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Added 1 min ago
ER
Program Manager
Executive Recruiting Group
San Luis Obispo, CA
- $170,000 to $190,000 USD / year
…Under existing PMO leadership, you will work alongside the Program Manager and project coordination team. PMO leadership, in alignment with SLO project leadership, will define your…
Added 1 min ago
Program Manager 2 (4040)
Navarro Inc.
Los Alamos, NM
The Program Manager 2 will provide strategic and tactical planning for moderately complex, multi-year program activities; coordinate resources across project teams, line organizations, and…
Added 2 mins ago
Haul Truck Driver / Rental Tech
ASCO Equipment
Abilene, TX
Troubleshoot and perform complex repairs correctly in the shop or field including pumps, hydraulics, engines, transmissions, HVAC, and electrical issues
Added 3 mins ago
Director Operations II
Dufry Careers
LOUISVILLE, KY
Referral program – refer a friend and earn a bonus
Added 3 mins ago
Sr. Manager, Global Partner Marketing Campaigns & Programs
Mimecast North America, Inc.
United States of America, MA
Mimecast Global Partner Marketing is looking for a Partner Marketing Campaigns & Programs Manager to own the strategy, design, and execution of our through-partner marketing engine across…
Added 3 mins ago
Human Resources Business Partner
Visual Comfort & Co.
Skokie, IL
Training & Development: A comprehensive and structured training program, complemented by ongoing education and opportunities for career advancement.
Added 4 mins ago
Civil Construction Inspector
Arcadis
Columbus, OH
…many curious minds, together we can solve the world’s most complex challenges and deliver more impact…
Added 5 mins ago
SI
Architecture Advisor Senior Manager (multiple positions available)
SAP IT Business Systeme
Newtown Square, PA
- $213,990 to $300,365 USD / year
Job Title: Architecture Advisor Senior Manager (multiple positions available)
Added 5 mins ago
SI
IT Technology Services Senior Specialist (multiple positions available)
SAP IT Business Systeme
Newtown Square, PA
- $127,525 to $216,128 USD / year
Architecture, implementation, and administration of complex SAP landscapes including ECC, S/4HANA, BW/4HANA, PI/PO, Solution Manager, SLT, GBT, GTS, and DP Agent, across Dev, QA, and Prod…
Added 5 mins ago
CC
General Manager
Community Choice Financial Family of Brands
Payson, AZ
- $24 USD / hour
General Manager Check Into Cash Payson, Arizona
Added 5 mins ago
CC
General Manager
Community Choice Financial Family of Brands
Kentwood, MI
- $19.25 USD / hour
As a General Manager (GM), you’ll provide reliable financial solutions to help customers manage everyday challenges. As the driving force behind the store’s success, you’ll manage daily…
Added 5 mins ago
CC
Gerente General Bilingüe
Community Choice Financial Family of Brands
Tucson, AZ
- $24 USD / hour
Paid on-the-job training and a comprehensive new hire program.
Added 5 mins ago
CC
General Manager
Community Choice Financial Family of Brands
Terre Haute, IN
- $19.25 USD / hour
General Manager Check Into CashTerre Haute, IN
Added 6 mins ago
Radiation Protection Supervisor(HR-0625 & 0626)
SOCCo
Piketon, OH
…Protection Dosimetry group as assigned by the Radiation Protection Manager. Typical job responsibilities include assisting and supporting management in all aspects of supplying dosimetry…
Added 6 mins ago
Technical Program Manager
Rochester Precision Opt
West Henrietta, NY
Technical Program Managers are responsible for leading complex customer programs from contract award through final delivery, ensuring technical, operational, financial, and customer…
Added 8 mins ago
Manager, Procurement - Innovation (HDM)
Kraft Foods Group Brands LLC Company
Chicago, IL
Advanced storytelling and communication skills, with the ability to turn complex ideas into clear, compelling messages for different audiences. Strong written, verbal, and analytical…
Added 8 mins ago
Clinical Research Coordinator 2
University of Chicago
Chicago, IL
Facilitates and participates in the daily activities of moderately complex clinical studies and performs various activities including patient data retrieval, documenting clinical research…
Added 9 mins ago
SW
(USA) Optical Manager, Licensed – Sam’s Club. $5,000 SIGN-ON BONUS. Full-Time. Bowling Green, KY. $32.00+ USD Hourly
Sam's West, Inc.
KY
- $32 to $44 USD / hour
- Full-time
…safety protocols. Manages quality assurance processes, resolves complex optical issues under applicable optometric supervision, and maintains equipment calibration, cleanliness, and…
Added 10 mins ago
Haul Truck Driver / Rental Tech
ASCO Equipment
Abilene, TX
Troubleshoot and perform complex repairs correctly in the shop or field including pumps, hydraulics, engines, transmissions, HVAC, and electrical issues
Added 10 mins ago
Radiology Registered Nurse (RN) - Radiology Administration -PRN, Day Shift
Beacon Health System
South Bend, IN
As a Registered Nurse, you’ll report to the Director or Manager to provide professional nursing services in the area of assignment, assess the needs of patients and initiates, and implement…
Added 12 mins ago
Community Banking Manager
S&T Bank
United States
Coaches, guides and mentors branch team members in the more complex phases of their work, including their personal development and career planning.
Added 13 mins ago
A
Senior Network Administrator
AECOM
Miami, FL
- $115,000 to $155,000 USD / year
…consulting firm, partnering with clients to solve the worldâs most complex challenges and build legacies for future…
Added 13 mins ago
A
Network Operations Monitoring Specialist
AECOM
Atlanta, GA
- Up to $26.62 USD / hour
…powered by deep technical abilities, we solve our clients’ complex challenges in water, environment, energy, transportation and buildings. Our teams partner with public- and private-sector…
Added 14 mins ago
SMO Business Partner
projects/helpful-passage-853/companies/5eac5651-3998-4682-9f47-a0bde77d570a
Irving, TX
…candidates from all backgrounds and experience levels. PURPOSE As a Program Business Partner in the Strategic Management Office (SMO) this position plays a vital role in ensuring that the…
Added 17 mins ago
Customer Experience Manager - Telehealth
Health-eCommerce.com
United States
The Customer Experience Manager is responsible for the day-to-day leadership and performance of Patiently's customer experience function. This role leads the frontline support operation and…

Actalent

Senior Clinical Trial Manager

South San Francisco, CA, United States

$100 to $125 USD / hour

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Job details

Pay: $100 to $125 USD / hour
Education: Bachelor’s degree
Experience: Minimum of 10 years of clinical operations experience, including at least 3+ years in a Clinical Trial Manager or similar role.
Posting language: English
Posted: Nov 5, 2026

Original job description

Job Title: Sr Clinical Trial ManagerJob DescriptionThe Sr Clinical Trial Manager leads the planning, start-up, execution, and close-out of global clinical trials, with a strong focus on rare and ultra-rare disease programs. This role serves as the primary operational contact for contract research organizations (CROs), vendors, and study sites, ensuring that all study activities adhere to protocols, standard operating procedures, ICH-GCP guidelines, and regulatory requirements. The position requires a seasoned clinical operations professional who can drive complex Phase IIII trials, proactively manage risk, and collaborate across functions to deliver high-quality results on time and within budget.Responsibilities

Lead the planning, initiation, execution, and close-out of global clinical trials, ensuring operational excellence at every stage.
Serve as the primary operational contact for CROs, external vendors, and investigational sites, fostering strong, collaborative relationships.
Ensure all study activities comply with study protocols, SOPs, ICH-GCP guidelines, and applicable regulatory requirements.
Track and manage study timelines, enrollment targets, budgets, and key milestones, proactively identifying and mitigating risks to study delivery.
Support the development, review, and maintenance of core study documents, including protocols, Investigators Brochures (IBs), informed consent forms (ICFs), site tools, and operational plans.
Coordinate cross-functional communication among clinical, regulatory, data management, and other stakeholders to maintain alignment and efficient study execution.
Plan and conduct regular study team meetings, providing clear status updates and risk assessments to internal leadership.
Oversee vendor performance, monitor deliverables, and ensure contractual obligations and quality standards are consistently met.
Collaborate with clinical operations leadership to identify, recommend, and implement process improvements that enhance efficiency and quality.
Troubleshoot operational issues as they arise, developing solutions and escalating concerns when necessary to maintain study continuity.
Drive both strategic planning and hands-on tactical execution, demonstrating a willingness to engage in detailed operational tasks as needed.

Essential Skills

Minimum of 10 years of clinical operations experience, including at least 3+ years in a Clinical Trial Manager or similar role.
Proven experience managing global Phase IIII clinical trials in clinical research, pharmaceuticals, or biotechnology settings.
Experience working on rare or ultra-rare disease clinical programs, with rare neurodegenerative disease experience strongly preferred.
Strong understanding of Good Clinical Practice (GCP), ICH guidelines, and relevant regulatory requirements governing clinical trials.
Demonstrated ability to oversee CROs and vendors, including performance management and deliverable oversight.
Deep knowledge of clinical trial processes, from start-up through close-out, including site activation, enrollment, monitoring, and data lock.
Excellent written and verbal communication skills, with the ability to present clear updates and influence cross-functional stakeholders.
Strong organizational skills, with the ability to manage multiple complex studies, timelines, and competing priorities.
Advanced problem-solving skills, with a proactive approach to risk identification and mitigation.
Ability to work independently, take initiative, and drive study execution with minimal supervision.
A hands-on, roll-up-your-sleeves mindset and comfort handling both strategic and operational tasks.

Additional Skills & Qualifications

Bachelors degree in life sciences or a related field is required; an advanced degree is a plus.
Experience with global rare disease clinical trials, ideally in neurology, is highly desirable.
Exp in clinical research within pharmaceuticals or biotech environments.
Proven success collaborating with cross-functional teams, including clinical, regulatory, data management, and biostatistics.
Strong interpersonal skills and the ability to build effective relationships with internal teams, CROs, vendors, and study sites.

Work EnvironmentThis position is based in a local office environment with an expectation to work onsite approximately three to four times per week. The role involves regular interaction with cross-functional colleagues, CROs, and external vendors, supported by standard clinical trial technologies and communication tools. The work setting is professional and collaborative, with a focus on delivering high-quality global studies in rare and ultra-rare diseases. Job Type & LocationThis is a Contract position based out of South San Francisco, CA. Pay and BenefitsThe pay range for this position is $100.00 - $125.00/hr. Individual compensation offered for this position within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, geographic location, internal equity, and other pertinent job-related factors.Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits

available for this temporary role may include the following:

Medical, dental & vision Critical Illness, Accident, and Hospital 401(k) Retirement Plan Pre-tax and Roth post-tax contributions available Life Insurance (Voluntary Life & AD&D for the employee and dependents) Short and long-term disability Health Spending Account (HSA) Transportation benefits Employee Assistance Program Time Off/Leave (PTO, Vacation or Sick Leave) Job Type & LocationThis is a Contract position based out of South San Francisco, CA. Application DeadlineThis position is anticipated to close on Nov 14, 2026. Workplace TypeThis is a hybrid position in South San Francisco,CA.About Actalent

Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 20,000 consultants and 5,000 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. We are proud to be an Engineering News-Record (ENR) Top 500 Design Firm for our engineering design services and a ClearlyRated Best of Staffing® winner for both client and talent service.

The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email actalentaccommodation@actalentservices.com for other accommodation options.

San Francisco Fair Chance Ordinance:

Pursuant to the San Francisco Fair Chance Ordinance, for all positions located in the city and county of San Francisco, we will consider for employment qualified applicants with arrest and conviction records.

Massachusetts Lie Detector:

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Use of Artificial Intelligence (AI):

We may use Artificial Intelligence (AI) to support parts of our hiring process, including sourcing, screening, and evaluating candidates. AI helps assess applications and qualifications, but final decisions are made by our hiring team. By applying, you acknowledge and agree that your application may be reviewed using AI tools.

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