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Actalent

Sr. Clinical Project Manager

Frederick, MD, United States

$147,300 to $200,000 USD / year

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Job details

Pay: $147,300 to $200,000 USD / year
Posting language: English
Posted: Nov 6, 2026

Original job description

Sr. Clinical Project Manager (Home-Based / 100% Remote)

Overview

Join a growing global CRO and lead the successful delivery of complex clinical trials from start-up through closeout. As a Senior Clinical Project Manager, you will serve as the primary client contact, overseeing study execution, timelines, budgets, quality, and cross-functional teams to ensure projects are delivered on time, within scope, and to the highest standards.Must Have: 4+ years of recent Clinical Project Management experience within a CRO environment.

Key Responsibilities

Serve as the primary client contact and escalation point for assigned studies.
Lead cross-functional teams to deliver clinical trials on time, within budget, and in compliance with quality standards.
Develop and maintain project plans, timelines, risk mitigation strategies, and study metrics.
Manage study budgets, forecasting, profitability, and scope changes, including change orders.
Oversee vendors and functional partners to ensure successful study delivery.
Lead client meetings, project governance, and study status reporting.
Identify and proactively manage project risks, issues, and protocol-related challenges.
Ensure inspection readiness, eTMF quality, and adherence to regulatory and SOP requirements.
Support bid defenses, business development activities, and client presentations as needed.
Mentor team members and provide leadership across project teams.

Required Qualifications

Bachelor's degree in a life science, health-related field, or equivalent experience.
Minimum 7 years of clinical research experience.
Minimum 4 years of project management experience within a full-service CRO.
Proven experience managing global or multi-site clinical trials.
Strong understanding of clinical trial operations, study start-up, risk management, and quality oversight.
Demonstrated experience managing study budgets, forecasting, and financial performance.
Excellent client-facing communication, presentation, and leadership skills.
Ability to manage multiple priorities in a fast-paced environment.
Willingness to travel domestically and internationally as needed.

Preferred Qualifications

Experience leading complex Phase I-IV clinical trials.
Background in oncology, radiopharmaceuticals, cell therapy, or other complex therapeutic areas.
Experience participating in bid defenses and business development initiatives.
Strong knowledge of eTMF management, inspection readiness, and quality management processes.
Experience working with global study teams, vendors, and sponsors.

Job Type & LocationThis is a Permanent position based out of Frederick, MD. Pay and BenefitsThe pay range for this position is $147300.00 - $200000.00/yr. Individual compensation offered for this position within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, geographic location, internal equity, and other pertinent job-related factors.Comprehensive Medical, Dental & Vision Coverage - Generous employer contributions for employees and dependents, national Aetna plans, telehealth access, Delta Dental PPO options, and VSP vision coverage.

401(k) with Strong Employer Match - 4% employer match plus immediate 100% vesting through a Safe Harbor plan.

Flexible Time Off - Exempt employees receive uncapped "My Time" (MTO), while non-exempt employees receive 20 days PTO annually, paid holidays, personal days, and volunteer time off.

Family Planning & Parental Support - Infertility coverage, 8 weeks of paid maternity leave at 100% pay, 4 weeks of paid parental bonding leave, and up to $3,000 in adoption assistance per child.

Company-Paid Life & Disability Insurance - Basic life insurance and AD&D up to 1.5x salary (maximum $500,000) plus short- and long-term disability coverage at 60% of pay.

Health Savings Account (HSA) Contributions - Employees enrolled in the HDHP receive annual employer HSA contributions of $1,000 (individual) or $1,500 (family/employee-plus coverage).

Wellness & Employee Assistance Programs - Free 24/7 support through Headspace, including mental health resources, counseling support, legal/financial assistance, work-life services, and access to over 3,000 wellness resources Job Type & LocationThis is a Permanent position based out of Frederick, MD. Application DeadlineThis position is anticipated to close on Nov 16, 2026. Workplace TypeThis is a fully remote position.About Actalent

Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 20,000 consultants and 5,000 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. We are proud to be an Engineering News-Record (ENR) Top 500 Design Firm for our engineering design services and a ClearlyRated Best of Staffing® winner for both client and talent service.

The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email actalentaccommodation@actalentservices.com for other accommodation options.

San Francisco Fair Chance Ordinance:

Pursuant to the San Francisco Fair Chance Ordinance, for all positions located in the city and county of San Francisco, we will consider for employment qualified applicants with arrest and conviction records.

Massachusetts Lie Detector:

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Use of Artificial Intelligence (AI):

We may use Artificial Intelligence (AI) to support parts of our hiring process, including sourcing, screening, and evaluating candidates. AI helps assess applications and qualifications, but final decisions are made by our hiring team. By applying, you acknowledge and agree that your application may be reviewed using AI tools.

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More about this job

Skills

Clinical trials
Project management
Regulatory compliance
Forecasting
Reporting
Inspection
Sales
Presentation skills
Leadership
Clinical research
Risk management
Communication skills
Radiopharmaceuticals
Quality assurance procedures
Mental health
Counselling

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