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- $100,000 to $150,000 USD / year
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Amgen Inc.

Senior Manager, Reliability Engineering & Work Management

NC, United States

.Salary Range 148,715.15USD -201,202.85 USD

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Job details

Pay: .Salary Range 148,715.15USD -201,202.85 USD
Apply by: Nov 20, 2026
Posting language: English
Posted: Nov 6, 2026

Original job description

Career Category Engineering

Job Description

Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission - to serve patients living with serious illnesses - drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

SENIOR MANAGER, RELIABILITY ENGINEERING & WORK MANAGEMENT

What you will do Let’s do this. Let’s change the world. In this vital role you will be responsible for the department inclusive of asset management and reliability through the work order administrative, central inventory and reliability programs at the drug substance facility in ANC. You will be joining the Facilities & Engineering (F&E) team to partner closely with the Corporate Engineering team as well as all site functions. This role will lead and develop a multi-functional engineering operations organization responsible for:

Work order administration and CMMS process ownership
Asset maintenance planning and scheduling
Spare parts and MRO inventory strategy
Reliability engineering and predictive maintenance programs
Sustainability and energy optimization initiatives
Engineering KPI and business performance reporting

Establish long-range maintenance and asset reliability strategies aligned with site operational goals, regulatory compliance requirements, and enterprise engineering standards. Build a culture centered on safety, compliance, operational excellence, accountability, and continuous improvement.

The Senior Manager Work Order Administration CMMS Process Owner reports to the Director of the Amgen North Carolina Facilities & Engineering group.

Lead and develop a multi-functional engineering operations organization responsible for work order administration, CMMS governance, maintenance planning and scheduling, reliability engineering, central inventory management, and KPI reporting.
Lead the Central Inventory (equipment spare parts) program working closely with the Internal Service Provider as it relates to the overall MRO process supporting the site.
Lead the site reliability program, aligning on the network approach for the Amgen North Carolina reliability roadmap, implementing initiatives and own engineering KPIs and business reporting on program and site equipment health.
Establish long-range maintenance and asset reliability strategies aligned with site operational goals, regulatory compliance requirements, and enterprise engineering standards.
Identify opportunities for continuous improvement, recommend solutions, and manage implementation of initiatives to improve planning and scheduling accuracy and adherence and overall asset management program.
Collaborate with key customers and support groups regarding preventative maintenance activities and on time completion as well as manage aging work order backlog.
Collaborate with corporate network groups to improve planning and scheduling performance in addition to improving programs within CMMS, Central Inventory, and Reliability to meet business needs.
Provide direct supervision and oversight of work order safety programs and planning procedures.
Experience working in a regulated environment (e.g. cGMP, OSHA, EPA, etc.), experience interacting with regulatory agencies and inspectors, and familiarity with GMP quality systems/processes such as change control, non-conformances, corrective and preventative actions, and qualifications/validation
Strong leadership, technical writing, and communication/presentation skills.
Work schedule flexibility as required to support 24/7 operations, requiring occasional after-hours engineering coverage

What we expect of you We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a person with these qualifications.

Basic Qualifications:

High school diploma / GED and 12 years of engineering, maintenance, reliability, or CMMS experience OR
Associate’s degree and 10 years of engineering, maintenance, reliability, or CMMS experience OR
Bachelor’s degree and 8 years of engineering, maintenance, reliability, or CMMS experience OR
Master’s degree and 6 years of engineering, maintenance, reliability, or CMMS experience OR
Doctorate degree and 2 years of engineering, maintenance, reliability, or CMMS experience

In addition to meeting at least one of the above requirements, you must have a minimum of 2 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced above

Preferred Qualifications:

Bachelor’s or Master’s degree in Engineering, Reliability Engineering, Industrial Engineering, or related technical field
8+ years of experience in pharmaceutical, biotechnology, or other highly regulated manufacturing industries
5+ years of leadership experience in maintenance, reliability engineering, facilities engineering, or asset management
Demonstrated expertise with CMMS platforms such as SAP PM, Maximo, or equivalent systems
Demonstrated skills, knowledge and experience utilizing a computerized maintenance management system.
Strong understanding of reliability engineering principles and asset lifecycle management
Experience leading MRO inventory and spare parts optimization programs
Knowledge of predictive maintenance technologies and Industry 4.0 systems
Experience managing integrated service providers and contractor organizations
Proven ability to lead continuous improvement and operational excellence initiatives
Strong financial acumen including budget management, forecasting, and cost optimization
Experience with KPI development, data analytics, and business intelligence reporting tools
Demonstrated ability to influence across functions and communicate effectively with senior leadership
Strong understanding of cGMP regulations, EHS requirements, and data integrity expectations
Ability to work within Microsoft Excel and Brio or other Data query software
Proven troubleshooting, problem solving and investigational skills.
Demonstrated interpersonal and facilitation skills and ability to work in a collaborative team-based environment.
Ability to work with minimum direction.
Ability to manage multiple tasks and effectively set priorities.

What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

.Salary Range 148,715.15USD -201,202.85 USD

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