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Lead Data Engineer, Databricks (Remote, US)
V4C.ai
Remote, United States
- $120,000 to $140,000 USD / year
As a Lead Data Engineer, you will lead the build of production Lakehouse pipelines on customer engagements, working directly with customers and often Databricks' own field teams. Every…
Added 2 mins ago
Staff IT Auditor
Publix Super Markets, Inc.
Lakeland, FL
Lead independent audits and assessments of moderately complex technologies and processes.
Added 2 mins ago
Principal Engineer (agent framework)
Emergence AI
NY
We're hiring a Principal Engineer to shape where the platform goes, build it, and grow the team around it. In your first few months, you'll learn the platform's model deeply, challenge the…
Added 3 mins ago
RL
AI Engineer
R3 LLC
Remote, United States
- $170,000 to $185,000 USD / year
R3 is seeking an AI Engineer to design, implement, secure, and drive adoption of enterprise AI solutions. This role will have a strong focus on Microsoft Copilot, Copilot Studio, Azure AI,…
Added 3 mins ago
IC&E Engineer
Babcock & Wilcox Company
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An IC&E Engineer is responsible for instrumentation, controls, and electrical system design for boiler and
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Advanced Lead Engineer - Turbine Airfoil Design
GE Aerospace
Evendale, OH
This Advanced Lead Engineer role is for Turbine Airfoil design in support of a Military NPI program within Edison Works. The position reports to an Engineering manager in Evendale, OH with…
Added 3 mins ago
LCE Systems NPI Turbomachinery Integrator
GE Aerospace
Evendale, OH
…cross-organization integration efforts for all turbomachinery design Integrated Product Teams (IPTs) on advanced F110 platforms. As part of the NPI Systems subsection, this role offers a…
Added 3 mins ago
Staff Engineer - Turbine Rotor Design
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Evendale, OH
This Staff Engineer role is for Turbine Rotor design in support of a Military NPI program within Edison Works. The position reports to an Engineering manager in Evendale, OH with…
Added 3 mins ago
Staff Engineer - Turbine Airfoil Design
GE Aerospace
Evendale, OH
This Staff Engineer role is for Turbine Airfoil design in support of a Military NPI program within Edison Works. The position reports to an Engineering manager in Evendale, OH with…
Added 3 mins ago
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RF & Test Engineer - Aerospace
Saint-Gobain
RAVENNA, OH
- $92,000 to $142,000 USD / year
Join our Aerospace team where engineering excellence meets customer impact. As our RF & Test Engineer in Ravenna, OH , you will be the primary subject matter expert for all RF design,…
Added 3 mins ago
Design Engineering Lead - Aerospace
Saint-Gobain
RAVENNA, OH
Join our Aerospace team where engineering excellence meets customer impact. As our- Design Engineering Lead located in Ravenna, Ohio you will provide technical expertise to both management…
Added 3 mins ago
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Senior Software Engineer
KeyBank
Brooklyn, OH
- $80,000 to $150,000 USD / year
Transmit Developer (Transmit Security Engineer)
Added 3 mins ago
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Design Manager, Rail + Transit
T.Y. Lin International
CA
- $160,000 to $230,000 USD / year
TYLin is seeking an experienced Design Manager to support the continued growth and delivery of our Rail & Transit practice in California. This is an opportunity for an accomplished…
Added 3 mins ago
GE9X HPT Metal Airfoils - Lead Engineer
GE Aerospace
West Chester, OH
Lead execution of hardware-related tasks and small to medium scope engineering projects that support design maturation, producibility, manufacturing support, test readiness, and cost…
Added 3 mins ago
Sr NPI Manufacturing Engineer
Intuitive
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We are seeking a collaborative and technically strong Manufacturing Process Engineer to support next-generation needles and accessories for advanced bronchoscopic instruments. In this role,…
Added 4 mins ago
Model Based Systems Engineer (MBSE)
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MTSI is seeking a highly skilled Model-Based Systems Engineer (MBSE) to support an advanced air platform program. at Wright Patterson Air Force Base in Dayton, OH. This role involves the…
Added 4 mins ago
Consulting/Principal Software Engineer
RELX INC
Dayton, OH
Serve as a primary technical point of contact for external technology resources. Provide design input across a product. Work directly with customers and end users. Serve as acknowledged "go…
Added 4 mins ago
Mechanical Engineer, High-Spec Water
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Tustin, CA
The High-Spec Water Mechanical Engineer is responsible for the design, specification, technical assurance, and delivery of complex water and wastewater mechanical systems across high value,…
Added 4 mins ago
Senior Project Manager
Terracon
North Charleston, SC
Design, communicate, and implement a project plan for completing a project.
Added 4 mins ago
Senior Manager, Ignition - Tax Data Engineer
KPMG LLP
McLean, VA · Washington, DC
KPMG is currently seeking a Senior Manager, Ignition - Tax Data Engineer to join our Tax Ignition practice.
Added 6 mins ago
Project Engineer - Aircraft
Whisper Aero
Nashville or Crossville, TN
Whisper Aero is seeking a Project Engineer who will work with cross-functional engineering teams within Whisper to coordinate timing and execution of projects in Tennessee. In this role,…
Added 6 mins ago
Senior Development Scientist
Corning
Wilmington, NC
The Sr Development Engineer is responsible for leading or working within multi-discipline teams to prototype and pilot equipment designs for optical fiber manufacturing processes and…
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Process Engineer NPI
Corning
Phoenix, AZ
We are seeking an experienced Process Engineer to improve manufacturing performance in a solar module production facility. The successful candidate will provide hands-on technical…
Added 7 mins ago
Lead Data Engineer, Databricks (Remote, US)
V4C.ai
Remote, United States
As a Lead Data Engineer, you will lead the build of production Lakehouse pipelines on customer engagements, working directly with customers and often Databricks' own field teams. Every…
Added 9 mins ago
Electrical Design Engineer (Prime), Senior
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United States
…mission-driven team is seeking a bold and dynamic Electrical Design Engineer (Prime), Senior who is fueled by high accountability, execution horsepower, and driven to understand our world,…

Astera Institute

Software Engineer, Biomolecular Structure Software

Emerybille, CA, United States

$240,000 to $280,000 USD / year

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Job details

Pay: $240,000 to $280,000 USD / year
Experience: Bachelor’s degree in Computer Science or related field with at least 5 years of work experience.
Posting language: English
Posted: Nov 13, 2026

Original job description

ABOUT ASTERA

Astera is a private foundation on a mission to steer science and technology toward a better future. We believe the coming years will bring an era of unprecedented scientific and technological advancement as exponential progress in AI converges with central advances in other fields to accelerate innovation. This inflection point provides an unparalleled opportunity to fundamentally rethink the institutions, systems, and tools that drive progress. We have committed a $3.5B endowment to that work and fit the form of our support to the function it serves: grants, investments, and in-house research programs. We accept meaningful risk in the research we back and expect some of it to fail because transformative ideas are rarely the ones already proven. Our projects, and the foundation itself, operate like high-velocity startups, with a high performance bar and competitive compensation to match. We are searching for leaders who are compelled by the challenge of driving high-impact change in the way science is funded, conducted, and communicated. You can read more about our mission, vision, and programming at astera.org/vision http://astera.org/vision.

TEAM OVERVIEW

Prism is making protein motion measurable, predictable, and actionable. Proteins are always moving, and that movement drives their function: binding, catalysis, allostery, selectivity, and mutational effects all emerge from conformational ensembles, the distribution of states a protein moves between. Yet most structural data rests on static snapshots that capture form, not function, because motion has been hard to measure and interpret. That has left us without critical levers to correct proteins in disease or engineer them for new purposes. We are building a team of structural biologists, computational scientists, and engineers to develop open tools, methods, and infrastructure for studying protein dynamics from experimental data. By combining experimental measurement, ensemble modeling, and machine learning, we aim to move structural biology from describing what proteins look like to predicting how they behave.

Prism sits within Radial, Astera's life sciences division (https://astera.org/radial/).

POSITION SUMMARY

The Astera Institute’s Prism project seeks a full-time on-site software engineer to lead design and development of new software tools for working with biomolecular structures and experimental data used for biomolecular structure determination in a machine-learning friendly way. The successful candidate will be involved in API design, architecture, and implementation of the package, as well as refactoring existing software to use the new tools. This position reports to the Machine Learning Team Lead.

This is a full-time position.

RESPONSIBILITIES

Reviewing existing APIs and codebases to identify constraints and needs
Reviewing existing requirements and translating them into a final API, and building consensus both within Prism and externally around that API
Working with scientists to define requirements.
Working with Prism and external scientists to identify where existing software libraries can be used and what must be built new.
Working with Prism and external scientists to ensure correctness of any calculations performed on structures and data.
Writing Python code to implement software, and possibly C/C++ libraries as needed for high performance, including GPU kernels written with CUDA

QUALIFICATIONS AND EXPERIENCE

Bachelor’s degree in Computer Science or related field with at least 5 years of work experience.
Experience building new software packages from the ground up.
A track record of building software for critical scientific applications.
Experience collaborating with scientists from diverse backgrounds.
Experience working with machine learning pipelines, data preparation, etc. (experience training ML models is not required).
Nice to have: experience with structural biology data.

CULTURAL ALIGNMENT

Surprising problem-solver – you love finding unexpected solutions to problems we don't even know we have, and see options where others only see constraints.
Flexible by default – you don't draw hard lines around your job description and expect requirements to evolve.
Bias to action – when in doubt, you build and test an idea.
High standards, internally driven – you don’t settle for the first thing that seems to work, you come up with new ways to break it to make sure it is correct.
Open to feedback – you create opportunities to give and receive honest feedback, staying focused on both personal and team growth.
Operate with the highest levels of integrity, judgment, and stewardship - you treat peers, collaborators, and vendors with genuine respect for their time and contributions.
Embrace the tools that define great work today – Astera is building for an AI-driven future and equips the team accordingly.

LOCATION

This position is on-site at our Emeryville, CA location. Some travel (10%) may be required from time-to-time for in-person collaboration and work.

COMPENSATION

This role's pay range is $240,000 – $280,000 per year, based on experience, skills, and location.

BENEFITS

Benefits include:

Top tier health insurance plans with 99% of premiums covered by Astera for employees and dependents
Daily lunch that brings the full office together, plus a well-stocked fridge and pantry
Licenses for frontier AI tools and software
403(b) retirement plans, flexible paid time off, paid parental leave, commuter benefits, and health and dependent care FSAs

EQUAL OPPORTUNITY EMPLOYMENT & ACCOMMODATIONS

Astera Institute is an equal opportunity employer and is invested in fostering a culture where everyone can thrive. We are committed to equity and inclusion, and we encourage women, people of color, LGBTQIA individuals, people with disabilities, members of ethnic minorities, foreign-born residents, older members of society, and others from minority communities and diverse backgrounds to apply.

Astera Institute is committed to providing reasonable accommodations for qualified individuals with disabilities in the job application and interview process. If you need an accommodation, please contact us at recruiting@astera.org and we will work with you to meet your needs.

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Jobs in the United States