilization installations
Regulatory Compliance: Ensure all equipment and system designs comply with cGMP, EU Annex 1 (Contamination Control Strategy), FDA guidance, and global regulatory standards
This job has no direct supervisory responsibilities; serves as a technical lead and matrix manager for project teams and site engineering resources
Travel Requirement: Up to 40% travel, including international travel to plant sites and vendor facilities Education and Experience
Education: BS in Mechanical, Chemical, Electrical, or Biomedical Engineering (or related discipline)
Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Capital Projects: Proven track record leading major capital equipment execution projects exceeding $10M Technical Expertise: Advanced expertise in
Aseptic processing, high-speed sterile filling (vials, syringes, cartridges), and barrier technology (Isolators/RABS)
Lyophilization processes and automated loading/unloading systems (ALUS)
Decontamination systems (VHP / Hydrogen Peroxide Vapor)
Sterilization processes (SIP, Autoclaves, Depyrogenation Tunnels)
Critical Utilities (WFI, Clean Steam, Clean Compressed Air, Process Gases, Cleanrooms, and HVAC)
Commissioning, Qualification, and Validation (CQV / ISPE Baseline Guide approach)
Regulatory & Quality Knowledge: Deep understanding of global pharmaceutical regulations (FDA cGMP, EMA, EU Annex 1, PIC/S) Skills & Capabilities
Analytical & Problem Solving: Demonstrated root-cause analysis skills (e.g., FMEA, 6-Sigma) to address complex process and equipment deviations
Communication & Stakeholder Management: Excellent verbal and written communication skills with experience presenting technical concepts to executive leadership, site teams, and external clients
Computer & Software Skills: Proficient in project management software, CAD systems, CMMS, Trackwise/QMS systems, MS Office Suite (Word, Excel, PowerPoint), and process automation systems (PLC/SCADA/DCS) Other Qualifications & Requirements
Must pass a background check and drug screen
Ability to work in cleanroom environments (Gowning required) Physical Demands & Work Environment
Physical Demands: Regularly required to talk, hear, sit, stand, walk, reach, and lift up to 25–50 lbs
Work Environment: Mix of office environment, active construction sites, and cGMP cleanrooms. Moderate noise level with exposure to moving mechanical parts and industrial chemical/utility systems This job description in no way states or implies that these are the only duties to be performed by the employee(s) incumbent in this position. Employees will be required to follow any other job-related instructions and to perform any other job-related duties requested by any person authorized to give instructions or assignments. All duties and responsibilities are essential functions and requirements and are subject to possible modification to reasonably accommodate individuals with disabilities. To perform this job successfully, the incumbents will possess the skills, aptitudes, and abilities to perform each duty proficiently. Some requirements may exclude individuals who pose a direct threat or significant risk to the health or safety of themselves or others. The requirements listed in this document are the minimum levels of knowledge, skills, or abilities. This document does not create an employment contract, implied or otherwise, other than an “at will” relationship.

Salary range:$120,200-$144,100/year Education, experience, location and tenure may be considered along with internal equity when job offers are extended. We do not accept unsolicited assistance from any headhunters or recruitment firms for any of our job openings. All resumes or profiles submitted by search firms to any employee at Curia, in any form without a valid, signed search agreement by an authorized signatory in place for the specific position, approved by Talent Acquisition, will be deemed the sole property of Curia. No fee will be paid in the event the candidate is hired by Curia because of the unsolicited referral.

All interested applicants must apply online. Please be aware of scammers. Curia will only send offer letters and requests for sensitive personal information from a curiaglobal.com email address. Curia is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Curia is an E-Verify employer.

Apply About employer

More about this job

Skills

Procurement
Regulatory compliance
Program management
Microsoft Office
Estimating
Process improvement
Troubleshoot
Biomedical engineering
Pharmaceutical technology
SIP
HVAC
Pharmaceutical legislation
Problem solving
Root cause analysis
Communication skills
Stakeholder management
Project management
CMMS
Microsoft Word
Microsoft Excel
Microsoft PowerPoint
PLC
SCADA
DCS
Heavy lifting

Report this job