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Added 1 min ago
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Senior Process Engineer, Cell Therapy Process Development
AstraZeneca Pharmaceuticals LP Company
Gaithersburg, MD
- $96,000 to $144,000 USD / year
We are seeking a highly motivated Senior Process Engineer to support cell therapy process characterization and commercialization activities. In this role, you will play critical role in…
Added 1 min ago
Senior Estimating Engineer, Heavy Equipment Solutions
J.E. Dunn Construction Group Inc P
Kansas City, MO
The Senior Estimating Engineer will continue learning JE Dunn processes and tools and developing professional skills while assisting with the preparation of more complex cost estimates for…
Added 3 mins ago
Head of Software Architecture
Power Factors
Houston, TX · Boston, MA · Burlington, VT
Mentor senior engineers and engineering leaders on architectural judgment, system design, and technical tradeoff analysis
Added 3 mins ago
Sr. Specialist, Systems Engineer (Environmental Qualification)
Acron Aviation
Phoenix, AZ · Grand Rapids, MI
Acron Aviation is seeking a Senior Specialist, Systems Engineer for our Environmental Qualifications to provide technical leadership for the planning, coordination, execution, and closure…
Added 3 mins ago
Senior Reliability Engineer
AVE Medtronic Vascular Inc
Mounds View, MN
This position will be based at our Mounds View, MN facility which requires a minimum of 4 days per week on-site for in-person collaboration
Added 5 mins ago
Senior Controls and Automation Engineer
Patterson-UTI Drilling Company LLC
Houston, TX
The Senior Controls and Automation Engineer will be responsible for the conception, design, development, implementation, and maintenance of drilling rig control system software and…
Added 5 mins ago
Mechanical Design Engineer II
Industrial Electric Manufacturing
Fremont, CA
The Mechanical Design Engineer II supports the design-to-order (DTO) engineering process for IEM’s low voltage power distribution products. This role involves extensive 3D modeling and 2D…
Added 6 mins ago
Senior Project Engineer, NA
Vantage Data Centers Management Company LLC
Shackelford County, TX
The Senior Project Engineer of Construction can manage multiple project scopes within a project. The senior project engineer will also drive core project coordination across several teams…
Added 6 mins ago
GD
Senior Principal Software Systems Engineer
General Dynamics Mis
Boulder, CO
- $183,381 to $193,409 USD / year
As a Senior Principal Software Systems Engineer, you will provide architectural recommendations and design inputs to a cross functional team that develops complex software systems that…
Added 6 mins ago
Q
Lead Electrical Engineer - 1116
Quantinuum
Broomfield, CO
- $164,000 to $185,000 USD / year
We are seeking a Lead Electrical Engineer in our Broomfield, CO location. In this role, you will lead a team to develop and deliver large-scale electrical systems that control our…
Added 6 mins ago
Staff Network Engineer
Stoughton, MA · Broomfield, CO
…segment, every connection counts. With roughly 700 employees, we design, deploy, and operate the mission-critical communications infrastructure that public safety agencies and emergency…
Added 6 mins ago
Engineer Lead Senior
The Elevance Health Companies, Inc.
United States
The Engineer Lead Senior is responsible for leading the end to end application system development and maintenance on large complex enterprise wide technology platforms.
Added 7 mins ago
Senior Software Engineer, Agent Oversight
Scale AI
San Francisco, CA · NY
…Agentic AI in production, paired with applied ML research, design, and evaluation to ensure these systems perform reliably at the scale our customers demand. We’re growing fast, with…
Added 7 mins ago
Engineer-Licensed Professional/Design- 075934
Wayne County
Detroit, MI
The Engineer-Licensed Professional - Design is assigned to the Design Office of the Engineering Division. This position assists the Senior Licensed Professional Engineer / Design in…
Added 7 mins ago
Engineer III or Senior Engineer (Electrical)
Duke Energy
Seneca, SC
Senior Nuclear Engineer is the career/senior level of the Engineering classification hierarchy. Employees at this level manage work in engineering areas of electrical systems and components…
Added 7 mins ago
Engineer III or Senior Engineer
Duke Energy
Seneca, SC
However, hybrid employees must live within a reasonable commute to their design
Added 7 mins ago
Network Engineer - Principal
Amentum
Warrenton, VA
Must have active Top-Secret clearance with SCI or the ability to acquire Top Secret/SCI
Added 7 mins ago
Senior Network Engineer
Amentum
Fort Meade, MD
Security Clearance Required: Must have active Top Secret clearance with SCI eligibility
Added 7 mins ago
Engineer 1
M. C. Dean
Rock Hill, SC
The Engineer provides system programming and management support for large scale networking infrastructures. The responsibilities include the administration and maintenance of high…
Added 8 mins ago
Senior Electrical Engineering Leader - Power Infrastructure
GE Vernova
Greenville, SC
We are seeking a Senior Electrical Engineering Leader - Power Infrastructure to serve as the senior technical authority for electrical infrastructure across our world-class test facilities.…
Added 8 mins ago
Group Leader - Logistics, Transportation, & Packaging Engineer
Bosch Group
Florence, KY
Individual must have ability to multitask and make independent decisions that may be of a complex nature · Must have a high sense of urgency, attention to detail, excellent organizational skills and be able to work effectively in a fast-paced environment
Added 10 mins ago
A
Senior Process Engineer, Cell Therapy Process Development
AstraZeneca
Gaithersburg, MD · Gaithersburg
- $96,000 to $144,000 USD / year
We are seeking a highly motivated Senior Process Engineer to support cell therapy process characterization and commercialization activities. In this role, you will play critical role in…
Added 10 mins ago
O
AI Solutions Engineer, GTM
OpenGov
Chicago, IL
- $150,000 to $165,000 USD / year
OpenGov is seeking an AI Solutions Engineer to serve as a dedicated practitioner within the Applied AI team, focused on Sales/GTM use cases across the revenue organization - SDR outbound,…
Added 10 mins ago
O
Forward Deployer Engineer (Revenue)
OpenGov
Chicago, IL
- $150,000 to $165,000 USD / year
OpenGov is seeking a Forward Deployed Engineer (Revenue) to serve as a dedicated practitioner within the Applied AI team, focused on Sales/GTM use cases across the revenue organization -…
Added 12 mins ago
TL
Senior Engineer, Water
T.Y. Lin International
DC · WA
- $117,600 to $176,400 USD / year
Our TYLin Water Sector is seeking a Senior Engineer (Design) to support a long-term program and work on one of the largest sewer rehabilitation project, the Potomac Interceptor Program for…

AstraZeneca

Senior Process Engineer, Cell Therapy Process Development

Gaithersburg, MD, United States
Gaithersburg, United States

$96,000 to $144,000 USD / year

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Job details

Pay: $96,000 to $144,000 USD / year
Apply by: May 11, 2027
Posting language: English
Posted: Nov 12, 2026

Original job description

Position Summary We are seeking a highly motivated Senior Process Engineer to support cell therapy process characterization and commercialization activities. In this role, you will play critical role in advancing late-stage cell therapy process development, process characterization, PPQ readiness, BLA‑enabling studies, and technology transfer to different manufacturing sites.

This position focuses specifically on cell therapy unit operations, including T-cell enrichment, activation, transduction, washes and harvest either semi-automated or automated equipment. The ideal candidate brings deep technical expertise, hands-on experience with cell therapy unit operations, and demonstrates success in supporting clinical and commercial readiness.

Key Responsibilities

Process development and characterization

Design, execute, and support autologous or allogenic cell therapy process optimization and robustness studies.
Drive implementation of closed-system operations and automation strategies to support scalability and compliance.
Plan and execute process characterization studies (DOE, multivariate studies, scale‑down models, and scale‑up assessments) in alignment with QbD and ICH guidelines.
Perform risk assessment, data analysis, write technical reports, and present outcome of the studies to cross‑functional teams and governance forums.
Support development and refinement of control strategies for cell therapy processes, including raw materials, and cell therapy process parameters.
Conduct batch record review, deviation assessment, and data trending to ensure robustness of cell therapy manufacturing processes.
Apply AI‑enabled tools and digital analytics to accelerate data review, trend analysis, batch record evaluation, and process understanding.

PPQ, Tech Transfer & Manufacturing Readiness

Contribute to PPQ planning, readiness, execution, and documentation for cell therapy processes.
Support technology transfer of cell therapy processes to internal manufacturing sites including make-a-batch assessments and drafting manufacturing batch record.
Provide on‑the‑floor technical support during scale‑up, engineering runs, PPQ batches, and commercial manufacturing campaigns (including off‑shift support when required).
Support raw material risk assessments, comparability studies, and process risk evaluations across facilities and platforms.

Regulatory Support

Contribute to authoring and reviewing CMC documentation, including cell therapy process descriptions, characterization summaries, PPQ protocols and reports, and control strategy elements.
Support preparation of BLA/MAA submissions and responses to regulatory questions related to cell therapy manufacturing.

Cross‑Functional Collaboration

Work closely with analytical sciences, quality, regulatory, and manufacturing teams to ensure end‑to‑end process alignment.
Represent cell therapy characterization activities in technical meetings, reviews, and governance discussions.
Support lifecycle management, post‑approval changes, and continuous improvement initiatives for cell therapy processes.

Required Qualifications

Ph.D. in Chemical Engineering, Biochemical Engineering, Biotechnology, or related field with 2+ years of industry experience; OR M.S. with 5+ years; OR B.S. with 7+ years of hands‑on industry experience.
Strong technical expertise in key cell therapy unit operations (e.g., cell isolation, activation, transduction, expansion, harvest, formulation, cryopreservation).
Demonstrated experience with GMP operations and late‑stage / commercial readiness.
Proven ability to analyze complex datasets, develop sound recommendations, and communicate clearly across levels
Experience with late‑stage development, process characterization, and PPQ principles for cell therapy processes.
Demonstrated proficiency in applying AI tools and digital solutions to data analysis, documentation, and workflow automation.
Experience working in GMP environments, including batch record execution or review, deviations, and investigations.
Strong technical writing, data analysis, and problem‑solving skills.

Preferred Qualifications

Experience with viral vector handling (Lentivirus, AAV) in manufacturing processes.
Familiarity with automation platforms (e.g., CliniMACS Prodigy, Lovo, G-Rex, Wave bioreactors).
Experience implementing closed, automated, or high‑throughput systems.
Experience designing and executing DOE and multivariate data analysis for cell therapy processes.
Experience with JMP or similar statistical analysis tools.
Experience contributing to BLA/MAA submissions or regulatory interactions.
Knowledge of control strategy development and risk assessment tools (e.g., FMEA).
Formal training or demonstrated application of digitalization, automation, or AI‑enabled tools in bioprocess development.

Key Competencies

Strong experimental design and execution skills.
Excellent cross‑functional communication and collaboration.
Ability to operate effectively in fast‑paced, late‑stage development environments.
Scientific curiosity, ownership mindset, and willingness to support manufacturing operations.

The annual base pay for this position ranges from $96K to $144K. Our positions offer eligibility for multiple incentives an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. # Cell Therapy

Date Posted 12-Nov-2026 Closing Date 19-Nov-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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Jobs in the United States