Jobs in the United States

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Added 15 mins ago
TT
Engineering Lead
True Talent Solutions Partners
San Francisco, CA
- $221,000 to $295,000 USD / year
- At least 6 years of full-stack software engineering experience, including 2 or more years as an engineering manager.
Added 17 mins ago
Senior Staff Full-stack Engineer - Global Payment Network (Remote - Eligible)
Capital One
Baton Rouge, LA
…rapidly deliver new features. Leveraging automation and AI-native engineering, you will unlock real-time insights and advance our capabilities in domains ranging from high-throughput…
Added 2 hours ago
AE
Sr Software Engineer I
American Express
Sunrise, FL
- $123,000 to $215,250 USD / year
Design, develop, and deliver scalable, high-quality software solutions across the full stack, leveraging Java and Python for enterprise-grade platforms and services
Added 2 hours ago
Senior Machine Learning Engineer
Amgen
Washington D.C., DC
Demonstrated experience building full-stack AI-powered applications that move beyond experimentation and are designed with scalability, security, evaluation, and maintainability in mind.
Added 3 hours ago
O
Senior Full Stack Developer (React.js, Python)
OpenDataJobs
Washington, DC
- $150,000 to $180,000 USD / year
…hard problems and deliver better outcomes. We work across the full lifecycle - from strategy and governance through architecture, engineering, analytics, AI, visualization, and training -…
Added 3 hours ago
O
Full Stack Developer (React.js, Python)
OpenDataJobs
Washington, DC
- $120,000 to $150,000 USD / year
Turn user stories into back-end features written in Python on a cloud-native AWS stack.
Added 5 hours ago
BA
Solution Architect, Lead
Booz Allen Hamilton
Aurora, CO
- $99,000 to $225,000 USD / year
Experience with React and Node.js for full-stack web applications
Added 5 hours ago
KL
Associate Director, AI Application Engineer
KPMG LLP
Minneapolis, MN
- $11.41 USD / hour
…applications and platform capabilities using .NET Core, C#, Python, and modern cloud-native…
Added 5 hours ago
DA
Senior Software Development Engineer
Delta Air Lines, Inc.
Minneapolis, MN
- $81,300 to $221,000 USD / year
…build, and scale next-generation applications leveraging cloud-native architectures, AI/ML capabilities, and modern engineering…
Added 6 hours ago
T
Staff Software Engineer
TEKsystems
Mountain View, CA
- $80 to $95 USD / hour
8+ years of Full Stack development experience with React/TypeScript and Python, Go, or Java
Added 6 hours ago
S
Senior Full Stack Engineer, AI Products - Stout Strategy
Stout
Denver, CO
- $87,000 to $195,000 USD / year
Five or more years of professional software engineering across the full stack: user interfaces, server-side logic, APIs, data stores and background processing, including running what you…
Added 8 hours ago
Senior Manager, Full-stack Engineer (People Leader)-EDT
Capital One
New York, NY
…real problems and meet real customer needs. We are seeking Full-stack Software Engineering leaders who are passionate about building high-performing teams, driving technical strategy and…
Added 8 hours ago
Software Engineer
Mphasis Corporation
NEW YORK, NY
Added 13 hours ago
Principal Engineer & Technical Lead - Azure / Containers
Aperia
Dallas, TX
…Microsoft Fabric, an AI-powered ingestion platform, new AI-native applications, and ongoing evolution of the products our clients rely on every day. The teams executing this work are…
Added 16 hours ago
Senior Forward Deployed Solution Engineer
Jobgether
Remote, United States
…reliable, production-ready technical solutions. This hands-on engineering role combines software development, Kubernetes infrastructure, cloud and bare-metal systems, networking, and AI…
Added 16 hours ago
Senior Staff Full-stack Engineer - Global Payment Network (Remote - Eligible)
Capital One
Jackson, MS
…rapidly deliver new features. Leveraging automation and AI-native engineering, you will unlock real-time insights and advance our capabilities in domains ranging from high-throughput…
Added 17 hours ago
Senior Manager, Full-stack Engineer-People Leader
Capital One
Cambridge, MA
…real problems and meet real customer needs. We are seeking Full-stack Software Engineering leaders who are passionate about building high-performing teams, driving technical strategy and…
Added 18 hours ago
K
Associate Director, AI Application Engineer
KPMG
Louisville, KY
- $7.25 USD / hour
…applications and platform capabilities using .NET Core, C#, Python, and modern cloud-native…
Added 18 hours ago
Director, GTM AI Engineering
Samsara
Remote, United States
As the Director, GTM AI Engineering you’ll run our AI Engineering team for GTM. You’ll work closely with Data Science, Analytics, and Data Engineering to serve Sales, Customer Success,…
Added 20 hours ago
I
Senior Data Scientist, Full Stack
IREN
San Francisco, CA
- $225,000 to $285,000 USD / year
The Senior Data Scientist, Full Stack enables the modernization of IREN’s global Supply Chain systems and tools portfolio. Reporting to the Director, Supply Chain Analytics & Engineering,…
Added 21 hours ago
C
Sr. Java Full Stack Developer
Cognizant
Columbus, OH
- $70,000 to $110,500 USD / year
As a Sr. Java Full Stack Developer, you will make an impact by designing, building, and scaling API-first, cloud-native applications and integrations using modern Java, AWS, React, and…
Added 21 hours ago
I
Data Scientist, Full Stack
IREN
San Francisco, CA
- $190,000 to $240,000 USD / year
The Data Scientist, Full Stack supports the modernization of IREN’s global Supply Chain systems and tools portfolio. Reporting to the Director, Supply Chain Analytics & Engineering, this…
Added 21 hours ago
T
Architect
TEKsystems
Hanover, MD
- $156,000 to $234,000 USD / year
Practice Architect ll (Full-time, Remote)Think of TEKsystems Global Services (TGS) as the growth solution for enterprises today. We unleash growth through technology, strategy, design,…
Added 21 hours ago
SR
Senior Full Stack Engineer, AI Products - Stout Strategy
Stout Risius Ross, LLC
Arlington, VA · Charlotte, NC · Houston, TX · Dallas, TX · Philadelphia, PA · NY · Boston, MA · Detroit, MI · Chicago, IL · Atlanta, GA · Washington, DC · Denver, CO
- $87,000 to $195,000 USD / year
Five or more years of professional software engineering across the full stack: user interfaces, server-side logic, APIs, data stores and background processing, including running what you…
Added 22 hours ago
SO
Principal Developer - OIT Internal Recruitment (Remote From Anywhere In CO)
State of Colorado
CO
- $122,000 to $137,000 USD / year
A minimum of seven (7) years of progressive software engineering experience across full-stack development, systems architecture, and support operations.

Amgen

Senior Machine Learning Engineer

Washington D.C., DC, United States

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Job details

Posting language: English
Posted: Oct 1, 2026

Original job description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission - to serve patients living with serious illnesses - drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas – Oncology, Inflammation, General Medicine, and Rare Disease – we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lie within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Machine Learning Engineer

What you will do

Let’s do this. Let’s change the world. As part of the Artificial Intelligence & Data organization, the AI & Data Innovation Lab is a center for exploration and innovation, focused on integrating and accelerating new technologies and methods that deliver measurable value and competitive advantage. We move fast to prove what is possible, de-risk what is uncertain, and create the technical foundation that allows Amgen to scale the right AI solutions responsibly. Join us!

We are seeking a Senior Machine Learning Engineer to help build high-impact AI proofs-of-concept that are credible, scalable, secure, and designed with a clear path to production. This role sits at the intersection of AI engineering, software engineering, cloud and data architecture, product thinking, and business partnership. The ideal candidate is a hands-on builder who can operate through ambiguity, partner closely with product managers and business stakeholders, make pragmatic technical decisions, and raise the engineering bar for others. They should bring strong ownership and accountability, while understanding that success is not only shipping code, but also creating reusable patterns, validated architectures, and clear evidence that helps Amgen decide what to scale.

Key Responsibilities:

Build scalable AI proof-of-concepts that are designed to demonstrate a clear path from prototype to enterprise-scale solution.
Partner with product managers, business stakeholders, platform teams, and AI software engineers to translate ambiguous business needs into practical AI solutions with measurable value.
Design and implement modern AI systems using LLMs, agentic workflows, retrieval augmented generation, data pipelines, APIs, cloud-native services, and enterprise platforms.
Rapidly validate feasibility and value by assessing technical risk, data readiness, integration complexity, user experience, security considerations, performance, cost, and business impact.
Create reusable technical assets such as reference architectures, reusable components, documentation, decision records, and handoff materials that enable product, platform, or delivery teams to scale successful POCs.
Raise the technical bar for the team by modeling strong engineering practices, mentoring others, improving delivery patterns, and bringing clear ownership and accountability to uncertain, fast-moving work.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is an individual with these qualifications.

Basic Qualifications:

Doctorate degree

Master’s degree and 2 years of relevant experience

Bachelor’s degree and 4 years of relevant experience

Associate’s degree and 8 years of relevant experience

High school diploma / GED and 10 years of relevant experience

Preferred Qualifications:

4-6 years of relevant experience in AI engineering, machine learning engineering, software engineering, data engineering, cloud engineering, or related technical roles.
Demonstrated experience building full-stack AI-powered applications that move beyond experimentation and are designed with scalability, security, evaluation, and maintainability in mind.
Strong understanding of modern AI application architecture, including LLMs, retrieval-augmented generation, embeddings, vector databases, agentic workflows, tool use, orchestration frameworks, and AI evaluation methods.
Experience defining and applying evaluation methods for AI solutions, including accuracy, reliability, hallucination risk, latency, usability, safety, cost, and fitness for intended use.
Ability to translate ambiguous business problems into practical technical approaches, make sound tradeoffs, and rapidly validate feasibility, value, risks, and path to scale.
Experience with AWS Cloud, data pipelines, integration architecture, containers, CI/CD, observability, and secure development practices.
Strong software engineering foundation, preferably with Python and modern development practices, including testing, version control, modular design, documentation, and maintainable code.
Demonstrated ability to responsibly use AI tools to improve engineering productivity, explore technical solutions, automate repetitive tasks, and enhance the delivery of machine learning or software products.
Excellent communication, ownership, and cross-functional leadership skills, with the ability to partner effectively with product managers, business stakeholders, platform teams, and AI and software engineers.

What you can expect from us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

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