Jobs in the United States

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Senior .Net Developer (Software Development Specialist 4 - PN 20014439)
State of Ohio
Columbus, OH
- $46 to $48.28 USD / hour
The Office of Management Information Systems (OMIS) delivers and supports the technology solutions that power critical public health services across Ohio. Our team builds modern, secure,…
Added 2 mins ago
A
Customer Service Rep II - Part Time (20 hours a week)
AECOM
Remote, United States
- $22 to $30 USD / hour
- Part-time
…planners, designers, engineers, scientists, digital innovators, program and construction managers and other professionals delivering projects that create a positive and tangible impact…
Added 4 mins ago
Senior Member Services Officer
State Employees' Credit Union
United States
Completion of Consumer Lending Program (CLP) courses. Passing score on CLP Exam required prior to becoming a Member Services Officer.
Added 4 mins ago
Member Services Representative
State Employees' Credit Union
United States
Bachelor’s degree, or CCUE Certification, or Associate of Arts degree or Associate of Science degree via the North Carolina Community College Transfer Program (NC-CTP).
Added 4 mins ago
Associate Member Services Representative
State Employees' Credit Union
United States
The Associate Member Services Representative (MSR) is an entry-level position intended to provide team members with foundational knowledge of SECU branch operations. Associate MSRs perform…
Added 4 mins ago
Associate Member Services Representative
State Employees' Credit Union
United States
The Associate Member Services Representative (MSR) is an entry-level position intended to provide team members with foundational knowledge of SECU branch operations. Associate MSRs perform…
Added 4 mins ago
Contractor - Scrum Master - Remote US
SAMC SitusAMC Holdings Corp
Remote, United States
…eligible to receive a discretionary bonus as determined by bonus program guidelines, position eligibility and SitusAMC Senior Management approval. SitusAMC offers PTO and paid holidays, the…
Added 5 mins ago
BM
Hiring Now: Preschool Teacher
Bambini Montessori Academy
Gambrills, MD
- $18 to $21 USD / hour
At Bambini Childcare, we are proud to provide a high-quality, inclusive early childhood program for children ages 6 weeks to 5 years old. We believe every child deserves a safe, nurturing,…
Added 5 mins ago
BM
Hiring Now: Preschool Teacher (Part-Time)
Bambini Montessori Academy
Ellicott City, MD
- $18 to $21 USD / hour
- Part-time
Bambini Childcare is a high-quality, inclusive early childhood program serving children ages 6 weeks to 5 years old. Be part of a nurturing environment where your passion for teaching helps…
Added 5 mins ago
Software Engineer
teKnoluxion
Valley Forge, PA · Herndon, VA
Provide on-site support to customer partner program as an integrated builder on a partner development team.
Added 5 mins ago
Assistant Store Manager
Community Choice Financial Family of Brands
Pulaski, TN
…providing an ongoing comprehensive training and development program that will allow you to truly…
Added 5 mins ago
Assistant Store Manager
Community Choice Financial Family of Brands
Lavergne, TN
…providing an ongoing comprehensive training and development program that will allow you to truly…
Added 6 mins ago
Retail Co-Store Manager
Ollie's Bargain Outlet
Manassas, VA
20% associate discount on all Ollie’s purchases & quarterly bonus program.
Added 6 mins ago
Retail Store Manager
Ollie's Bargain Outlet
Clovis, NM
20% Associate discount on all Ollie’s purchases and bi-annual & annual bonus program.
Added 6 mins ago
Outside Sales Associate
State Industrial Products
Atlantic City, NJ
…auxiliary programs, State Industrial Products offers facility management benefits that are second to none. We’re a thriving company, and we’re looking for driven individuals to join our…
Added 6 mins ago
Retail Store Manager
Ollie's Bargain Outlet
Little Rock, AR
20% Associate discount on all Ollie’s purchases and bi-annual & annual bonus program.
Added 6 mins ago
Executive Administrative Assistant - Government Resource Center
The Ohio State University
United States
…manages complex administrative functions for the Director and Associate Director of the GRC, including calendar and meeting management, executive communications, document preparation and…
Added 6 mins ago
TO
Assistant Dining Manager
The Ohio State University
United States
- $17.69 to $22.96 USD / hour
Desired: Associate's degree in hospitality management or related field; 6 years relevant experience; knowledge of ServSafe Sanitation guidelines or similar food handler program; experience…
Added 8 mins ago
Field Equipment Installer
Party Reflections Operations, Inc.
Greensboro, NC
Joining Party Reflections as a Field Associate and event installer gives you the ability to:
Added 9 mins ago
Associate Director/Director, S2P Contracting COE
Eli Lilly Cork Limited
Remote, United States
…medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our…
Added 9 mins ago
Senior Director, Global Market Research - Immunology
Lilly USA, LLC
United States
…medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our…
Added 10 mins ago
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Retail Stocking Team Supervisor - Full-Time
Burlington
Walla Walla, WA
- $19.13 to $21.13 USD / hour
- Full-time
…part of the store leadership team, working closely with Store Management while being the main leader and director of the Back of House area. This leadership position is the stepping-stone…
Added 10 mins ago
Supply Base Manager
The Boeing Company
Tukwila, WA
Boeing Defense, Space & Security (BDS) has an exciting opportunity for an Associate or Experienced Supply Base Management Specialist to join our P-8 Supply Chain Team in Tukwila, WA .
Added 10 mins ago
CG
WAREHOUSE ATTENDANT (FULL TIME)
Compass Group, North America
BOTHELL, WA
- $22 to $24 USD / hour
- Full-time
Full-time and part-time positions offer the following benefits to associates: Retirement Plan, Associate Shopping Program, Health and Wellness Programs, Discount Marketplace, Identity Theft…
Added 10 mins ago
CB
Process Engineer
Conagra Brands
Kent, WA
- $81,000 to $95,000 USD / year
…continuous improvement within the Business Unit by leading Daily Management Systems, improving equipment reliability, advancing digital tools, and developing team capability. You will…

Broad Institute

Postdoctoral Associate - Hwang Lab

Cambridge, MA, United States

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Job details

Working hours: 40 hour per week
Posting language: English

Original job description

The Hwang laboratory at the Broad Institute of MIT & Harvard is seeking a highly motivated postdoctoral associate to investigate the host genetic landscape of human papillomavirus (HPV)-driven cellular immortalization and transformation. Infection with 'high-risk' HPVs causes cervical cancer, oropharyngeal cancer, and other anogenital cancers. Although vaccination could prevent the majority of high-risk HPV infections, vaccine uptake rates remain low in many parts of the world, and HPV vaccination cannot treat precancerous lesions or cancers. Therefore, HPV-associated cancers present an urgent public health need: in 2022 alone, there were about 660,000 new cases of cervical cancer and about 350,000 deaths worldwide, making it the fourth leading cause of cancer and cancer deaths in women. The essential drivers of HPV-mediated carcinogenesis are the HPV E6 and E7 oncoproteins, and inhibiting key transforming activities of these oncoproteins has high potential to treat HPV-positive cancers.

To understand and ultimately inhibit HPV-driven carcinogenesis, our team has performed genome-scale CRISPRi and CRISPRa screens in primary human cells, and the project is now advancing to validating and mechanistically characterizing screen hits. The successful candidate will join the project at this exciting stage: leading the hit validation and downstream mechanistic studies, completing the ongoing sub-pool screens, and driving the resulting manuscripts, with ample opportunity to develop independent follow-up directions.

The applicant will be expected to work well in a multi-institute collaboration setting, communicate effectively, and possess a strong desire to contribute to basic and translational research. Training and expertise in virology and functional genomics are essential. This opportunity is particularly suited for candidates who are passionate about research on host-pathogen interactions, especially virus-induced cancers.

Our team is ideally seeking a candidate with:

· A PhD in virology, microbiology, genetics, immunology, or a closely related field · A record of leading projects successfully through publications in scientific journals and presentations at scientific conferences · A solid understanding of and hands-on experience in functional genomics, including CRISPR screens (CRISPRi/CRISPRa), molecular cloning, lentivirus production, and next-generation sequencing · Experience in virology assays and in handling and modulating primary human cells in the presence and absence of infection · Bioinformatic analysis of screen and sequencing data is a big plus

Key Responsibilities:

· Work independently and with team members to design and carry out experiments essential to the individual project and the group's collective success. · Lead the validation and mechanistic characterization of hits from CRISPRi/CRISPRa screens. · Consult the literature, supervisor, and other scientific staff as needed to troubleshoot experiments. · Investigate, learn, and develop new methods and technologies that might be relevant to the project. · Maintain and share detailed experimental records, documentation, and written protocols with team members. · Contribute to grants, papers, and patents.

Required Skills:

· Excellent communication (oral and written) and wet lab skills, organization, and time management skills. · High level of initiative and motivation; ability to work independently and with a team. · Strong desire to learn new methods and ability to think creatively to solve problems.

The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law.

At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits.

The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.

Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.

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More about this job

Skills

Research
Presentation skills
Work independently
Troubleshoot
Documentation
Communication skills
Time management
Think creatively
Compensation and benefits

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