Jobs in the United States

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Added 1 hour ago
PN
Data Scientist (Nuclear Physics)
Pacific Northwest National Laboratory
Richland, WA
- $114,000 USD / year
Our Science & Technology directorates include National Security, Earth and Biological Sciences, Physical and Computational Sciences, and Energy and Environment. In addition, we have an…
Added 1 hour ago
2027 Quantitative Masters Internship Program - Investments - Portfolio Management - San Francisco
BlackRock
San Francisco, CA
…problem-solving.Eligibility: Students enrolled in analytics, computational finance, financial engineering, mathematics and/or a quantitative-disciplined master’s program and graduating…
Added 3 hours ago
TT
Lead Platform Engineer
True Talent Solutions Partners
San Francisco, CA
- $220,000 to $300,000 USD / year
On-site in San Francisco, California, five days per week
Added 6 hours ago
Systems Engineer (Research and Development Scientist and Engineer 2)
Stanford
Stanford, CA
Added 6 hours ago
Business Development Manager
Axiomatic_AI
Axiomatic_AI Middlesex County Cambridge, MA
Previous experience as a scientist, physicist, or engineer before transitioning into business development, technical sales, or other customer-facing commercial roles.
Added 7 hours ago
IC
AI Frameworks Engineer
Intel Corporation
CA · OR
- $133,410 to $240,710 USD / year
You must possess the below minimum qualifications to be initially considered for this position
Added 8 hours ago
2027 Quantitative Masters Internship Program - Investments - Portfolio Management - Atlanta
BlackRock
Atlanta, GA
…problem-solving.Eligibility: Students enrolled in analytics, computational finance, financial engineering, mathematics and/or a quantitative-disciplined master’s program and graduating…
Added 8 hours ago
Senior Manager, Thermal Design Engineering
Celestica International LP
Austin, TX
…every day. Through our Hardware Platform Solutions (HPS), we engineer and deliver leading-edge networking, storage, and server platforms - powering everything from custom hyperscale cloud…
Added 8 hours ago
Senior Engineer, Design Verification
Samsung Semiconductor
San Jose, CA
…developing scalable platforms that can effectively handle the computational and memory requirements of these workloads while minimizing energy consumption and maximizing performance. To…
Added 9 hours ago
Mechanical Engineer
Actalent
Hagerstown, MD
Job Title: Mechanical EngineerJob DescriptionThis Mechanical Engineer role focuses on researching, designing, developing, testing, certifying, deploying, and improving cutting-edge products…
Added 10 hours ago
Cable and Optics Engineer
Dell
Hopkinton, MA
…hardware and software that connect infrastructure, accelerate computational workloads, integrate across the stack, protect data continuity, and deliver the platforms, applications, and…
Added 10 hours ago
AI
Software Engineer, Biomolecular Structure Software
Astera Institute
Emerybille, CA
- $240,000 to $280,000 USD / year
…us without critical levers to correct proteins in disease or engineer them for new purposes. We are building a team of structural biologists, computational scientists, and engineers to…
Added 10 hours ago
GI
Senior AI Engineer
Genentech, Inc.
United States
- $168,100 to $312,300 USD / year
This role is based in South San Francisco and offers a hybrid schedule working 3 day per week on campus
Added 10 hours ago
CS
Graduate AI/Machine Learning Engineer Intern (TX, NJ, MO)
Cigna-Evernorth Services Inc.
Austin, TX · Morris Plains, NJ · St. Louis, MO
- $35 to $43 USD / hour
Location: This internship follows a hybrid schedule with three days per week in the Austin, TX; Morris Plains, NJ; or St
Added 11 hours ago
O
Senior Full-Stack Software Engineer
OXMAN
New York City, NY
- $141,500 to $177,000 USD / year
This role sits at the intersection of web engineering, spatial data and applied AI. The engineer will help build a platform where a client picks a site, writes a brief in plain language,…
Added 11 hours ago
Senior Solutions Engineer, CFD
Raydar
Remote, United States
Raydar is recruiting for this role on behalf of our client. Work directly with engineering customers to scope and shape computational fluid dynamics solutions, leading technical discovery,…
Added 12 hours ago
KC
Associate Test Engineer 2
KLA Corporation
Milpitas, CA
- $28.85 to $49.04 USD / hour
We provide advanced inspection tools, metrology systems, process solutions, and computational analytics that make electronics possible, tackling complex challenges. From electron and photon…
Added 13 hours ago
Senior Principal Mechanical Engineer (Modular Data Center Architecture)
Dell
Hopkinton, MA · Round Rock, TX
…hardware and software that connect infrastructure, accelerate computational workloads, integrate across the stack, protect data continuity, and deliver the platforms, applications, and…
Added 13 hours ago
Senior Director, Project and Alliance Management
Flagship Pioneering, Inc.
Cambridge, MA
…DELVE™ platform combines a viral-protein knowledge graph and computational design with high-throughput, automated testing to discover, characterize and engineer novel proteins with…
Added 13 hours ago
Research and Development Biomedical Engineer
University of Mississippi
University, MS
…Diagnostics, Design, Devices and Biomechanics (D3B) is seeking a R&D Engineer to lead the design, development, and testing of medical devices from concept through validation within the…
Added 19 hours ago
J
Senior Embedded Computer Vision Engineer
Jobgether
Remote, United States
- $155,000 to $180,000 USD / year
…Our partner is looking for a Senior Embedded Computer Vision Engineer based in the United…
Added 22 hours ago
Intern, Compiler Engineer
Samsung Semiconductor
San Jose, CA
…developing scalable platforms that can effectively handle the computational and memory requirements of these workloads while minimizing energy consumption and maximizing performance. To…
Added 1 day ago
Senior Machine Learning Engineer
Xenon7
Remote, United States
We are seeking a Senior Machine Learning Engineer with extensive experience in production MLOps, model deployment, and system scaling to drive ML engineering initiatives for a top-tier life…
Added 1 day ago
Senior Machine Learning Engineer
Xenon7
Remote, United States
We are seeking a Senior Machine Learning Engineer with extensive experience in production MLOps, model deployment, and system scaling to drive ML engineering initiatives for a top-tier life…
Added 1 day ago
Senior Machine Learning Engineer
Xenon7
Remote, United States
We are seeking a Senior Machine Learning Engineer with extensive experience in production MLOps, model deployment, and system scaling to drive ML engineering initiatives for a top-tier life…

Astera Institute

Software Engineer, Biomolecular Structure Software

Emerybille, CA, United States

$240,000 to $280,000 USD / year

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Job details

Pay: $240,000 to $280,000 USD / year
Experience: Bachelor’s degree in Computer Science or related field with at least 5 years of work experience.
Posting language: English
Posted: Nov 13, 2026

Original job description

ABOUT ASTERA

Astera is a private foundation on a mission to steer science and technology toward a better future. We believe the coming years will bring an era of unprecedented scientific and technological advancement as exponential progress in AI converges with central advances in other fields to accelerate innovation. This inflection point provides an unparalleled opportunity to fundamentally rethink the institutions, systems, and tools that drive progress. We have committed a $3.5B endowment to that work and fit the form of our support to the function it serves: grants, investments, and in-house research programs. We accept meaningful risk in the research we back and expect some of it to fail because transformative ideas are rarely the ones already proven. Our projects, and the foundation itself, operate like high-velocity startups, with a high performance bar and competitive compensation to match. We are searching for leaders who are compelled by the challenge of driving high-impact change in the way science is funded, conducted, and communicated. You can read more about our mission, vision, and programming at astera.org/vision http://astera.org/vision.

TEAM OVERVIEW

Prism is making protein motion measurable, predictable, and actionable. Proteins are always moving, and that movement drives their function: binding, catalysis, allostery, selectivity, and mutational effects all emerge from conformational ensembles, the distribution of states a protein moves between. Yet most structural data rests on static snapshots that capture form, not function, because motion has been hard to measure and interpret. That has left us without critical levers to correct proteins in disease or engineer them for new purposes. We are building a team of structural biologists, computational scientists, and engineers to develop open tools, methods, and infrastructure for studying protein dynamics from experimental data. By combining experimental measurement, ensemble modeling, and machine learning, we aim to move structural biology from describing what proteins look like to predicting how they behave.

Prism sits within Radial, Astera's life sciences division (https://astera.org/radial/).

POSITION SUMMARY

The Astera Institute’s Prism project seeks a full-time on-site software engineer to lead design and development of new software tools for working with biomolecular structures and experimental data used for biomolecular structure determination in a machine-learning friendly way. The successful candidate will be involved in API design, architecture, and implementation of the package, as well as refactoring existing software to use the new tools. This position reports to the Machine Learning Team Lead.

This is a full-time position.

RESPONSIBILITIES

Reviewing existing APIs and codebases to identify constraints and needs
Reviewing existing requirements and translating them into a final API, and building consensus both within Prism and externally around that API
Working with scientists to define requirements.
Working with Prism and external scientists to identify where existing software libraries can be used and what must be built new.
Working with Prism and external scientists to ensure correctness of any calculations performed on structures and data.
Writing Python code to implement software, and possibly C/C++ libraries as needed for high performance, including GPU kernels written with CUDA

QUALIFICATIONS AND EXPERIENCE

Bachelor’s degree in Computer Science or related field with at least 5 years of work experience.
Experience building new software packages from the ground up.
A track record of building software for critical scientific applications.
Experience collaborating with scientists from diverse backgrounds.
Experience working with machine learning pipelines, data preparation, etc. (experience training ML models is not required).
Nice to have: experience with structural biology data.

CULTURAL ALIGNMENT

Surprising problem-solver – you love finding unexpected solutions to problems we don't even know we have, and see options where others only see constraints.
Flexible by default – you don't draw hard lines around your job description and expect requirements to evolve.
Bias to action – when in doubt, you build and test an idea.
High standards, internally driven – you don’t settle for the first thing that seems to work, you come up with new ways to break it to make sure it is correct.
Open to feedback – you create opportunities to give and receive honest feedback, staying focused on both personal and team growth.
Operate with the highest levels of integrity, judgment, and stewardship - you treat peers, collaborators, and vendors with genuine respect for their time and contributions.
Embrace the tools that define great work today – Astera is building for an AI-driven future and equips the team accordingly.

LOCATION

This position is on-site at our Emeryville, CA location. Some travel (10%) may be required from time-to-time for in-person collaboration and work.

COMPENSATION

This role's pay range is $240,000 – $280,000 per year, based on experience, skills, and location.

BENEFITS

Benefits include:

Top tier health insurance plans with 99% of premiums covered by Astera for employees and dependents
Daily lunch that brings the full office together, plus a well-stocked fridge and pantry
Licenses for frontier AI tools and software
403(b) retirement plans, flexible paid time off, paid parental leave, commuter benefits, and health and dependent care FSAs

EQUAL OPPORTUNITY EMPLOYMENT & ACCOMMODATIONS

Astera Institute is an equal opportunity employer and is invested in fostering a culture where everyone can thrive. We are committed to equity and inclusion, and we encourage women, people of color, LGBTQIA individuals, people with disabilities, members of ethnic minorities, foreign-born residents, older members of society, and others from minority communities and diverse backgrounds to apply.

Astera Institute is committed to providing reasonable accommodations for qualified individuals with disabilities in the job application and interview process. If you need an accommodation, please contact us at recruiting@astera.org and we will work with you to meet your needs.

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Jobs in the United States