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Added 1 min ago
Senior Software Engineer
Emergent Software
Remote, United States
…purchase and managing ongoing ownership. They are seeking a Senior Software Engineer to design, build, and evolve customer-facing features, services, and systems that power this experience.…
Added 1 min ago
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Sr. QA/Test Automation Engineer
Jobot
Gaithersburg, MD
- $140,000 to $175,000 USD / year
Senior QA / Test Automation Engineer – Senior, Lead & Principal Levels
Added 1 min ago
Senior Software Engineer
Applied Materials, Inc
Santa Clara, CA
We are looking for an experienced Senior Software Engineer to design and develop scalable, high-performance software solutions for complex, data-intensive applications.
Added 4 mins ago
O
Lead Principal Application Software Engineer- Forward Deployed Engineer
Oracle
Trenton, NJ
- $104,600 to $264,100 USD / year
Oracle Customer Success Services (CSS) is seeking a Senior Principal Forward Deployed Engineer to lead the delivery of strategic AI and data transformation programs for Oracle's largest…
Added 14 mins ago
Senior Software Engineer, Axon 911 (Relocation Assistance Available)
Axon
NY
Strong understanding of distributed systems and event-driven architectures.
Added 19 mins ago
K
Remote Senior Golang Engineer
Kforce
Remote, United States
- $150,000 to $170,000 USD / year
Senior Golang Engineer will design, develop, and maintain scalable backend applications and services
Added 27 mins ago
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Staff Software Engineer, AI & Platform
Arketa
New York City, NY
- $180,000 to $240,000 USD / year
You'll join a small, senior, fully distributed engineering team. We operate with high autonomy and very little process: a customer asks for something Monday, it's built Tuesday, shipped…
Added 34 mins ago
Senior Software Development Engineer, Amazon Quick
Amazon Web Services, Inc.
Seattle, WA
As a lead software development engineer on the Amazon Quick team, you will design and develop features for the Amazon Quick product. You will work with senior scientists and engineers…
Added 35 mins ago
Systems Engineer
Astraeus Operations LLC
UNAVAILABLE, VA
The Systems Engineer provides on-site, 24/7/365 Tier 1 operations for Google Public Sector’s USG1 sovereign and classified cloud environments, initially supporting Google Distributed Cloud…
Added 41 mins ago
Senior Software Engineer - Java Cloud (Health100 Platform)
CVS Shared Services Resources LLC
Remote, United States
As a Senior Software Engineer for Health100, you will play a crucial role within a collaborative team - designing, developing, and maintaining backend services and APIs while ensuring…
Added 44 mins ago
Palo Alto Integration Engineer - Mid
VIATEQ Corporation
Washington, DC
The ideal candidate is a technically proficient and security-focused network security engineer with solid, hands-on experience across key Palo Alto Networks platforms - including…
Added 50 mins ago
Senior Dynatrace Observability Engineer / Subject Matter Expert (SME)
Derex Technologies Inc
Remote, United States
Position: Senior Dynatrace Observability Engineer / Subject Matter Expert (SME)
Added 51 mins ago
Senior Staff Software Engineer, Platform
Rippling
San Francisco, CA · Seattle, WA · New York, NY
As a Senior Staff Engineer, you'll help define the architecture that powers both Rippling's platform and its next generation of AI-native products. You'll solve distributed systems…
Added 54 mins ago
Senior IT Collaboration and Communication Engineer
Premise Health
Brentwood, TN
This is a Full Time, hybrid, Senior IT Collaboration and Communication Engineer role located in Brentwood, TN.
Added 54 mins ago
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Product Software Engineer II
Disney Entertainment & Sports LLC
Glendale, CA
- $117,500 to $157,500 USD / year
Understanding of message-based distributed, scalable, and resilient systems
Added 54 mins ago
Senior Software Engineer
Alder
Newton, MA
Deep understanding of scalability in distributed systems, performance optimization, caching, and database design.
Added 57 mins ago
Network Engineer 5 (DNS | DHCP | IPAM)
Capital One
McLean, VA · Plano, TX · Richmond, VA
…frameworks and emerging technologies to join our team. As a Network Engineer, you’ll have the opportunity to be on the forefront of driving a major transformation across Capital…
Added 57 mins ago
Customer Reference Specialist
ServiceNow
Remote, United States
It all started when engineer Fred Luddy wrote code that automated a tedious task for his coworker, Phyllis. She cried tears of joy. That moment inspired Fred to build a company that could…
Added 1 hour ago
Data Engineer III (US)
TD Bank, N.A.
Mount Laurel, NJ
Lead / Tech Lead / Senior Engineer: Demonstrated experience operating as a Lead Engineer, Technical Lead, Senior Engineer, or equivalent senior technical role, providing technical direction…
Added 1 hour ago
Lead Site Reliability Engineer
Charles Schwab Inc.
Austin, TX
Knowledge of distributed systems, microservices, high-availability architectures, and messaging technologies such as Kafka or RabbitMQ.
Added 1 hour ago
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Senior Staff Data Engineer
Biohub
NY · Redwood City, CA
- $270,000 to $300,000 USD / year
As a Senior Staff Data Engineer at Biohub, you'll be designing systems that ingest data from public repositories, transform heterogeneous biological formats into AI-ready datasets, combine…
Added 1 hour ago
Systems Engineer
Astraeus Operations LLC
UNAVAILABLE, VA
The Systems Engineer provides on-site, 24/7/365 Tier 1 operations for Google Public Sector’s USG2 sovereign and classified cloud environments, initially supporting Google Distributed Cloud…
Added 1 hour ago
Senior Operations Lead
Astraeus Operations LLC
UNAVAILABLE, VA
The Senior Operations Lead provides on-site technical floor leadership for Google Public Sector’s USG1 Intelligence Community sovereign and classified cloud operations, initially supporting…
Added 1 hour ago
Senior Operations Lead
Astraeus Operations LLC
UNAVAILABLE, VA
The Senior Operations Lead provides on-site technical floor leadership for Google Public Sector’s USG2 Intelligence Community sovereign and classified cloud operations, initially supporting…
Added 1 hour ago
Software Development Engineer, Alexa Sensitive Content Intelligence (ASCI)
Amazon.com Services LLC
Bellevue, WA
We seek a Software Development Engineer (SDE) II who is highly motivated, owns outcomes end-to-end, and thrives in a fast-paced, collaborative environment that adopts AI and leverages…

Biohub

Senior Staff Data Engineer

NY, United States
Redwood City, CA, United States

$270,000 to $300,000 USD / year

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Job details

Pay: $270,000 to $300,000 USD / year
Experience: 12+ years of experience building reliable, operable data systems at petabyte scale
Posting language: English
Posted: Nov 2, 2026

Original job description

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.

The Team

Biohub is a 501(c)(3) biomedical research organization building the first large-scale scientific initiative combining frontier AI with frontier biology to solve disease. We build the technology to help scientists around the world use AI-powered biology to study how cells operate, organize, and work as part of systems to understand why disease happens and how to correct it. With our compute capacity, AI research and engineering, and state-of-the-art technology for measuring, imaging, and programming biology, we are enabling scientists worldwide to use AI-powered biology to advance our understanding of human health.

The Opportunity

The role is part of the Data Engineering team, which focuses on owning the strategy, sourcing and implementation for data supporting AI research and development. Our goal is to maximize the speed, agility, and capability of biological AI research by connecting public data resources and Biohub's experimental platforms to AI systems. The data that trains biological frontier models comes in dozens of modalities (sequences, images, spatial coordinates, time series, molecular structures, metadata, publication artifacts) each with its own noise characteristics, biases, and information content. The question of how to represent this data for learning is one of the most important open problems in biological AI.

As a Senior Staff Data Engineer at Biohub, you'll be designing systems that ingest data from public repositories, transform heterogeneous biological formats into AI-ready datasets, combine that with proprietary datasets, and deliver training datasets to researchers pushing the boundaries of what's possible in biological AI. The infrastructure you build will directly shape what our models can learn.

We're a small team with significant resources and long time horizons. We use AI tools aggressively in our own work - Claude Code, agents for workflow automation, LLMs for metadata extraction. We care about code quality, operational reliability, and building systems that scale. And we care about the biology: we want engineers who can recognize when a pipeline output is technically correct but scientifically wrong.

If you want to work at the intersection of large-scale infrastructure and frontier science, with real autonomy and the chance to build something genuinely new, we'd like to talk.

What You'll Do

Design and build data pipelines that process genomic and imaging data at petabyte scale
Solve performance and bandwidth challenges with creative engineering
Build agent-based systems for automated dataset curation, quality control, and workflow generation
Create tooling for data cataloging and registration that makes datasets discoverable and accessible
Collaborate with AI Research teams to translate model requirements into data specifications, and with our scientists to integrate public and internal data into large-scale ai-ready datasets
Improve pipeline reliability and observability, working toward 99%+ success rates without manual intervention

What You'll Bring

12+ years of experience building reliable, operable data systems at petabyte scale
Strong software engineering fundamentals
Experience deploying distributed computing frameworks like Databricks, Spark, or Ray for large-scale data processing
Experience building and deploying large scale data platform solutions using infrastructure as code like Terraform or CDK
Experience with cloud infrastructure (AWS preferred) and on prem infrastructure
Comfort with ambiguity; ability to make progress when requirements are evolving
Interest in AI-native development practices and tooling
Nice to have: Background in computational biology, bioinformatics, or life sciences and experience with genomics datasets and formats (FASTQ, BAM, VCF) or imaging formats (OME-Zarr, HDF5)

Compensation

The anticipated base pay ranges for this role in Redwood City, CA and New York City, NY is $270,000–$300,000 annually for the Senior Staff level. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process. This position may be eligible to participate in Biohub's discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with Biohub's total rewards philosophy and may vary by role.

Better Together

As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager's discretion and communicated during the interview process.

Benefits for the Whole You

We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.

Provides a generous employer match on employee 401(k) contributions to support planning for the future.
Paid time off to volunteer at an organization of your choice.
Funding for select family-forming benefits.
Relocation support for employees who need assistance moving

If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.

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