Jobs in the United States

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Added 32 mins ago
Senior Automation Engineer
Clear Labs
San Carlos, CA
…variables systematically, and flagging labware-related findings to Systems Integration for formal…
Added 32 mins ago
Systems Integration Lead / Process Engineer
Clear Labs
San Carlos, CA
We're hiring a Systems Integration Lead to sit at the interface between assay science and automation engineering - taking benchtop assays and redesigning them into automation-friendly,…
Added 32 mins ago
DevOps Engineer
ClearlyAgile
Remote, United States
We are hiring an experienced DevOps Engineer to help us support existing and new customers. If you're dedicated, ambitious and have a passion for working with the latest leading edge Cloud…
Added 33 mins ago
VS
System Engineer
VT Services
Colorado Springs, CO
- $135,000 to $185,000 USD / year
VTG is looking for a System Engineer in Colorado Springs, CO. The Systems Engineer II performs systems engineering tasks with limited supervision, translating mission needs into system…
Added 35 mins ago
Software Test Engineer II
TGW Systems Inc
Grand Rapids, MI
The Software Test Engineer II is a mid-level engineer who supports a team of Software Engineers in the testing, commissioning, and ongoing support of TGW software solutions.
Added 58 mins ago
Engineer, Enterprise AI
NAVITUS HEALTH SOLUTIONS LLC
MIDDLETON, WI
Added 58 mins ago
Electrical Engineer
AMRON - DIV OF AMTEC CORP
ANTIGO, WI
Added 59 mins ago
Software Engineer II- ECM Specialization
EMERGENT HOLDINGS, INC.
NEW BERLIN, WI
Added 59 mins ago
Senior Software Engineer
J F AHERN
FOND DU LAC, WI
Added 59 mins ago
Electrical and Automation Design Enginee
BAXTER & WOODMAN INC
APPLETON, WI
Added 59 mins ago
Electrical engineer
BERNERS-SCHOBER ASSOCIATES INC
GREEN BAY, WI
Added 59 mins ago
Mechanical engineer
BERNERS-SCHOBER ASSOCIATES INC
GREEN BAY, WI
Added 1 hour ago
Project Engineer, Test
ROCKWELL AUTOMATION INC.
MILWAUKEE, WI
Added 1 hour ago
Training Environment Engineer - Military Health IT (JOMIS)
Rackner
Remote, United States
Training Environment Engineer - Military Health IT (JOMIS)
Added 1 hour ago
Data Systems AI / ML Engineer
Oak Ridge National Laboratory
Oak Ridge, TN
The Environmental Sciences Division (ESD) at Oak Ridge National Laboratory (ORNL) is seeking a Data Systems AI/ML Engineer for its Earth Sciences Informatics portfolio. In this role, you…
Added 1 hour ago
Sentinel - Systems Engineer (20086)
CORP-Corporate Office
United States
Northrop Grumman Defense Systems is seeking a Systems Engineer to join our team. This position will be located at Roy, UT to support the Sentinel (GBSD) program in the Strategic Deterrent…
Added 1 hour ago
Senior Forward Deployed Engineer
Raydar
Remote, United States
- Solid architecture skills: shaping complete systems, weighing integration options, drawing clear diagrams and explaining tradeoffs.
Added 1 hour ago
GD
CMSS Advanced Software Engineer (SATCOM and EW)
General Dynamics Mis
Colorado Springs, CO
- $118,519 to $131,482 USD / year
As a software engineer for CMSS , you'll be a member of a cross functional team responsible for analysis and resolution of security findings, design and implement complex system…
Added 1 hour ago
UO
Spacecraft Electrical Power Subsystem (EPS) Lead Engineer
University of Colorado Denver
Boulder, CO
- $145,754 to $229,394 USD / year
The applicant must be a hands-on engineer with strong electrical power system fundamentals and demonstrated experience taking spacecraft hardware through integration, test, and launch. The…
Added 1 hour ago
VS
Space Information System Security Engineer (ISSE)
VT Services
Aurora, CO
- $165,000 to $210,000 USD / year
…This IASAE experience requires working relevant types of Space systems based on location, and understanding space requirements and protection needs for integration into relevant network…
Added 1 hour ago
UO
Part-Time Electrical Engineer
University of Colorado Denver
Boulder, CO
- $34,986 USD / year
- Part-time
…Engineers work across mission classes and collaborate with systems, software, mechanical, thermal, science, quality, parts, radiation, manufacturing, and program-management…
Added 1 hour ago
VS
Information Assurance (IA) Lead
VT Services
Aurora, CO
- $195,000 to $220,000 USD / year
Relevant experience is required in: IA systems security engineering, engineering the concept, design, development, implementation, and or integration, from end-to-end (E2E), of a system or…
Added 1 hour ago
Software Engineer
Paragon Cyber Solutions
Crane, IN
Paragon Cyber Solutions has an immediate opening for those ready for an exciting and dynamic career as a Software Engineer to join other smart, talented, and dedicated engineers that pride…
Added 1 hour ago
Theater Engineer
Paragon Cyber Solutions
Colorado Springs, CO
The Theater Engineer is responsible for supporting the Shared Early Warning System (SEWS) global infrastructure and communications architecture across U.S. Combatant Commands and allied…
Added 1 hour ago
Lead Engineer I, System and Infrastructure Administrator (Re
KPMG LLP
SALT LAKE CITY, UT

Clear Labs

Systems Integration Lead / Process Engineer

San Carlos, CA, United States

Salary range: $160,808 to $196,544

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Job details

Pay: Salary range: $160,808 to $196,544
Posting language: English
Posted: Sep 17, 2026

Original job description

About Clear Labs Clear Labs builds an end-to-end, FDA-cleared next-generation sequencing (NGS) diagnostics platform. Our system, Clear Dx, combines automated sample-to-report workflows with an assay menu spanning oncology and infectious disease testing. We're a hands-on team building hardware, software, and wet-lab science together, and we're looking for senior engineers ready to take full ownership of systems, not just advise from the sidelines.

Position Summary We're hiring a Systems Integration Lead to sit at the interface between assay science and automation engineering - taking benchtop assays and redesigning them into automation-friendly, production-compatible processes. This is a hands-on, senior role responsible for labware qualification, system robustness and guardbanding, and designing and executing acceptance criteria and verification/validation as protocols move from bench to automated production, including closing the current gap where sequencing sits outside our automated oncology workflow as a manual, off-deck step.

Reports to: COO/CSO Location: San Carlos, CA Travel: No travel required.

Primary Responsibilities

Own labware selection, qualification, and system robustness/guardbanding across the automated platform, including DOE-driven robustness testing and failure-mode analysis for automated process steps.
Take benchtop assays developed by the assay science team and redesign them into automation-friendly, production-compatible processes.
Design and execute acceptance criteria and potentially verification/validation protocols as processes move from bench to automated production.
Drive on-deck integration of sequencing into oncology assay workflows, closing the current gap where sequencing runs as a manual, off-deck process outside the automated system.
Lead technical evaluation and integration of new NGS sequencing platforms (e.g., Illumina, Oxford Nanopore) and library prep chemistries onto the automated platform.
Serve as the technical bridge between assay science and automation engineering, translating wet-lab protocols into robust, industrialized, automatable processes.
Partner with Regulatory and Quality to ensure system and workflow changes are appropriately validated and documented for an FDA-cleared diagnostics environment.
Lead technical diligence on new sequencer, automation, and reagent vendor partnerships, including independently assessing vendor-provided integration timelines and effort estimates.
Senior level: 8+ years of hands-on process/automation engineering or systems integration experience in diagnostics, medical device, or another regulated laboratory environment for Senior level; 8–10+ years for Principal level - ideally including work translating early-stage or research-originated protocols into scaled automated production.
Working knowledge of FDA design-control and 510(k) considerations as they apply to system, workflow, and labware changes.
Prior experience in oncology diagnostics (companion diagnostics, comprehensive genomic profiling, or MRD workflows) strongly preferred.
Strong cross-functional communicator, comfortable translating between bench scientists and automation/hardware engineers.
A genuine preference for hands-on, at-the-bench work over slide review - you'll be building and testing systems yourself.

Technical Skills - NGS

Hands-on experience with at least one major NGS sequencing platform (Illumina and/or Oxford Nanopore), including run setup, sequencing chemistry, and flow cell/consumable workflows.
Working knowledge of NGS library preparation chemistries relevant to clinical panels (hybrid capture and/or amplicon-based enrichment).
Experience integrating or supporting a secondary analysis pipeline (e.g., DRAGEN or equivalent) and understanding how upstream lab changes propagate to sequencing QC metrics and analysis output.
Familiarity with NGS assay QC parameters and how automation or platform changes can affect them.

Technical Skills - Automation, Labware & Systems Robustness

Hands-on experience with Hamilton STAR/STAR2 liquid handling platforms, including VENUS software, deck design, and integrating third-party modules.
Demonstrated experience in labware selection, qualification, and DOE-based robustness testing (tolerance analysis, failure-mode analysis) for automated liquid-handling processes.
Strong statistical skills (design of experiments, process capability analysis, hypothesis testing, tolerance stack-up) applied to robustness and verification/validation study design.
Track record translating manual, research-originated wet-lab protocols into production-grade, automatable, robust processes suitable for a regulated environment.
Understanding of how liquid-handling method design and labware selection affect downstream NGS library quality and sequencing performance.
Salary range: $160,808 to $196,544
Medical, dental, and vision insurance
Employer-Sponsored Basic Life/AD&D, Long Term Disability
Employee Assistance Program (EAP)
Discretionary Time Off
Stock Option Plan
Lunch stipend for days at headquarters

Notice of E-Verify Participation: Clear Labs participates in the federal E-Verify program to confirm the identity and employment eligibility of all newly hired employees. For more information, please review the E-Verify Participation Poster (English/Spanish) and the Right to Work Poster (English/Spanish).

Disclaimer: The above job description is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of the Company.