Jobs in the United States

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Added 4 mins ago
FV
Adjunct Instructor - Biomedical Electronics
Fox Valley Technical College (FVTC)
Appleton, WI
- $45 USD / hour
Added 16 mins ago
AW
Technical Program Manager III - AMZ27045.1
Amazon Web Services, Inc.
Seattle, WA
- $148,700 to $201,200 USD / year
Coordinate and manage technical project and program development of large-scale, distributed software applications, systems, platforms, services, or technologies using Object Oriented coding…
Added 16 mins ago
AS
Technical Program Manager III - AMZ26509.1
Amazon.com Services LLC
Arlington, VA
- $154,785 to $201,200 USD / year
Coordinate and manage technical project and program development of large-scale, distributed software applications, systems, platforms, services, or technologies using Object Oriented coding…
Added 16 mins ago
AD
Software Dev Engineer II - AMZ27373.1
Amazon Development Center U.S., Inc.
Boston, MA
- $143,700 to $194,400 USD / year
Position: Software Dev Engineer II - AMZ27373.1
Added 16 mins ago
Software Dev Engineer III - AMZ26892.1
Amazon.com Services LLC
Miami, FL
…three years of experience in the job offered, or as a Software Engineer, Software Developer, or a related occupation. Employer will accept a Bachelor's degree or foreign equivalent in…
Added 16 mins ago
AD
Software Dev Engineer II - AMZ26511.2
Amazon Development Center U.S., Inc.
Santa Clara, CA
- $165,200 to $223,600 USD / year
Position: Software Dev Engineer II - AMZ26511.2
Added 16 mins ago
AW
Software Dev Engineer II - AMZ26548.2
Amazon Web Services, Inc.
Cupertino, CA
- $165,200 to $223,600 USD / year
Position: Software Dev Engineer II - AMZ26548.2
Added 16 mins ago
AD
Enterprise Act Engineer II - AMZ27758.1
Amazon Development Center U.S., Inc.
Mountain View, CA
- $152,797 to $204,300 USD / year
…and one year of experience in the job offered or as a Support Engineer, Systems Engineer, or related occupation. Must have one year of experience in the following skill(s): designing,…
Added 26 mins ago
Sentinel - Staff Systems Engineer - 17379
CORP-Corporate Office
United States
Northrop Grumman Defense Systems is seeking a Staff Systems Engineer (level 5) to join its team. This position is in Roy, Utah and will support the Sentinel program. Northrop Grumman…
Added 26 mins ago
Sentinel - Staff Systems Engineer - Mechanical Systems Design Integrator
CORP-Corporate Office
United States
The Staff Mechanical Systems Design Integrator (level 5 engineer) will work with our Sentinel Systems Engineering & Integration (SE&I) Business Unit’s System Integration & Sustainment (SIS)…
Added 26 mins ago
Staff Systems Engineer - Modeling Simulation & Analysis - 20144
CORP-Corporate Office
United States
Northrop Grumman Defense Systems is seeking a Staff Systems Engineer - Modeling, Simulation & Analysis (level 5) to join its team. This position is in Huntsville, AL.
Added 26 mins ago
Optomechanical Engineer - 2
SP - Launch Vehicles
United States
Northrop Grumman Space Systems is looking for a Optomechanical Engineer - 2 to support the Electro-Optics Group within the Launch Vehicles business unit in Chandler, Arizona.
Added 26 mins ago
Principal Optomechanical Engineer - 3
SP - Launch Vehicles
United States
Northrop Grumman Space Systems is looking for a Principal Optomechanical Engineer - 3 to support the Electro-Optics Group within the Launch Vehicles business unit in Chandler, Arizona.
Added 28 mins ago
Mechanical Engineer II
NUCOR COLD FINISH WISCONSIN INC
JACKSON, WI
Added 28 mins ago
Supplier Quality Engineer I
ROCKLINE INDUSTRIES INC
SHEBOYGAN, WI
Added 28 mins ago
Senior Configuration Management
ULINE INC
PLEASANT PRAIRIE, WI
JOB REQUIREMENTS: Senior Configuration Management Engineer Corporate Headquarters 12575 Uline Drive, Pleasant Prairie, WI 53158 Are you passionate about maintaining the backbone of…
Added 28 mins ago
Applied AI Engineer
AMCOR FLEXIBLES NORTH AMERICA INC
NEENAH, WI
Added 28 mins ago
Engineering Technician
GUHRING INC
BROOKFIELD, WI
Added 28 mins ago
Engineering Technician
GUHRING INC
BROOKFIELD, WI
Added 28 mins ago
Systems Engineer II
WIN, LLC
EAU CLAIRE, WI
Added 28 mins ago
Automotive Quality Engineer
LIPPERT AUTOMOTIVE
EAU CLAIRE, WI
…and premium products to all our customers. Automotive Quality Engineer Our Quality Engineers will establish controls for automotive accessories with development, application and maintenance…
Added 29 mins ago
Analytics Engineer III
GENERAC POWER SYSTEMS
WAUKESHA, WI
Added 29 mins ago
Quality Engineer
DUCOMMUN LABARGE INC
APPLETON, WI
Added 29 mins ago
Sr. Staff Software Engineer, Cribl Dete
CRIBL INC
MADISON, WI
Added 29 mins ago
Principal Engineer, SCADA Engineering (B
INVENERGY LLC
MADISON, WI

Closed listing

Axiom

Software Engineer, Platform Infrastructure

South San Francisco, CA, United States

This opening has closed.

The original listing is kept below for reference.

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Job details

Posting language: English
Posted: Nov 1, 2026

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Original job description

Archived listing. The details below describe a past opening.

Description:

Build the secure, reliable platform that powers Axiom’s scientific AI agents, experimental data pipelines, and products used by the largest pharmaceutical companies and AI labs in the world.

About Axiom:

Axiom’s mission is to eliminate unexpected drug toxicity and unlock an abundance of ultra safe medicines. We are starting with the liver, where toxicity remains a leading cause of drug failure. Our high-throughput human liver safety platform combines advanced human cell systems with imaging, transcriptomics, mass spectrometry, and drug metabolism measurements. Our AI agents integrate these data with chemical structure, human exposure, and thousands of clinical reference compounds to predict whether a drug will be toxic in humans, why, and how to make it safer.

We work with seven of the world’s top twenty pharmaceutical companies to design safety into molecules from the earliest stages. This applied work feeds directly into our partnerships with leading frontier AI labs, turning real discovery challenges and experimental feedback loops into scientific skill trees and reinforcement learning environments that train increasingly superhuman scientists. We then deploy these frontier models to make cancer therapies safer, unlock treatments for chronic diseases that demand exceptional safety, revive promising drugs abandoned because of toxicity, and much more.

Our ultimate ambition is to build a superhuman AI agent that predicts how a drug will behave across all major human organ systems before the first patient receives it. With insanely accurate safety predictions, we aim to enable rapid, high-throughput testing of novel drugs in humans with zero risk of toxicity. This is the key to unlocking an abundance of ultra safe, effective medicines.

What you will do:

Build and operate the shared infrastructure behind Axiom’s scientific data pipelines, AI agents, research workflows, and Translate product.
Own cloud infrastructure, compute, storage, databases, and networking, making systems reliable, secure, scalable, and cost-efficient.
Develop workflow orchestration that lets scientists, engineers, and agents run complex computational pipelines with clear dependencies, durable state, and recovery from failures.
Build secure execution environments for agents, with controlled access to scientific tools, models, and data, strict customer isolation, and resource and budget limits.
Make scientific results reproducible through data versioning, lineage, snapshots, and automated checks that catch stale inputs, inconsistent features, and incomplete outputs.
Build fast development environments, CI, and deployment systems that let people and agents ship changes confidently across development, staging, and production.
Own authentication, permissions, secrets, and workload identity across internal systems, customer workspaces, laboratory partners, and model providers.
Make systems observable through logs, metrics, traces, execution histories, and alerts that help people and agents investigate failures and verify results.
Manage database migrations, backups, and recovery, and resolve production issues across Axiom’s platform and infrastructure providers.
Work directly with scientists, ML researchers, and product engineers to remove operational bottlenecks and turn recurring manual work into reliable, self-service tools.

What we look for:

Exceptional software engineering ability and experience building reliable production systems, with depth in infrastructure, distributed systems, platform engineering, or developer tools.
Strong systems judgment. You simplify complex problems, choose clear abstractions, and build systems that remain understandable as they grow.
End-to-end ownership. You identify what matters, make progress without a detailed specification, and follow through from design to deployment and operation.
An instinct for reliability and correctness. You anticipate failure modes, make failures visible, and prevent silent errors from reaching scientific results or customers.
Strong security judgment. You understand permissions, credentials, isolation, and trust boundaries, and make secure workflows easy to use.
A talent for debugging across application code, databases, networks, cloud services, and execution environments.
Experience building with AI agents and a drive to make them effective users of infrastructure, tools, and data, with appropriate controls and verification.
Care for developer and scientist productivity. You notice recurring friction and replace manual work with dependable tools and automation.
Clear communication, intellectual curiosity, and the willingness to learn biology, chemistry, and ML to build better systems for scientific discovery.

Technical skills we value:

Python, SQL, asynchronous programming, APIs, and production backend systems.
AWS, Modal, Docker, Terraform, cloud networking, and infrastructure as code.
DuckDB/MotherDuck, Postgres, S3, Parquet, database migrations, backups, and recovery.
Workflow orchestration, dependency management, distributed execution, checkpointing, retries, and durable state.
Data versioning, lineage, reproducible pipelines, and automated consistency checks.
IAM, SSO, OAuth/OIDC, workload identity, secrets management, and customer isolation.
Agent execution environments, sandboxing, tool access, model APIs, and resource and budget controls.
CI/CD, GitHub Actions, isolated development environments, automated testing, and deployment strategies.
Observability, including structured logs, metrics, tracing, alerting, Datadog, and production debugging.
TypeScript, SvelteKit, Vercel, and internal developer tools are a plus.

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