Jobs in the United States

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Added 10 mins ago
LH
Part Time - Outlet Customer Service Associate - Flexible
Lowe's Home Centers, LLC
Westchester, FL
- Part-time
Generates leads for Project Specialist Exterior (PSE) programs by actively engaging
Added 10 mins ago
LH
Full Time - Sales Specialist - Appliances - Day
Lowe's Home Centers, LLC
Walton, KY
- Full-time
Whether you need a part-time position or a place to plant yourself and grow, Lowe's is ready to support your goals. As a Lowe's associate, you'll gain access to a variety of benefits beyond…
Added 10 mins ago
LH
Full Time - Merchandising Service Associate - Day
Lowe's Home Centers, LLC
Tulsa, OK
- Full-time
Whether you need a part-time position or a place to plant yourself and grow, Lowe's is ready to support your goals. As a Lowe's associate, you'll gain access to many benefits beyond…
Added 10 mins ago
LH
Full Time - Merchandising Service Associate - Day
Lowe's Home Centers, LLC
Stow, OH
- Full-time
Whether you need a part-time position or a place to plant yourself and grow, Lowe's is ready to support your goals. As a Lowe's associate, you'll gain access to many benefits beyond…
Added 10 mins ago
LH
Full Time - Sales Specialist - Flooring - Day
Lowe's Home Centers, LLC
Staunton, VA
- Full-time
Whether you need a part-time position or a place to plant yourself and grow, Lowe's is ready to support your goals. As a Lowe's associate, you'll gain access to a variety of benefits beyond…
Added 10 mins ago
LH
Full Time - Sales Specialist - ProServices - Day
Lowe's Home Centers, LLC
Spokane, WA
- Full-time
…exceptional benefits and wellness programs for eligible full-time and part-time associates, tailored for many different lifestyles. Our benefits range from health, vision and dental…
Added 10 mins ago
LH
Full Time - Merchandising Service Associate - Day
Lowe's Home Centers, LLC
Pocatello, ID
- Full-time
Whether you need a part-time position or a place to plant yourself and grow, Lowe's is ready to support your goals. As a Lowe's associate, you'll gain access to many benefits beyond…
Added 10 mins ago
LH
Full Time - Sales Specialist - Appliances - Day
Lowe's Home Centers, LLC
Pineville, LA
- Full-time
Whether you need a part-time position or a place to plant yourself and grow, Lowe's is ready to support your goals. As a Lowe's associate, you'll gain access to a variety of benefits beyond…
Added 10 mins ago
LH
Full Time - Merchandising Service Associate - Day
Lowe's Home Centers, LLC
Orangeburg, SC
- Full-time
Whether you need a part-time position or a place to plant yourself and grow, Lowe's is ready to support your goals. As a Lowe's associate, you'll gain access to many benefits beyond…
Added 10 mins ago
LH
Full Time - Merchandising Service Associate - Day
Lowe's Home Centers, LLC
Mt Juliet, TN
- Full-time
Whether you need a part-time position or a place to plant yourself and grow, Lowe's is ready to support your goals. As a Lowe's associate, you'll gain access to many benefits beyond…
Added 10 mins ago
LH
Full Time - Sales Specialist - Flooring - Day
Lowe's Home Centers, LLC
Milford, OH
- Full-time
Whether you need a part-time position or a place to plant yourself and grow, Lowe's is ready to support your goals. As a Lowe's associate, you'll gain access to a variety of benefits beyond…
Added 10 mins ago
Early Careers New Grad - Sales/Account Associate (Montana)
Health Care Service Corp.
Helena, MT
Join HCSC and be part of a purpose-driven company that will invest in your professional development.
Added 10 mins ago
Human Subjects Research Scientist (Ph.D.)
Exponent Inc.
Natick, MA
…based in our Natick, MA office. In this role, you will work as part of a team to run data collection, engineering, and analysis for large-scale studies involving human subjects in the…
Added 10 mins ago
LH
Full Time - Merchandising Service Associate - Day
Lowe's Home Centers, LLC
Lynchburg, VA
- Full-time
Whether you need a part-time position or a place to plant yourself and grow, Lowe's is ready to support your goals. As a Lowe's associate, you'll gain access to many benefits beyond…
Added 10 mins ago
LH
Full Time - Merchandising Service Associate - Day
Lowe's Home Centers, LLC
Louisville, KY
- Full-time
Whether you need a part-time position or a place to plant yourself and grow, Lowe's is ready to support your goals. As a Lowe's associate, you'll gain access to many benefits beyond…
Added 10 mins ago
LH
Full Time - Merchandising Service Associate - Day
Lowe's Home Centers, LLC
Humble, TX
- Full-time
Whether you need a part-time position or a place to plant yourself and grow, Lowe's is ready to support your goals. As a Lowe's associate, you'll gain access to many benefits beyond…
Added 10 mins ago
LH
Part Time - Loader/Cart Associate - Flexible
Lowe's Home Centers, LLC
Erwin, NC
- Part-time
Assists customers with locating, selecting, carrying, and loading merchandise while responding promptly to customers and associate questions
Added 10 mins ago
LH
Full Time - Sales Specialist - Appliances - Day
Lowe's Home Centers, LLC
Euless, TX
- Full-time
Whether you need a part-time position or a place to plant yourself and grow, Lowe's is ready to support your goals. As a Lowe's associate, you'll gain access to a variety of benefits beyond…
Added 10 mins ago
LH
Full Time - Sales Specialist - Appliances - Day
Lowe's Home Centers, LLC
Dallas, TX
- Full-time
Whether you need a part-time position or a place to plant yourself and grow, Lowe's is ready to support your goals. As a Lowe's associate, you'll gain access to a variety of benefits beyond…
Added 10 mins ago
LH
Full Time - Sales Specialist - ProServices - Day
Lowe's Home Centers, LLC
Dayville, CT
- Full-time
…exceptional benefits and wellness programs for eligible full-time and part-time associates, tailored for many different lifestyles. Our benefits range from health, vision and dental…
Added 10 mins ago
LH
Full Time - Merchandising Service Associate - Day
Lowe's Home Centers, LLC
Burlington, NC
- Full-time
Whether you need a part-time position or a place to plant yourself and grow, Lowe's is ready to support your goals. As a Lowe's associate, you'll gain access to many benefits beyond…
Added 10 mins ago
LH
Part Time - Loader/Cart Associate - Opening
Lowe's Home Centers, LLC
Bedford, NH
- Part-time
Assists customers with locating, selecting, carrying, and loading merchandise while responding promptly to customers and associate questions
Added 11 mins ago
A
Laboratory Technician
Actalent
Johnston, IA
- $20 USD / hour
Collaborate with laboratory staff and technical personnel to meet project timelines and team objectives.
Added 18 mins ago
L
Part Time - Outlet Customer Service Associate - Flexible
Lowes
Miami, FL
- Part-time
Generates leads for Project Specialist Exterior (PSE) programs by actively engaging
Added 18 mins ago
L
Full Time - Merchandising Service Associate - Day
Lowes
Louisville, KY
- Full-time
Whether you need a part-time position or a place to plant yourself and grow, Lowe's is ready to support your goals. As a Lowe's associate, you'll gain access to many benefits beyond…

Broad Institute

Postdoctoral Associate - Hwang Lab

Cambridge, MA, United States

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Job details

Working hours: 40 hour per week
Posting language: English

Original job description

The Hwang laboratory at the Broad Institute of MIT & Harvard is seeking a highly motivated postdoctoral associate to investigate the host genetic landscape of human papillomavirus (HPV)-driven cellular immortalization and transformation. Infection with 'high-risk' HPVs causes cervical cancer, oropharyngeal cancer, and other anogenital cancers. Although vaccination could prevent the majority of high-risk HPV infections, vaccine uptake rates remain low in many parts of the world, and HPV vaccination cannot treat precancerous lesions or cancers. Therefore, HPV-associated cancers present an urgent public health need: in 2022 alone, there were about 660,000 new cases of cervical cancer and about 350,000 deaths worldwide, making it the fourth leading cause of cancer and cancer deaths in women. The essential drivers of HPV-mediated carcinogenesis are the HPV E6 and E7 oncoproteins, and inhibiting key transforming activities of these oncoproteins has high potential to treat HPV-positive cancers.

To understand and ultimately inhibit HPV-driven carcinogenesis, our team has performed genome-scale CRISPRi and CRISPRa screens in primary human cells, and the project is now advancing to validating and mechanistically characterizing screen hits. The successful candidate will join the project at this exciting stage: leading the hit validation and downstream mechanistic studies, completing the ongoing sub-pool screens, and driving the resulting manuscripts, with ample opportunity to develop independent follow-up directions.

The applicant will be expected to work well in a multi-institute collaboration setting, communicate effectively, and possess a strong desire to contribute to basic and translational research. Training and expertise in virology and functional genomics are essential. This opportunity is particularly suited for candidates who are passionate about research on host-pathogen interactions, especially virus-induced cancers.

Our team is ideally seeking a candidate with:

· A PhD in virology, microbiology, genetics, immunology, or a closely related field · A record of leading projects successfully through publications in scientific journals and presentations at scientific conferences · A solid understanding of and hands-on experience in functional genomics, including CRISPR screens (CRISPRi/CRISPRa), molecular cloning, lentivirus production, and next-generation sequencing · Experience in virology assays and in handling and modulating primary human cells in the presence and absence of infection · Bioinformatic analysis of screen and sequencing data is a big plus

Key Responsibilities:

· Work independently and with team members to design and carry out experiments essential to the individual project and the group's collective success. · Lead the validation and mechanistic characterization of hits from CRISPRi/CRISPRa screens. · Consult the literature, supervisor, and other scientific staff as needed to troubleshoot experiments. · Investigate, learn, and develop new methods and technologies that might be relevant to the project. · Maintain and share detailed experimental records, documentation, and written protocols with team members. · Contribute to grants, papers, and patents.

Required Skills:

· Excellent communication (oral and written) and wet lab skills, organization, and time management skills. · High level of initiative and motivation; ability to work independently and with a team. · Strong desire to learn new methods and ability to think creatively to solve problems.

The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law.

At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits.

The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.

Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.

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More about this job

Skills

Research
Presentation skills
Work independently
Troubleshoot
Documentation
Communication skills
Time management
Think creatively
Compensation and benefits

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