Jobs in the United States

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Added 1 min ago
Engineering Operations Technician
Amazon Data Services, Inc.
Manassas, VA
…troubleshooting, reporting to a site’s Data Center Facility Manager (FM). They will maintain, operate, and troubleshoot mission-critical data center facility equipment including stand-by…
Added 1 min ago
Finance Manager, Grocery Fulfillment
Amazon.com Services LLC
Nashville, TN · Bellevue, WA · Arlington, VA · New York, NY · Irving, TX
…initiatives such as grocery expansion, network growth, and new program evaluation across the fulfillment ecosystem. You will partner across multiple teams: Grocery FCs, Grocery DCs, Tech,…
Added 1 min ago
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Beverage Industry - Maintenance Technician, 2nd shift
Sunny Sky
Houston, TX
- $34 USD / hour
…plant operators, or through the direction of the Maintenance Manager and/or Plant…
Added 5 mins ago
Command and Control Network (C2NET) System Administrator SE-3
Odyssey Systems Consulting Group, Ltd.
Niceville, FL
Experience using scripting and automation technologies including Bash, PowerShell, and Python
Added 7 mins ago
Quantum Device Characterization Manager
Diraq
United States
The Quantum Device Characterization Manager leads a team responsible for the scalable characterization of silicon‑based quantum devices. This is a people leadership role requiring deep…
Added 9 mins ago
Manager, Orchestration & Integration Product Management
Visa U.S.A. Inc.
Foster City, CA · Austin, TX
Visa requires at least 3 days in office, expectations of these days will be confirmed by your Hiring Manager.
Added 9 mins ago
Production Planning Scheduling & Control Manager
Electrolux Consumer Products, Inc
United States
The Production Planning/Scheduling & Control (PPC) Manager leads end-to-end production planning, scheduling, and execution for a high-volume manufacturing facility. This role ensures…
Added 9 mins ago
Senior Analyst, Marketing Technology
HOME DEPOT MANAGEMENT COMPANY, LLC
United States
20% Optimizes Processes - Use data and insights to optimize processes and support through areas such as automation, incremental enhancements to system configurations, process improvement…
Added 9 mins ago
Senior Systems Engineer - Wireless & Wired Networking (Remote)
HOME DEPOT MANAGEMENT COMPANY, LLC
Remote, United States
This position typically reports to Systems Engineer Manager or Sr Manager
Added 12 mins ago
Software Engineer III
Yum!
Irvine, CA
…engineers. The SOFTWARE ENGINEER III will report to the Sr. Manager, Software Engineering as an individual…
Added 13 mins ago
Engineering Manager
Jabil Inc.
Prince George, VA
…a world-class manufacturing operation. The Site Engineering Manager will lead the development of manufacturing systems, production processes, facility layout, equipment deployment,…
Added 14 mins ago
HK
Customer Experience & Automation Manager
HEALTHY KIDS PROGRAMS
Carmel, NY
- $24 to $26 USD / hour
Healthy Kids Programs is seeking a Customer Experience & Automation Manager to support families through the enrollment process while helping us improve and streamline the systems behind it.
Added 15 mins ago
PMO Operations Manager
Dandy
Carrollton, TX
We're scaling fast, and we need an Operations Manager who thrives in complexity and moves with urgency. In this role, you'll be at the heart of our operations engine, driving the strategy…
Added 15 mins ago
PMO Operations Manager (UT)
Dandy
Lehi, UT
We're scaling fast, and we need an Operations Manager who thrives in complexity and moves with urgency. In this role, you'll be at the heart of our operations engine, driving the strategy…
Added 15 mins ago
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Control Technician
System One
Lyndhurst, NJ
- $37 to $42 USD / hour
Manage the Calibration Program, including: Calibration scheduling
Added 15 mins ago
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Test Engineering Intern
Skyworks
Richardson
- $23 to $49 USD / hour
…internal position you will be required to notify your current manager. Please refer to the Employee Transfers Guidelines posted on…
Added 15 mins ago
IT Operations Coordinator
TBA Credit Union
Traverse City, MI
…technology requests. Working under the direction of the IT Manager, the Coordinator manages recurring operational activities related to technology purchasing, asset tracking, vendor and…
Added 16 mins ago
Principal Technical Program Manager - 2290
Kioxia
Folsom, CA
KIOXIA America is seeking a Principal Technical Program Manager (TPM) to join the SSD Business Unit Program Management Office (PMO). This senior individual-contributor role will provide…
Added 17 mins ago
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Sr Manager, Performance Analytics & Insights, Oncology
Pfizer Inc
NY · IL · PA
- $124,400 to $207,400 USD / year
Senior Manager, Performance Analytics & Insights
Added 19 mins ago
SAP Portal Administrator- Clearance Required
Enterprise Horizon Consulting Group
Remote, United States
Hands-on administration and support of Control-M (including Enterprise Manager support: job scheduling, monitoring, troubleshooting)
Added 21 mins ago
Greenfield Manager, Startups
Vercel
NY · San Francisco, CA
…to build a foundation for adoption and expansion. By using automation and AI to maximize your team's impact, you'll turn wins into repeatable playbooks across the startup…
Added 24 mins ago
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Senior Systems Administrator
DREAM
NY
- $105,000 to $115,000 USD / year
Reporting to the Infrastructure Manager, the Senior Systems Administrator ensures that DREAM’s technology infrastructure is secure, reliable, and ready to scale across four campuses of a…
Added 26 mins ago
Training Manager 2
U.S. Bank National Association
Minneapolis, MN
…training administrative process and identifies opportunities for automation to improve efficiencies. Plans, develops, establishes and controls assigned organization and budget functions, as…
Added 26 mins ago
Operations Manager 4
U.S. Bank National Association
Saint Paul, MN
This Operations Manager will lead the Onboarding and Maintenance teams within Global Corporate Trust Paying & Transfer Agent Operations. The team supports new account and security setup,…
Added 26 mins ago
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(USA) Senior Director, Emerging Sales - Walmart Connect (SMB Advertiser Growth)
Walmart Inc.
AR
- $130,000 to $312,000 USD / year
Leadership includes two Directors, four senior managers, along with one Senior Manager.

CURIA

Principal Engineer

United States

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Job details

Experience: Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Posting language: English
Posted: Nov 4, 2026

Original job description

Principal Engineer – Filling & Lyophilization – United States Build your future at Curia, where our work has the power to save lives. The Principal Engineer will lead equipment engineering for large capital projects in sterile filling and lyophilization to support Curia’s strategic growth. This includes leading network-wide capital execution to expand, modernize, and standardize manufacturing infrastructure. The incumbent will direct the specification, procurement, installation, commissioning, and qualification of advanced aseptic technologies to increase capacity, efficiency, and compliance for drug product programs. This position interfaces with Curia’s network manufacturing sites, client technical teams, and global leadership. The role provides technical oversight, mentorship, and engineering guidance across site-based teams and major capital project teams. Curia is a global contract development and manufacturing organization (CDMO) with over 30 years of experience partnering with pharmaceutical and biotech companies to provide life-saving treatments to patients. At Curia, we are on a mission to advance our customers’ therapies from curiosity to cure and ultimately to improve patients’ lives. We proudly offer

Generous benefit options (eligible first day of employment)
Paid training, vacation and holidays (vacation accrual begins on first day of employment)
Career advancement opportunities
Education reimbursement
401K program with matching contributions
Learning platform
And more!

Responsibilities

Capital Project Execution: Lead filling and lyophilization equipment engineering for major capital projects ($10M–$50M+) from conceptual design through Commissioning, Qualification, and Validation (CQV)
Technical Transfer & Client Support: Drive robust, on-time technical transfers of API and Drug Product (DP) programs, partnering with the Global Program Management Office and site technical operation teams to satisfy client expectations
Equipment Specification & Procurement: Author User Requirement Specifications (URS), drive vendor selection, conduct capital cost estimation, and lead Factory/Site Acceptance Testing (FAT/SAT) for primary equipment (fill lines, isolators, lyos, VHP, capping)
Network Capability & Talent Development: Mentor site-based engineering teams across the Curia network, sharing best practices, upgrading skill sets, and driving technical standardization
Operational Excellence & Continuous Improvement: Partner with sites to troubleshoot complex equipment deviations, increase OEE, reduce cycle times, and execute cost-improvement programs
Vendor & Engineering Firm Management: Oversee external engineering design firms, equipment vendors, and field contractors for filling and lyophilization installations
Regulatory Compliance: Ensure all equipment and system designs comply with cGMP, EU Annex 1 (Contamination Control Strategy), FDA guidance, and global regulatory standards
This job has no direct supervisory responsibilities; serves as a technical lead and matrix manager for project teams and site engineering resources
Travel Requirement: Up to 40% travel, including international travel to plant sites and vendor facilities Education and Experience
Education: BS in Mechanical, Chemical, Electrical, or Biomedical Engineering (or related discipline)
Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Capital Projects: Proven track record leading major capital equipment execution projects exceeding $10M Technical Expertise: Advanced expertise in
Aseptic processing, high-speed sterile filling (vials, syringes, cartridges), and barrier technology (Isolators/RABS)
Lyophilization processes and automated loading/unloading systems (ALUS)
Decontamination systems (VHP / Hydrogen Peroxide Vapor)
Sterilization processes (SIP, Autoclaves, Depyrogenation Tunnels)
Critical Utilities (WFI, Clean Steam, Clean Compressed Air, Process Gases, Cleanrooms, and HVAC)
Commissioning, Qualification, and Validation (CQV / ISPE Baseline Guide approach)
Regulatory & Quality Knowledge: Deep understanding of global pharmaceutical regulations (FDA cGMP, EMA, EU Annex 1, PIC/S) Skills & Capabilities
Analytical & Problem Solving: Demonstrated root-cause analysis skills (e.g., FMEA, 6-Sigma) to address complex process and equipment deviations
Communication & Stakeholder Management: Excellent verbal and written communication skills with experience presenting technical concepts to executive leadership, site teams, and external clients
Computer & Software Skills: Proficient in project management software, CAD systems, CMMS, Trackwise/QMS systems, MS Office Suite (Word, Excel, PowerPoint), and process automation systems (PLC/SCADA/DCS) Other Qualifications & Requirements
Must pass a background check and drug screen
Ability to work in cleanroom environments (Gowning required) Physical Demands & Work Environment
Physical Demands: Regularly required to talk, hear, sit, stand, walk, reach, and lift up to 25–50 lbs
Work Environment: Mix of office environment, active construction sites, and cGMP cleanrooms. Moderate noise level with exposure to moving mechanical parts and industrial chemical/utility systems This job description in no way states or implies that these are the only duties to be performed by the employee(s) incumbent in this position. Employees will be required to follow any other job-related instructions and to perform any other job-related duties requested by any person authorized to give instructions or assignments. All duties and responsibilities are essential functions and requirements and are subject to possible modification to reasonably accommodate individuals with disabilities. To perform this job successfully, the incumbents will possess the skills, aptitudes, and abilities to perform each duty proficiently. Some requirements may exclude individuals who pose a direct threat or significant risk to the health or safety of themselves or others. The requirements listed in this document are the minimum levels of knowledge, skills, or abilities. This document does not create an employment contract, implied or otherwise, other than an “at will” relationship.

Salary range:$120,200-$144,100/year Education, experience, location and tenure may be considered along with internal equity when job offers are extended. We do not accept unsolicited assistance from any headhunters or recruitment firms for any of our job openings. All resumes or profiles submitted by search firms to any employee at Curia, in any form without a valid, signed search agreement by an authorized signatory in place for the specific position, approved by Talent Acquisition, will be deemed the sole property of Curia. No fee will be paid in the event the candidate is hired by Curia because of the unsolicited referral.

All interested applicants must apply online. Please be aware of scammers. Curia will only send offer letters and requests for sensitive personal information from a curiaglobal.com email address. Curia is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Curia is an E-Verify employer.

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More about this job

Skills

Procurement
Regulatory compliance
Program management
Microsoft Office
Estimating
Process improvement
Troubleshoot
Biomedical engineering
Pharmaceutical technology
SIP
HVAC
Pharmaceutical legislation
Problem solving
Root cause analysis
Communication skills
Stakeholder management
Project management
CMMS
Microsoft Word
Microsoft Excel
Microsoft PowerPoint
PLC
SCADA
DCS
Heavy lifting

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