Jobs in the United States

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Added 4 mins ago
Principal Radar / RF Electrical Subsystems Engineer
RTX Corporation
tucson, AZ
The Advanced Effectors Guidance Systems department is seeking a Principal Radar / RF-focused Electrical Subsystems Engineer with deep experience in RF subsystem design, radar development,…
Added 4 mins ago
Sr. Principal Radar / RF Electrical Subsystems Engineer
RTX Corporation
tucson, AZ
The Advanced Effectors Guidance Systems department is seeking a Sr Principal Radar / RF-focused Electrical Subsystems Engineer with deep experience in RF subsystem design, radar…
Added 4 mins ago
Senior Software Safety / Senior System Safety Engineer
RTX Corporation
tucson, AZ
…risks, and implement solutions to enhance product safety and reliability for our…
Added 4 mins ago
Software / System Safety Engineer II
RTX Corporation
tucson, AZ
…risks, and implement solutions to enhance product safety and reliability for our…
Added 4 mins ago
Principal Digital Factory Engineer IV
RTX Corporation
tucson, AZ
We are seeking a Principal Digital Factory Engineer to design, develop, integrate, and support advanced digital factory solutions deployed across multiple Raytheon manufacturing sites. This…
Added 4 mins ago
O
Sr Software Engineer - Cloud Automation & AI Systems
Oracle
Phoenix, AZ
- $89,200 to $209,500 USD / year
Software Engineer 3 – Cloud Automation & AI Systems
Added 4 mins ago
Autonomous Hauling Technology Consultant
Caterpillar, Inc.
Phoenix, AZ
Serve as trusted advisor to customer teams on all aspects of system performance, reliability, and fleet optimization, with a strong focus on optimize performance.
Added 4 mins ago
O
Senior Core Infrastructure Engineer- Nashville,TN
Oracle
Phoenix, AZ
- $79,200 to $209,500 USD / year
Help identify and remediate security, reliability, and operational risks.
Added 4 mins ago
PN
Senior Databricks Engineer
Pacific Northwest National Laboratory
Phoenix, AZ
- $133,100 USD / year
We are seeking an experienced Databricks Engineer to support the design, build, and operation of our enterprise data lakehouse that powers analytics and reporting across PNNL systems. This…
Added 4 mins ago
Software Engineer, CDP - Stablecoin
Coinbase
Phoenix, AZ
…growth, and ecosystem expansion at Coinbase. As a Software Engineer, you'll help deliver a suite of international stablecoins by evaluating and integrating external partner APIs, building…
Added 4 mins ago
Sr. Machine Learning Engineer (Remote)
CrowdStrike
Phoenix, AZ
CrowdStrike is looking for a Sr. Machine Learning Engineer to join our growing AIDR Engineering Team. You will provide engineering support and solutions to a data science group focused on…
Added 4 mins ago
Software Test Engineer
WCG Clinical
Phoenix, AZ
The Software Test Engineer is a member of the Quality Engineering team, responsible for supporting the testing, validation and delivery of WCG namedproducts and systems.The role applies…
Added 4 mins ago
Senior Azure Infrastructure Engineer (Remote: US & Canada)
Cytel
Phoenix, AZ
We are seeking a highly skilled and experienced Senior Azure Engineer to join our cloud engineering team. This role is for a hands-on technical contributor who will design, implement,…
Added 4 mins ago
AT
Senior II Site Reliability Engineer
Akamai Technologies, Inc.
Phoenix, AZ
- $146,400 to $263,600 USD / year
As a Senior II Site Reliability Engineer, you will be responsible for:
Added 4 mins ago
AT
Senior II Site Reliability Engineer
Akamai Technologies, Inc.
Phoenix, AZ
- $146,400 to $263,600 USD / year
As a Senior Site Reliability Engineer, you will be responsible for:
Added 4 mins ago
AT
Site Reliability Engineer II
Akamai Technologies, Inc.
Phoenix, AZ
- $95,000 to $171,000 USD / year
As a Site Reliability Engineer II, you will be responsible for:
Added 4 mins ago
Senior Engineer, Google Cloud
PwC
Phoenix, AZ
As a Senior Engineer, Google Cloud you will focus on building, testing, and optimizing cloud-native applications on Google Cloud, supporting work that spans the full software development…
Added 4 mins ago
Principal Mechanical Design Engineer
Honeywell Aerospace
Phoenix, AZ
As a Principal Mechanical Design Engineer here at Honeywell Aerospace, you will be a key contributor to the design and development of cutting-edge mechanical solutions. You will play a…
Added 6 mins ago
Principal Navigation Engineer
Mach Industries
Huntington Beach, CA
Mach Industries is seeking a Principal Navigation Engineer to lead the development, integration, and flight validation of navigation systems for autonomous aircraft and related defense…
Added 6 mins ago
Senior Application Tester
VTG
Chantilly, VA
We are seeking a Software Test Engineer to support the quality and reliability of web applications built with React, TypeScript, and Node.js. This role will develop and execute testing…
Added 6 mins ago
Sr. Software Engineer - Back-End
VTG
Chantilly, VA
We are seeking a Senior Software Engineer with extensive development experience to build backend software, analyze existing applications, and develop automated testing capabilities. This…
Added 22 mins ago
O
Principal Core Infrastructure Engineer (Nashville, TN, relo provided)
Oracle
Nashville, TN
- $114,600 to $234,600 USD / year
System Design & Architecture - System Reliability Design:
Added 22 mins ago
O
Principal Core Infrastructure Engineer (Nashville, TN, relo assistance available)
Oracle
Nashville, TN
- $114,600 to $234,600 USD / year
System Design & Architecture - System Reliability Design:
Added 27 mins ago
Senior Data Platform Engineer
Jobgether
Remote, United States
The ideal candidate is a hands-on data infrastructure engineer who has owned production systems end to end and can combine strong engineering fundamentals with a practical understanding of…
Added 36 mins ago
Quality and Reliability Engineer
Custom Mechanical Solutions
Remote, United States
CMS is looking for a Quality & Reliability Engineer to own and continuously improve the field-to-factory quality feedback loop for custom commercial and industrial HVAC equipment. You will…

Biohub

Senior Staff Data Engineer

NY, United States
Redwood City, CA, United States

$270,000 to $300,000 USD / year

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Job details

Pay: $270,000 to $300,000 USD / year
Experience: 12+ years of experience building reliable, operable data systems at petabyte scale
Posting language: English
Posted: Nov 2, 2026

Original job description

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.

The Team

Biohub is a 501(c)(3) biomedical research organization building the first large-scale scientific initiative combining frontier AI with frontier biology to solve disease. We build the technology to help scientists around the world use AI-powered biology to study how cells operate, organize, and work as part of systems to understand why disease happens and how to correct it. With our compute capacity, AI research and engineering, and state-of-the-art technology for measuring, imaging, and programming biology, we are enabling scientists worldwide to use AI-powered biology to advance our understanding of human health.

The Opportunity

The role is part of the Data Engineering team, which focuses on owning the strategy, sourcing and implementation for data supporting AI research and development. Our goal is to maximize the speed, agility, and capability of biological AI research by connecting public data resources and Biohub's experimental platforms to AI systems. The data that trains biological frontier models comes in dozens of modalities (sequences, images, spatial coordinates, time series, molecular structures, metadata, publication artifacts) each with its own noise characteristics, biases, and information content. The question of how to represent this data for learning is one of the most important open problems in biological AI.

As a Senior Staff Data Engineer at Biohub, you'll be designing systems that ingest data from public repositories, transform heterogeneous biological formats into AI-ready datasets, combine that with proprietary datasets, and deliver training datasets to researchers pushing the boundaries of what's possible in biological AI. The infrastructure you build will directly shape what our models can learn.

We're a small team with significant resources and long time horizons. We use AI tools aggressively in our own work - Claude Code, agents for workflow automation, LLMs for metadata extraction. We care about code quality, operational reliability, and building systems that scale. And we care about the biology: we want engineers who can recognize when a pipeline output is technically correct but scientifically wrong.

If you want to work at the intersection of large-scale infrastructure and frontier science, with real autonomy and the chance to build something genuinely new, we'd like to talk.

What You'll Do

Design and build data pipelines that process genomic and imaging data at petabyte scale
Solve performance and bandwidth challenges with creative engineering
Build agent-based systems for automated dataset curation, quality control, and workflow generation
Create tooling for data cataloging and registration that makes datasets discoverable and accessible
Collaborate with AI Research teams to translate model requirements into data specifications, and with our scientists to integrate public and internal data into large-scale ai-ready datasets
Improve pipeline reliability and observability, working toward 99%+ success rates without manual intervention

What You'll Bring

12+ years of experience building reliable, operable data systems at petabyte scale
Strong software engineering fundamentals
Experience deploying distributed computing frameworks like Databricks, Spark, or Ray for large-scale data processing
Experience building and deploying large scale data platform solutions using infrastructure as code like Terraform or CDK
Experience with cloud infrastructure (AWS preferred) and on prem infrastructure
Comfort with ambiguity; ability to make progress when requirements are evolving
Interest in AI-native development practices and tooling
Nice to have: Background in computational biology, bioinformatics, or life sciences and experience with genomics datasets and formats (FASTQ, BAM, VCF) or imaging formats (OME-Zarr, HDF5)

Compensation

The anticipated base pay ranges for this role in Redwood City, CA and New York City, NY is $270,000–$300,000 annually for the Senior Staff level. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process. This position may be eligible to participate in Biohub's discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with Biohub's total rewards philosophy and may vary by role.

Better Together

As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager's discretion and communicated during the interview process.

Benefits for the Whole You

We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.

Provides a generous employer match on employee 401(k) contributions to support planning for the future.
Paid time off to volunteer at an organization of your choice.
Funding for select family-forming benefits.
Relocation support for employees who need assistance moving

If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.

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