Jobs in the United States

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Added 5 mins ago
Engineering Manager, Verification and Validation (STATCOM)
GE Grid Solutions, LLC
United States
…FACTS STATCOM team in Saratoga Springs, NY. This role will lead the verification and validation function for advanced control systems used in high-power reactive compensation applications,…
Added 6 mins ago
Engineer Senior Principal III – RF
BAE Systems
Westminster, CO
Simulate circuit and system performance using analytical software such as AWR Microwave Office, VSS, Agilent ADS, SystemVue, and MATLAB.
Added 6 mins ago
Cloud Engineer (Senior)
BAE Systems
Herndon, VA
We are looking for experienced System Engineers to join our technology-based program supporting a key government customer. This program will deliver engineering services for network…
Added 9 mins ago
Chassis Buyer - Watertown, SD or Waukesha, WI
ES Utilities South Dakota-USA
United States
…end Supply chain process for Chasiss procurement management, lead technical discussion, negotiation, ensure supplies from vendors for one or more of the Terex Utilities product lines.…
Added 14 mins ago
Engineer II, Field Software
ASM
United States
…4,500 ASMers representing 70 nationalities, our people and our advanced semiconductor devices are playing a crucial role in trends such as 5G, cloud computing, AI, and autonomous driving.…
Added 17 mins ago
W
(USA) Software Engineer III, Information Security
Walmart
BENTONVILLE, AR
- $90,000 to $180,000 USD / year
The Software Engineer III, Information Security, provides advanced support for enterprise security services by troubleshooting, analyzing, and resolving complex issues. This role involves…
Added 28 mins ago
Manufacturing Electrical Engineer
SEDAA
Plano, TX
The Manufacturing Electrical Engineer II will support manufacturing operations through the development, maintenance, troubleshooting, and continuous improvement of electrical test systems,…
Added 31 mins ago
Advanced Manufacturing Engineer, iPad
Apple
Cupertino, CA
…drive all technical operational issues related to yield and system integration processes to an effective closure to enable operational success of the entire new product introduction cycle…
Added 33 mins ago
A
Project Engineer
Actalent
Eden Prairie, MN
- $75,000 to $106,000 USD / year
5+ years of experience as a Mechanical Engineer serving as a technical lead on projects with a strong desire to transition into project management, OR at least 3+ years of direct project…
Added 39 mins ago
Sr Service Engineer, Avionics Service and Support (Onsite)
RTX
United States
Collins Aerospace seeks an experienced Senior Systems Engineer to join its service engineering and support team in Cedar Rapids, Iowa, with the ability to provide on-site support as needed…
Added 39 mins ago
Senior Software Engineer - Modeling (Onsite)
RTX
United States
Lead system design and integration efforts, ensuring seamless functionality across hardware and software components.
Added 39 mins ago
Senior Software Engineer - AVI MIL FMS (Onsite)
RTX
United States
Collins Aerospace is a leader in technologically advanced, intelligent solutions that help redefine the aerospace and defense industry. With a comprehensive portfolio and deep technical…
Added 39 mins ago
Software Engineer II - AVI MIL FMS (Onsite)
RTX
United States
Collins Aerospace is a leader in technologically advanced, intelligent solutions that help redefine the aerospace and defense industry. With a comprehensive portfolio and deep technical…
Added 41 mins ago
Senior Software Engineer - Agile Product Owner (Onsite)
RTX
United States
Senior Software Engineer - Agile Product Owner - Flight & Mission Simulation (Onsite)
Added 41 mins ago
Software Quality Engineer onsite Woburn, MA
RTX
United States
Leadership & teamwork – you will need to lead and organize resources for software quality activities on your assigned portfolio of programs and serve as the Subject Matter Expert (SME) for…
Added 41 mins ago
Manager Electro-Optical Integration and Test Section Lead
RTX
United States
…Responsibilities will be split between supporting EO program(s) as an engineer (~85%) and providing functional support to the section “EO Integration and Test Section”…
Added 41 mins ago
Lab Lead
RTX
United States
…development lifecycles for tests including test requirements, test system design, flight simulations, hardware-in-the-loop, computer-in-the-loop, advanced engineering prototyping…
Added 41 mins ago
Senior Manager Electro-Optical Integration and Test Section Lead
RTX
United States
…Responsibilities will be split between supporting EO program(s) as an engineer (~85%) and providing functional support to the section “EO Integration and Test Section”…
Added 43 mins ago
Software Engineer Senior
GD Information Technology, Inc.
United States
At GDIT, people are our differentiators. As a Software Engineer Senior you will apply sound technical judgment, collaborate across multidisciplinary teams, and deliver secure, maintainable…
Added 44 mins ago
Cross Domain Network Engineer, Lead
Booz Allen Hamilton_United States
Washington, DC · McLean, VA · Reston, VA
Cross Domain Network Engineer, LeadThe Opportunity:
Added 45 mins ago
Principal Software Development Engineer (AI Innovation)
CVS Health
Richardson, TX
The Principal Software Development Engineer will drive innovative, enterprise-wide solution designs at the business unit level for highly complex, strategic initiatives. In this high-impact…
Added 45 mins ago
Senior Software Engineer
US: Mastercard Technologies, LLC
O'Fallon, MO
Apply advanced data structures, algorithms, and software engineering principles to solve complex technical challenges and optimize system performance and resource utilization.
Added 50 mins ago
Lead Instrumentation & Controls Engineer 1 - Nuclear
Sargent & Lundy
Elkridge, MD
Develop and market high level, complex programs for nuclear power projects associated with design, operational excellence, safety, maintenance, and project management.
Added 1 hour ago
Piping Field Engineer - Testing
Bechtel
New Albany, OH
…program for piping, tubing, and components. Reporting to the Lead Pipe Testing Field Engineer, you will independently plan, prepare, execute, and document hydrostatic, pneumatic, and…
Added 1 hour ago
Senior Specialist, Mechanical Engineer (Mechanisms)
L3Harris Technologies
Chantilly, VA
Job Title: Sr. Specialist, Mechanical Engineer (Mechanisms)

CURIA

Principal Engineer

United States

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Job details

Experience: Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Posting language: English
Posted: Nov 4, 2026

Original job description

Principal Engineer – Filling & Lyophilization – United States Build your future at Curia, where our work has the power to save lives. The Principal Engineer will lead equipment engineering for large capital projects in sterile filling and lyophilization to support Curia’s strategic growth. This includes leading network-wide capital execution to expand, modernize, and standardize manufacturing infrastructure. The incumbent will direct the specification, procurement, installation, commissioning, and qualification of advanced aseptic technologies to increase capacity, efficiency, and compliance for drug product programs. This position interfaces with Curia’s network manufacturing sites, client technical teams, and global leadership. The role provides technical oversight, mentorship, and engineering guidance across site-based teams and major capital project teams. Curia is a global contract development and manufacturing organization (CDMO) with over 30 years of experience partnering with pharmaceutical and biotech companies to provide life-saving treatments to patients. At Curia, we are on a mission to advance our customers’ therapies from curiosity to cure and ultimately to improve patients’ lives. We proudly offer

Generous benefit options (eligible first day of employment)
Paid training, vacation and holidays (vacation accrual begins on first day of employment)
Career advancement opportunities
Education reimbursement
401K program with matching contributions
Learning platform
And more!

Responsibilities

Capital Project Execution: Lead filling and lyophilization equipment engineering for major capital projects ($10M–$50M+) from conceptual design through Commissioning, Qualification, and Validation (CQV)
Technical Transfer & Client Support: Drive robust, on-time technical transfers of API and Drug Product (DP) programs, partnering with the Global Program Management Office and site technical operation teams to satisfy client expectations
Equipment Specification & Procurement: Author User Requirement Specifications (URS), drive vendor selection, conduct capital cost estimation, and lead Factory/Site Acceptance Testing (FAT/SAT) for primary equipment (fill lines, isolators, lyos, VHP, capping)
Network Capability & Talent Development: Mentor site-based engineering teams across the Curia network, sharing best practices, upgrading skill sets, and driving technical standardization
Operational Excellence & Continuous Improvement: Partner with sites to troubleshoot complex equipment deviations, increase OEE, reduce cycle times, and execute cost-improvement programs
Vendor & Engineering Firm Management: Oversee external engineering design firms, equipment vendors, and field contractors for filling and lyophilization installations
Regulatory Compliance: Ensure all equipment and system designs comply with cGMP, EU Annex 1 (Contamination Control Strategy), FDA guidance, and global regulatory standards
This job has no direct supervisory responsibilities; serves as a technical lead and matrix manager for project teams and site engineering resources
Travel Requirement: Up to 40% travel, including international travel to plant sites and vendor facilities Education and Experience
Education: BS in Mechanical, Chemical, Electrical, or Biomedical Engineering (or related discipline)
Experience: Minimum 10+ years of pharmaceutical engineering experience in sterile drug product manufacturing or CDMO technical operations
Capital Projects: Proven track record leading major capital equipment execution projects exceeding $10M Technical Expertise: Advanced expertise in
Aseptic processing, high-speed sterile filling (vials, syringes, cartridges), and barrier technology (Isolators/RABS)
Lyophilization processes and automated loading/unloading systems (ALUS)
Decontamination systems (VHP / Hydrogen Peroxide Vapor)
Sterilization processes (SIP, Autoclaves, Depyrogenation Tunnels)
Critical Utilities (WFI, Clean Steam, Clean Compressed Air, Process Gases, Cleanrooms, and HVAC)
Commissioning, Qualification, and Validation (CQV / ISPE Baseline Guide approach)
Regulatory & Quality Knowledge: Deep understanding of global pharmaceutical regulations (FDA cGMP, EMA, EU Annex 1, PIC/S) Skills & Capabilities
Analytical & Problem Solving: Demonstrated root-cause analysis skills (e.g., FMEA, 6-Sigma) to address complex process and equipment deviations
Communication & Stakeholder Management: Excellent verbal and written communication skills with experience presenting technical concepts to executive leadership, site teams, and external clients
Computer & Software Skills: Proficient in project management software, CAD systems, CMMS, Trackwise/QMS systems, MS Office Suite (Word, Excel, PowerPoint), and process automation systems (PLC/SCADA/DCS) Other Qualifications & Requirements
Must pass a background check and drug screen
Ability to work in cleanroom environments (Gowning required) Physical Demands & Work Environment
Physical Demands: Regularly required to talk, hear, sit, stand, walk, reach, and lift up to 25–50 lbs
Work Environment: Mix of office environment, active construction sites, and cGMP cleanrooms. Moderate noise level with exposure to moving mechanical parts and industrial chemical/utility systems This job description in no way states or implies that these are the only duties to be performed by the employee(s) incumbent in this position. Employees will be required to follow any other job-related instructions and to perform any other job-related duties requested by any person authorized to give instructions or assignments. All duties and responsibilities are essential functions and requirements and are subject to possible modification to reasonably accommodate individuals with disabilities. To perform this job successfully, the incumbents will possess the skills, aptitudes, and abilities to perform each duty proficiently. Some requirements may exclude individuals who pose a direct threat or significant risk to the health or safety of themselves or others. The requirements listed in this document are the minimum levels of knowledge, skills, or abilities. This document does not create an employment contract, implied or otherwise, other than an “at will” relationship.

Salary range:$120,200-$144,100/year Education, experience, location and tenure may be considered along with internal equity when job offers are extended. We do not accept unsolicited assistance from any headhunters or recruitment firms for any of our job openings. All resumes or profiles submitted by search firms to any employee at Curia, in any form without a valid, signed search agreement by an authorized signatory in place for the specific position, approved by Talent Acquisition, will be deemed the sole property of Curia. No fee will be paid in the event the candidate is hired by Curia because of the unsolicited referral.

All interested applicants must apply online. Please be aware of scammers. Curia will only send offer letters and requests for sensitive personal information from a curiaglobal.com email address. Curia is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Curia is an E-Verify employer.

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More about this job

Skills

Procurement
Regulatory compliance
Program management
Microsoft Office
Estimating
Process improvement
Troubleshoot
Biomedical engineering
Pharmaceutical technology
SIP
HVAC
Pharmaceutical legislation
Problem solving
Root cause analysis
Communication skills
Stakeholder management
Project management
CMMS
Microsoft Word
Microsoft Excel
Microsoft PowerPoint
PLC
SCADA
DCS
Heavy lifting

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