Jobs in the United States

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Added 12 mins ago
Quality Engineer III (QA Systems)
Parker Hannifin Corporation
Lexington, KY
The Quality Engineer III is a senior site-level role responsible for assessing and supporting complex quality performance issues across multiple value streams and functional specialties.…
Added 43 mins ago
SME Network Engineer
CACI International
Ashburn, VA
CACI is seeking a SME Network Engineer for the Global Mission Operations Support (GMOS) contract, supporting the Department of State. This role offers a unique opportunity to enhance…
Added 43 mins ago
Senior Network Engineer (Firewall)
CACI International
Ashburn, VA
Job Title: Senior Network Engineer (Firewall)
Added 44 mins ago
Systems Engineer, Senior
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…management. You will trace requirements, acceptance criteria, performance requirements, and key performance parameters (KPPs). Additionally, you will identify gaps between requirements and…
Added 1 hour ago
Systems Integration Lead / Process Engineer
Clear Labs
San Carlos, CA
…software, and wet-lab science together, and we're looking for senior engineers ready to take full ownership of systems, not just advise from the…
Added 1 hour ago
A
Google Data Specialist
Accenture
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- $70,350 to $196,000 USD / year
…architecture design, build data pipelines and models, perform analysis, and contribute to technical implementations under guidance from senior team…
Added 1 hour ago
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Google Senior Data Engineer
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Oklahoma City, OK
- $94,400 to $266,300 USD / year
As a GCP Senior Data Engineer, you will help deliver data modernization, analytics, and AI solutions on GCP. You will support architecture design, build data pipelines and models, perform…
Added 2 hours ago
Mechanical engineer
BERNERS-SCHOBER ASSOCIATES INC
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Devops Engineer Senior
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Senior Cost Planning Engineer
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Senior Intermediate Planning Engineer
MISO Default Brand
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- $127,000 to $152,000 USD / year
As a Senior Engineer – Intermediate Planning, you’ll help MISO bridge the critical space between long-term transmission planning and real-time operations. Your work will focus on the…
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Automobile Quality & Development Engineer
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- $70,000 to $100,000 USD / year
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Added 3 hours ago
Senior Mechanical Engineer
Central Moloney
Remote, United States
The Mechanical Engineer will be responsible for the mechanical design and development of distribution transformers in compliance with IEEE, CSA, and customer specifications. This role…
Added 3 hours ago
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Principal Software Engineering - Reliability and FinOps Engineer
AT&T
Bothell, WA
- $155,400 to $261,100 USD / year
As a Principal System Engineer, you will serve as a senior technical leader across FinOps, cloud optimization, system reliability, and AI-driven automation. You will shape and execute…
Added 3 hours ago
Senior Manufacturing And Automation Engineer
Amazon
Redmond, WA
Amazon LEO is seeking a Senior Manufacturing And Automation Engineer to develop, automate, and scale manufacturing processes for complex aerospace hardware, including PCBAs, battery packs,…
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Senior Project Manager
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Wilmington, VA
This is a senior, customer-facing delivery role with responsibility for a portfolio of projects, senior stakeholder relationships, financial performance, and the leadership of Project…
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General/Interdisciplinary Engineer, Senior
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HX5 is currently seeking a qualified Senior General/Interdisciplinary Engineer to support the Aerospace Dominance Enabler Division (AFLCMC/C3BM) at Hill AFB in Ogden Utah. This role…
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Senior Supplier Industrialization Engineer, Composite Structures
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Remote, United States
The Senior Supplier Industrialization Engineer, Composite Structures is a high-profile, cross functional position that plays an integral role in enabling development and production flow of…
Added 4 hours ago
Data Engineering/Analytics Support
CACI International
Norco, CA
Data Analysis & Interpretation: Assist in analyzing data from Defense and Integrated Combat Systems training, testing, and evaluation events to identify trends in system performance.…
Added 4 hours ago
Data Engineering/Analytics Support
CACI International
Norco, CA
Data Analysis & Interpretation: Assist in analyzing data from Defense and Integrated Combat Systems training, testing, and evaluation events to identify trends in system performance.…
Added 4 hours ago
Data Engineering/Analytics Support
CACI International
Norco, CA
Data Analysis & Interpretation: Assist in analyzing data from Defense and Integrated Combat Systems training, testing, and evaluation events to identify trends in system performance.…
Added 4 hours ago
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Sr Controls Engineer
The Walt Disney Company
Anaheim, CA
- $130,800 to $159,800 USD / year
As a Sustaining Controls Engineer, you will have the opportunity to work on the Ride Control aspect of Registered Attractions for Walt Disney Parks & Resorts. You will be hands-on,…
Added 4 hours ago
Senior Director of Preservation - 3960025
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The Senior Director of Preservation will design and lead a scalable investment platform that integrates disciplined real estate execution with a mission-driven, faith-based, and…
Added 4 hours ago
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Senior Software Engineer
Odyssey Systems Cons
Colorado Springs, CO
- $31,533 USD / year
We are seeking a Senior Software Engineer to be a primary technical contributor on the Multimode Threat Engagement Simulation Platform. You will own significant portions of the stack…
Added 4 hours ago
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Systems Cybersecurity Engineer
Odyssey Systems Cons
Colorado Springs, CO
- $31,533 USD / year
Odyssey is recruiting for a senior System Cybersecurity Engineer to join our elite team at Peterson Space Force Base in Colorado Springs, Colorado. In this role, you will be a hands-on…

Clear Labs

Systems Integration Lead / Process Engineer

San Carlos, CA, United States

Salary range: $160,808 to $196,544

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Job details

Pay: Salary range: $160,808 to $196,544
Posting language: English
Posted: Sep 17, 2026

Original job description

About Clear Labs Clear Labs builds an end-to-end, FDA-cleared next-generation sequencing (NGS) diagnostics platform. Our system, Clear Dx, combines automated sample-to-report workflows with an assay menu spanning oncology and infectious disease testing. We're a hands-on team building hardware, software, and wet-lab science together, and we're looking for senior engineers ready to take full ownership of systems, not just advise from the sidelines.

Position Summary We're hiring a Systems Integration Lead to sit at the interface between assay science and automation engineering - taking benchtop assays and redesigning them into automation-friendly, production-compatible processes. This is a hands-on, senior role responsible for labware qualification, system robustness and guardbanding, and designing and executing acceptance criteria and verification/validation as protocols move from bench to automated production, including closing the current gap where sequencing sits outside our automated oncology workflow as a manual, off-deck step.

Reports to: COO/CSO Location: San Carlos, CA Travel: No travel required.

Primary Responsibilities

Own labware selection, qualification, and system robustness/guardbanding across the automated platform, including DOE-driven robustness testing and failure-mode analysis for automated process steps.
Take benchtop assays developed by the assay science team and redesign them into automation-friendly, production-compatible processes.
Design and execute acceptance criteria and potentially verification/validation protocols as processes move from bench to automated production.
Drive on-deck integration of sequencing into oncology assay workflows, closing the current gap where sequencing runs as a manual, off-deck process outside the automated system.
Lead technical evaluation and integration of new NGS sequencing platforms (e.g., Illumina, Oxford Nanopore) and library prep chemistries onto the automated platform.
Serve as the technical bridge between assay science and automation engineering, translating wet-lab protocols into robust, industrialized, automatable processes.
Partner with Regulatory and Quality to ensure system and workflow changes are appropriately validated and documented for an FDA-cleared diagnostics environment.
Lead technical diligence on new sequencer, automation, and reagent vendor partnerships, including independently assessing vendor-provided integration timelines and effort estimates.
Senior level: 8+ years of hands-on process/automation engineering or systems integration experience in diagnostics, medical device, or another regulated laboratory environment for Senior level; 8–10+ years for Principal level - ideally including work translating early-stage or research-originated protocols into scaled automated production.
Working knowledge of FDA design-control and 510(k) considerations as they apply to system, workflow, and labware changes.
Prior experience in oncology diagnostics (companion diagnostics, comprehensive genomic profiling, or MRD workflows) strongly preferred.
Strong cross-functional communicator, comfortable translating between bench scientists and automation/hardware engineers.
A genuine preference for hands-on, at-the-bench work over slide review - you'll be building and testing systems yourself.

Technical Skills - NGS

Hands-on experience with at least one major NGS sequencing platform (Illumina and/or Oxford Nanopore), including run setup, sequencing chemistry, and flow cell/consumable workflows.
Working knowledge of NGS library preparation chemistries relevant to clinical panels (hybrid capture and/or amplicon-based enrichment).
Experience integrating or supporting a secondary analysis pipeline (e.g., DRAGEN or equivalent) and understanding how upstream lab changes propagate to sequencing QC metrics and analysis output.
Familiarity with NGS assay QC parameters and how automation or platform changes can affect them.

Technical Skills - Automation, Labware & Systems Robustness

Hands-on experience with Hamilton STAR/STAR2 liquid handling platforms, including VENUS software, deck design, and integrating third-party modules.
Demonstrated experience in labware selection, qualification, and DOE-based robustness testing (tolerance analysis, failure-mode analysis) for automated liquid-handling processes.
Strong statistical skills (design of experiments, process capability analysis, hypothesis testing, tolerance stack-up) applied to robustness and verification/validation study design.
Track record translating manual, research-originated wet-lab protocols into production-grade, automatable, robust processes suitable for a regulated environment.
Understanding of how liquid-handling method design and labware selection affect downstream NGS library quality and sequencing performance.
Salary range: $160,808 to $196,544
Medical, dental, and vision insurance
Employer-Sponsored Basic Life/AD&D, Long Term Disability
Employee Assistance Program (EAP)
Discretionary Time Off
Stock Option Plan
Lunch stipend for days at headquarters

Notice of E-Verify Participation: Clear Labs participates in the federal E-Verify program to confirm the identity and employment eligibility of all newly hired employees. For more information, please review the E-Verify Participation Poster (English/Spanish) and the Right to Work Poster (English/Spanish).

Disclaimer: The above job description is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of the Company.