Jobs in the United States

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Data Systems Analyst & Infrastructure Modernization Specialist
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Alexandria, VA
…assisting in developing strategic and operational plans for legacy system retirement and elimination; and helping with data center consolidation, resiliency, and optimization initiatives…
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Web Developer
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Chantilly, VA
AWS certification, such as AWS Certified Developer – Associate or AWS Certified DevOps Engineer – Professional.
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ENGINEER TEST OPERATIONS 1
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ENGINEER WELDING 1
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Agile Coach and Release Train Engineer
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…management tools while mentoring team members, Product Managers, System Architects, and Scrum Masters. You will lead multiple pillars from end-to-end and deliver SAFe training and…
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Systems Engineer, Senior
BOOZ, ALLEN & HAMILTON, INC.
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…security space systems by leading agile systems engineering and integration efforts. Your customer will trust you to not only design and develop these systems, but also evolve them with…
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Cloud Solutions Engineer
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Electrical Engineer
BOOZ, ALLEN & HAMILTON, INC.
McLean, VA
As an electrical engineer, you understand the workings behind complex systems. That knowledge is key when it comes to designing RF electronic system components. We're looking for an…
Added 30 mins ago
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Engineer IV - Electrical
CLMI Group, LLC
Los Angeles, CA
- $130,000 to $140,000 USD / year
The Engineer IV – Electrical provides specialized electrical engineering expertise and technical support to the BuildLACCD Sustainability Strike Team throughout the planning, scoping,…
Added 53 mins ago
Senior Automation Engineer
Clear Labs
San Carlos, CA
Clear Labs builds an end-to-end, FDA-cleared next-generation sequencing (NGS) diagnostics platform. Our system, Clear Dx, combines automated sample-to-report workflows with an assay menu…
Added 53 mins ago
DevOps Engineer
ClearlyAgile
Remote, United States
We are hiring an experienced DevOps Engineer to help us support existing and new customers. If you're dedicated, ambitious and have a passion for working with the latest leading edge Cloud…
Added 54 mins ago
VS
System Engineer
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Colorado Springs, CO
- $135,000 to $185,000 USD / year
VTG is looking for a System Engineer in Colorado Springs, CO. The Systems Engineer II performs systems engineering tasks with limited supervision, translating mission needs into system…
Added 57 mins ago
Software Test Engineer II
TGW Systems Inc
Grand Rapids, MI
The Software Test Engineer II is a mid-level engineer who supports a team of Software Engineers in the testing, commissioning, and ongoing support of TGW software solutions.
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Electrical engineer
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Project Engineer, Test
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Data Systems AI / ML Engineer
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Oak Ridge, TN
The Environmental Sciences Division (ESD) at Oak Ridge National Laboratory (ORNL) is seeking a Data Systems AI/ML Engineer for its Earth Sciences Informatics portfolio. In this role, you…
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Sentinel - Systems Engineer (20086)
CORP-Corporate Office
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Northrop Grumman Defense Systems is seeking a Systems Engineer to join our team. This position will be located at Roy, UT to support the Sentinel (GBSD) program in the Strategic Deterrent…
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CMSS Advanced Software Engineer (SATCOM and EW)
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Colorado Springs, CO
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As a software engineer for CMSS , you'll be a member of a cross functional team responsible for analysis and resolution of security findings, design and implement complex system…
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UO
Spacecraft Electrical Power Subsystem (EPS) Lead Engineer
University of Colorado Denver
Boulder, CO
- $145,754 to $229,394 USD / year
The applicant must be a hands-on engineer with strong electrical power system fundamentals and demonstrated experience taking spacecraft hardware through integration, test, and launch. The…
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Space Information System Security Engineer (ISSE)
VT Services
Aurora, CO
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VTG is looking for an Information System Security Engineer (ISSE)s in multiple locations. (Note: position is contingent upon program award and the postions are located in Chantilly VA,…
Added 1 hour ago
UO
Part-Time Electrical Engineer
University of Colorado Denver
Boulder, CO
- $34,986 USD / year
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…atmosphere to trailblazing observations of every planet in the solar system, LASP is at the forefront of solar, planetary and space physics research, space-weather monitoring, and the…
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Information Assurance (IA) Lead
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…engineering the concept, design, development, implementation, and or integration, from end-to-end (E2E), of a system or system…

Clear Labs

Senior Automation Engineer

San Carlos, CA, United States

Salary range: $132,716 to $187,364

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Job details

Pay: Salary range: $132,716 to $187,364
Posting language: English
Posted: Sep 9, 2026

Original job description

About Clear Labs Clear Labs builds an end-to-end, FDA-cleared next-generation sequencing (NGS) diagnostics platform. Our system, Clear Dx, combines automated sample-to-report workflows with an assay menu spanning oncology and infectious disease testing. We're a hands-on team building hardware, software, and wet-lab science together, and we're looking for senior engineers ready to take full ownership of systems, not just advise from the sidelines.

Position Summary We're hiring a Senior Automation Engineer to strengthen the performance, reliability, and validation of the laboratory automation supporting our FDA-cleared NGS diagnostics platform. This is a hands-on, senior role, you'll be at the deck daily, developing methods, troubleshooting hardware, and contributing to formal validation studies alongside our existing automation team.

Location: San Carlos, CA Travel: No travel required.

Primary Responsibilities

Contribute hands-on reliability engineering, method development, and troubleshooting expertise for our Hamilton STAR/STAR2 liquid-handling automation fleet running NGS library preparation workflows.
Help design and execute formal automated-vs-manual equivalence and validation studies for NGS sample prep, in support of regulatory requirements.
Support root-cause investigation for automation performance issues affecting NGS library quality and sequencing output, working through mechanical, calibration, and liquid-class variables systematically, and flagging labware-related findings to Systems Integration for formal qualification.
Partner with Regulatory and Quality on validation protocols and documentation for a regulated, FDA-cleared diagnostics workflow.
Collaborate on vendor and equipment relationships as needed to support fleet performance.
8+ years of hands-on experience programming and developing methods on Hamilton STAR/STAR2 (or directly equivalent) liquid handling platforms, including VENUS software, deck layout design, and liquid class development.
Hands-on troubleshooting of Hamilton hardware and peripherals, e.g., pipetting channels, iSWAP/gripper mechanisms, heater-shakers, plate sealers, and third-party integrated modules.
Experience maintaining and validating a multi-unit automation fleet, including qualifying individual instruments rather than relying on representative sampling.
Ability to independently script and modify automated methods in a regulated environment, with full change-control documentation.
Statistical fluency sufficient to independently evaluate automated performance against validation acceptance criteria.
A genuine preference for hands-on bench and deck work - this is not a delegate-only role.

Nice to Have

Working knowledge of NGS library preparation workflows (e.g., hybrid capture and/or amplicon-based enrichment) as executed on automated liquid handling.
Understanding of how automation method parameters (liquid class, tip type, mixing, incubation) affect NGS library yield, uniformity, and sequencing QC metrics.
Experience troubleshooting automation-driven failures that manifest downstream in sequencing data (e.g., low on-target rate, coverage dropout, well-position-specific effects).
Prior oncology diagnostics experience (NGS-based companion diagnostics or comprehensive genomic profiling workflows).
Salary range: $132,716 to $187,364
Medical, dental, and vision insurance
Employer-Sponsored Basic Life/AD&D, Long Term Disability
Employee Assistance Program (EAP)
Discretionary Time Off
Stock Option Plan
Lunch stipend for days at headquarters

Notice of E-Verify Participation: Clear Labs participates in the federal E-Verify program to confirm the identity and employment eligibility of all newly hired employees. For more information, please review the E-Verify Participation Poster (English/Spanish) and the Right to Work Poster (English/Spanish).

Disclaimer: The above job description is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of the Company.