Jobs in the United States

25+ jobs

Save this search

Added 2 mins ago
RQ228116 NCIS Network Engineer | Shift Work | Active TS/SCI clearance
General Dynamics Information Technology
Quantico, VA
Transform technology into opportunity as a Network Engineer with GDIT. A career in enterprise IT means connecting and enhancing the systems that matter most. At GDIT you’ll be at the…
Added 2 mins ago
General Engineer
Defense Logistics Agency
Fort Belvoir, VA
…Requirements Conditions of Employment Qualifications To qualify for a General Engineer your resume and supporting documentation must support: A. Basic Requirement: A Bachelor's Degree or…
Added 2 mins ago
Firewall Operations Engineer
SAIC
Springfield, VA
This is an opening for a Firewall Operations Engineer to support a Department of State (DoS) Bureau of Diplomatic Technology (DT) program. This program provides transparent, interconnected…
Added 2 mins ago
HH
Plant Operator
HCA Healthcare
Reston, VA
- $25.7 to $35.98 USD / hour
Last year our HCA Healthcare colleagues invested over 156,000 hours volunteering in our communities. As a(an) Engineer II with Reston Hospital Center you can be a part of an organization…
Added 2 mins ago
ENGINEER PLANNING ANALYST 4
HII
Newport News, VA
Ability to work independently under general supervision.
Added 2 mins ago
Cloud Solutions Engineer
Office of the Director of National Intelligence
McLean, VA
Summary The Intelligence Community Office of the Inspector General is searching for exceptional candidates to join us in fulfilling our mission to identify and prevent fraud, waste, abuse,…
Added 9 mins ago
Product Engineer, Engineering Applications
Nominal
NY
Some of the world’s leading technology investors, including Sequoia, Lightspeed, Founders Fund, General Catalyst, Lux Capital, and Insight Partners, are backing Nominal’s ambition to change…
Added 32 mins ago
Senior Construction Manager
CLMI Group, LLC
Los Angeles, CA
…to achieve a fair & reasonable price in accordance with the General Conditions; reviews and addresses any and all Schedule impacts in accordance with the project specifications in a timely…
Added 32 mins ago
Construction Manager
CLMI Group, LLC
Los Angeles, CA
…to achieve a fair & reasonable price in accordance with the General Conditions; reviews and addresses any and all Schedule impacts in accordance with the project specifications in a timely…
Added 55 mins ago
Senior Automation Engineer
Clear Labs
San Carlos, CA
We're hiring a Senior Automation Engineer to strengthen the performance, reliability, and validation of the laboratory automation supporting our FDA-cleared NGS diagnostics platform. This…
Added 55 mins ago
Field Service Engineer I/II (San Francisco Bay Area)
Clear Labs
San Carlos, CA
The Field Service Engineer is responsible for supporting both the in-house and field-installed robotic systems. This includes both proactive and reactive activities as needed. They may also…
Added 55 mins ago
Systems Integration Lead / Process Engineer
Clear Labs
San Carlos, CA
Disclaimer: The above job description is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an…
Added 55 mins ago
Senior Field Service Engineer
Clear Labs
San Carlos, CA
The Senior Field Service Engineer is responsible for supporting both in-house and field installed robotic systems for both proactive and reactive activities as needed. They may also be…
Added 56 mins ago
VS
System Engineer
VT Services
Colorado Springs, CO
- $135,000 to $185,000 USD / year
VTG is looking for a System Engineer in Colorado Springs, CO. The Systems Engineer II performs systems engineering tasks with limited supervision, translating mission needs into system…
Added 1 hour ago
Clerk III - Weekend Day Shift
GXO Logistics
Lebanon, IN
We engineer faster, smarter, leaner supply chains.
Added 1 hour ago
Infrastructure Engineer II
EMERGENT HOLDINGS, INC.
NEW BERLIN, WI
Added 1 hour ago
Infrastructure Engineer I
EMERGENT HOLDINGS, INC.
NEW BERLIN, WI
Added 1 hour ago
HVAC Mechanic DPW Building Complex
CITY OF RACINE
RACINE, WI
Added 1 hour ago
Project Engineer, Test
ROCKWELL AUTOMATION INC.
MILWAUKEE, WI
Added 1 hour ago
Sentinel - Systems Engineer (20086)
CORP-Corporate Office
United States
Northrop Grumman Defense Systems is seeking a Systems Engineer to join our team. This position will be located at Roy, UT to support the Sentinel (GBSD) program in the Strategic Deterrent…
Added 1 hour ago
GD
CMSS Advanced Software Engineer (SATCOM and EW)
General Dynamics Mis
Colorado Springs, CO
- $118,519 to $131,482 USD / year
As a software engineer for CMSS , you'll be a member of a cross functional team responsible for analysis and resolution of security findings, design and implement complex system…
Added 1 hour ago
VS
Space Information System Security Engineer (ISSE)
VT Services
Aurora, CO
- $165,000 to $210,000 USD / year
VTG is looking for an Information System Security Engineer (ISSE)s in multiple locations. (Note: position is contingent upon program award and the postions are located in Chantilly VA,…
Added 1 hour ago
VS
Information Assurance (IA) Lead
VT Services
Aurora, CO
- $195,000 to $220,000 USD / year
In addition to the above relevant IA experience, the Information Assurance Systems Architect and Engineer (IASAE) must also have experience with DoD IA Certification and Accreditation…
Added 2 hours ago
CC
Safety Engineer
Chesapeake Contracting Group
Herndon, VA
- $60,000 to $90,000 USD / year
Chesapeake Contracting Group is a value-added commercial general contractor providing services
Added 2 hours ago
CC
Safety Engineer
Chesapeake Contracting Group
Baltimore, MD
- $60,000 to $90,000 USD / year
Chesapeake Contracting Group is a value-added commercial general contractor providing services

Clear Labs

Systems Integration Lead / Process Engineer

San Carlos, CA, United States

Salary range: $160,808 to $196,544

Apply About employer

Applications open in a new tab.

Job details

Pay: Salary range: $160,808 to $196,544
Posting language: English
Posted: Sep 17, 2026

Original job description

About Clear Labs Clear Labs builds an end-to-end, FDA-cleared next-generation sequencing (NGS) diagnostics platform. Our system, Clear Dx, combines automated sample-to-report workflows with an assay menu spanning oncology and infectious disease testing. We're a hands-on team building hardware, software, and wet-lab science together, and we're looking for senior engineers ready to take full ownership of systems, not just advise from the sidelines.

Position Summary We're hiring a Systems Integration Lead to sit at the interface between assay science and automation engineering - taking benchtop assays and redesigning them into automation-friendly, production-compatible processes. This is a hands-on, senior role responsible for labware qualification, system robustness and guardbanding, and designing and executing acceptance criteria and verification/validation as protocols move from bench to automated production, including closing the current gap where sequencing sits outside our automated oncology workflow as a manual, off-deck step.

Reports to: COO/CSO Location: San Carlos, CA Travel: No travel required.

Primary Responsibilities

Own labware selection, qualification, and system robustness/guardbanding across the automated platform, including DOE-driven robustness testing and failure-mode analysis for automated process steps.
Take benchtop assays developed by the assay science team and redesign them into automation-friendly, production-compatible processes.
Design and execute acceptance criteria and potentially verification/validation protocols as processes move from bench to automated production.
Drive on-deck integration of sequencing into oncology assay workflows, closing the current gap where sequencing runs as a manual, off-deck process outside the automated system.
Lead technical evaluation and integration of new NGS sequencing platforms (e.g., Illumina, Oxford Nanopore) and library prep chemistries onto the automated platform.
Serve as the technical bridge between assay science and automation engineering, translating wet-lab protocols into robust, industrialized, automatable processes.
Partner with Regulatory and Quality to ensure system and workflow changes are appropriately validated and documented for an FDA-cleared diagnostics environment.
Lead technical diligence on new sequencer, automation, and reagent vendor partnerships, including independently assessing vendor-provided integration timelines and effort estimates.
Senior level: 8+ years of hands-on process/automation engineering or systems integration experience in diagnostics, medical device, or another regulated laboratory environment for Senior level; 8–10+ years for Principal level - ideally including work translating early-stage or research-originated protocols into scaled automated production.
Working knowledge of FDA design-control and 510(k) considerations as they apply to system, workflow, and labware changes.
Prior experience in oncology diagnostics (companion diagnostics, comprehensive genomic profiling, or MRD workflows) strongly preferred.
Strong cross-functional communicator, comfortable translating between bench scientists and automation/hardware engineers.
A genuine preference for hands-on, at-the-bench work over slide review - you'll be building and testing systems yourself.

Technical Skills - NGS

Hands-on experience with at least one major NGS sequencing platform (Illumina and/or Oxford Nanopore), including run setup, sequencing chemistry, and flow cell/consumable workflows.
Working knowledge of NGS library preparation chemistries relevant to clinical panels (hybrid capture and/or amplicon-based enrichment).
Experience integrating or supporting a secondary analysis pipeline (e.g., DRAGEN or equivalent) and understanding how upstream lab changes propagate to sequencing QC metrics and analysis output.
Familiarity with NGS assay QC parameters and how automation or platform changes can affect them.

Technical Skills - Automation, Labware & Systems Robustness

Hands-on experience with Hamilton STAR/STAR2 liquid handling platforms, including VENUS software, deck design, and integrating third-party modules.
Demonstrated experience in labware selection, qualification, and DOE-based robustness testing (tolerance analysis, failure-mode analysis) for automated liquid-handling processes.
Strong statistical skills (design of experiments, process capability analysis, hypothesis testing, tolerance stack-up) applied to robustness and verification/validation study design.
Track record translating manual, research-originated wet-lab protocols into production-grade, automatable, robust processes suitable for a regulated environment.
Understanding of how liquid-handling method design and labware selection affect downstream NGS library quality and sequencing performance.
Salary range: $160,808 to $196,544
Medical, dental, and vision insurance
Employer-Sponsored Basic Life/AD&D, Long Term Disability
Employee Assistance Program (EAP)
Discretionary Time Off
Stock Option Plan
Lunch stipend for days at headquarters

Notice of E-Verify Participation: Clear Labs participates in the federal E-Verify program to confirm the identity and employment eligibility of all newly hired employees. For more information, please review the E-Verify Participation Poster (English/Spanish) and the Right to Work Poster (English/Spanish).

Disclaimer: The above job description is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of the Company.