Jobs in the United States

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Added 1 hour ago
SME Network Engineer
CACI International
Ashburn, VA
CACI is seeking a SME Network Engineer for the Global Mission Operations Support (GMOS) contract, supporting the Department of State. This role offers a unique opportunity to enhance…
Added 1 hour ago
Agile Coach and Release Train Engineer
BOOZ, ALLEN & HAMILTON, INC.
Reston, VA
Are you looking for an opportunity to combine your technical systems engineering skills with big picture execution and leadership to make a mission impact and support the warfighter? You…
Added 1 hour ago
Senior Automation Engineer
Clear Labs
San Carlos, CA
We're hiring a Senior Automation Engineer to strengthen the performance, reliability, and validation of the laboratory automation supporting our FDA-cleared NGS diagnostics platform. This…
Added 1 hour ago
Systems Integration Lead / Process Engineer
Clear Labs
San Carlos, CA
We're hiring a Systems Integration Lead to sit at the interface between assay science and automation engineering - taking benchtop assays and redesigning them into automation-friendly,…
Added 3 hours ago
Korean Bilingual Process Engineer
Cesna Recruitment
Tarboro, NC
Under the general supervision and guidance of the Engineering Manager or senior engineer to whom assigned, perform a variety of functions in the development and/or improvement of production…
Added 4 hours ago
Senior Manufacturing And Automation Engineer
Amazon
Redmond, WA
Amazon LEO is seeking a Senior Manufacturing And Automation Engineer to develop, automate, and scale manufacturing processes for complex aerospace hardware, including PCBAs, battery packs,…
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Data Engineering/Analytics Support
CACI International
Norco, CA
We are seeking a flexible, proactive, and detail-oriented engineer with a passion for analytics and a commitment to delivering high-quality products under government direction.
Added 4 hours ago
Data Engineering/Analytics Support
CACI International
Norco, CA
We are seeking a flexible, proactive, and detail-oriented engineer with a passion for analytics and a commitment to delivering high-quality products under government direction.
Added 4 hours ago
Data Engineering/Analytics Support
CACI International
Norco, CA
We are seeking a flexible, proactive, and detail-oriented engineer with a passion for analytics and a commitment to delivering high-quality products under government direction.
Added 5 hours ago
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Senior Full-Stack Engineer
True Talent Solutions Partners
Remote, United States
- $200,000 to $275,000 USD / year
Join a small engineering team building a marketplace for GPU compute. This senior, backend-focused role combines architecture, hands-on development, and product collaboration to deliver…
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Electrical and Automation Design Engineer
Harrison Consulting Solutions
Milwaukee, WI
Midwest multi-disciplined engineering firm is looking to add a Senior Electrical and
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Senior AI Engineer
TSGUS HCG LLC
Remote, United States
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Added 6 hours ago
Senior Java Platform Development Engineer Advanced NYC, NY
Innova Solutions Inc
NEW YORK, NY
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Electrical and Automation Design Engineer
Harrison Consulting Solutions
Houston, TX
Midwest multi-disciplined engineering firm is looking to add a Senior Electrical and
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Austin, TX
Midwest multi-disciplined engineering firm is looking to add a Senior Electrical and
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Cloud Adoption Engineer - Oracle Government, Defense & Intelligence
Oracle
Reston, VA · Washington, DC
You will own the quality and completion of assigned Cloud Adoption Engineering deliverables, working with the Senior Manager of Cloud Adoption Engineering and relevant technical specialists.
Added 7 hours ago
Quality Assurance Engineer
Braven
Remote, United States
In order to achieve its ambition of serving 80,000–100,000 Fellows over the next decade, Braven is hiring a Quality Assurance Engineer who will ensure our student- and staff-facing software…
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Principal Mixed Signal Design Engineer
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(USA) Senior, Software Engineer
Walmart
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- $117,000 to $234,000 USD / year
Own delivery of scoped features and models through collaborative engineering teams, ensuring alignment with platform and system objectives.
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Air Proprietary Senior Tooling Engineer
The Boeing Company
Berkeley, MO
Refer to The Boeing Defense, Space & Security (BDS) team is seeking a motivated Senior Tooling Engineer located in Berkeley, MO .
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Senior Mainframe z/OS Engineer (Remote/ Work from
First National Bank of Omaha
Byhalia, MS
Added 9 hours ago
UO
Senior FPGA Development Engineer
University of Colorado Denver
Boulder, CO
- $34,986 USD / year
The Laboratory for Atmospheric and Space Physics (LASP) is seeking an FPGA Design Engineer IV to serve as a senior technical leader for flight digital logic used in spaceflight science…
Added 9 hours ago
Senior AI Operations Engineer (Senior Software Engineer)
Vizient, Inc.
Centennial, CO
Added 9 hours ago
Senior AI Operations Engineer (Senior Software Engineer)
Vizient, Inc.
Centennial, CO
Added 10 hours ago
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Senior AI Engineer
Premier Global Links
San Francisco · San Francisco, CA
- $180,000 to $275,000 USD / year
Premier Global Links LLC is seeking an experienced Senior AI Engineer for an innovative financial technology company developing AI-powered business software, financial products, and…

Clear Labs

Systems Integration Lead / Process Engineer

San Carlos, CA, United States

Salary range: $160,808 to $196,544

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Job details

Pay: Salary range: $160,808 to $196,544
Posting language: English
Posted: Sep 17, 2026

Original job description

About Clear Labs Clear Labs builds an end-to-end, FDA-cleared next-generation sequencing (NGS) diagnostics platform. Our system, Clear Dx, combines automated sample-to-report workflows with an assay menu spanning oncology and infectious disease testing. We're a hands-on team building hardware, software, and wet-lab science together, and we're looking for senior engineers ready to take full ownership of systems, not just advise from the sidelines.

Position Summary We're hiring a Systems Integration Lead to sit at the interface between assay science and automation engineering - taking benchtop assays and redesigning them into automation-friendly, production-compatible processes. This is a hands-on, senior role responsible for labware qualification, system robustness and guardbanding, and designing and executing acceptance criteria and verification/validation as protocols move from bench to automated production, including closing the current gap where sequencing sits outside our automated oncology workflow as a manual, off-deck step.

Reports to: COO/CSO Location: San Carlos, CA Travel: No travel required.

Primary Responsibilities

Own labware selection, qualification, and system robustness/guardbanding across the automated platform, including DOE-driven robustness testing and failure-mode analysis for automated process steps.
Take benchtop assays developed by the assay science team and redesign them into automation-friendly, production-compatible processes.
Design and execute acceptance criteria and potentially verification/validation protocols as processes move from bench to automated production.
Drive on-deck integration of sequencing into oncology assay workflows, closing the current gap where sequencing runs as a manual, off-deck process outside the automated system.
Lead technical evaluation and integration of new NGS sequencing platforms (e.g., Illumina, Oxford Nanopore) and library prep chemistries onto the automated platform.
Serve as the technical bridge between assay science and automation engineering, translating wet-lab protocols into robust, industrialized, automatable processes.
Partner with Regulatory and Quality to ensure system and workflow changes are appropriately validated and documented for an FDA-cleared diagnostics environment.
Lead technical diligence on new sequencer, automation, and reagent vendor partnerships, including independently assessing vendor-provided integration timelines and effort estimates.
Senior level: 8+ years of hands-on process/automation engineering or systems integration experience in diagnostics, medical device, or another regulated laboratory environment for Senior level; 8–10+ years for Principal level - ideally including work translating early-stage or research-originated protocols into scaled automated production.
Working knowledge of FDA design-control and 510(k) considerations as they apply to system, workflow, and labware changes.
Prior experience in oncology diagnostics (companion diagnostics, comprehensive genomic profiling, or MRD workflows) strongly preferred.
Strong cross-functional communicator, comfortable translating between bench scientists and automation/hardware engineers.
A genuine preference for hands-on, at-the-bench work over slide review - you'll be building and testing systems yourself.

Technical Skills - NGS

Hands-on experience with at least one major NGS sequencing platform (Illumina and/or Oxford Nanopore), including run setup, sequencing chemistry, and flow cell/consumable workflows.
Working knowledge of NGS library preparation chemistries relevant to clinical panels (hybrid capture and/or amplicon-based enrichment).
Experience integrating or supporting a secondary analysis pipeline (e.g., DRAGEN or equivalent) and understanding how upstream lab changes propagate to sequencing QC metrics and analysis output.
Familiarity with NGS assay QC parameters and how automation or platform changes can affect them.

Technical Skills - Automation, Labware & Systems Robustness

Hands-on experience with Hamilton STAR/STAR2 liquid handling platforms, including VENUS software, deck design, and integrating third-party modules.
Demonstrated experience in labware selection, qualification, and DOE-based robustness testing (tolerance analysis, failure-mode analysis) for automated liquid-handling processes.
Strong statistical skills (design of experiments, process capability analysis, hypothesis testing, tolerance stack-up) applied to robustness and verification/validation study design.
Track record translating manual, research-originated wet-lab protocols into production-grade, automatable, robust processes suitable for a regulated environment.
Understanding of how liquid-handling method design and labware selection affect downstream NGS library quality and sequencing performance.
Salary range: $160,808 to $196,544
Medical, dental, and vision insurance
Employer-Sponsored Basic Life/AD&D, Long Term Disability
Employee Assistance Program (EAP)
Discretionary Time Off
Stock Option Plan
Lunch stipend for days at headquarters

Notice of E-Verify Participation: Clear Labs participates in the federal E-Verify program to confirm the identity and employment eligibility of all newly hired employees. For more information, please review the E-Verify Participation Poster (English/Spanish) and the Right to Work Poster (English/Spanish).

Disclaimer: The above job description is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of the Company.