Jobs in the United States

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Added 1 hour ago
Senior Software Engineer
DomainTools
Remote, United States
DomainTools is hiring a Senior Software Engineer to join our Engineering Team. This role is perfect for a creative problem-solver with deep expertise in large-scale data engineering and a…
Added 1 hour ago
Senior Software Engineer
DomainTools
Remote, United States
DomainTools is hiring a Senior Software Engineer to join our Engineering Team. This role is perfect for a creative problem-solver with deep expertise in large-scale data engineering and a…
Added 1 hour ago
Senior Software Engineer
DomainTools
Remote, United States
DomainTools is hiring a Senior Software Engineer to join our Engineering Team. This role is perfect for a creative problem-solver with deep expertise in large-scale data engineering and a…
Added 1 hour ago
Senior Software Engineer
DomainTools
Remote, United States
DomainTools is hiring a Senior Software Engineer to join our Engineering Team. This role is perfect for a creative problem-solver with deep expertise in large-scale data engineering and a…
Added 2 hours ago
Senior DevOps
KēSTA I.T.
Remote, United States
The work spans the full delivery and operations stack: Azure DevOps YAML pipelines and release process, a Linux (Debian) and Windows server fleet, a private cloud built on Proxmox…
Added 5 hours ago
Senior Developer - Full Stack
Cydcor
Remote, United States
You do not need to be a Salesforce expert. You do need to be the kind of engineer other strong engineers want in the room: someone who picks up unfamiliar systems quickly, reasons about…
Added 6 hours ago
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Principal Software Engineer - Full Stack
CVector - Industrial AI
Remote, United States
- $150,000 to $175,000 USD / year
As a Principal Full Stack Software Engineer, you will own the technical direction of CVector’s customer-facing platform end to end - from the real-time data visualization and AI-driven…
Added 6 hours ago
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Senior Software Engineer - Full Stack
CVector - Industrial AI
Remote, United States
- $125,000 to $150,000 USD / year
As a Senior Full Stack Software Engineer, you will play a key role in designing, building, and evolving CVector’s core platform - including our web applications, back-end data pipelines,…
Added 6 hours ago
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Senior .NET Full Stack Engineer with C#
Cognizant
Trenton, NJ
- $86,000 to $99,000 USD / year
As a Senior .NET Full Stack Engineer with C#, you will make an impact by designing and developing scalable enterprise applications that support healthcare payer operations, including…
Added 6 hours ago
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Senior Full Stack Engineer – .NET & C#
Cognizant
Trenton, NJ
- $86,000 to $99,000 USD / year
As a Senior Full Stack Engineer – .NET & C#, you will make an impact by designing and developing scalable enterprise applications that support healthcare payer operations, including…
Added 6 hours ago
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Senior Java Full Stack Engineer – Spring Boot & AWS
Cognizant
Trenton, NJ
- $86,000 to $99,000 USD / year
As a Senior Java Full Stack Engineer – Spring Boot & AWS , you will make an impact by designing and delivering scalable, secure, cloud-based applications using Java, Spring Boot, React, and…
Added 9 hours ago
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Senior Full Stack Ruby on Rails Engineer
SmartFinancial
Remote, United States
- $150,000 to $170,000 USD / year
We’re seeking an experienced Senior Full Stack Ruby on Rails Engineer to help build, evolve, and scale the core systems that power our agent-facing, carrier-facing, and internal…
Added 9 hours ago
C|
Senior Software Engineer III, Backend
Connexity | Skimlinks, a Taboola company
Remote, United States
- $175,000 to $200,000 USD / year
We are seeking a skilled and motivated Senior Software Engineer III, Backend to join our Internal Tools team. Our team owns the design and implementation of our next-generation internal…
Added 15 hours ago
SA
Engineer II, Software - Ground Control Station - Full Stack - New Grad - 6140
Shield AI
Washington, DC
- $77,200 to $211,200 USD / year
…post-mission debrief for operators of unmanned systems. Our full-stack engineers build web-based operator experiences and supporting services that bring program and platform capabilities…
Added 15 hours ago
OS
Senior Software Engineer
Odyssey Systems Cons
Colorado Springs, CO
- $31,533 USD / year
We are seeking a Senior Software Engineer to be a primary technical contributor on the Multimode Threat Engagement Simulation Platform. You will own significant portions of the stack…
Added 15 hours ago
TT
Senior Full-Stack Engineer
True Talent Solutions Partners
Remote, United States
- $200,000 to $275,000 USD / year
Join a small engineering team building a marketplace for GPU compute. This senior, backend-focused role combines architecture, hands-on development, and product collaboration to deliver…
Added 17 hours ago
Senior Frontend Software Engineer
Raydar
New York, NY
…the design, speed and quality of user-facing interfaces for a web app and website, working with a small engineering group on client-side architecture. The role calls for deep frontend…
Added 17 hours ago
Software Engineer 3
Kiewit
Lenexa, KS
TAG is hiring Software Engineer to help design and deliver AI-powered enterprise applications across Kiewit’s district portfolio. This role is ideal for a developer who has outgrown pure…
Added 21 hours ago
PG
Senior AI Engineer
Premier Global Links
San Francisco · San Francisco, CA
- $180,000 to $275,000 USD / year
This role is ideal for an AI Engineer or Full-Stack Engineer with hands-on experience building and deploying customer-facing agentic AI applications. You will design, develop, and own AI…
Added 23 hours ago
Staff Software Engineer, Foundations
Atria Health and Research Institute
Remote, United States
Strong full-stack skills: you can design an API and data model, build the UI that consumes it, and wire up monitoring and metrics.
Added 23 hours ago
Staff Software Engineer, Foundations
Atria Health and Research Institute
Remote, United States
Strong full-stack skills: you can design an API and data model, build the UI that consumes it, and wire up monitoring and metrics.
Added 1 day ago
A&
Appian Developer
Astor & Sanders
Remote, United States
- $130,000 to $150,000 USD / year
Must have bachelor's degree with five (5) plus years (with a minimum of 3 years of experience in Appian) of hands-on full stack experience developing solutions using agile/SAFe…
Added 1 day ago
Senior .Net Software Engineer
Aristotle
Remote, United States
As a Senior .Net Software Engineer for PredictIt you will get to work on challenging and rewarding projects across the tech stack: from creating innovative web experiences to redesigning…
Added 1 day ago
Senior Java Developer
Toyota
Plano, TX
Toyota Financial Services Enterprise Platforms team is seeking a highly motivated Senior Software Engineer to help our growing Enterprise platform needs. The Senior Java Developer will…
Added 1 day ago
V
Senior QA/SDET
Vouched
Remote, United States
- $180,000 to $210,000 USD / year
You will own quality across the full product lifecycle, from reviewing requirements and designs through test planning, automation, release validation, and production verification. You will…

Axella

Senior / Staff Software Engineer

Boston, MA, United States

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Job details

Posting language: English

Original job description

Why this role matters Biomanufacturing is one of the most complex and failure-prone systems in the world. Every year, billions of dollars and critical therapies are delayed or lost - not because the science fails, but because process understanding and manufacturing execution break down somewhere along the way. It’s a systems problem more than a software or biology problem, and we’re building the AI platform to solve it. What we’re building Axella Biosciences is a stealth mode company developing an AI-driven CMC and biomanufacturing execution platform that designs manufacturing processes in silico, reduces deviations and failures during development and GMP production, and helps diagnose and resolve issues in real time. We’re already in production with early customers, and now we’re scaling into regulated environments (GxP, 21 CFR Part 11), across more of the biomanufacturing lifecycle, and toward autonomous, agent-driven execution. We’re backed by top VCs such as General Catalyst, Sequoia, and Hitachi Ventures, among others. The role We’re hiring a foundational technical leader to own engineering execution end-to-end - architecture, AI systems design, infrastructure, and the engineering standards and culture we build from here. You’ll work closely with domain experts across biomanufacturing and AI. What you’ll work on AI systems and agents. You’ll build and deploy agentic systems based on frontier models (Claude, Open AI) for real manufacturing workflows, design tool-augmented agents using MCP and structured data access, improve our RAG systems (retrieval quality, grounding, citations, reasoning), and develop evaluation frameworks - gold sets, regression testing, live metrics. Core platform. Full-stack development across React, Node.js, and MongoDB. Building document intelligence pipelines for batch records, PDFs, Excel files, and images, and turning unstructured manufacturing data into structured, usable knowledge. Infrastructure and scale. Evolving our AWS architecture from early-stage to production-grade, implementing observability, reliability, and CI/CD, and designing systems that hold up in regulated environments (GxP, Part 11, SOC 2). Customer deployment. Getting systems into real manufacturing environments, integrating with LIMS, ERP, and QMS, and working directly with customers and partners to validate how these systems perform in the wild. What we’re looking for The core: 7+ years of software engineering experience with a proven track record of delivering production systems end-to-end in startup environments - including problem scoping, requirements gathering, product planning, architecture, modern web backend and frontend development, infrastructure, and maintenance. You're comfortable identifying which problems are worth solving, not just executing on well-defined ones, and you can drive technical direction independently in ambiguous environments. Candidates must have strong production experience owning LLM-powered systems (RAG, agents, tool use) - including the reliability, evaluation, and iteration strategy that keeps them working as they scale. You should be comfortable operating production systems in cloud environments. Experience with infrastructure as code tools such as Terraform is a plus, as is experience with AWS, Typescript, React, Node.js and GitHub Actions. We're looking for a bar raiser who works independently and can build cross-functional alignment around the technical practices that matter - things like code coverage, evaluation infrastructure, and observability - and drive them to adoption without heavy process. Things that stand out: experience with agent frameworks or MCP-style architectures, building evaluation systems for LLM reliability, document parsing and structured extraction pipelines, work in regulated or high-reliability environments, and any exposure to biotech, pharma, or complex industrial systems. What makes this role unique The work has real-world impact - your systems shape how drugs are manufactured. The problems are genuinely hard: reasoning over messy, high-stakes data in regulated environments. You’ll have high autonomy and own major technical decisions, and as a foundational hire, the engineering culture and architecture will reflect the choices you make. The system also gets better with every deployment, which is a fun place to be.

Compensation

Competitive salary plus meaningful early-stage equity.

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Skills

Full-stack development
React
Node.js
MongoDB
Microsoft Excel
AWS
CI/CD
LIMS
ERP
Wheel impact load detector
Requirements gathering
Front-end development
Infrastructure as code
IBM Terraform
GitHub
Grading systems

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