Jobs in the United States

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Project Manager-Multiuse Facility Construction
Turner & Townsend
Columbus, OH
…requirements, cost estimates & budget, work plan schedule & milestones, quality control, and risk…
Added just now
Project Manager-Multiuse Facility Construction
Turner & Townsend
Syracuse, NY
…requirements, cost estimates & budget, work plan schedule & milestones, quality control, and risk…
Added just now
Project Manager-Multiuse Facility Construction
Turner & Townsend
Pittsburgh, PA
…requirements, cost estimates & budget, work plan schedule & milestones, quality control, and risk…
Added 2 mins ago
Data Center Construction Manager (El Paso, TX)
Southern Staffing Group
El Paso, TX
Southern Staffing Group is hiring a Data Center Construction Manager to lead a two-year, multi-building data center build near El Paso, paying $150,000–$170,000 plus a 10% annual bonus.
Added 2 mins ago
Data Center Construction Manager (Abilene, TX)
Southern Staffing Group
Abilene, TX
Southern Staffing Group is hiring a Data Center Construction Manager to lead a long-term, multi-building data center build Abilene, paying $150,000–$170,000 plus a 10% annual bonus.
Added 2 mins ago
Senior MEP Manager
Brasfield & Gorrie, LLC
Raleigh, NC
Brasﬁeld & Gorrie is seeking a Senior MEP Manager to support the planning, coordinating, and construction of mechanical, electrical, and plumbing (MEP) systems on large, complex projects.…
Added 2 mins ago
R&I Independence Assessments CoE Specialist (Senior Manager)
PwC
Saint Louis, MO
As a R&I Independence Assessments CoE Specialist (Senior Manager) you will lead enterprise risk management work focused on independence assessments, regulatory compliance, and the review of…
Added 2 mins ago
R&I Independence Assessments CoE Specialist (Senior Manager)
PwC
Kansas City, MO
As a R&I Independence Assessments CoE Specialist (Senior Manager) you will lead enterprise risk management work focused on independence assessments, regulatory compliance, and the review of…
Added 3 mins ago
Equipment Coordinator
Rising Edge Group
Ellsinore, MO
…throughout the U.S. Division. Working closely with the Fleet Manager, this position supports day-to-day fleet and equipment operations, asset planning, maintenance programs, rental…
Added 5 mins ago
Cyber Operate Manager - Identity Security Architect & Product Engineering
Deloitte
Kansas City, MO
Join Deloitte as a Lead Managed Services Engineer II and help design, engineer, and deploy identity security capabilities across enterprise environments. You will advance attack path…
Added 5 mins ago
Cyber Operate Manager - Identity Security Architect & Product Engineering
Deloitte
Saint Louis, MO
Join Deloitte as a Lead Managed Services Engineer II and help design, engineer, and deploy identity security capabilities across enterprise environments. You will advance attack path…
Added 5 mins ago
Bridge Inspection Supervisor
Department of Transportation
Missoula, MT · Kalispell, MT
The Montana Department of Transportation (MDT) is recruiting for an Area Bridge Inspection Manager. The Area Bridge Inspection Manager directs and oversees the bridge inspection program for…
Added 6 mins ago
VO
Quality Assurance Specialist - Manufacturing (Rockville, MD)
Vicar Operating, Inc. dba VCA
United States
- $63,000 to $79,000 USD / year
The Quality Assurance Specialist supports daily Quality Assurance and compliance operations across manufacturing, distribution, and biobank facilities. Working under general supervision…
Added 7 mins ago
Manager, Quality Systems
Otsuka America Pharmaceutical Inc.
Jefferson City, MO
The Manager, Quality Systems is responsible for supporting the implementation, maintenance, optimization, and continuous improvement of global quality systems that enable compliance,…
Added 8 mins ago
Procurement Manager
Solar Energy Solutions
Lexington, KY
Solar Energy Solutions (SES) is seeking a Procurement Manager to lead purchasing, supplier management, inventory coordination, and material planning for residential, commercial, and small…
Added 8 mins ago
Internal IT Audit Manager
Cavco Industries, Inc.
Phoenix, AZ
At Cavco Industries, Inc. (NASDAQ CVCO), our 7000 team members are at the heart of everything we do. We design and produce quality, affordable factory-built homes. We are also a leading…
Added 8 mins ago
Program Manager - Education and Workforce Development (EWD) - FutureTex
North Carolina State University
Raleigh, NC
Operating within the Wilson College of Textiles at NC State University, the EWD Program Design & Implementation Manager manages the day-to-day design, development and operational execution…
Added 8 mins ago
Area Quality Assurance Manager
DHL
Waddell, AZ
Oversee the maintenance and continuous improvement of the overall quality system for multiple sites or multiple customers within a site, including management review, CAPA management,…
Added 8 mins ago
Manager Finance - Sales Incentive Planning and Analysis
Highmark Health
Jefferson City, MO
…position partners with senior executives on incentive strategy and design and leads a team responsible for accurate and timely incentive calculations, financial and performance analysis,…
Added 9 mins ago
Applied Artificial Intelligence Manager
ClimateWorks Foundation
Remote, United States
Design, build, and deploy AI-assisted workflows and LLM-powered tooling, including natural-language interfaces over the funding dataset, automated synthesis of recurring analyses, and…
Added 10 mins ago
Sr Mgr, Supplier Quality Management
x Varian Medical Systems, Inc.
United States
Varian Medical Systems, a Siemens Healthineers company, is seeking a Senior Manager, Supplier Quality Management to lead our Supplier Quality Management organization across the Americas. In…
Added 10 mins ago
CNC Operator I
Pelco Products Inc
Post Falls, ID
Produce machined parts by programming, setting up, and operating a computer numerical control (CNC) machine; maintaining quality and safety standards, maintaining equipment and supplies
Added 10 mins ago
Senior Director, Executive Recruitment
MSI - (Marvell Semiconductor Inc.) US
Santa Clara, CA · Chandler, AZ · Irvine, CA
Establish metrics and reporting (time to fill, quality of hire, candidate slates, costs, hiring manager and candidate satisfaction) to demonstrate the function’s impact.
Added 10 mins ago
Technical Lead - Simulation Assisted Engineering
GE Vernova Hitachi Nuclear Energy Americas LLC
United States
…physics, mathematics, and software-based modeling tools for design, analysis, or training involving; nuclear reactor thermal hydraulics, plant process fluidic and mechanical, electrical,…
Added 10 mins ago
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Senior Hardware Engineering Manager
Actalent
Pewaukee, WI
- $130,000 to $205,000 USD / year
Product Development ManagerJob DescriptionThe experienced Product Development Manager leads all product development activities, including an established systems engineering group, with a…

CURIA

Principal Engineer

United States

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Job details

Experience: Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Posting language: English
Posted: Nov 4, 2026

Original job description

Principal Engineer – Filling & Lyophilization – United States Build your future at Curia, where our work has the power to save lives. The Principal Engineer will lead equipment engineering for large capital projects in sterile filling and lyophilization to support Curia’s strategic growth. This includes leading network-wide capital execution to expand, modernize, and standardize manufacturing infrastructure. The incumbent will direct the specification, procurement, installation, commissioning, and qualification of advanced aseptic technologies to increase capacity, efficiency, and compliance for drug product programs. This position interfaces with Curia’s network manufacturing sites, client technical teams, and global leadership. The role provides technical oversight, mentorship, and engineering guidance across site-based teams and major capital project teams. Curia is a global contract development and manufacturing organization (CDMO) with over 30 years of experience partnering with pharmaceutical and biotech companies to provide life-saving treatments to patients. At Curia, we are on a mission to advance our customers’ therapies from curiosity to cure and ultimately to improve patients’ lives. We proudly offer

Generous benefit options (eligible first day of employment)
Paid training, vacation and holidays (vacation accrual begins on first day of employment)
Career advancement opportunities
Education reimbursement
401K program with matching contributions
Learning platform
And more!

Responsibilities

Capital Project Execution: Lead filling and lyophilization equipment engineering for major capital projects ($10M–$50M+) from conceptual design through Commissioning, Qualification, and Validation (CQV)
Technical Transfer & Client Support: Drive robust, on-time technical transfers of API and Drug Product (DP) programs, partnering with the Global Program Management Office and site technical operation teams to satisfy client expectations
Equipment Specification & Procurement: Author User Requirement Specifications (URS), drive vendor selection, conduct capital cost estimation, and lead Factory/Site Acceptance Testing (FAT/SAT) for primary equipment (fill lines, isolators, lyos, VHP, capping)
Network Capability & Talent Development: Mentor site-based engineering teams across the Curia network, sharing best practices, upgrading skill sets, and driving technical standardization
Operational Excellence & Continuous Improvement: Partner with sites to troubleshoot complex equipment deviations, increase OEE, reduce cycle times, and execute cost-improvement programs
Vendor & Engineering Firm Management: Oversee external engineering design firms, equipment vendors, and field contractors for filling and lyophilization installations
Regulatory Compliance: Ensure all equipment and system designs comply with cGMP, EU Annex 1 (Contamination Control Strategy), FDA guidance, and global regulatory standards
This job has no direct supervisory responsibilities; serves as a technical lead and matrix manager for project teams and site engineering resources
Travel Requirement: Up to 40% travel, including international travel to plant sites and vendor facilities Education and Experience
Education: BS in Mechanical, Chemical, Electrical, or Biomedical Engineering (or related discipline)
Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Capital Projects: Proven track record leading major capital equipment execution projects exceeding $10M Technical Expertise: Advanced expertise in
Aseptic processing, high-speed sterile filling (vials, syringes, cartridges), and barrier technology (Isolators/RABS)
Lyophilization processes and automated loading/unloading systems (ALUS)
Decontamination systems (VHP / Hydrogen Peroxide Vapor)
Sterilization processes (SIP, Autoclaves, Depyrogenation Tunnels)
Critical Utilities (WFI, Clean Steam, Clean Compressed Air, Process Gases, Cleanrooms, and HVAC)
Commissioning, Qualification, and Validation (CQV / ISPE Baseline Guide approach)
Regulatory & Quality Knowledge: Deep understanding of global pharmaceutical regulations (FDA cGMP, EMA, EU Annex 1, PIC/S) Skills & Capabilities
Analytical & Problem Solving: Demonstrated root-cause analysis skills (e.g., FMEA, 6-Sigma) to address complex process and equipment deviations
Communication & Stakeholder Management: Excellent verbal and written communication skills with experience presenting technical concepts to executive leadership, site teams, and external clients
Computer & Software Skills: Proficient in project management software, CAD systems, CMMS, Trackwise/QMS systems, MS Office Suite (Word, Excel, PowerPoint), and process automation systems (PLC/SCADA/DCS) Other Qualifications & Requirements
Must pass a background check and drug screen
Ability to work in cleanroom environments (Gowning required) Physical Demands & Work Environment
Physical Demands: Regularly required to talk, hear, sit, stand, walk, reach, and lift up to 25–50 lbs
Work Environment: Mix of office environment, active construction sites, and cGMP cleanrooms. Moderate noise level with exposure to moving mechanical parts and industrial chemical/utility systems This job description in no way states or implies that these are the only duties to be performed by the employee(s) incumbent in this position. Employees will be required to follow any other job-related instructions and to perform any other job-related duties requested by any person authorized to give instructions or assignments. All duties and responsibilities are essential functions and requirements and are subject to possible modification to reasonably accommodate individuals with disabilities. To perform this job successfully, the incumbents will possess the skills, aptitudes, and abilities to perform each duty proficiently. Some requirements may exclude individuals who pose a direct threat or significant risk to the health or safety of themselves or others. The requirements listed in this document are the minimum levels of knowledge, skills, or abilities. This document does not create an employment contract, implied or otherwise, other than an “at will” relationship.

Salary range:$120,200-$144,100/year Education, experience, location and tenure may be considered along with internal equity when job offers are extended. We do not accept unsolicited assistance from any headhunters or recruitment firms for any of our job openings. All resumes or profiles submitted by search firms to any employee at Curia, in any form without a valid, signed search agreement by an authorized signatory in place for the specific position, approved by Talent Acquisition, will be deemed the sole property of Curia. No fee will be paid in the event the candidate is hired by Curia because of the unsolicited referral.

All interested applicants must apply online. Please be aware of scammers. Curia will only send offer letters and requests for sensitive personal information from a curiaglobal.com email address. Curia is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Curia is an E-Verify employer.

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More about this job

Skills

Procurement
Regulatory compliance
Program management
Microsoft Office
Estimating
Process improvement
Troubleshoot
Biomedical engineering
Pharmaceutical technology
SIP
HVAC
Pharmaceutical legislation
Problem solving
Root cause analysis
Communication skills
Stakeholder management
Project management
CMMS
Microsoft Word
Microsoft Excel
Microsoft PowerPoint
PLC
SCADA
DCS
Heavy lifting

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