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Senior Build Reliability Engineer, Hardware
Varda Space Industries
El Segundo, CA
Low Earth orbit is open for business. Varda is accelerating the development of commercial space infrastructure, from in-orbit pharmaceutical processing to reliable and economical reentry…
Added 9 mins ago
Systems Engineer / Principal Systems Engineer (AHT)
Northrop Grumman
Manhattan Beach, CA
Northrop Grumman Defense Systems sector (NGDS) is seeking a Systems Engineer or Principal Systems Engineer to join our growing team of diverse professionals. The candidate will support…
Added 9 mins ago
Principal Systems Engineer (Top Secret Clearance)
Northrop Grumman
Manhattan Beach, CA
Northrop Grumman Defense Systems sector (NGDS) is seeking a Principal Systems Engineer to join our growing team of diverse professionals. The candidate will support Agile development of MS…
Added 10 mins ago
Staff Mechanical Engineer
Empirical Systems Aerospace, Inc.
San Luis Obispo, CA
The Staff Mechanical Engineer will play a key role in the design, development, and validation of mechanical components and systems for new aircraft programs. This position supports…
Added 10 mins ago
Systems Design Engineer - Bioengineering
ThermoFisher Scientific
Pleasanton, CA
Support System Definition and Product Development
Added 10 mins ago
Staff Systems Design Engineer - Consumables / Microfluidics
ThermoFisher Scientific
Pleasanton, CA
We are seeking a Staff Engineer in Consumables & Microfluidics to lead the design and commercialization of next-generation consumables for molecular biology, genetic-analysis and…
Added 10 mins ago
Sr. Applications Engineer - FIB/PFIB
ThermoFisher Scientific
Fremont, CA
Join our team at Thermo Fisher Scientific as a Senior Field Applications Engineer, where you'll provide technical expertise to semiconductor and life sciences companies. Working at the…
Added 10 mins ago
AE
Campus Undergraduate Full-Time Engineer - 2027 AI Engineer I, Enterprise Technology Services- Palo Alto, CA
American Express
Palo Alto, CA
- $78,000 to $124,750 USD / year
- Full-time
…high-quality experience for customers and colleagues. We also provide product management for core enterprise platforms, and lead technology risk and information security, enterprise data…
Added 10 mins ago
AE
Campus Graduate Masters Full-Time Engineer - 2027 AI Engineer I, Enterprise Technology Services- Palo Alto, CA
American Express
Palo Alto, CA
- $78,000 to $124,750 USD / year
- Full-time
…high-quality experience for customers and colleagues. We also provide product management for core enterprise platforms, and lead technology risk and information security, enterprise data…
Added 10 mins ago
Hardware Engineer I (Intern) - United States
Cisco
San Jose, CA · Carlsbad, CA
…ideas to push boundaries and help each other grow. Because full product development - from design to qualification to production - is within our team, we’re able to think differently,…
Added 10 mins ago
C
Technical Marketing Engineer I (Full Time) - United States
Cisco
San Jose, CA · Milpitas, CA
- Full-time
…products. You will work closely with experienced mentors in Product Management, UX, and Sales, gaining exposure to the full product lifecycle while helping to solve real-world customer…
Added 10 mins ago
Signals for FSI - Product Forward Deployed Engineer - Innovation_Delivery_Transformation
Deloitte
Costa Mesa, CA · San Diego, CA · Sacramento, CA · San Francisco, CA · San Jose, CA
Are you energized by both winning the deal and delivering on it? As a Product Forward Deployed Engineer (pFDE), you'll be the GTM & Delivery engine for Signals, a priority product in the…
Added 10 mins ago
Lead Product Forward Deployed Engineer (pFDE) - Products & Platforms
Deloitte
San Diego, CA · San Jose, CA · San Francisco, CA · Costa Mesa, CA · Sacramento, CA
We are looking for a highly skilled and client-facing Forward Deployed Engineer (FDE) to sit at the intersection of engineering excellence and customer partnership. In this role, you will…
Added 10 mins ago
Lead UI Engineer - Products & Platforms
Deloitte
San Diego, CA · Sacramento, CA · San Jose, CA · San Francisco, CA · Costa Mesa, CA
The BankingSuite team is looking is looking for a Lead UI Engineer with a passion for innovation and the experience to launch a high-quality digital banking product as part of a FinTech…
Added 10 mins ago
Banking Product Forward Deployed Engineer - Products & Platforms
Deloitte
Costa Mesa, CA · San Francisco, CA · San Diego, CA · Sacramento, CA · San Jose, CA
We are looking for a highly skilled and client-facing Forward Deployed Engineer (FDE) to sit at the intersection of engineering excellence and customer partnership. In this role, you will…
Added 10 mins ago
ConvergeProsperity - Product Forward Deployed Engineer, BankingSuite (Manager) - Products & Platforms
Deloitte
San Diego, CA · Costa Mesa, CA · Sacramento, CA · San Francisco, CA · San Jose, CA · Los Angeles, CA
We are looking for a highly skilled and client-facing Forward Deployed Engineer (FDE) to sit at the intersection of engineering excellence and customer partnership. In this role, you will…
Added 10 mins ago
ConvergeCONSUMER - Technical Software Engineering Lead (Manager) - Products & Platforms
Deloitte
Sacramento, CA · San Diego, CA · San Francisco, CA · Costa Mesa, CA · San Jose, CA · Los Angeles, CA
Are you an experienced Software Engineer who has led the development of world-class software or digital products? Are you looking for an opportunity to expand your scope and lead products…
Added 11 mins ago
Life Sciences Experience Design Strategy Manager
Deloitte
San Diego, CA · Sacramento, CA · Costa Mesa, CA · San Francisco, CA · San Jose, CA · Los Angeles, CA
Understand which AI-enabled tools and modern ways of working can accelerate research synthesis, concept development, and product planning and champion usage.
Added 11 mins ago
ConvergeProsperity - Lead Product Forward Deployed Engineer for FSI Signals - Products & Platforms
Deloitte
San Diego, CA · San Francisco, CA · Sacramento, CA · Los Angeles, CA · San Jose, CA · Costa Mesa, CA
Are you energized by both winning the deal and delivering on it? As a Product Forward Deployed Engineer (pFDE), you'll be the GTM & Delivery engine for Signals, a priority product in the…
Added 11 mins ago
Software Engineer III - Full-stack Developer with Anthropic Experience
Deloitte
Costa Mesa, CA · San Francisco, CA · Sacramento, CA · San Jose, CA · Los Angeles, CA · San Diego, CA
Software Engineer III with Agentic AI Experience, AI & Engineering/Engineering as a Service
Added 11 mins ago
Consultant Chief Engineer (AHT)
Northrop Grumman
Los Angeles, CA
…future of Air Warfare Systems and drive excellence in missile development as a Consulting Chief Engineer . As part of NGDS, you’ll collaborate with top leaders to bring game-changing…
Added 11 mins ago
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Software Engineer, Specs Lenses C++, Level 5
Snap Inc.
Los Angeles, CA · San Francisco, CA · Palo Alto, CA
- $178,000 to $313,000 USD / year
We’re looking for a Software Engineer to join Lens Studio at Snap Inc!
Added 43 mins ago
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Lead Principal Platform Software Engineer
Oracle
United States
- $113,600 to $306,400 USD / year
Building off our Cloud momentum, Oracle has formed a new organization - Oracle Health & AI. This team will focus on product development and product strategy for Oracle Health, while…
Added 51 mins ago
Business Intelligence Engineer - SCOT, Fulfillment Optimization, SCOT-FO LRN
Amazon
Bellevue, WA
The FO Planning & Forecasting team is seeking a Business Intelligence Engineer (BIE) who combines deep analytical skills with a builder's mindset - someone who can architect data pipelines,…
Added 51 mins ago
Software Dev Engineer II, AFT Outbound & Flow
Amazon
Bellevue, WA
Are you ready for a challenge? As a Software Development Engineer in the 'Fulfillment Execution Services' team, you will get the opportunity to develop our next generation of foundational…

Axiom

Software Engineer, Platform Infrastructure

South San Francisco, CA, United States

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Job details

Posting language: English
Posted: Nov 1, 2026

Original job description

Description:

Build the secure, reliable platform that powers Axiom’s scientific AI agents, experimental data pipelines, and products used by the largest pharmaceutical companies and AI labs in the world.

About Axiom:

Axiom’s mission is to eliminate unexpected drug toxicity and unlock an abundance of ultra safe medicines. We are starting with the liver, where toxicity remains a leading cause of drug failure. Our high-throughput human liver safety platform combines advanced human cell systems with imaging, transcriptomics, mass spectrometry, and drug metabolism measurements. Our AI agents integrate these data with chemical structure, human exposure, and thousands of clinical reference compounds to predict whether a drug will be toxic in humans, why, and how to make it safer.

We work with seven of the world’s top twenty pharmaceutical companies to design safety into molecules from the earliest stages. This applied work feeds directly into our partnerships with leading frontier AI labs, turning real discovery challenges and experimental feedback loops into scientific skill trees and reinforcement learning environments that train increasingly superhuman scientists. We then deploy these frontier models to make cancer therapies safer, unlock treatments for chronic diseases that demand exceptional safety, revive promising drugs abandoned because of toxicity, and much more.

Our ultimate ambition is to build a superhuman AI agent that predicts how a drug will behave across all major human organ systems before the first patient receives it. With insanely accurate safety predictions, we aim to enable rapid, high-throughput testing of novel drugs in humans with zero risk of toxicity. This is the key to unlocking an abundance of ultra safe, effective medicines.

What you will do:

Build and operate the shared infrastructure behind Axiom’s scientific data pipelines, AI agents, research workflows, and Translate product.
Own cloud infrastructure, compute, storage, databases, and networking, making systems reliable, secure, scalable, and cost-efficient.
Develop workflow orchestration that lets scientists, engineers, and agents run complex computational pipelines with clear dependencies, durable state, and recovery from failures.
Build secure execution environments for agents, with controlled access to scientific tools, models, and data, strict customer isolation, and resource and budget limits.
Make scientific results reproducible through data versioning, lineage, snapshots, and automated checks that catch stale inputs, inconsistent features, and incomplete outputs.
Build fast development environments, CI, and deployment systems that let people and agents ship changes confidently across development, staging, and production.
Own authentication, permissions, secrets, and workload identity across internal systems, customer workspaces, laboratory partners, and model providers.
Make systems observable through logs, metrics, traces, execution histories, and alerts that help people and agents investigate failures and verify results.
Manage database migrations, backups, and recovery, and resolve production issues across Axiom’s platform and infrastructure providers.
Work directly with scientists, ML researchers, and product engineers to remove operational bottlenecks and turn recurring manual work into reliable, self-service tools.

What we look for:

Exceptional software engineering ability and experience building reliable production systems, with depth in infrastructure, distributed systems, platform engineering, or developer tools.
Strong systems judgment. You simplify complex problems, choose clear abstractions, and build systems that remain understandable as they grow.
End-to-end ownership. You identify what matters, make progress without a detailed specification, and follow through from design to deployment and operation.
An instinct for reliability and correctness. You anticipate failure modes, make failures visible, and prevent silent errors from reaching scientific results or customers.
Strong security judgment. You understand permissions, credentials, isolation, and trust boundaries, and make secure workflows easy to use.
A talent for debugging across application code, databases, networks, cloud services, and execution environments.
Experience building with AI agents and a drive to make them effective users of infrastructure, tools, and data, with appropriate controls and verification.
Care for developer and scientist productivity. You notice recurring friction and replace manual work with dependable tools and automation.
Clear communication, intellectual curiosity, and the willingness to learn biology, chemistry, and ML to build better systems for scientific discovery.

Technical skills we value:

Python, SQL, asynchronous programming, APIs, and production backend systems.
AWS, Modal, Docker, Terraform, cloud networking, and infrastructure as code.
DuckDB/MotherDuck, Postgres, S3, Parquet, database migrations, backups, and recovery.
Workflow orchestration, dependency management, distributed execution, checkpointing, retries, and durable state.
Data versioning, lineage, reproducible pipelines, and automated consistency checks.
IAM, SSO, OAuth/OIDC, workload identity, secrets management, and customer isolation.
Agent execution environments, sandboxing, tool access, model APIs, and resource and budget controls.
CI/CD, GitHub Actions, isolated development environments, automated testing, and deployment strategies.
Observability, including structured logs, metrics, tracing, alerting, Datadog, and production debugging.
TypeScript, SvelteKit, Vercel, and internal developer tools are a plus.

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