Jobs in the United States

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Added 4 mins ago
E
Project Manager - Distribution
Exelon
OAKBROOK TERRACE, IL
- $83,200 USD / year
Manage (or support a Principal or Senior Project Manager with the management of) transmission, substation, distribution, gas, and/or information technology projects consisting of…
Added 4 mins ago
Renewal and Reporting Analyst
CVS Health
Remote, United States
High attention to detail and accuracy, while focusing on overall project deliverables.
Added 5 mins ago
Associate Director, Business Insights Lead
AbbVie
North Chicago, IL
Reporting to the Director, Strategy, Analytics & Business Insights (SABI), the Associate Director, Business Insights serves as the primary analytical and strategic partner to the Clinical…
Added 5 mins ago
CG
HVAC LEAD TECH
Compass Group, North America
Aurora, IL
- $50 to $55 USD / hour
o Supports project management activity as needed.
Added 5 mins ago
Clinical Testing Automation Analyst
Highmark Health
Springfield, IL
The Associate Technical Analyst supports the development, execution, and maintenance of automated testing solutions that improve the quality, reliability, and efficiency of clinical and…
Added 5 mins ago
Senior Product Owner
Humana
Springfield, IL
5 years or more of experience representing business or technology in technology implementations and/or product/project management experience
Added 5 mins ago
Lead Product Owner
Humana
Springfield, IL
2+ years of project, product, or initiative leadership experience.
Added 5 mins ago
Senior Contract Tools, Education, Processes Professional
Humana
Springfield, IL
…complex to complex issues regarding technical approach for project components, and work is performed without direction. You will be responsible for writing policies and procedures regarding…
Added 5 mins ago
Sr Technician
HNTB Corporation
Salt Lake City, UT · Las Vegas, NV · Denver, CO
…and conducting complete projects of varied scope. Assists the project management team in outlining objectives, requirements and design approaches. Responsible for gathering engineering or…
Added 5 mins ago
Associate Cobol Technical Analyst
Highmark Health
Springfield, IL
…collaboration with customers to understand capability needs, gather project specifications, create business cases and cost sheet analysis, translate high-level business needs into detailed…
Added 5 mins ago
Cybersecurity, Privacy and Forensics - Palo Alto Networks XSIAM Engineer
PwC
Chicago, IL
As a Senior Associate, you will leverage your skills to build meaningful client connections and navigate complex situations. You will anticipate the needs of your teams and clients,…
Added 5 mins ago
DIR OF INFORMATION SYSTEMS
City of Chicago
Chicago, IL
…and maintenance of IT systems, including several computer, project and data management systems, that support DPD and DOH’s mission-critical functions. The IT Director must be a collaborator…
Added 5 mins ago
ENGINEERING TECHNICIAN VI
City of Chicago
Chicago, IL
…Sidewalk Program, 311 Sidewalk Inspection, Aldermanic Menu project…
Added 5 mins ago
CULTURAL AFFAIRS COORD II
City of Chicago
Chicago, IL
Graduation from an accredited college with an Associate’s degree in Fine Arts, Arts Administration, Liberal Arts, or a directly related field, PLUS four (4) years of program development or…
Added 5 mins ago
ASSISTANT DIRECTOR - Human Resources
City of Chicago
Chicago, IL
· Graduation from an accredited college with an Associate’s degree in a field related to the duties
Added 5 mins ago
Principal Associate, Supplier Management
Capital One
Chicago, IL · Riverwoods, IL
At Capital One, our Enterprise Service Management (ESM) teams are seeking a Principal Associate, Supplier Managemen t . In ESM, we empower associates to deliver their best by cultivating a…
Added 5 mins ago
Deals Accelerated Solutions IT Associate
PwC
Chicago, IL
As a Deals Accelerated Solutions IT Associate you will support integration and platform architecture work that helps clients align technology solutions with business priorities, cost…
Added 5 mins ago
CG
Hospital Environmental Services Training&Development Manager
Compass Group, North America
Chicago, IL
- $70,000 to $80,000 USD / year
Excellent organizational, project management and time management skills.
Added 5 mins ago
Senior Product Delivery Associate-Workflow Services Aurora
JPMorgan Chase
Chicago, IL
As a Senior Product Delivery Associate in [Insert team name or sub-LOB], you are trusted with enabling the delivery of products in a stable and scalable way. Work with cross-function teams,…
Added 5 mins ago
Healthcare Financial Advisory Services Associate
Huron Consulting Group
Chicago, IL
Own project workstreams by structuring problems, prioritizing analyses, and delivering high-quality outputs under tight timelines
Added 5 mins ago
GA
Principal Technical Product Manager, Data & Platform
GE Aerospace
Arlington Heights, IL · Barrington, IL · Bloomington, IL · Chicago, IL · Loves Park, IL
- $152,000 to $222,000 USD / year
Own cost attribution. Monitor, analyze, and manage platform consumption and cost down to the usage account, project, and ontology level, with proactive reporting and usage controls (FinOps).
Added 5 mins ago
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Manager, Earned Influence & Brand PR
Kellanova
Chicago, IL
- $108,160 to $141,960 USD / year
…opportunities to amplify key brand moments internally and drive Associate…
Added 5 mins ago
GA
Sr Staff Applications Operations Engineer – Engineering Tools Automation & AI Ops
GE Aerospace
Barrington, IL · Arlington Heights, IL · Bloomington, IL · Chicago, IL · Loves Park, IL
- $131,000 to $174,000 USD / year
…application pods (software, hardware and electronic design, and project and portfolio management tools) for US and UK…
Added 7 mins ago
LH
Part Time - Loader/Cart Associate - Flexible
Lowe's Home Centers, LLC
South Lebanon, OH
- Part-time
Assists customers with locating, selecting, carrying, and loading merchandise while responding promptly to customers and associate questions
Added 7 mins ago
LH
Full Time - Merchandising Service Associate - Day
Lowe's Home Centers, LLC
NE
- Full-time
As a Lowe's Merchandising Services Associate, you are a key connection point between Merchandising and Store Operations, allowing us to deliver a great shopping experience in every Lowe's…

Amgen

Senior Manufacturing Systems Engineer - PLC Systems

Holly Springs, NC, United States

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Job details

Posting language: English
Posted: Jun 28, 2026

Original job description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission - to serve patients living with serious illnesses - drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Be part of Amgen's newest and most advanced drug substance manufacturing plant. When completed, the Amgen FleX batch facility will combine the latest in disposable technologies with traditional stainless steel equipment to allow for maximum flexibility in operations The FleX Batch facility will not only feature the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it will also integrate sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027.

Senior Manufacturing Systems Engineer – PLC

What you will do

In this vital role as a member of the Facilities & Engineering (F&E) group, you will lead technical projects, and drive innovation and support of PLC based processes and utility skid equipment automation needs. You will solve complex engineering problems and ensure the company's engineering efforts align with strategic objectives. You will also provide leadership and guidance to the Automation Engineering team supporting 24/7 manufacturing and facility operations.

You will partner closely with the capital project team to design, build, commission, and qualify new equipment and systems needed for drug substance production. This role will develop domain expertise to support operations upon start-up, focusing on manufacturing automation.

Job responsibilities include:

Site design, construction, start-up, and operational readiness:

Provide support to the capital project team with a strong focus on safety and on-time facility start-up.
Collaborate with the site process engineering team to understand key process requirements and develop process control automation solutions for PLC based systems.
Work with platform leads to ensure standalone PLC based systems are designed with the proper network connectivity and system-to-system communication to enable centralized monitoring and alarming.
Support commissioning and qualification efforts including Automation Installation Verification/Automation Check Out (IV/ACO).
Partner with various organizational units to support tasks including operational readiness, document reviews, deviation investigation and change controls.
Develop and maintain detailed specifications, SOPs and operating standards that impact multiple organizational units.
Provide mentoring to develop and accelerate site technical automation capabilities.

Site Operations:

Act as system owner for standalone PLC based systems.
Manage Day-to-day Operational Support including: 24 x 7 Onsite/On Call Operational Support, Troubleshooting Support to Plant and Mfg. Operations, preventive and corrective maintenance, system administration, and Automation System spare parts management
Lead and support functional area projects focused on improving equipment/utilities/facilities as well as capital projects to integrate new drug substance manufacturing technologies into the facility.
Lead and support technical root cause analysis, incident investigations, and troubleshooting on process control issues related to plant operations.
Lead and support new product introductions (NPI) or new technology introductions by performing automation engineering assessments, implementing automation system configuration changes and supporting engineering and process qualification runs as applicable.
Prepare and review Standard Operating Procedures (SOP) and cGMP documents.
On-site and up to 10% domestic/international travel

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The automation professional we seek is an engineer with these qualifications.

Basic Qualifications:

High School Diploma / GED and 10 years of Engineering experience OR
Associate’s Degree and 8 years of Engineering experience OR
Bachelor’s Degree and 4 years of Engineering experience OR
Master’s Degree and 2 years of Engineering experience OR
Doctorate Degree

Preferred Qualifications:

Degree in Electrical Engineering or Computer Science, Chemical Engineering or Biotech Engineering.
Extensive experience with process and utility skid equipment, and direct knowledge of integrating various OEM automation software and field instrumentation technologies such as Rockwell platforms.
Direct knowledge of integrating various OEM automation software and field instrumentation technologies.
Direct knowledge of Automation System design, experience in Process control engineering and troubleshooting with GMP biopharmaceutical production facility equipment/systems automation.
Experience in programming, design, installation and lifecycle management of PLC and field device/instrumentation technologies.
Extensive understanding and background in programming, design, installation and lifecycle management of manufacturing process controls, automation and field instrumentation technologies.
In-depth knowledge of industry standards such as 21 CFR Part 11, ASTM 2500, S88, S95, GAMP, GDP, and GMP.
Experience in Capital Project Lifecycle Management including conceptual design, basis of design, detailed design, implementation, and validation.
The ideal individual must be a self-directed team player ready to mentor and develop engineering staff and embrace a team-based culture that relies on collaboration for effective decision-making.
Strong leadership, technical writing, and communication/presentation skills.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.

Apply now and make a lasting impact with the Amgen team!

careers.amgen.com

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

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More about this job

Skills

PLC
Leadership
Process engineering
Control engineering
Communication skills
Coaching
Troubleshooting
System administration
Root cause analysis
Electrical engineering
Computer science
Chemical engineering
Good manufacturing practices
Manufacturing processes
Collaboration
Decision making
Technical writing
Presentation skills
Compensation and benefits

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