Jobs in the United States

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Added 32 mins ago
Systems Integration Lead / Process Engineer
Clear Labs
San Carlos, CA
…hands-on, senior role responsible for labware qualification, system robustness and guardbanding, and designing and executing acceptance criteria and verification/validation as protocols…
Added 33 mins ago
VS
System Engineer
VT Services
Colorado Springs, CO
- $135,000 to $185,000 USD / year
VTG is looking for a System Engineer in Colorado Springs, CO. The Systems Engineer II performs systems engineering tasks with limited supervision, translating mission needs into system…
Added 46 mins ago
Electrical Controls Engineer IV
Lake Superior Consulting
Traverse City, MI · Houston, TX · Minneapolis, MN · Nashville, TN · Duluth, MN · Cranberry Township, PA · Omaha, NE
Lake Superior Consulting is seeking a Electrical Controls Engineer IV to join our team.
Added 51 mins ago
Cost Planning Principal Engineer
Honda Dev. and Mfg. of Am.,LLC
Raymond, OH
The Cost Planning Engineer has sufficient technical background to understand the cost drivers to be able to judge reasonableness of cost/investment in a given part or system.
Added 59 mins ago
Quality Engineer
KOCH INDUSTRIES INC
HUDSON, WI
Added 1 hour ago
Data Systems AI / ML Engineer
Oak Ridge National Laboratory
Oak Ridge, TN
The Environmental Sciences Division (ESD) at Oak Ridge National Laboratory (ORNL) is seeking a Data Systems AI/ML Engineer for its Earth Sciences Informatics portfolio. In this role, you…
Added 1 hour ago
Sentinel - Systems Engineer (20086)
CORP-Corporate Office
United States
Northrop Grumman Defense Systems is seeking a Systems Engineer to join our team. This position will be located at Roy, UT to support the Sentinel (GBSD) program in the Strategic Deterrent…
Added 1 hour ago
UO
Spacecraft Electrical Power Subsystem (EPS) Lead Engineer
University of Colorado Denver
Boulder, CO
- $145,754 to $229,394 USD / year
The EPS Lead is the responsible engineer for the spacecraft power subsystem and the electrical aspects of the solar-electric propulsion (SEP) system. This includes the li-ion battery, power…
Added 1 hour ago
Product Pathfinding Engineer- HIG-TPG
Micron Technology, Inc.
Boise, ID
Forge strong alliances with Build, Verification, Product Architecture, System Compatibility Group, and Silicon Strategy teams to deliver products in an effective and efficient manner.
Added 1 hour ago
Software Engineer
Paragon Cyber Solutions
Crane, IN
Support software testing activities including unit testing, software integration testing, system-level testing, regression analysis, and independent verification and validation (IV&V).
Added 1 hour ago
Senior RMF Engineer
Paragon Cyber Solutions
Aberdeen Proving Ground, MD
Paragon Cyber Solutions is seeking a Senior RMF Engineer to provide cybersecurity engineering and DoD Risk Management Framework (RMF) support to the U.S. Army Aberdeen Test Center (ATC).…
Added 2 hours ago
Senior Manufacturing And Automation Engineer
Amazon
Redmond, WA
Amazon LEO is seeking a Senior Manufacturing And Automation Engineer to develop, automate, and scale manufacturing processes for complex aerospace hardware, including PCBAs, battery packs,…
Added 3 hours ago
General/Interdisciplinary Engineer, Senior
HX5, LLC
US-UT-Ogden, UT
HX5 is currently seeking a qualified Senior General/Interdisciplinary Engineer to support the Aerospace Dominance Enabler Division (AFLCMC/C3BM) at Hill AFB in Ogden Utah. This role…
Added 3 hours ago
Data Engineering/Analytics Support
CACI International
Norco, CA
We are seeking a flexible, proactive, and detail-oriented engineer with a passion for analytics and a commitment to delivering high-quality products under government direction.
Added 3 hours ago
Data Engineering/Analytics Support
CACI International
Norco, CA
We are seeking a flexible, proactive, and detail-oriented engineer with a passion for analytics and a commitment to delivering high-quality products under government direction.
Added 3 hours ago
Data Engineering/Analytics Support
CACI International
Norco, CA
We are seeking a flexible, proactive, and detail-oriented engineer with a passion for analytics and a commitment to delivering high-quality products under government direction.
Added 3 hours ago
Network Development Engineer II , ALG Software and Network Integration and Test
Amazon
NORTHRIDGE, CA
We're looking for a Network Development Engineer who can design, build, and operate network infrastructure across data center and engineering environments. You'll own architectures that…
Added 3 hours ago
Engineer I, Manufacturing
Abbott
Pleasanton, CA
Assist in the design, development, verification, and validation of new manufacturing processes and equipment.
Added 3 hours ago
Principal Design Verification Engineer , Annapurna Labs
Amazon
Cupertino, CA
We are looking for a passionate Principal Design Verification Engineer to join our newly formed team responsible for verifying high-speed I/O and scale-up/out components across the SoC. You…
Added 3 hours ago
Principal or Sr Principal Engineer Electrical
Northrop Grumman
San Diego, CA
Northrop Grumman Aeronautics Systems MQ-4 Triton Program seeks a Principal or Sr. Principal Engineer Electrical to support the Vehicle Management Subsystem's Hardware Avionics team in…
Added 4 hours ago
CC
Quality Lead/ Quality Engineer
Custom Cylinders, Inc
Cary, IL
- $70,000 to $85,000 USD / year
As a Quality Engineer, you’ll help ensure that our pneumatic and hydraulic cylinders meet demanding performance and reliability standards. You’ll support our ISO 9001–certified quality…
Added 4 hours ago
Controls Engineer / Automation Engineer
Cache Valley Electric
Logan, UT
· Perform I/O checkout and system verification.
Added 4 hours ago
Associate, Electrical Engineering (Rochester, NY)
L3Harris
Rochester, NY
Perform system analysis to determine feasibility of design within time and cost constraints
Added 4 hours ago
Data Center Hardware Engineering - Hardware Technician
Apple
Austin, TX
…services and products at scale. From custom silicon to full-system integration, our work ensures that Apple's global infrastructure is fast, efficient, and built to last. The Hardware…
Added 5 hours ago
UO
Senior Guidance, Navigation, & Control Engineer
University of Colorado Denver
Boulder, CO
- $34,986 USD / year
LASP is seeking a full-time Guidance, Navigation & Controls (GNC) system engineer for an asteroid exploration mission.

Clear Labs

Systems Integration Lead / Process Engineer

San Carlos, CA, United States

Salary range: $160,808 to $196,544

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Job details

Pay: Salary range: $160,808 to $196,544
Posting language: English
Posted: Sep 17, 2026

Original job description

About Clear Labs Clear Labs builds an end-to-end, FDA-cleared next-generation sequencing (NGS) diagnostics platform. Our system, Clear Dx, combines automated sample-to-report workflows with an assay menu spanning oncology and infectious disease testing. We're a hands-on team building hardware, software, and wet-lab science together, and we're looking for senior engineers ready to take full ownership of systems, not just advise from the sidelines.

Position Summary We're hiring a Systems Integration Lead to sit at the interface between assay science and automation engineering - taking benchtop assays and redesigning them into automation-friendly, production-compatible processes. This is a hands-on, senior role responsible for labware qualification, system robustness and guardbanding, and designing and executing acceptance criteria and verification/validation as protocols move from bench to automated production, including closing the current gap where sequencing sits outside our automated oncology workflow as a manual, off-deck step.

Reports to: COO/CSO Location: San Carlos, CA Travel: No travel required.

Primary Responsibilities

Own labware selection, qualification, and system robustness/guardbanding across the automated platform, including DOE-driven robustness testing and failure-mode analysis for automated process steps.
Take benchtop assays developed by the assay science team and redesign them into automation-friendly, production-compatible processes.
Design and execute acceptance criteria and potentially verification/validation protocols as processes move from bench to automated production.
Drive on-deck integration of sequencing into oncology assay workflows, closing the current gap where sequencing runs as a manual, off-deck process outside the automated system.
Lead technical evaluation and integration of new NGS sequencing platforms (e.g., Illumina, Oxford Nanopore) and library prep chemistries onto the automated platform.
Serve as the technical bridge between assay science and automation engineering, translating wet-lab protocols into robust, industrialized, automatable processes.
Partner with Regulatory and Quality to ensure system and workflow changes are appropriately validated and documented for an FDA-cleared diagnostics environment.
Lead technical diligence on new sequencer, automation, and reagent vendor partnerships, including independently assessing vendor-provided integration timelines and effort estimates.
Senior level: 8+ years of hands-on process/automation engineering or systems integration experience in diagnostics, medical device, or another regulated laboratory environment for Senior level; 8–10+ years for Principal level - ideally including work translating early-stage or research-originated protocols into scaled automated production.
Working knowledge of FDA design-control and 510(k) considerations as they apply to system, workflow, and labware changes.
Prior experience in oncology diagnostics (companion diagnostics, comprehensive genomic profiling, or MRD workflows) strongly preferred.
Strong cross-functional communicator, comfortable translating between bench scientists and automation/hardware engineers.
A genuine preference for hands-on, at-the-bench work over slide review - you'll be building and testing systems yourself.

Technical Skills - NGS

Hands-on experience with at least one major NGS sequencing platform (Illumina and/or Oxford Nanopore), including run setup, sequencing chemistry, and flow cell/consumable workflows.
Working knowledge of NGS library preparation chemistries relevant to clinical panels (hybrid capture and/or amplicon-based enrichment).
Experience integrating or supporting a secondary analysis pipeline (e.g., DRAGEN or equivalent) and understanding how upstream lab changes propagate to sequencing QC metrics and analysis output.
Familiarity with NGS assay QC parameters and how automation or platform changes can affect them.

Technical Skills - Automation, Labware & Systems Robustness

Hands-on experience with Hamilton STAR/STAR2 liquid handling platforms, including VENUS software, deck design, and integrating third-party modules.
Demonstrated experience in labware selection, qualification, and DOE-based robustness testing (tolerance analysis, failure-mode analysis) for automated liquid-handling processes.
Strong statistical skills (design of experiments, process capability analysis, hypothesis testing, tolerance stack-up) applied to robustness and verification/validation study design.
Track record translating manual, research-originated wet-lab protocols into production-grade, automatable, robust processes suitable for a regulated environment.
Understanding of how liquid-handling method design and labware selection affect downstream NGS library quality and sequencing performance.
Salary range: $160,808 to $196,544
Medical, dental, and vision insurance
Employer-Sponsored Basic Life/AD&D, Long Term Disability
Employee Assistance Program (EAP)
Discretionary Time Off
Stock Option Plan
Lunch stipend for days at headquarters

Notice of E-Verify Participation: Clear Labs participates in the federal E-Verify program to confirm the identity and employment eligibility of all newly hired employees. For more information, please review the E-Verify Participation Poster (English/Spanish) and the Right to Work Poster (English/Spanish).

Disclaimer: The above job description is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of the Company.