Jobs in the United States

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Added 7 mins ago
UA
INTERDISCIPLINARY (Technical Manager)
U.S. Army Corps of Engineers
New York, NY
- $105,481 to $137,128 USD / year
…for the technical and administrative management of Architect-Engineer (A-E) and/or in-house designs for the construction, maintenance, alteration, and repair…
Added 7 mins ago
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Senior Mechanical Engineer
GPAC
Altoona, IA
- $110,000 to $140,000 USD / year
We are seeking an experienced Senior Mechanical Engineer who can perform engineering related duties for the design and planning phases of multiple and/or large, complex design and…
Added 14 mins ago
Transportation Engineer
GPAC
Chicago, IL
Civil Roadway/Transportation Design Engineer with responsible for the planning, design, and development of transportation and roadway infrastructure projects from preliminary concepts…
Added 14 mins ago
Transportation Engineer
GPAC
Norcross, GA
Civil Roadway/Transportation Design Engineer with responsible for the planning, design, and development of transportation and roadway infrastructure projects from preliminary concepts…
Added 15 mins ago
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Civil Engineer - Land Development/Design
GPAC
Aurora, CO
- $115,000 to $145,000 USD / year
A well-established, reputable, and growing engineering and land planning firm, is looking for a Civil Engineer. We work hard to ensure that our projects are planned, designed & managed to…
Added 16 mins ago
Civil Project Engineer - Land Development
GPAC
New York, NY
We are seeking a motivated Civil Project Engineer to join our Land Development team. This individual will play a key role in designing site and infrastructure improvements, supporting…
Added 16 mins ago
Civil Project Manager - PE
GPAC
Atlanta, GA
We are seeking an experienced Professional Engineer (PE) to join our team in a Project Manager capacity. This individual will play a key role in leading civil projects, managing internal…
Added 16 mins ago
Structural Project Engineer
GPAC
Phoenix, AZ
We are seeking a Structural Project Engineer to join our Buildings team. This individual will play a key role in analyzing and designing structural systems for commercial, institutional,…
Added 17 mins ago
Senior AI/ML Engineer - LLM & Agent Stack (Customer Facing)
TrueFoundry
NY · San Mateo, CA
We are looking for a Senior AI/ML Engineer - LLM & Agent Stack (Customer-Facing) to join the team.
Added 24 mins ago
Staff Foundry Product Engineer
Samsung Austin Semiconductor, LLC.
Austin, TX
We are seeking a visionary engineer to architect sophisticated failure analysis workflows and develop advanced yield learning models that transform complex data into actionable…
Added 25 mins ago
Senior Software Engineer
Docusign
San Francisco, CA · Seattle, WA
As a Senior Software Engineer on the CLM - IAM Integrations team, you are responsible for building and maintaining key features that are integral to our customers and business. You are a…
Added 32 mins ago
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Electrical Design Engineer
GPAC
Charleston, SC
- $90,000 to $125,000 USD / year
Product Development: Design and develop electrical schematics, control systems, wiring harnesses, and printed circuit board (PCB) layouts.
Added 32 mins ago
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Electrical Design Engineer
GPAC
North Charleston, SC
- $90,000 to $125,000 USD / year
Product Development: Design and develop electrical schematics, control systems, wiring harnesses, and printed circuit board (PCB) layouts.
Added 32 mins ago
G
Civil/Site Land Development PE/PM
GPAC
Jacksonville, FL
- $100,000 to $140,000 USD / year
We are seeking an experienced Professional Engineer (PE) to join our Land Development team in a Project Manager capacity. This individual will play a key role in leading projects, managing…
Added 33 mins ago
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Electrical Design Engineer
GPAC
Mount Pleasant, SC
- $90,000 to $125,000 USD / year
Product Development: Design and develop electrical schematics, control systems, wiring harnesses, and printed circuit board (PCB) layouts.
Added 33 mins ago
G
Electrical Design Engineer
GPAC
Rock Hill, SC
- $90,000 to $125,000 USD / year
Product Development: Design and develop electrical schematics, control systems, wiring harnesses, and printed circuit board (PCB) layouts.
Added 33 mins ago
G
Electrical Design Engineer
GPAC
Greenville, SC
- $90,000 to $125,000 USD / year
Product Development: Design and develop electrical schematics, control systems, wiring harnesses, and printed circuit board (PCB) layouts.
Added 33 mins ago
G
Civil/Site Land Development PE/PM
GPAC
Miami, FL
- $100,000 to $140,000 USD / year
We are seeking an experienced Professional Engineer (PE) to join our Land Development team in a Project Manager capacity. This individual will play a key role in leading projects, managing…
Added 35 mins ago
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Controls Engineer
GPAC
Martinsville, IL
- $85,000 to $98,000 USD / year
Are you a hands-on Controls Engineer who enjoys solving real-world manufacturing challenges? This is an excellent opportunity to take ownership of PLC controls, industrial automation, plant…
Added 35 mins ago
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Controls Engineer
GPAC
Paris, IL
- $85,000 to $98,000 USD / year
Are you a hands-on Controls Engineer who enjoys solving real-world manufacturing challenges? This is an excellent opportunity to take ownership of PLC controls, industrial automation, plant…
Added 35 mins ago
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Controls Engineer
GPAC
West Terre Haute, IN
- $85,000 to $98,000 USD / year
Are you a hands-on Controls Engineer who enjoys solving real-world manufacturing challenges? This is an excellent opportunity to take ownership of PLC controls, industrial automation, plant…
Added 35 mins ago
G
Controls Engineer
GPAC
Fairbanks, IN
- $85,000 to $98,000 USD / year
Are you a hands-on Controls Engineer who enjoys solving real-world manufacturing challenges? This is an excellent opportunity to take ownership of PLC controls, industrial automation, plant…
Added 42 mins ago
Cloud Solution Engineer (Genomics & AI)
Oracle
Jefferson City, MO
The opportunity Oracle is seeking a senior pre-sales engineer with expertise in genomics, software engineering, and applied AI/ML. You will help molecular diagnostics companies, genomics…
Added 44 mins ago
Senior Software Engineer
Workato
San Francisco, CA
Workato is the leading Control and Execution Platform for Enterprise AI - the neutral platform enterprises trust to put AI to work across their business. Workato unifies data, applications,…
Added 44 mins ago
Guidance & Control Engineer (Associate or Experienced)
The Boeing Company
Saint Charles, MO
The Boeing Company is actively seeking an Associate or Experienced Guidance and Control (G&C) Engineer (Level 2 or 3) in St. Charles, Missouri to support our Weapons programs.

CURIA

Principal Engineer

United States

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Job details

Experience: Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Posting language: English
Posted: Nov 4, 2026

Original job description

Principal Engineer – Filling & Lyophilization – United States Build your future at Curia, where our work has the power to save lives. The Principal Engineer will lead equipment engineering for large capital projects in sterile filling and lyophilization to support Curia’s strategic growth. This includes leading network-wide capital execution to expand, modernize, and standardize manufacturing infrastructure. The incumbent will direct the specification, procurement, installation, commissioning, and qualification of advanced aseptic technologies to increase capacity, efficiency, and compliance for drug product programs. This position interfaces with Curia’s network manufacturing sites, client technical teams, and global leadership. The role provides technical oversight, mentorship, and engineering guidance across site-based teams and major capital project teams. Curia is a global contract development and manufacturing organization (CDMO) with over 30 years of experience partnering with pharmaceutical and biotech companies to provide life-saving treatments to patients. At Curia, we are on a mission to advance our customers’ therapies from curiosity to cure and ultimately to improve patients’ lives. We proudly offer

Generous benefit options (eligible first day of employment)
Paid training, vacation and holidays (vacation accrual begins on first day of employment)
Career advancement opportunities
Education reimbursement
401K program with matching contributions
Learning platform
And more!

Responsibilities

Capital Project Execution: Lead filling and lyophilization equipment engineering for major capital projects ($10M–$50M+) from conceptual design through Commissioning, Qualification, and Validation (CQV)
Technical Transfer & Client Support: Drive robust, on-time technical transfers of API and Drug Product (DP) programs, partnering with the Global Program Management Office and site technical operation teams to satisfy client expectations
Equipment Specification & Procurement: Author User Requirement Specifications (URS), drive vendor selection, conduct capital cost estimation, and lead Factory/Site Acceptance Testing (FAT/SAT) for primary equipment (fill lines, isolators, lyos, VHP, capping)
Network Capability & Talent Development: Mentor site-based engineering teams across the Curia network, sharing best practices, upgrading skill sets, and driving technical standardization
Operational Excellence & Continuous Improvement: Partner with sites to troubleshoot complex equipment deviations, increase OEE, reduce cycle times, and execute cost-improvement programs
Vendor & Engineering Firm Management: Oversee external engineering design firms, equipment vendors, and field contractors for filling and lyophilization installations
Regulatory Compliance: Ensure all equipment and system designs comply with cGMP, EU Annex 1 (Contamination Control Strategy), FDA guidance, and global regulatory standards
This job has no direct supervisory responsibilities; serves as a technical lead and matrix manager for project teams and site engineering resources
Travel Requirement: Up to 40% travel, including international travel to plant sites and vendor facilities Education and Experience
Education: BS in Mechanical, Chemical, Electrical, or Biomedical Engineering (or related discipline)
Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Capital Projects: Proven track record leading major capital equipment execution projects exceeding $10M Technical Expertise: Advanced expertise in
Aseptic processing, high-speed sterile filling (vials, syringes, cartridges), and barrier technology (Isolators/RABS)
Lyophilization processes and automated loading/unloading systems (ALUS)
Decontamination systems (VHP / Hydrogen Peroxide Vapor)
Sterilization processes (SIP, Autoclaves, Depyrogenation Tunnels)
Critical Utilities (WFI, Clean Steam, Clean Compressed Air, Process Gases, Cleanrooms, and HVAC)
Commissioning, Qualification, and Validation (CQV / ISPE Baseline Guide approach)
Regulatory & Quality Knowledge: Deep understanding of global pharmaceutical regulations (FDA cGMP, EMA, EU Annex 1, PIC/S) Skills & Capabilities
Analytical & Problem Solving: Demonstrated root-cause analysis skills (e.g., FMEA, 6-Sigma) to address complex process and equipment deviations
Communication & Stakeholder Management: Excellent verbal and written communication skills with experience presenting technical concepts to executive leadership, site teams, and external clients
Computer & Software Skills: Proficient in project management software, CAD systems, CMMS, Trackwise/QMS systems, MS Office Suite (Word, Excel, PowerPoint), and process automation systems (PLC/SCADA/DCS) Other Qualifications & Requirements
Must pass a background check and drug screen
Ability to work in cleanroom environments (Gowning required) Physical Demands & Work Environment
Physical Demands: Regularly required to talk, hear, sit, stand, walk, reach, and lift up to 25–50 lbs
Work Environment: Mix of office environment, active construction sites, and cGMP cleanrooms. Moderate noise level with exposure to moving mechanical parts and industrial chemical/utility systems This job description in no way states or implies that these are the only duties to be performed by the employee(s) incumbent in this position. Employees will be required to follow any other job-related instructions and to perform any other job-related duties requested by any person authorized to give instructions or assignments. All duties and responsibilities are essential functions and requirements and are subject to possible modification to reasonably accommodate individuals with disabilities. To perform this job successfully, the incumbents will possess the skills, aptitudes, and abilities to perform each duty proficiently. Some requirements may exclude individuals who pose a direct threat or significant risk to the health or safety of themselves or others. The requirements listed in this document are the minimum levels of knowledge, skills, or abilities. This document does not create an employment contract, implied or otherwise, other than an “at will” relationship.

Salary range:$120,200-$144,100/year Education, experience, location and tenure may be considered along with internal equity when job offers are extended. We do not accept unsolicited assistance from any headhunters or recruitment firms for any of our job openings. All resumes or profiles submitted by search firms to any employee at Curia, in any form without a valid, signed search agreement by an authorized signatory in place for the specific position, approved by Talent Acquisition, will be deemed the sole property of Curia. No fee will be paid in the event the candidate is hired by Curia because of the unsolicited referral.

All interested applicants must apply online. Please be aware of scammers. Curia will only send offer letters and requests for sensitive personal information from a curiaglobal.com email address. Curia is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Curia is an E-Verify employer.

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More about this job

Skills

Procurement
Regulatory compliance
Program management
Microsoft Office
Estimating
Process improvement
Troubleshoot
Biomedical engineering
Pharmaceutical technology
SIP
HVAC
Pharmaceutical legislation
Problem solving
Root cause analysis
Communication skills
Stakeholder management
Project management
CMMS
Microsoft Word
Microsoft Excel
Microsoft PowerPoint
PLC
SCADA
DCS
Heavy lifting

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