Jobs in the United States

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Added 1 hour ago
Engineering Director
Bridgenext
UNAVAILABLE
At Bridgenext, we engineer Growth Operating Systems. Most enterprises have spent millions on their revenue stack and still aren't seeing the growth they expected.They have tools that…
Added 2 hours ago
TT
Founding AI Agent Engineer
True Talent Solutions Partners
San Francisco Bay Area, CA
- $150,000 to $220,000 USD / year
- Strong software engineering fundamentals, with a full-stack background and applied LLM experience.
Added 2 hours ago
Lead Platform Engineer (Full-Stack)
Young Basile
Troy, MI
Lead Platform Engineer (Full-Stack) (Troy, MI - Hybrid (Remote and In Person))
Added 3 hours ago
Senior Full Stack Java Engineer – Data Streaming
Charles Schwab
Southlake, TX
…latency, scalability, and reliability. Working across engineering, platform, quality assurance, production support, and business teams, you’ll translate complex needs into maintainable…
Added 3 hours ago
Software Engineer - Applications
Elorian
Palo Alto, CA
- Full-Lifecycle Ownership: A builder mindset with a bias for shipping quickly. Experience as a founding engineer, startup core contributor, or forward-deployed engineer is highly valued.
Added 3 hours ago
GTM Systems Engineer
Roboflow
Remote, United States
We’re hiring a GTM Systems Engineer to build and scale the systems our revenue team runs on, reporting into the Revenue Operations lead and working hand-in-hand with sales leadership,…
Added 4 hours ago
Agent Engineer
Clera
Remote, United States
…useful product experiences. This role spans agent systems, platform engineering, integrations, and full-stack product…
Added 4 hours ago
TT
Senior Forward Deployed Engineer
True Talent Solutions Partners
Redwood City, CA
- $215,000 to $290,000 USD / year
- Develop full-stack integrations with enterprise tools such as CRMs, ERPs, and scheduling systems.
Added 4 hours ago
M
Senior Software Engineer
myLaurel
Remote, United States
- $170,000 to $190,000 USD / year
Seeking an experienced Senior Software Engineer to help design, build, and scale mission-critical systems that empower our clinicians, field responders, and care coordination teams. In this…
Added 5 hours ago
C
Product Engineer (Consumer, Design-Heavy)
Clera
Remote, United States
- $200,000 to $350,000 USD / year
Own the full lifecycle of consumer products, from identifying user opportunities to shipping polished experiences and learning from real-world usage. This role combines product strategy,…
Added 5 hours ago
C
Senior/Staff Software Engineer, Platform
Clera
San Francisco, CA
- $160,000 to $250,000 USD / year
- Professional TypeScript experience and recent hands-on experience with Next.js, plus full-stack experience across Python and Go.
Added 5 hours ago
Senior Machine Learning Engineer
Amgen
Washington D.C., DC
Demonstrated experience building full-stack AI-powered applications that move beyond experimentation and are designed with scalability, security, evaluation, and maintainability in mind.
Added 6 hours ago
Foundry Developer
CACI International
Ashburn, VA
Palantir certifications. Data Engineer or Application Developer track.
Added 6 hours ago
Senior DevOps Engineer, Observability and FinOps
CACI International
Reston, VA
This engineer makes mission systems visible and their costs accountable, on networks that cannot call out to the internet. The role blends platform engineering (Kubernetes/OpenShift,…
Added 6 hours ago
Front-end Engineer 5
Capital One
McLean, VA
…public-facing digital marketing experiences using a modern front-end stack centered on Angular, TypeScript/JS, Semantic HTML, CSS/SCSS, and advanced content management systems. As an…
Added 6 hours ago
Full-stack Engineer 4, Tech College Engineering
Capital One
Richmond, VA · McLean, VA
…real problems and meet real customer needs. We are seeking Full-stack Software Engineers who are passionate about leveraging cutting-edge open source frameworks and emerging technologies.…
Added 7 hours ago
Full Stack Software Engineer II
SONY CORPORATE SERVICES GROUP INC
MADISON, WI
…name synonymous with entertainment excellence and creativity. Full Stack Software Engineer II (Contract Role) Madison, WI Playstation is looking for a Software Engineer to build our…
Added 7 hours ago
Full Stack Software Engineer II
SONY CORPORATE SERVICES GROUP INC
MADISON, WI
…name synonymous with entertainment excellence and creativity. Full Stack Software Engineer II (Contract Role) Madison, WI Playstation is looking for a Software Engineer to build our…
Added 7 hours ago
BH
Solutions Engineer
Beacon Hill Solutions Group
Saint Paul, MN
- $60 to $65 USD / hour
We're looking for a hands-on Solutions Engineer with a strong software development background who can build, test, integrate, and support enterprise technology solutions. This person should…
Added 7 hours ago
KL
Associate Director, AI Application Engineer
KPMG LLP
Minneapolis, MN
- $11.41 USD / hour
Strong full-stack development experience with modern technologies including C#, .NET, JavaScript, TypeScript, React.js, Node.js, HTML, and CSS
Added 7 hours ago
DA
Senior Software Development Engineer
Delta Air Lines, Inc.
Minneapolis, MN
- $81,300 to $221,000 USD / year
Write clean, efficient, and maintainable code and contribute to both front-end and back-end development as a full-stack engineer.
Added 8 hours ago
Staff Software Engineer
HENRY SCHEIN, INC.
SANDY, UT
…engineers, and driving reliability and scalability across the platform. You'll operate with little to no supervision, act as a subject-matter expert, and take on difficult, ambiguous…
Added 8 hours ago
Senior Software Development Engineer, IMDb Discovery Services
Amazon
Santa Monica, CA
Design and build the search, ranking, and list systems behind IMDb - the platform hundreds of millions of people use to find movies, shows, and talent. As a senior engineer, you'll own the…
Added 8 hours ago
T
Staff Software Engineer
TEKsystems
Mountain View, CA
- $80 to $95 USD / hour
8+ years of Full Stack development experience with React/TypeScript and Python, Go, or Java
Added 9 hours ago
S
Senior Full Stack Engineer, AI Products - Stout Strategy
Stout
Denver, CO
- $87,000 to $195,000 USD / year
As a Senior Full-Stack Engineer in our Applied Innovation Group, you get the best of both worlds: working at the frontier of AI and knowledge work, inside a firm with the clients, expertise…

Amgen

Senior Machine Learning Engineer

Washington D.C., DC, United States

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Job details

Posting language: English
Posted: Oct 1, 2026

Original job description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission - to serve patients living with serious illnesses - drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas – Oncology, Inflammation, General Medicine, and Rare Disease – we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lie within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Machine Learning Engineer

What you will do

Let’s do this. Let’s change the world. As part of the Artificial Intelligence & Data organization, the AI & Data Innovation Lab is a center for exploration and innovation, focused on integrating and accelerating new technologies and methods that deliver measurable value and competitive advantage. We move fast to prove what is possible, de-risk what is uncertain, and create the technical foundation that allows Amgen to scale the right AI solutions responsibly. Join us!

We are seeking a Senior Machine Learning Engineer to help build high-impact AI proofs-of-concept that are credible, scalable, secure, and designed with a clear path to production. This role sits at the intersection of AI engineering, software engineering, cloud and data architecture, product thinking, and business partnership. The ideal candidate is a hands-on builder who can operate through ambiguity, partner closely with product managers and business stakeholders, make pragmatic technical decisions, and raise the engineering bar for others. They should bring strong ownership and accountability, while understanding that success is not only shipping code, but also creating reusable patterns, validated architectures, and clear evidence that helps Amgen decide what to scale.

Key Responsibilities:

Build scalable AI proof-of-concepts that are designed to demonstrate a clear path from prototype to enterprise-scale solution.
Partner with product managers, business stakeholders, platform teams, and AI software engineers to translate ambiguous business needs into practical AI solutions with measurable value.
Design and implement modern AI systems using LLMs, agentic workflows, retrieval augmented generation, data pipelines, APIs, cloud-native services, and enterprise platforms.
Rapidly validate feasibility and value by assessing technical risk, data readiness, integration complexity, user experience, security considerations, performance, cost, and business impact.
Create reusable technical assets such as reference architectures, reusable components, documentation, decision records, and handoff materials that enable product, platform, or delivery teams to scale successful POCs.
Raise the technical bar for the team by modeling strong engineering practices, mentoring others, improving delivery patterns, and bringing clear ownership and accountability to uncertain, fast-moving work.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is an individual with these qualifications.

Basic Qualifications:

Doctorate degree

Master’s degree and 2 years of relevant experience

Bachelor’s degree and 4 years of relevant experience

Associate’s degree and 8 years of relevant experience

High school diploma / GED and 10 years of relevant experience

Preferred Qualifications:

4-6 years of relevant experience in AI engineering, machine learning engineering, software engineering, data engineering, cloud engineering, or related technical roles.
Demonstrated experience building full-stack AI-powered applications that move beyond experimentation and are designed with scalability, security, evaluation, and maintainability in mind.
Strong understanding of modern AI application architecture, including LLMs, retrieval-augmented generation, embeddings, vector databases, agentic workflows, tool use, orchestration frameworks, and AI evaluation methods.
Experience defining and applying evaluation methods for AI solutions, including accuracy, reliability, hallucination risk, latency, usability, safety, cost, and fitness for intended use.
Ability to translate ambiguous business problems into practical technical approaches, make sound tradeoffs, and rapidly validate feasibility, value, risks, and path to scale.
Experience with AWS Cloud, data pipelines, integration architecture, containers, CI/CD, observability, and secure development practices.
Strong software engineering foundation, preferably with Python and modern development practices, including testing, version control, modular design, documentation, and maintainable code.
Demonstrated ability to responsibly use AI tools to improve engineering productivity, explore technical solutions, automate repetitive tasks, and enhance the delivery of machine learning or software products.
Excellent communication, ownership, and cross-functional leadership skills, with the ability to partner effectively with product managers, business stakeholders, platform teams, and AI and software engineers.

What you can expect from us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

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