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Added 16 mins ago
LEAD TECHNICAL PROJECT MANAGER-INDIA
Lumen Technologies
HOME, IN
We're looking for a Senior Project Manager to lead strategic initiatives and other key projects from planning through delivery. Many of our current initiatives involve ERP systems, so…
Added 23 mins ago
Learning Consultant, Workforce Development (Clinician Orientation & eStar) - Hybrid in Nashville, TN
Vanderbilt University Medical Center
Nashville, TN
…leverages learning technologies, authoring tools, learning management systems, and virtual collaboration platforms to develop, update, or curate digital learning resources and performance…
Added 27 mins ago
Systems Engineer -787 Airplane Level Integration (Experienced or Senior)
The Boeing Company
North Charleston, SC
…facilitation of Tier 0-2 requirements processes on the 787 program. They lead technical design reviews to ensure quality standards are met for all new, modified and deviated requirements.…
Added 27 mins ago
Associate Systems Engineer -787 Airplane Level Integration
The Boeing Company
North Charleston, SC
…facilitation of Tier 0-2 requirements processes on the 787 program. They lead technical design reviews to ensure quality standards are met for all new, modified and deviated requirements.…
Added 27 mins ago
Production Control Leader (1st Shift)
GE Aerospace
Greenville, SC
Provide direct supervision and people management for hourly production employees, including coaching, performance management, accountability, and daily work direction.
Added 27 mins ago
EC
Application Engineer - Critical Power Projects
Eaton Corporation
Columbia, SC · Greenwood, SC
- $86,000 to $126,000 USD / year
Create proposals for projects • Lead the financial development and approval of cost estimates for proposals with bid team. Bid team can be comprised of project managers, engineering…
Added 38 mins ago
WC
Manager, Real Estate Lending Closing & Post-Closing
Westerra Credit Union
Parker, CO
- $85,871 to $109,485 USD / year
…controls, loan quality, seller and member service, pipeline management and scalable capacity across these functions. The Manager oversees the lifecycle from preparation for closing through…
Added 39 mins ago
Supervisory Civil Engineer
Bureau of Reclamation
Grand Junction, CO
…will perform include but are not limited to the following: Lead the planning, implementation, and oversight of Operation and Maintenance (O&M) and Safety of Dams (SOD) programs for water…
Added 39 mins ago
Operations Leader - Cyber/Test
GE Vernova
Longmont, CO
Project Management Expertise: Ability to plan, document, execute, and deliver multi-disciplinary programs that integrate mechanical, electrical, and digital/IT workflows; lead…
Added 39 mins ago
CIVIL ENGINEER (CONSTRUCTION MANAGEMENT)
Bureau of Reclamation
Lakewood, CO
Summary You will serve as a CIVIL ENGINEER (CONSTRUCTION MANAGEMENT) This position is located within the Department of the Interior, Bureau of Reclamation, Denver, Construction Manamgement…
Added 39 mins ago
Pharmacy Technician Specialist
AdventHealth
Littleton, CO
…practice areas as needed to address staff shortages, support program and service performance, and assure achievement of strategic goals across patient care areas serviced by the pharmacy…
Added 39 mins ago
Charge Nurse (RN) - CVICU
AdventHealth
Littleton, CO
…salary increases of up to 20%* through our Clinical Ladder Program based on experience, professional development, and achievement of advancement…
Added 39 mins ago
2027 Space Systems Architecture Undergrad Intern
The Aerospace Corpor
Colorado Springs, CO
…NNSA, DHS, and others. Interns in ArCon participate in and lead architecture trade studies, architecture conceptualization studies, architecture modeling tasks, and program assessment…
Added 39 mins ago
2027 Space Enterprise Design and Optimization Graduate Intern
The Aerospace Corpor
Colorado Springs, CO
…technical deep dives, trade studies, and assessments to satisfy project objectives and tasks. Work Model This is a full-time position based in El Segundo, CA; Chantilly, VA; or Colorado…
Added 39 mins ago
2027 Space Enterprise Design and Optimization Graduate Intern
The Aerospace Corpor
Colorado Springs, CO
…technical deep dives, trade studies, and assessments to satisfy project objectives and tasks. Work Model This is a full-time position based in El Segundo, CA; Chantilly, VA; or Colorado…
Added 39 mins ago
2027 Space Control and Awareness Grad Intern
The Aerospace Corpor
Colorado Springs, CO
Added 39 mins ago
AI-Enabled Design Lead
The Aerospace Corpor
Colorado Springs, CO
…partnerships across the Engineering and Technology Group(ETG)and program officesto create revolutionary design capabilitiesfor our teamthat are both responsive and technically rigorous -…
Added 39 mins ago
2027 Space Control and Awareness Grad Intern
The Aerospace Corpor
Colorado Springs, CO
Added 39 mins ago
XE
Senior Category Manager
Xcel Energy
Denver, CO
- $97,600 to $138,600 USD / year
Develop and execute sourcing category, supplier, and risk management strategies that align with business stakeholder priorities for key categories. Lead cross functional teams from the…
Added 39 mins ago
XE
Principal Category Manager - Construction Services
Xcel Energy
Denver, CO
- $112,200 to $159,400 USD / year
Provide sourcing leadership and direction for complex, critical sourcing categories with the greatest impact. Lead cross functional teams to drive successful project and category…
Added 39 mins ago
PC
Human Resources Coordinator
PCL Construction
Denver, CO
- $67,000 to $87,000 USD / year
…projects, and that shared commitment drives how we work, grow and lead in the construction…
Added 39 mins ago
Senior Environmental Project Manager
Jacobs
Denver, CO
Manage multidisciplinary project teams and provide overall project delivery leadership, including scope, schedule, budget, quality, and risk management.
Added 39 mins ago
Manager - Catering Operations & Logistics
United Airlines
Denver, CO
…use of United Airlines’ equipment and materials, warehouse management practices, inventory ordering and stock management, as well as waste reduction efforts. United is focused and aligned…
Added 39 mins ago
XE
Principal Supply Chain Major Capital Project Specialist
Xcel Energy
Denver, CO
- $112,200 to $159,400 USD / year
Lead, develop, and execute large-scale engineering, procurement, & construction (EPC), engineered equipment, and construction services contract project sourcing strategies aligned with…
Added 39 mins ago
Lead Technical Project Manager HQ
Turner Construction
Denver, CO
Division: Headquarters Project Location(s): New York, NY 10001 USA Minimum Years Experience: Travel Involved: 0-10% Job Type: Regular Job Classification: Experienced Education: Bachelors…

AstraZeneca

Associate Director, NGS & Bioinformatics

Santa Monica, CA, United States
Santa Monica, United States

The annual base pay (or hourly rate of compensation) for this position ranges from $142,377 - $213,566 USD.

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Job details

Pay: The annual base pay (or hourly rate of compensation) for this position ranges from $142,377 - $213,566 USD.
Apply by: Apr 28, 2027
Experience: 6+ years of relevant pharmaceutical industry experience.
Posting language: English
Posted: Oct 30, 2026

Original job description

Are you ready to make a significant impact in the field of cell therapy? In AstraZeneca's Cell Therapy division, we follow the science to explore and innovate. We are working towards treating, preventing, modifying, and even curing some of the world's most complex diseases. We have the potential to grow our pipeline and positively impact the lives of patients around the world. We are committed to making a difference and have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs.

AstraZeneca is looking for an Associate Director to join the NGS & Bioinformatics group within Cell Therapy Translational and Safety Sciences (CT-TSS). In this role, you will provide scientific and analytical leadership for bioinformatics efforts that generate translational and safety insights across our cell therapy pipeline (CAR/TCR/in vivo). Your expertise will be crucial in advancing our cell therapy programs and transforming the lives of patients.

Accountabilities

Lead the single-cell RNA sequencing (scRNAseq)-based analyses to generate translational and safety science insights supporting the AstraZeneca cell therapy pipeline (CAR/TCR/in vivo).
Oversee the development and optimization of bioinformatics pipelines supporting single-cell transcriptomics and multi-omic data integration.
Apply and guide the use of AI/ML methodologies and advanced analytics to derive actionable insights from complex multi-modal datasets.
Develop, validate, and operationalize program-specific and cross-trial computational models that integrate longitudinal multi-omic and clinical data to address defined translational questions, including response prediction, mechanism-of-action characterization, biomarker discovery, and resistance profiling.
Lead the evaluation, adaptation, and implementation of AI foundation models for single-cell and multi-omic data, including domain-specific pretraining, fine-tuning, embedding-based representation learning, benchmarking, and deployment to support translational and safety applications across cell therapy programs.
Guide assay development teams on NGS assay design, sequencing strategy, data quality requirements, and analytical readiness.
Interpret and integrate complex datasets within and across programs; provide clear written and verbal updates on findings and their translational/safety implications to key stakeholders.
Contribute to regulatory-support materials, internal strategy documents, and publication strategy, including preparation of data for presentation at internal and external scientific conferences.
Collaborate cross-functionally with bioanalysis, clinical, data engineering, and IT teams to ensure robust data management, workflow orchestration, and compute scalability for NGS and bioinformatics workflows.
Stay current with advancements in single-cell technologies and AI and ML-based models, and apply this knowledge to continuously improve analytical approaches.
Mentor and provide scientific/technical guidance to junior scientists and bioinformaticians within the team.

Essential Skills/Experience

PhD in bioinformatics, computational biology, or a related field.
6+ years of relevant pharmaceutical industry experience.
Demonstrated expertise in bioinformatics and computational analysis of single-cell RNA sequencing (scRNAseq) and multi-omic datasets.
Experience generating translational and safety science insights from genomic/transcriptomic data within Cell Therapy, immunology, or tumor biology programs.
Deep understanding of Cell therapy Biology, immune cell phenotyping, and/or tumor biology, with up-to-date knowledge of analytical methods applicable to characterization of cell therapy products and their mechanism of action.
Deep familiarity with bioinformatics pipelines for single-cell and immune-profiling datasets.
Proficiency in programming languages such as Python and R, with experience building and maintaining analytical pipelines.
Experience with cloud computing environments and high-performance computing clusters for scalable data processing.
Background in applying AI/ML models to biological data, including prediction, feature extraction, and integrative multi-omic analytics.
Solid understanding of statistics and their application to biomedical science and clinical data.
Working knowledge of FAIR data principles, structured metadata, and harmonized data practices.
Exceptional ability to interpret and communicate complex datasets verbally, in writing, and in presentations, adapting to scientific, clinical, and executive audiences.
Ability to work cross-functionally and collaboratively with project stakeholders, and to prioritize multiple projects concurrently in a fast-paced environment.

The annual base pay (or hourly rate of compensation) for this position ranges from $142,377 - $213,566 USD. Our positions offer eligibility for various incentives - an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted 30-Oct-2026 Closing Date Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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More about this job

Skills

TSS
RNA sequencing
ML
Data engineering
Data management
Workflow
Pharmaceutical industry
Programming languages
Python
R
Cloud computing
Process data
Statistics
Biomedical science
Presentation skills
Sales

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