Jobs in the United States

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Added 1 min ago
Principal Quality Engineer
Twenty-Six Defense
Fort Worth, TX
…United States. Twenty-Six Defense is wholly owned by Elbit Systems Ltd. (NASDAQ: ESLT and TASE: ESLT), a global high-technology company engaged in a wide range of programs for innovative…
Added 10 mins ago
Principal AI translation architect 200 languages
Travoom
Remote, United States
You’ll build a conversational commerce platform capable of understanding intent, gathering information from dozens of independent systems, reasoning over the results, ranking…
Added 10 mins ago
Senior Payments Infrastructure Engineer - Crypto, Wallets & Blockchain
Travoom
Remote, United States
We are seeking a hands-on Senior Payments Infrastructure Engineer to take ownership of an existing payments backend and complete its integration, testing, and production deployment.
Added 22 mins ago
AS
Senior Systems Engineer
Andromeda Systems Incorporated
Jacksonville, FL
- $48 to $87 USD / hour
ASI is seeking a Senior Systems Engineer to support DoD aviation programs through reliability analysis, lifecycle sustainment, and readiness assessments. This highly motivated individual…
Added 24 mins ago
Mojo Libraries Engineer (Copy)
Modular
Remote, United States
Bachelor's degree in Engineering, Information Systems, Computer Engineering, Electrical Engineering, Computer Science, or related field and 4+ years of Software Engineering or related work…
Added 30 mins ago
G
Water/Wastewater Engineer
GPAC
Maple Grove, MN
- $85,000 to $140,000 USD / year
A full-time Senior Project Engineer is needed to join an established Water/Wastewater team. This role involves planning, design, and oversight of municipal water and wastewater…
Added 54 mins ago
Principal Systems Engineer
2HB Incorporated
Annapolis Junction, MD
2HB Incorporated is seeking a Principal Systems Engineer to support its government customer in Annapolis Junction, MD. The Principal Systems Engineer will serve as a senior technical leader…
Added 1 hour ago
LN
Senior Project Manager
Luster National
Sacramento, CA
- $140,000 to $200,000 USD / year
We’re seeking Senior Project Managers to support large, complex heavy civil infrastructure programs, including highways, roads, bridges and transit (bus and rail), delivered through both…
Added 1 hour ago
LN
Senior Project Engineer
Luster National
Sacramento, CA
- $120,000 to $200,000 USD / year
We’re seeking Senior Project Engineers to support large, complex heavy civil infrastructure programs, including highways, roads, bridges, and transit (bus and rail), delivered through both…
Added 2 hours ago
Quality Engineer III (QA Systems)
Parker Hannifin Corporation
Lexington, KY
The Quality Engineer III is a senior site-level role responsible for assessing and supporting complex quality performance issues across multiple value streams and functional specialties.…
Added 2 hours ago
SME Network Engineer
CACI International
Ashburn, VA
CACI is seeking a SME Network Engineer for the Global Mission Operations Support (GMOS) contract, supporting the Department of State. This role offers a unique opportunity to enhance…
Added 2 hours ago
Data Engineer, Senior
BOOZ, ALLEN & HAMILTON, INC.
Charlottesville, VA
3+ years of experience supporting operations and maintenance for secure DoW information management systems
Added 2 hours ago
Nuclear Engineer 3 - 31033
HII
Newport News, VA
…fleet. With a holistic approach to life-cycle maritime defense systems-from small watercraft to submarines, surface combatants and aircraft carriers-HII ensures a high state of…
Added 2 hours ago
Nuclear Engineer 4 - 31049
HII
Newport News, VA
…fleet. With a holistic approach to life-cycle maritime defense systems-from small watercraft to submarines, surface combatants and aircraft carriers-HII ensures a high state of…
Added 2 hours ago
Agile Coach and Release Train Engineer
BOOZ, ALLEN & HAMILTON, INC.
Reston, VA
Are you looking for an opportunity to combine your technical systems engineering skills with big picture execution and leadership to make a mission impact and support the warfighter? You…
Added 2 hours ago
Systems Engineer, Senior
BOOZ, ALLEN & HAMILTON, INC.
Herndon, VA
…understand your customer's environment and how to develop the right systems for their mission. Your ability to translate real-world needs into technical specifications, makes you an…
Added 3 hours ago
Senior Automation Engineer
Clear Labs
San Carlos, CA
…software, and wet-lab science together, and we're looking for senior engineers ready to take full ownership of systems, not just advise from the…
Added 3 hours ago
Systems Integration Lead / Process Engineer
Clear Labs
San Carlos, CA
…software, and wet-lab science together, and we're looking for senior engineers ready to take full ownership of systems, not just advise from the…
Added 3 hours ago
Senior Field Service Engineer
Clear Labs
San Carlos, CA
The Senior Field Service Engineer is responsible for supporting both in-house and field installed robotic systems for both proactive and reactive activities as needed. They may also be…
Added 4 hours ago
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Senior Project Engineer Electrical
MSA PROFESSIONAL SERVICES INC
BARABOO, WI
- $142,195 USD / year
Added 4 hours ago
Senior Systems Engineer IBM i
ULINE INC
PLEASANT PRAIRIE, WI
JOB REQUIREMENTS: Senior Systems Engineer - IBM i Corporate Headquarters 12575 Uline Drive, Pleasant Prairie, WI 53158 Keep Uline\'s IBM i systems running seemlessly. As a Senior Systems…
Added 4 hours ago
Senior Cloud Data Engineer
AMERICAN FOODS GROUP LLC
GREEN BAY, WI
Added 4 hours ago
VS
Information Assurance (IA) Lead
VT Services
Aurora, CO
- $195,000 to $220,000 USD / year
In addition to the above relevant IA experience, the Information Assurance Systems Architect and Engineer (IASAE) must also have experience with DoD IA Certification and Accreditation…
Added 4 hours ago
Cyber Security Engineer
Paragon Cyber Solutions
Crane, IN
The Cybersecurity Engineer II supports the implementation, monitoring, and enhancement of enterprise cybersecurity controls. This role contributes to security operations, threat detection,…
Added 5 hours ago
Senior Mechanical Engineer
Central Moloney
Remote, United States
The Mechanical Engineer will be responsible for the mechanical design and development of distribution transformers in compliance with IEEE, CSA, and customer specifications. This role…

Clear Labs

Systems Integration Lead / Process Engineer

San Carlos, CA, United States

Salary range: $160,808 to $196,544

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Job details

Pay: Salary range: $160,808 to $196,544
Posting language: English
Posted: Sep 17, 2026

Original job description

About Clear Labs Clear Labs builds an end-to-end, FDA-cleared next-generation sequencing (NGS) diagnostics platform. Our system, Clear Dx, combines automated sample-to-report workflows with an assay menu spanning oncology and infectious disease testing. We're a hands-on team building hardware, software, and wet-lab science together, and we're looking for senior engineers ready to take full ownership of systems, not just advise from the sidelines.

Position Summary We're hiring a Systems Integration Lead to sit at the interface between assay science and automation engineering - taking benchtop assays and redesigning them into automation-friendly, production-compatible processes. This is a hands-on, senior role responsible for labware qualification, system robustness and guardbanding, and designing and executing acceptance criteria and verification/validation as protocols move from bench to automated production, including closing the current gap where sequencing sits outside our automated oncology workflow as a manual, off-deck step.

Reports to: COO/CSO Location: San Carlos, CA Travel: No travel required.

Primary Responsibilities

Own labware selection, qualification, and system robustness/guardbanding across the automated platform, including DOE-driven robustness testing and failure-mode analysis for automated process steps.
Take benchtop assays developed by the assay science team and redesign them into automation-friendly, production-compatible processes.
Design and execute acceptance criteria and potentially verification/validation protocols as processes move from bench to automated production.
Drive on-deck integration of sequencing into oncology assay workflows, closing the current gap where sequencing runs as a manual, off-deck process outside the automated system.
Lead technical evaluation and integration of new NGS sequencing platforms (e.g., Illumina, Oxford Nanopore) and library prep chemistries onto the automated platform.
Serve as the technical bridge between assay science and automation engineering, translating wet-lab protocols into robust, industrialized, automatable processes.
Partner with Regulatory and Quality to ensure system and workflow changes are appropriately validated and documented for an FDA-cleared diagnostics environment.
Lead technical diligence on new sequencer, automation, and reagent vendor partnerships, including independently assessing vendor-provided integration timelines and effort estimates.
Senior level: 8+ years of hands-on process/automation engineering or systems integration experience in diagnostics, medical device, or another regulated laboratory environment for Senior level; 8–10+ years for Principal level - ideally including work translating early-stage or research-originated protocols into scaled automated production.
Working knowledge of FDA design-control and 510(k) considerations as they apply to system, workflow, and labware changes.
Prior experience in oncology diagnostics (companion diagnostics, comprehensive genomic profiling, or MRD workflows) strongly preferred.
Strong cross-functional communicator, comfortable translating between bench scientists and automation/hardware engineers.
A genuine preference for hands-on, at-the-bench work over slide review - you'll be building and testing systems yourself.

Technical Skills - NGS

Hands-on experience with at least one major NGS sequencing platform (Illumina and/or Oxford Nanopore), including run setup, sequencing chemistry, and flow cell/consumable workflows.
Working knowledge of NGS library preparation chemistries relevant to clinical panels (hybrid capture and/or amplicon-based enrichment).
Experience integrating or supporting a secondary analysis pipeline (e.g., DRAGEN or equivalent) and understanding how upstream lab changes propagate to sequencing QC metrics and analysis output.
Familiarity with NGS assay QC parameters and how automation or platform changes can affect them.

Technical Skills - Automation, Labware & Systems Robustness

Hands-on experience with Hamilton STAR/STAR2 liquid handling platforms, including VENUS software, deck design, and integrating third-party modules.
Demonstrated experience in labware selection, qualification, and DOE-based robustness testing (tolerance analysis, failure-mode analysis) for automated liquid-handling processes.
Strong statistical skills (design of experiments, process capability analysis, hypothesis testing, tolerance stack-up) applied to robustness and verification/validation study design.
Track record translating manual, research-originated wet-lab protocols into production-grade, automatable, robust processes suitable for a regulated environment.
Understanding of how liquid-handling method design and labware selection affect downstream NGS library quality and sequencing performance.
Salary range: $160,808 to $196,544
Medical, dental, and vision insurance
Employer-Sponsored Basic Life/AD&D, Long Term Disability
Employee Assistance Program (EAP)
Discretionary Time Off
Stock Option Plan
Lunch stipend for days at headquarters

Notice of E-Verify Participation: Clear Labs participates in the federal E-Verify program to confirm the identity and employment eligibility of all newly hired employees. For more information, please review the E-Verify Participation Poster (English/Spanish) and the Right to Work Poster (English/Spanish).

Disclaimer: The above job description is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of the Company.