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Added 9 hours ago
Operations Coordinator
TriHealth
Montgomery, OH · Cincinnati, OH
This position is responsible for coordinating the ongoing non-clinical operational issues of assigned units/departments and provides administrative support to assigned directors and…
Added 1 day ago
Laboratory Technician II
Cleveland Clinic
Akron, OH
…abnormal cells in blood and body fluids. They use microscopes, cell counters, automated equipment and computerized analyzers in the clinical laboratory area. The laboratory findings are…
Added 1 day ago
Lab Technician III - Immunohistochemistry
Cleveland Clinic
Cleveland, OH
The following duties are specific to Anatomic Pathology: perform tasks involved with creating slides and/or cell blocks, perform frozen section processing (frozen section slide creation),…
Added 1 day ago
Research Assistant 2
Oregon Health & Science University
Portland, OR
…best predict drug responses in patients, helping to inform clinical care. You will be trained in growing primary cultures of tumor cells using advanced cell biology lab techniques,…
Added 1 day ago
Associate Quality Control Quality Microbiology, Cell Therapy
AstraZeneca Pharmaceuticals LP Company
Rockville, MD
…through environmental monitoring, microbial testing, and aseptic processing support. The role focuses on learning and performing routine activities with high quality and data integrity,…
Added 1 day ago
A
URGENTLY HIRING: GMP Scientist I
Actalent
Columbus, OH
- $24 USD / hour
Support all aspects of GMP operations and production in a clinical manufacturing facility focused on cell-based manufacturing.
Added 1 day ago
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URGENTLY HIRING: GMP Cell Scientist I
Actalent
Columbus, OH
- $24 USD / hour
Support all aspects of GMP operations and production in a clinical manufacturing facility focused on cell-based manufacturing.
Added 1 day ago
Associate Quality Control Quality Microbiology, Cell Therapy
AstraZeneca
Rockville, MD · Rockville
…through environmental monitoring, microbial testing, and aseptic processing support. The role focuses on learning and performing routine activities with high quality and data integrity,…
Added 1 day ago
TI Clinical Research Assistant
Oregon Health & Science University
Portland, OR
…complete responsibilities with oversight; performs routine clinical research tasks (e.g., tissue sample management, medical record acquisition, specimen processing); some innovation and…
Added 1 day ago
Manufacturing Manager
AstraZeneca Pharmaceuticals LP Company
Tarzana, CA
Coach, mentor, and develop Associate Specialists, Manufacturing Specialists, and Lead Cell Therapy Specialists.
Added 1 day ago
Cellular Therapy Lab Specialist
Community Health Network
IN
1+ years: Experience in clinical cell processing (Preferred)
Added 1 day ago
UO
Soc/Clin Research Assistant
University of North Carolina- Chapel Hill
NC
- $22 to $26 USD / hour
The Associate Clinical Research Coordinator position is to support clinical research in sickle cell disease and transfusion medicine through regulatory, administrative, patient…
Added 1 day ago
Claims Resolution Supervisor
Innovative Hematology, Inc.
Indianapolis, IN
IHI participates in national and international clinical research, including new infusion products and therapies, investigation of long-term outcomes, and the impact of associated…
Added 1 day ago
Manufacturing Manager
AstraZeneca
Tarzana, CA · Los Angeles, CA · Los Angeles
Coach, mentor, and develop Associate Specialists, Manufacturing Specialists, and Lead Cell Therapy Specialists.
Added 1 day ago
HV
Ranch Animal Health Associate
Heritage Vet Partners and their Partner Clinics
Flagstaff, AZ
- $20 USD / hour
All clinical work is done under Dr. Varnell's direction. The associate does not diagnose, prescribe, or sign any regulatory,
Added 1 day ago
Scientist II
ICON Clinical Research
New York, NY
Develops, qualifies, and validates a variety of immunological, biochemical, and cell-based methods with little direct supervision for supporting preclinical and clinical studies following…
Added 2 days ago
CP
Materials Control Associate III
Catalent Pharma Solutions LLC
Harmans, MD
- $26.44 to $31.25 USD / hour
We have an opportunity for a Material Control Associate III to join our team. In this role, you will support GMP materials control and warehousing operations for a Phase II/III biopharma…
Added 2 days ago
CP
Associate II, Materials Control
Catalent Pharma Solutions LLC
Harmans, MD
- $21.63 to $26.44 USD / hour
We have an opportunity for a Material Control Associate II to join our team. In this role, you will support GMP materials control and warehousing operations for a Phase II/III biopharma…
Added 2 days ago
Senior Specialist, Manufacturing NPI & Clinical Readiness-Bothell, WA
Military Spouse Jobs & VetJobs
United States
The Senior Specialist, Manufacturing NPI and Clinical Readiness, plays a key role in enabling clinical and commercial manufacturing readiness for cell therapy products through ownership of…
Added 2 days ago
Scientist II
ICR United States USA
NY
Develops, qualifies, and validates a variety of immunological, biochemical, and cell-based methods with little direct supervision for supporting preclinical and clinical studies following…
Added 2 days ago
LI
Residential Associate
LIFEWAYS INC
Ontario, OR
- $19.85 USD / hour
Performs all aspects of client belongings processing for new admissions and resulting from visitations, including search, debugging, and delivery.
Added 2 days ago
AP
Associate Specialist, Clinical Biologics
AstraZeneca Pharmaceuticals LP Company
Gaithersburg, MD
- $65,081.6 to $97,622.4 USD / year
…biomanufacturing function. At our Pilot Plant Facilities, our dynamic clinical manufacturing team performs bioprocessing operations for novel molecules to support the development of new…
Added 2 days ago
A
Associate Specialist, Clinical Biologics
AstraZeneca
Gaithersburg, MD · Gaithersburg
- $65,081.6 to $97,622.4 USD / year
…biomanufacturing function. At our Pilot Plant Facilities, our dynamic clinical manufacturing team performs bioprocessing operations for novel molecules to support the development of new…
Added 2 days ago
Per Diem Unit Secretary- Our Lady of Mercy
Trinity Health
Guilderland, NY
Have you ever walked on Smart Cell Flooring? Have you ever watched an Artificial Sky change throughout the day?
Added 2 days ago
TH
Unit Secretary - Full Time Days - Our Lady of Mercy
Trinity Health
Guilderland, NY
- Full-time
Have you ever walked on Smart Cell Flooring? Have you ever watched an Artificial Sky change throughout the day?

Closed listing

AstraZeneca

Associate Director, NGS & Bioinformatics

Santa Monica, CA, United States
Santa Monica, United States

The annual base pay (or hourly rate of compensation) for this position ranges from $142,377 - $213,566 USD.

This opening has closed.

The original listing is kept below for reference.

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Job details

Pay: The annual base pay (or hourly rate of compensation) for this position ranges from $142,377 - $213,566 USD.
Closing date: Apr 28, 2027
Experience: 6+ years of relevant pharmaceutical industry experience.
Posting language: English
Posted: Oct 30, 2026

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Original job description

Archived listing. The details below describe a past opening.

Are you ready to make a significant impact in the field of cell therapy? In AstraZeneca's Cell Therapy division, we follow the science to explore and innovate. We are working towards treating, preventing, modifying, and even curing some of the world's most complex diseases. We have the potential to grow our pipeline and positively impact the lives of patients around the world. We are committed to making a difference and have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs.

AstraZeneca is looking for an Associate Director to join the NGS & Bioinformatics group within Cell Therapy Translational and Safety Sciences (CT-TSS). In this role, you will provide scientific and analytical leadership for bioinformatics efforts that generate translational and safety insights across our cell therapy pipeline (CAR/TCR/in vivo). Your expertise will be crucial in advancing our cell therapy programs and transforming the lives of patients.

Accountabilities

Lead the single-cell RNA sequencing (scRNAseq)-based analyses to generate translational and safety science insights supporting the AstraZeneca cell therapy pipeline (CAR/TCR/in vivo).
Oversee the development and optimization of bioinformatics pipelines supporting single-cell transcriptomics and multi-omic data integration.
Apply and guide the use of AI/ML methodologies and advanced analytics to derive actionable insights from complex multi-modal datasets.
Develop, validate, and operationalize program-specific and cross-trial computational models that integrate longitudinal multi-omic and clinical data to address defined translational questions, including response prediction, mechanism-of-action characterization, biomarker discovery, and resistance profiling.
Lead the evaluation, adaptation, and implementation of AI foundation models for single-cell and multi-omic data, including domain-specific pretraining, fine-tuning, embedding-based representation learning, benchmarking, and deployment to support translational and safety applications across cell therapy programs.
Guide assay development teams on NGS assay design, sequencing strategy, data quality requirements, and analytical readiness.
Interpret and integrate complex datasets within and across programs; provide clear written and verbal updates on findings and their translational/safety implications to key stakeholders.
Contribute to regulatory-support materials, internal strategy documents, and publication strategy, including preparation of data for presentation at internal and external scientific conferences.
Collaborate cross-functionally with bioanalysis, clinical, data engineering, and IT teams to ensure robust data management, workflow orchestration, and compute scalability for NGS and bioinformatics workflows.
Stay current with advancements in single-cell technologies and AI and ML-based models, and apply this knowledge to continuously improve analytical approaches.
Mentor and provide scientific/technical guidance to junior scientists and bioinformaticians within the team.

Essential Skills/Experience

PhD in bioinformatics, computational biology, or a related field.
6+ years of relevant pharmaceutical industry experience.
Demonstrated expertise in bioinformatics and computational analysis of single-cell RNA sequencing (scRNAseq) and multi-omic datasets.
Experience generating translational and safety science insights from genomic/transcriptomic data within Cell Therapy, immunology, or tumor biology programs.
Deep understanding of Cell therapy Biology, immune cell phenotyping, and/or tumor biology, with up-to-date knowledge of analytical methods applicable to characterization of cell therapy products and their mechanism of action.
Deep familiarity with bioinformatics pipelines for single-cell and immune-profiling datasets.
Proficiency in programming languages such as Python and R, with experience building and maintaining analytical pipelines.
Experience with cloud computing environments and high-performance computing clusters for scalable data processing.
Background in applying AI/ML models to biological data, including prediction, feature extraction, and integrative multi-omic analytics.
Solid understanding of statistics and their application to biomedical science and clinical data.
Working knowledge of FAIR data principles, structured metadata, and harmonized data practices.
Exceptional ability to interpret and communicate complex datasets verbally, in writing, and in presentations, adapting to scientific, clinical, and executive audiences.
Ability to work cross-functionally and collaboratively with project stakeholders, and to prioritize multiple projects concurrently in a fast-paced environment.

The annual base pay (or hourly rate of compensation) for this position ranges from $142,377 - $213,566 USD. Our positions offer eligibility for various incentives - an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted 30-Oct-2026 Closing Date Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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More about this job

Skills

TSS
RNA sequencing
ML
Data engineering
Data management
Workflow
Pharmaceutical industry
Programming languages
Python
R
Cloud computing
Process data
Statistics
Biomedical science
Presentation skills
Sales

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